Protein: DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain (DC-1 alpha chain) (DC-alpha) (HLA-DCA) (MHC class II DQA1)

Gene: DQA1, HLA-DQA1
Organism: Homo sapiens
Interactions: 139
UniProt ID: P01909

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0002250 - adaptive immune response
GO:0002503 - peptide antigen assembly with MHC class II protein complex
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

354802

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

4

20

Small-scale

0.908

High

182243

TPSN
Tapasin

1

20

High-throughput

0.691

High

354651

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

19

High-throughput

0.691

High

354800

DQA2
HLA class II histocompatibility antigen, DQ alpha 2 chain

1

19

High-throughput

0.691

High

354805

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

19

High-throughput

0.691

High

354809

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

19

High-throughput

0.691

High

354824

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

19

High-throughput

0.691

High

354845

DRB5
HLA class II histocompatibility antigen, DR beta 5 chain

1

19

High-throughput

0.691

High

354877

IGSF8
Immunoglobulin superfamily member 8

1

3

High-throughput

0.691

High

121428

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

0

High-throughput

0.656

High

354808

CD14
Monocyte differentiation antigen CD14

1

0

High-throughput

0.656

High

354825

EFNB1
Ephrin-B1

3

3

High-throughput

0.656

High

354838

KCNJ8
ATP-sensitive inward rectifier potassium channel 8

3

2

High-throughput

0.656

High

354860

TM219
Insulin-like growth factor-binding protein 3 receptor

3

1

High-throughput

0.656

High

354869

MFSD8
Major facilitator superfamily domain-containing protein 8

3

4

High-throughput

0.656

High

354900

ST7
Suppressor of tumorigenicity 7 protein

3

2

High-throughput

0.656

High

354804

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

19

High-throughput

0.618

High

354812

FCERA
High affinity immunoglobulin epsilon receptor subunit alpha

1

5

High-throughput

0.618

High

354875

VPP1
V-type proton ATPase 116 kDa subunit a 1

2

1

High-throughput

0.611

High

354879

S22AI
Solute carrier family 22 member 18

2

5

High-throughput

0.611

High

354886

PGAP4
Post-GPI attachment to proteins factor 4

2

3

High-throughput

0.611

High

354907

DD19B
ATP-dependent RNA helicase DDX19B

2

1

High-throughput

0.611

High

354911

S27A6
Long-chain fatty acid transport protein 6

2

3

High-throughput

0.611

High

354913

VPP2
V-type proton ATPase 116 kDa subunit a 2

2

1

High-throughput

0.611

High

354819

CUX1
Homeobox protein cut-like 1

3

3

High-throughput

0.599

High

354854

TM214
Transmembrane protein 214

3

2

High-throughput

0.599

High

354856

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

3

3

High-throughput

0.599

High

354810

CD8B
T-cell surface glycoprotein CD8 beta chain

1

0

High-throughput

0.586

High

354803

HG2A
HLA class II histocompatibility antigen gamma chain

2

9

Small-scale

0.584

High

354866

S38A9
Neutral amino acid transporter 9

2

1

High-throughput

0.584

High

354881

MYO19
Unconventional myosin-XIX

2

3

High-throughput

0.584

High

354241

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

20

High-throughput

0.575

High

354864

MACOI
Macoilin

2

1

High-throughput

0.558

High

354821

CDK7
Cyclin-dependent kinase 7

1

4

High-throughput

0.541

High

354884

SH3G2
Endophilin-A1

1

1

High-throughput

0.541

High

354916

NEMO
NF-kappa-B essential modulator

1

2

High-throughput

0.541

High

58779

T131L
Transmembrane protein 131-like

1

9

High-throughput

0.536

High

163717

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

11

High-throughput

0.536

High

199571

B4GT5
Beta-1,4-galactosyltransferase 5

1

3

High-throughput

0.536

High

217121

EXTL3
Exostosin-like 3

1

6

High-throughput

0.536

High

234760

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

4

High-throughput

0.536

High

238835

TPST2
Protein-tyrosine sulfotransferase 2

1

1

High-throughput

0.536

High

253446

PLXA2
Plexin-A2

1

19

High-throughput

0.536

High

253875

FKTN
Ribitol-5-phosphate transferase FKTN

1

1

High-throughput

0.536

High

274894

RENR
Renin receptor

1

2

High-throughput

0.536

High

314806

LARG1
Xylosyl- and glucuronyltransferase LARGE1

1

6

High-throughput

0.536

High

318336

ECEL1
Endothelin-converting enzyme-like 1

1

8

High-throughput

0.536

High

320755

SEM4F
Semaphorin-4F

1

12

High-throughput

0.536

High

354811

ADT1
ADP/ATP translocase 1

1

9

High-throughput

0.536

High

354813

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

1

High-throughput

0.536

High

354815

MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

3

High-throughput

0.536

High

354817

CALX
Calnexin

1

11

High-throughput

0.536

High

354818

SCNNA
Amiloride-sensitive sodium channel subunit alpha

1

14

High-throughput

0.536

High

354820

MA2A2
Alpha-mannosidase 2x

1

4

High-throughput

0.536

High

354823

PLXA3
Plexin-A3

1

15

High-throughput

0.536

High

354828

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.536

High

354830

HYAL2
Hyaluronidase-2

1

1

High-throughput

0.536

High

354832

STIM1
Stromal interaction molecule 1

1

4

High-throughput

0.536

High

354833

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

4

High-throughput

0.536

High

354834

MOGS
Mannosyl-oligosaccharide glucosidase

1

1

High-throughput

0.536

High

354836

PON2
Serum paraoxonase/arylesterase 2

1

4

High-throughput

0.536

High

354840

EXT1
Exostosin-1

1

6

High-throughput

0.536

High

354841

MA2A1
Alpha-mannosidase 2

1

4

High-throughput

0.536

High

354855

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

9

High-throughput

0.536

High

354857

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

3

High-throughput

0.536

High

354858

GALT7
N-acetylgalactosaminyltransferase 7

1

9

High-throughput

0.536

High

354859

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

4

High-throughput

0.536

High

354861

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

9

High-throughput

0.536

High

354862

PLPL6
Patatin-like phospholipase domain-containing protein 6

1

3

High-throughput

0.536

High

354863

LARG2
Xylosyl- and glucuronyltransferase LARGE2

1

5

High-throughput

0.536

High

354867

CHSTE
Carbohydrate sulfotransferase 14

1

11

High-throughput

0.536

High

354868

NLGN2
Neuroligin-2

1

2

High-throughput

0.536

High

354870

GPX8
Probable glutathione peroxidase 8

1

2

High-throughput

0.536

High

354871

SCRB1
Scavenger receptor class B member 1

1

4

High-throughput

0.536

High

354876

PIGT
GPI transamidase component PIG-T

1

1

High-throughput

0.536

High

354888

CNTP3
Contactin-associated protein-like 3

1

4

High-throughput

0.536

High

354889

ABCA2
ATP-binding cassette sub-family A member 2

1

5

High-throughput

0.536

High

354890

SEM4C
Semaphorin-4C

1

12

High-throughput

0.536

High

354891

LMA2L
VIP36-like protein

1

2

High-throughput

0.536

High

354893

SPNS1
Protein spinster homolog 1

1

1

High-throughput

0.536

High

354894

SEM6B
Semaphorin-6B

1

12

High-throughput

0.536

High

354895

S38AA
Solute carrier family 38 member 10

1

5

High-throughput

0.536

High

354897

AT132
Polyamine-transporting ATPase 13A2

1

16

High-throughput

0.536

High

354899

ITM2C
Integral membrane protein 2C

1

8

High-throughput

0.536

High

354901

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

1

9

High-throughput

0.536

High

354904

LCAP
Leucyl-cystinyl aminopeptidase

1

8

High-throughput

0.536

High

354905

PLXA1
Plexin-A1

1

14

High-throughput

0.536

High

354906

DSE
Dermatan-sulfate epimerase

1

2

High-throughput

0.536

High

354912

DOP2
Protein dopey-2

1

1

High-throughput

0.536

High

354914

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

7

High-throughput

0.536

High

354915

S12A7
Solute carrier family 12 member 7

1

1

High-throughput

0.536

High

354806

GALT
Galactose-1-phosphate uridylyltransferase

2

1

High-throughput

0.533

High

354822

APLP1
Amyloid beta precursor like protein 1

1

0

High-throughput

0.518

High

354807

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.513

High

354826

B4GN1
Beta-1,4 N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.513

High

354839

VAS1
V-type proton ATPase subunit S1

1

0

High-throughput

0.513

High

354843

ALG11
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

1

0

High-throughput

0.513

High

354853

RRAGB
Ras-related GTP-binding protein B

1

0

High-throughput

0.513

High

354874

EDA
Ectodysplasin-A

1

0

High-throughput

0.513

High

354885

APOL2
Apolipoprotein L2

1

0

High-throughput

0.513

High

354892

F234A
Protein FAM234A

1

0

High-throughput

0.513

High

354898

GPC5C
G-protein coupled receptor family C group 5 member C

1

0

High-throughput

0.513

High

354908

MGT4B
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.513

High

354829

TLE1
Transducin-like enhancer protein 1

1

2

High-throughput

0.494

High

49119

TM223
Transmembrane protein 223

1

2

High-throughput

0.489

High

265491

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

High-throughput

0.489

High

314534

ATS2
A disintegrin and metalloproteinase with thrombospondin motifs 2

1

4

High-throughput

0.489

High

314934

SGPL1
Sphingosine-1-phosphate lyase 1

1

2

High-throughput

0.489

High

354816

FKBP2
Peptidyl-prolyl cis-trans isomerase FKBP2

1

3

High-throughput

0.489

High

354837

UBE3C
Ubiquitin-protein ligase E3C

1

2

High-throughput

0.489

High

354842

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

6

High-throughput

0.489

High

354844

VWC2
Brorin

1

2

High-throughput

0.489

High

354848

MKS3
Meckelin

1

6

High-throughput

0.489

High

354849

TM201
Transmembrane protein 201

1

2

High-throughput

0.489

High

354865

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.489

High

354872

ELYS
Protein ELYS

1

3

High-throughput

0.489

High

354880

TECT2
Tectonic-2

1

6

High-throughput

0.489

High

354882

P121A
Nuclear envelope pore membrane protein POM 121

1

4

High-throughput

0.489

High

354887

PXL2A
Peroxiredoxin-like 2A

1

2

High-throughput

0.489

High

354903

PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial

1

1

High-throughput

0.489

High

354909

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

2

High-throughput

0.489

High

354910

DJC16
DnaJ homolog subfamily C member 16

1

10

High-throughput

0.489

High

245471

NSMA
Sphingomyelin phosphodiesterase 2

1

3

High-throughput

0.479

High

354827

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

1

High-throughput

0.479

High

354878

T106A
Transmembrane protein 106A

1

15

High-throughput

0.479

High

354852

RIF1
Telomere-associated protein RIF1

1

1

High-throughput

0.457

High

354835

CASP
Protein CASP

1

4

High-throughput

0.445

High

354896

SEM4B
Semaphorin-4B

1

17

High-throughput

0.445

High

354814

COT2
COUP transcription factor 2

1

3

High-throughput

0.437

High

354902

DKK2
Dickkopf-related protein 2

1

1

High-throughput

0.437

High

354831

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.282

High

208440

OREX
Hypocretin neuropeptide precursor

1

0

High-throughput

0.279

Low

282392

STC2
Stanniocalcin-2

1

0

High-throughput

0.279

Low

354846

DB110
Beta-defensin 110

1

0

High-throughput

0.279

Low

354847

MBRL
Membralin

1

0

High-throughput

0.279

Low

354851

DIK1A
Divergent protein kinase domain 1A

1

0

High-throughput

0.279

Low

354873

CCL17
C-C motif chemokine 17

1

0

High-throughput

0.279

Low

354883

CP2S1
Cytochrome P450 2S1

1

0

High-throughput

0.279

Low

354850

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024