Protein: PTPRD
Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48)

Gene: PTPRD
Organism: Homo sapiens
Interactions: 129
UniProt ID: P23468

Gene Ontology (top 5):
GO:0004725 - protein tyrosine phosphatase activity
GO:0005001 - transmembrane receptor protein tyrosine phosphatase activity
GO:0005102 - signaling receptor binding
GO:0005886 - plasma membrane
GO:0006470 - protein dephosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

246337

SCN2B
Sodium channel subunit beta-2

3

6

High-throughput

0.861

High

255217

ICOSL
ICOS ligand

2

7

High-throughput

0.811

High

616969

CD83
CD83 antigen

2

1

High-throughput

0.811

High

616984

LRRN1
Leucine-rich repeat neuronal protein 1

2

4

High-throughput

0.811

High

616988

LIGO2
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2

2

4

High-throughput

0.811

High

616999

LIRB4
Leukocyte immunoglobulin-like receptor subfamily B member 4

2

5

High-throughput

0.811

High

616971

PTPRS
Receptor-type tyrosine-protein phosphatase S

2

17

Small-scale

0.800

High

200339

LRRT2
Leucine-rich repeat transmembrane neuronal protein 2

2

7

High-throughput

0.789

High

616970

LIPA1
Liprin-alpha-1

2

11

Small-scale

0.786

High

337941

EGFR
Epidermal growth factor receptor

2

20

High-throughput

0.783

High

160385

AURKA
Aurora kinase A

1

0

Small-scale

0.722

High

617011

SLIK1
SLIT and NTRK-like protein 1

1

3

Small-scale

0.710

High

616944

EPHA8
Ephrin type-A receptor 8

1

20

Small-scale

0.692

High

616959

KC1D
Casein kinase I isoform delta

1

3

Small-scale

0.692

High

616962

BMX
Cytoplasmic tyrosine-protein kinase BMX

1

20

Small-scale

0.692

High

616987

MARK2
Serine/threonine-protein kinase MARK2

1

2

Small-scale

0.692

High

121444

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

2

High-throughput

0.691

High

412016

FYN
Tyrosine-protein kinase Fyn

1

20

High-throughput

0.691

High

456806

FURIN
Furin

1

2

High-throughput

0.691

High

616942

IL3RA
Interleukin-3 receptor subunit alpha

1

18

High-throughput

0.691

High

616946

RYK
Tyrosine-protein kinase RYK

1

20

High-throughput

0.691

High

616948

TGFR2
TGF-beta receptor type-2

1

3

High-throughput

0.691

High

616953

KI2L1
Killer cell immunoglobulin-like receptor 2DL1

1

1

High-throughput

0.691

High

616977

TIGIT
T-cell immunoreceptor with Ig and ITIM domains

1

1

High-throughput

0.691

High

616990

MILR1
Allergin-1

1

8

High-throughput

0.691

High

617025

NLGN3
Neuroligin-3

1

4

High-throughput

0.691

High

616954

LPAR6
Lysophosphatidic acid receptor 6

3

3

High-throughput

0.667

High

616940

OMGP
Oligodendrocyte-myelin glycoprotein

1

6

Small-scale

0.647

High

617021

IL1AP
Interleukin-1 receptor accessory protein

1

9

Small-scale

0.647

High

616993

PIANP
PILR alpha-associated neural protein

2

1

High-throughput

0.628

High

616994

IZUM1
Izumo sperm-egg fusion protein 1

2

1

High-throughput

0.628

High

616996

PCD20
Protocadherin-20

2

18

High-throughput

0.628

High

617013

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

2

1

High-throughput

0.628

High

617023

PCDBG
Protocadherin beta-16

2

16

High-throughput

0.628

High

617032

PCDGG
Protocadherin gamma-B4

2

17

High-throughput

0.628

High

616967

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

4

High-throughput

0.625

High

255236

LIPA3
Liprin-alpha-3

1

11

Small-scale

0.621

High

259637

LIPA2
Liprin-alpha-2

1

13

Small-scale

0.621

High

616961

KC1E
Casein kinase I isoform epsilon

1

4

Small-scale

0.619

High

616963

NEK2
Serine/threonine-protein kinase Nek2

1

4

Small-scale

0.619

High

616964

PLK1
Serine/threonine-protein kinase PLK1

1

2

Small-scale

0.619

High

616976

SMTL2
Smoothelin-like protein 2

1

2

Small-scale

0.619

High

617010

TSSK2
Testis-specific serine/threonine-protein kinase 2

1

3

Small-scale

0.619

High

617012

NEK1
Serine/threonine-protein kinase Nek1

1

9

Small-scale

0.619

High

617020

NEK6
Serine/threonine-protein kinase Nek6

1

3

Small-scale

0.619

High

617022

PAK6
Serine/threonine-protein kinase PAK 6

1

1

Small-scale

0.619

High

617030

TBK1
Serine/threonine-protein kinase TBK1

1

7

Small-scale

0.619

High

259496

LRRN2
Leucine-rich repeat neuronal protein 2

1

6

High-throughput

0.618

High

616943

TPP2
Tripeptidyl-peptidase 2

1

2

High-throughput

0.618

High

616983

POTEA
POTE ankyrin domain family member A

1

4

High-throughput

0.618

High

279839

TRIO
Triple functional domain protein

1

2

High-throughput

0.618

High

617026

IRPL1
Interleukin-1 receptor accessory protein-like 1

1

14

Small-scale

0.618

High

616945

IL2RG
Cytokine receptor common subunit gamma

2

18

High-throughput

0.611

High

616951

PMEL
Melanocyte protein PMEL

2

0

High-throughput

0.602

High

616998

I17RD
Interleukin-17 receptor D

2

0

High-throughput

0.602

High

617018

ABCG8
ATP-binding cassette sub-family G member 8

2

0

High-throughput

0.602

High

616952

MATK
Megakaryocyte-associated tyrosine-protein kinase

1

20

Small-scale

0.579

High

616992

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

0

High-throughput

0.546

High

616939

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

16

Small-scale

0.545

High

616949

GRIK1
Glutamate receptor ionotropic, kainate 1

1

4

High-throughput

0.541

High

616957

MTR1A
Melatonin receptor type 1A

1

3

High-throughput

0.541

High

616960

MTR1B
Melatonin receptor type 1B

1

3

High-throughput

0.541

High

616947

IRS1
Insulin receptor substrate 1

1

6

Small-scale

0.536

High

617001

DDX54
ATP-dependent RNA helicase DDX54

1

2

Small-scale

0.536

High

156792

FFAR1
Free fatty acid receptor 1

1

5

High-throughput

0.536

High

175998

GPR37
Prosaposin receptor GPR37

1

5

High-throughput

0.536

High

208447

OX2R
Orexin receptor type 2

1

2

High-throughput

0.536

High

351143

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

1

High-throughput

0.536

High

449192

LEG1
Galectin-1

1

20

High-throughput

0.536

High

600864

TA2R
Thromboxane A2 receptor

1

5

High-throughput

0.536

High

606981

UD11
UDP-glucuronosyltransferase 1A1

1

1

High-throughput

0.536

High

616955

RL28
Large ribosomal subunit protein eL28

1

2

High-throughput

0.536

High

616956

V1BR
Vasopressin V1b receptor

1

3

High-throughput

0.536

High

616973

KCNC3
Potassium voltage-gated channel subfamily C member 3

1

4

High-throughput

0.536

High

616980

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.536

High

616991

T150A
Transmembrane protein 150A

1

1

High-throughput

0.536

High

617006

TR19L
Tumor necrosis factor receptor superfamily member 19L

1

3

High-throughput

0.536

High

617008

MRAP2
Melanocortin-2 receptor accessory protein 2

1

2

High-throughput

0.536

High

617009

OPALI
Opalin

1

1

High-throughput

0.536

High

617027

MARH2
E3 ubiquitin-protein ligase MARCHF2

1

7

High-throughput

0.536

High

617031

I20RA
Interleukin-20 receptor subunit alpha

1

10

High-throughput

0.536

High

617033

PCDB6
Protocadherin beta-6

1

16

High-throughput

0.536

High

617034

PCDB1
Protocadherin beta-1

1

15

High-throughput

0.536

High

617035

PCDG6
Protocadherin gamma-A6

1

17

High-throughput

0.536

High

616958

KCNJ6
G protein-activated inward rectifier potassium channel 2

1

0

High-throughput

0.518

High

616981

AR26L
Putative ankyrin repeat domain-containing protein 26-like protein

1

7

High-throughput

0.514

High

179143

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.513

High

313916

PIGN
GPI ethanolamine phosphate transferase 1

1

0

High-throughput

0.513

High

616978

TM52B
Transmembrane protein 52B

1

0

High-throughput

0.513

High

616985

SO4C1
Solute carrier organic anion transporter family member 4C1

1

0

High-throughput

0.513

High

616989

KCNKI
Potassium channel subfamily K member 18

1

0

High-throughput

0.513

High

616995

MCLN2
Mucolipin-2

1

0

High-throughput

0.513

High

200924

MTSS1
Protein MTSS 1

1

2

Small-scale

0.506

High

266530

GPC4
Glypican-4

1

8

Small-scale

0.501

High

306569

SCEL
Sciellin

1

1

Small-scale

0.501

High

150522

ABLM1
Actin-binding LIM protein 1

1

7

Small-scale

0.489

High

616966

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

1

High-throughput

0.489

High

616986

RHG36
Rho GTPase-activating protein 36

1

2

High-throughput

0.489

High

617000

TPC2
Two pore channel protein 2

1

10

High-throughput

0.489

High

617002

RN133
E3 ubiquitin-protein ligase RNF133

1

8

High-throughput

0.489

High

617016

SE6L1
Seizure 6-like protein

1

5

High-throughput

0.489

High

617019

ZDH11
Palmitoyltransferase ZDHHC11

1

1

High-throughput

0.489

High

617024

CLDN1
Claudin domain-containing protein 1

1

1

High-throughput

0.489

High

521727

CADH1
Cadherin-1

1

20

Small-scale

0.479

High

616974

DSC3
Desmocollin-3

1

20

High-throughput

0.479

High

617015

ACE2
Angiotensin-converting enzyme 2

1

2

Small-scale

0.479

High

616979

PRRT3
Proline-rich transmembrane protein 3

1

2

High-throughput

0.470

High

616968

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.458

High

617003

Q8WW87
SCEL protein

1

1

Small-scale

0.457

High

617005

DDX17
Probable ATP-dependent RNA helicase DDX17

1

1

Small-scale

0.457

High

617014

Q9BXH2
STAT3

1

1

Small-scale

0.457

High

131209

BIN1
Myc box-dependent-interacting protein 1

1

9

High-throughput

0.457

High

239784

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

7

High-throughput

0.445

High

616972

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

8

High-throughput

0.445

High

616975

T132D
Transmembrane protein 132D

1

1

Small-scale

0.439

High

617007

FERM2
Fermitin family homolog 2

1

0

High-throughput

0.438

High

507369

ERG
Transcriptional regulator ERG

1

0

High-throughput

0.282

High

616965

RCAN1
Calcipressin-1

1

0

High-throughput

0.282

High

617004

RSPH1
Radial spoke head 1 homolog

1

0

High-throughput

0.282

High

617028

SLAI2
SLAIN motif-containing protein 2

1

0

Small-scale

0.279

Low

49128

TM223
Transmembrane protein 223

1

0

High-throughput

0.279

Low

50998

PL8L1
PLAC8-like protein 1

1

0

High-throughput

0.279

Low

616941

IL32
Interleukin-32

1

0

High-throughput

0.279

Low

616950

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.279

Low

616982

NIPA3
Magnesium transporter NIPA3

1

0

High-throughput

0.279

Low

616997

SAXO5
Stabilizer of axonemal microtubules 5

1

0

High-throughput

0.279

Low

617017

STMN4
Stathmin-4

1

0

High-throughput

0.279

Low

617029

COPG2
Coatomer subunit gamma-2

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024