Protein: PGES2
Prostaglandin E synthase 2 (EC 5.3.99.3) (Membrane-associated prostaglandin E synthase-2) (mPGE synthase-2) (Microsomal prostaglandin E synthase 2) (mPGES-2) (Prostaglandin-H(2) E-isomerase) [Cleaved into: Prostaglandin E synthase 2 truncated form]

Gene: PGES2, PTGES2
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q9H7Z7

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0003677 - DNA binding
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1165248

SHSA2
Protein shisa-2 homolog

3

1

High-throughput

0.609

High

159508

QCR8
Cytochrome b-c1 complex subunit 8

2

0

High-throughput

0.602

High

1230251

EID3
EP300-interacting inhibitor of differentiation 3

2

0

High-throughput

0.585

High

1333265

PGES2
Prostaglandin E synthase 2

1

0

Small-scale

0.546

High

510039

ERR1
Steroid hormone receptor ERR1

1

1

High-throughput

0.536

High

610922

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

1

High-throughput

0.536

High

682392

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

1

High-throughput

0.536

High

429127

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.518

High

821893

HSP13
Heat shock 70 kDa protein 13

1

0

High-throughput

0.518

High

147668

COX7R
Cytochrome c oxidase subunit 7A-related protein, mitochondrial

1

0

High-throughput

0.513

High

156740

OPLA
5-oxoprolinase

1

0

High-throughput

0.513

High

230170

MGRN1
E3 ubiquitin-protein ligase MGRN1

1

0

High-throughput

0.513

High

236455

RNBP6
Ran-binding protein 6

1

0

High-throughput

0.513

High

263960

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.513

High

296345

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.513

High

316508

MET18
Histidine protein methyltransferase 1 homolog

1

0

High-throughput

0.513

High

333466

CYB
Cytochrome b

1

0

High-throughput

0.513

High

347908

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.513

High

352254

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.513

High

441151

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.513

High

555649

H2AX
Histone H2AX

1

0

High-throughput

0.513

High

598526

NF1
Neurofibromin

1

0

High-throughput

0.513

High

796030

MAGA8
Melanoma-associated antigen 8

1

0

High-throughput

0.513

High

815443

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.513

High

864262

CCHL
Holocytochrome c-type synthase

1

0

High-throughput

0.513

High

992710

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

0

High-throughput

0.513

High

1065786

MLC1
Membrane protein MLC1

1

0

High-throughput

0.513

High

1134945

SYT6
Synaptotagmin-6

1

0

High-throughput

0.513

High

1219003

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1251238

WDR48
WD repeat-containing protein 48

1

0

High-throughput

0.513

High

1284448

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

High-throughput

0.513

High

1299994

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.513

High

1312997

PDC10
Programmed cell death protein 10

1

0

High-throughput

0.513

High

1333267

CHM1A
Charged multivesicular body protein 1a

1

0

High-throughput

0.513

High

1333274

SBDS
Ribosome maturation protein SBDS

1

0

High-throughput

0.513

High

1333275

STK24
Serine/threonine-protein kinase 24

1

0

High-throughput

0.513

High

791986

HD
Huntingtin

1

0

High-throughput

0.493

High

49227

SHSA3
Protein shisa-3 homolog

1

1

High-throughput

0.489

High

966481

EXOSX
Exosome complex component 10

1

0

High-throughput

0.486

High

241639

H2B1K
Histone H2B type 1-K

1

2

High-throughput

0.479

High

918695

H2B1C
Histone H2B type 1-C/E/F/G/I

1

2

High-throughput

0.479

High

935246

H31
Histone H3.1

1

1

High-throughput

0.479

High

1174657

H32
Histone H3.2

1

1

High-throughput

0.479

High

1269630

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1282962

H2B1A
Histone H2B type 1-A

1

2

High-throughput

0.479

High

130599

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

155449

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

258527

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

274632

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.458

High

360420

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

532614

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

553727

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

652264

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

882575

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

917933

H4
Histone H4

1

0

High-throughput

0.458

High

1035594

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1067142

BRD3
Bromodomain-containing protein 3

1

0

High-throughput

0.458

High

1081406

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1148786

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1244701

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1318565

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

1333266

SFXN1
Sideroflexin-1

1

0

High-throughput

0.458

High

1333268

BIRC6
Baculoviral IAP repeat-containing protein 6

1

0

Small-scale

0.458

High

1333271

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1333272

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

Small-scale

0.458

High

1333273

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

1311679

FUZZY
Protein fuzzy homolog

1

1

High-throughput

0.437

High

92557

E9PK12
Fuzzy planar cell polarity protein

1

1

High-throughput

0.407

High

1333270

ABCF2
ATP-binding cassette sub-family F member 2

2

0

High-throughput

0.328

High

900004

VA0D1
V-type proton ATPase subunit d 1

2

0

High-throughput

0.318

High

946065

DLK1
Protein delta homolog 1

2

0

High-throughput

0.318

High

1138425

CP141
Cilia- and flagella-associated protein 141

1

0

High-throughput

0.299

High

276950

ATRN
Attractin

1

0

High-throughput

0.279

Low

542554

QCR7
Cytochrome b-c1 complex subunit 7

1

0

High-throughput

0.279

Low

1012543

TM267
Transmembrane protein 267

1

0

High-throughput

0.279

Low

1030873

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

1149532

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.279

Low

1223309

CPNE9
Copine-9

1

0

High-throughput

0.279

Low

1239991

SUMF1
Formylglycine-generating enzyme

1

0

High-throughput

0.279

Low

1295758

BT3L4
Transcription factor BTF3 homolog 4

1

0

High-throughput

0.279

Low

1333269

QCR9
Cytochrome b-c1 complex subunit 9

1

0

High-throughput

0.279

Low

1171737

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1236994

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024