Protein: MTMR4
Myotubularin-related protein 4 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 2) (FYVE-DSP2) (Zinc finger FYVE domain-containing protein 11)

Gene: MTMR4
Organism: Homo sapiens
Interactions: 159
UniProt ID: Q9NYA4

Gene Ontology (top 5):
GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005615 - extracellular space
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1040957

MTMR3
Myotubularin-related protein 3

5

18

Small-scale

0.919

High

1348337

MTMR4
Myotubularin-related protein 4

2

17

High-throughput

0.754

High

683757

1433B
14-3-3 protein beta/alpha

6

20

High-throughput

0.729

High

1120336

CEP55
Centrosomal protein of 55 kDa

5

1

High-throughput

0.714

High

905178

1433G
14-3-3 protein gamma

5

20

High-throughput

0.712

High

982548

1433F
14-3-3 protein eta

5

20

High-throughput

0.706

High

160810

AURKA
Aurora kinase A

4

5

High-throughput

0.694

High

1220485

DJC10
DnaJ homolog subfamily C member 10

4

2

High-throughput

0.694

High

647323

1433T
14-3-3 protein theta

4

20

High-throughput

0.683

High

1255707

RBCC1
RB1-inducible coiled-coil protein 1

3

10

High-throughput

0.656

High

927584

1433Z
14-3-3 protein zeta/delta

3

20

High-throughput

0.640

High

161883

ZN263
Zinc finger protein 263

2

2

High-throughput

0.628

High

456366

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

2

1

High-throughput

0.628

High

1202471

HOOK3
Protein Hook homolog 3

2

9

High-throughput

0.628

High

1254084

RHPN1
Rhophilin-1

2

8

High-throughput

0.628

High

1348347

MTMR7
Myotubularin-related protein 7

1

17

High-throughput

0.618

High

830487

KC1E
Casein kinase I isoform epsilon

2

3

High-throughput

0.611

High

1088453

CDO1
Cysteine dioxygenase type 1

2

0

High-throughput

0.602

High

1285891

ZN669
Zinc finger protein 669

2

0

High-throughput

0.602

High

1293309

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.602

High

1294622

ZN414
Zinc finger protein 414

2

0

High-throughput

0.602

High

1297522

ZSC31
Zinc finger and SCAN domain-containing protein 31

2

0

High-throughput

0.602

High

1334217

ZN408
Zinc finger protein 408

2

0

High-throughput

0.602

High

1078687

SMAD2
Mothers against decapentaplegic homolog 2

2

9

Small-scale

0.601

High

1133603

ZN684
Zinc finger protein 684

2

0

High-throughput

0.585

High

861946

PLK1
Serine/threonine-protein kinase PLK1

2

7

High-throughput

0.584

High

910087

1433E
14-3-3 protein epsilon

2

6

High-throughput

0.584

High

1287511

AP2M1
AP-2 complex subunit mu

2

3

High-throughput

0.584

High

1312769

MED18
Mediator of RNA polymerase II transcription subunit 18

2

1

High-throughput

0.574

High

808296

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

3

Small-scale

0.561

High

1173775

ACD11
Acyl-CoA dehydrogenase family member 11

2

0

High-throughput

0.559

High

253211

HSF2B
Heat shock factor 2-binding protein

1

1

High-throughput

0.536

High

312973

SLU7
Pre-mRNA-splicing factor SLU7

1

1

High-throughput

0.536

High

485412

GLI4
Zinc finger protein GLI4

1

1

High-throughput

0.536

High

606852

IL10
Interleukin-10

1

1

High-throughput

0.536

High

639102

S100P
Protein S100-P

1

7

High-throughput

0.536

High

924422

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

2

High-throughput

0.536

High

1230650

SIX5
Homeobox protein SIX5

1

1

High-throughput

0.536

High

1263676

MADD
MAP kinase-activating death domain protein

1

9

High-throughput

0.536

High

1312002

DIDO1
Death-inducer obliterator 1

1

2

High-throughput

0.536

High

1314489

IFT27
Intraflagellar transport protein 27 homolog

1

15

High-throughput

0.536

High

1346149

ABCF3
ATP-binding cassette sub-family F member 3

1

1

High-throughput

0.536

High

1347545

ASB6
Ankyrin repeat and SOCS box protein 6

1

4

High-throughput

0.536

High

1348339

GTSE1
G2 and S phase-expressed protein 1

1

1

High-throughput

0.536

High

950306

SMAD3
Mothers against decapentaplegic homolog 3

1

9

Small-scale

0.515

High

49260

FEZF1
Fez family zinc finger protein 1

1

0

High-throughput

0.513

High

213174

SNG1
Synaptogyrin-1

1

0

High-throughput

0.513

High

213750

ENSA
Alpha-endosulfine

1

0

High-throughput

0.513

High

489466

BCL2
Apoptosis regulator Bcl-2

1

0

High-throughput

0.513

High

886943

T2R31
Taste receptor type 2 member 31

1

0

High-throughput

0.513

High

1079170

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.513

High

1160609

TM154
Transmembrane protein 154

1

0

High-throughput

0.513

High

1288717

RM38
Large ribosomal subunit protein mL38

1

0

High-throughput

0.513

High

1298967

BIRC8
Baculoviral IAP repeat-containing protein 8

1

0

High-throughput

0.513

High

1300068

TRNT1
CCA tRNA nucleotidyltransferase 1, mitochondrial

1

0

High-throughput

0.513

High

1348343

SALL4
Sal-like protein 4

1

0

High-throughput

0.513

High

1348344

CAPS1
Calcium-dependent secretion activator 1

1

0

High-throughput

0.513

High

1348345

PADI4
Protein-arginine deiminase type-4

1

0

High-throughput

0.513

High

1348346

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

0

High-throughput

0.513

High

1330491

HIPK3
Homeodomain-interacting protein kinase 3

1

4

High-throughput

0.508

High

1297086

VATG3
V-type proton ATPase subunit G 3

1

0

High-throughput

0.493

High

661467

S10A2
Protein S100-A2

1

7

High-throughput

0.489

High

1273147

FOXJ1
Forkhead box protein J1

1

2

High-throughput

0.489

High

1297898

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

1

1

High-throughput

0.489

High

149363

CTRO
Citron Rho-interacting kinase

1

4

High-throughput

0.479

High

216596

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

1

High-throughput

0.479

High

256108

OBSL1
Obscurin-like protein 1

1

4

High-throughput

0.479

High

302217

AP2A2
AP-2 complex subunit alpha-2

1

4

High-throughput

0.479

High

305657

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.479

High

311635

SMC2
Structural maintenance of chromosomes protein 2

1

2

High-throughput

0.479

High

321656

AP2A1
AP-2 complex subunit alpha-1

1

4

High-throughput

0.479

High

643919

SYVC
Valine--tRNA ligase

1

2

High-throughput

0.479

High

658444

DPOD1
DNA polymerase delta catalytic subunit

1

1

High-throughput

0.479

High

669206

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

10

High-throughput

0.479

High

674981

PUR8
Adenylosuccinate lyase

1

1

High-throughput

0.479

High

684355

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

784104

KPCI
Protein kinase C iota type

1

2

High-throughput

0.479

High

822178

KC1A
Casein kinase I isoform alpha

1

5

High-throughput

0.479

High

822391

KC1D
Casein kinase I isoform delta

1

3

High-throughput

0.479

High

855565

MSH6
DNA mismatch repair protein Msh6

1

1

High-throughput

0.479

High

893495

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.479

High

894819

RAB8A
Ras-related protein Rab-8A

1

6

High-throughput

0.479

High

914405

RB11A
Ras-related protein Rab-11A

1

8

High-throughput

0.479

High

926026

AP2B1
AP-2 complex subunit beta

1

5

High-throughput

0.479

High

946323

BASP1
Brain acid soluble protein 1

1

2

High-throughput

0.479

High

952884

FOXK1
Forkhead box protein K1

1

2

High-throughput

0.479

High

1014093

AP1B1
AP-1 complex subunit beta-1

1

4

High-throughput

0.479

High

1036948

SQSTM
Sequestosome-1

1

4

High-throughput

0.479

High

1041482

CUL2
Cullin-2

1

9

High-throughput

0.479

High

1042682

CUL3
Cullin-3

1

9

High-throughput

0.479

High

1049163

TRI14
Tripartite motif-containing protein 14

1

6

High-throughput

0.479

High

1088078

DUS7
Dual specificity protein phosphatase 7

1

2

High-throughput

0.479

High

1101547

KIF7
Kinesin-like protein KIF7

1

2

High-throughput

0.479

High

1158655

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

4

High-throughput

0.479

High

1199698

ZN598
E3 ubiquitin-protein ligase ZNF598

1

2

High-throughput

0.479

High

1236909

KC1AL
Casein kinase I isoform alpha-like

1

5

High-throughput

0.479

High

1243237

ZN548
Zinc finger protein 548

1

1

High-throughput

0.479

High

1246047

NEDD1
Protein NEDD1

1

4

High-throughput

0.479

High

1252324

GOGA5
Golgin subfamily A member 5

1

7

High-throughput

0.479

High

1283649

EXOC4
Exocyst complex component 4

1

1

High-throughput

0.479

High

1287411

OPTN
Optineurin

1

8

High-throughput

0.479

High

1306325

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

4

High-throughput

0.479

High

1326183

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

14

High-throughput

0.479

High

1334476

ELP3
Elongator complex protein 3

1

1

High-throughput

0.479

High

1342199

WDR6
tRNA

1

8

High-throughput

0.479

High

1345717

SMC4
Structural maintenance of chromosomes protein 4

1

3

High-throughput

0.479

High

1348341

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.479

High

1348349

PKP3
Plakophilin-3

1

4

High-throughput

0.479

High

1348350

IRS2
Insulin receptor substrate 2

1

2

High-throughput

0.479

High

1348351

SNX8
Sorting nexin-8

1

14

High-throughput

0.479

High

1310915

ERP44
Endoplasmic reticulum resident protein 44

1

3

High-throughput

0.470

High

154252

CHK1
Serine/threonine-protein kinase Chk1

1

0

High-throughput

0.458

High

267318

HSBP1
Heat shock factor-binding protein 1

1

0

High-throughput

0.458

High

422640

GPX1
Glutathione peroxidase 1

1

0

High-throughput

0.458

High

659070

MK01
Mitogen-activated protein kinase 1

1

0

High-throughput

0.458

High

708787

MCM5
DNA replication licensing factor MCM5

1

0

High-throughput

0.458

High

789357

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.458

High

1025080

REST
RE1-silencing transcription factor

1

0

High-throughput

0.458

High

1036493

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

0

High-throughput

0.458

High

1088113

UPP1
Uridine phosphorylase 1

1

0

High-throughput

0.458

High

1152397

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.458

High

1204413

CNDG2
Condensin-2 complex subunit G2

1

0

High-throughput

0.458

High

1259875

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

0

High-throughput

0.458

High

1266701

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1293829

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

0

High-throughput

0.458

High

1334640

KT3K
Ketosamine-3-kinase

1

0

High-throughput

0.458

High

1345410

LANC2
LanC-like protein 2

1

0

High-throughput

0.458

High

1348342

DIP2B
Disco-interacting protein 2 homolog B

1

0

High-throughput

0.458

High

989153

FMR1
Fragile X messenger ribonucleoprotein 1

1

4

High-throughput

0.457

High

374987

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.445

High

215491

SCO2
Protein SCO2 homolog, mitochondrial

1

4

High-throughput

0.437

High

964270

FOXK2
Forkhead box protein K2

1

2

High-throughput

0.437

High

992324

DPOE1
DNA polymerase epsilon catalytic subunit A

1

1

High-throughput

0.437

High

1029950

TIF1B
Transcription intermediary factor 1-beta

1

7

High-throughput

0.437

High

1038184

ATR
Serine/threonine-protein kinase ATR

1

5

High-throughput

0.437

High

1220302

DHX40
Probable ATP-dependent RNA helicase DHX40

1

3

High-throughput

0.437

High

1346629

ATD3A
ATPase family AAA domain-containing protein 3A

1

4

High-throughput

0.437

High

1133607

Q5T5D8
Zinc finger protein 684

1

2

High-throughput

0.407

High

147119

NEMP1
Nuclear envelope integral membrane protein 1

1

0

High-throughput

0.279

Low

181123

INSI1
Insulin-induced gene 1 protein

1

0

High-throughput

0.279

Low

245212

RAMP1
Receptor activity-modifying protein 1

1

0

High-throughput

0.279

Low

264243

CDC45
Cell division control protein 45 homolog

1

0

High-throughput

0.279

Low

1053831

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.279

Low

1161698

IN80C
INO80 complex subunit C

1

0

High-throughput

0.279

Low

1217250

CCD71
Coiled-coil domain-containing protein 71

1

0

High-throughput

0.279

Low

1222418

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

0

High-throughput

0.279

Low

1259458

NET5
Netrin-5

1

0

High-throughput

0.279

Low

1348340

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

0

High-throughput

0.279

Low

159407

PLD2
Phospholipase D2

1

0

High-throughput

0.249

Low

778045

RFC3
Replication factor C subunit 3

1

0

High-throughput

0.249

Low

880364

DPOE2
DNA polymerase epsilon subunit 2

1

0

High-throughput

0.249

Low

1205332

PTH
Peptidyl-tRNA hydrolase

1

0

High-throughput

0.249

Low

1229917

PUSL1
tRNA pseudouridine synthase-like 1

1

0

High-throughput

0.249

Low

1282863

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.249

Low

1347582

TM160
Transmembrane protein 160

1

0

High-throughput

0.249

Low

1348338

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

0

High-throughput

0.249

Low

1348348

PDIP2
Polymerase delta-interacting protein 2

1

0

High-throughput

0.249

Low

1241650

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024