Protein: CD70
CD70 antigen (CD27 ligand) (CD27-L) (Tumor necrosis factor ligand superfamily member 7) (CD antigen CD70)

Gene: CD70
Organism: Homo sapiens
Interactions: 164
UniProt ID: P32970

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0002456 - T cell mediated immunity
GO:0005102 - signaling receptor binding
GO:0005125 - cytokine activity
GO:0005164 - tumor necrosis factor receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

645788

CD27
CD27 antigen

4

1

Small-scale

0.895

High

156693

TR13B
Tumor necrosis factor receptor superfamily member 13B

2

0

High-throughput

0.770

High

702212

TNR17
Tumor necrosis factor receptor superfamily member 17

2

0

High-throughput

0.770

High

121448

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

1

High-throughput

0.691

High

702200

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

0

High-throughput

0.656

High

702313

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.656

High

490086

COT1
COUP transcription factor 1

2

2

High-throughput

0.628

High

702201

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

2

1

High-throughput

0.628

High

702220

ATM
Serine-protein kinase ATM

2

1

High-throughput

0.628

High

702226

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

2

1

High-throughput

0.628

High

702258

ZNT5
Proton-coupled zinc antiporter SLC30A5

2

1

High-throughput

0.628

High

168343

SCAM1
Secretory carrier-associated membrane protein 1

2

0

High-throughput

0.602

High

174366

FANCG
Fanconi anemia group G protein

2

0

High-throughput

0.602

High

179149

COPT1
High affinity copper uptake protein 1

2

0

High-throughput

0.602

High

200732

ADCY6
Adenylate cyclase type 6

2

0

High-throughput

0.602

High

255291

HIP1R
Huntingtin-interacting protein 1-related protein

2

0

High-throughput

0.602

High

273552

UTP20
Small subunit processome component 20 homolog

2

0

High-throughput

0.602

High

686154

GLPK
Glycerol kinase

2

0

High-throughput

0.602

High

702228

TBB8
Tubulin beta-8 chain

2

0

High-throughput

0.602

High

702256

MIGA1
Mitoguardin 1

2

0

High-throughput

0.602

High

702259

EXOC6
Exocyst complex component 6

2

0

High-throughput

0.602

High

702261

SPP2B
Signal peptide peptidase-like 2B

2

0

High-throughput

0.602

High

702271

GLMN
Glomulin

2

0

High-throughput

0.602

High

702276

COQ8B
Atypical kinase COQ8B, mitochondrial

2

0

High-throughput

0.602

High

702293

TTYH3
Protein tweety homolog 3

2

0

High-throughput

0.602

High

702312

GPC5B
G-protein coupled receptor family C group 5 member B

2

0

High-throughput

0.602

High

702324

PLAP
Phospholipase A-2-activating protein

2

0

High-throughput

0.602

High

236406

RNBP6
Ran-binding protein 6

2

1

High-throughput

0.574

High

622766

COT2
COUP transcription factor 2

2

2

High-throughput

0.574

High

702198

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

2

1

High-throughput

0.574

High

702202

NR2C2
Nuclear receptor subfamily 2 group C member 2

2

2

High-throughput

0.574

High

702264

RUFY2
RUN and FYVE domain-containing protein 2

2

1

High-throughput

0.574

High

702272

FAKD4
FAST kinase domain-containing protein 4

2

1

High-throughput

0.574

High

702274

TBC20
TBC1 domain family member 20

2

1

High-throughput

0.574

High

702283

RUFY1
RUN and FYVE domain-containing protein 1

2

1

High-throughput

0.574

High

702292

XPO4
Exportin-4

2

2

High-throughput

0.574

High

702301

EI2BG
Translation initiation factor eIF2B subunit gamma

2

1

High-throughput

0.574

High

702302

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

2

1

High-throughput

0.574

High

702305

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

2

1

High-throughput

0.574

High

702317

IPO11
Importin-11

2

2

High-throughput

0.574

High

702318

XPO7
Exportin-7

2

4

High-throughput

0.574

High

702326

TNPO3
Transportin-3

2

3

High-throughput

0.574

High

702204

DYN2
Dynamin-2

1

1

High-throughput

0.536

High

702207

XPO2
Exportin-2

1

2

High-throughput

0.536

High

702214

DYN1
Dynamin-1

1

1

High-throughput

0.536

High

702222

CKAP5
Cytoskeleton-associated protein 5

1

1

High-throughput

0.536

High

217142

EXTL3
Exostosin-like 3

1

0

High-throughput

0.513

High

234326

GSDME
Gasdermin-E

1

0

High-throughput

0.513

High

295713

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

0

High-throughput

0.513

High

676516

CTR1
High affinity cationic amino acid transporter 1

1

0

High-throughput

0.513

High

702205

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

0

High-throughput

0.513

High

702208

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.513

High

702215

PCDH1
Protocadherin-1

1

0

High-throughput

0.513

High

702223

DAG1
Dystroglycan 1

1

0

High-throughput

0.513

High

702260

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.513

High

702266

ELYS
Protein ELYS

1

0

High-throughput

0.513

High

702278

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.513

High

702281

EXOC2
Exocyst complex component 2

1

0

High-throughput

0.513

High

702285

SORT
Sortilin

1

0

High-throughput

0.513

High

702286

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

0

High-throughput

0.513

High

702306

CC50A
Cell cycle control protein 50A

1

0

High-throughput

0.513

High

702310

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

0

High-throughput

0.513

High

702314

ATX10
Ataxin-10

1

0

High-throughput

0.513

High

702321

MINP1
Multiple inositol polyphosphate phosphatase 1

1

0

High-throughput

0.513

High

702322

EXOC7
Exocyst complex component 7

1

0

High-throughput

0.513

High

155540

TNPO2
Transportin-2

1

2

High-throughput

0.489

High

207898

XPOT
Exportin-T

1

3

High-throughput

0.489

High

702203

EI2BB
Translation initiation factor eIF2B subunit beta

1

1

High-throughput

0.489

High

702219

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

1

High-throughput

0.489

High

702221

ATR
Serine/threonine-protein kinase ATR

1

1

High-throughput

0.489

High

702229

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

1

High-throughput

0.489

High

702241

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

1

High-throughput

0.489

High

702300

XPO5
Exportin-5

1

4

High-throughput

0.489

High

702316

EI2BD
Translation initiation factor eIF2B subunit delta

1

1

High-throughput

0.489

High

167850

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

205097

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

702253

S15A4
Solute carrier family 15 member 4

1

0

Small-scale

0.426

High

63298

MET15
12S rRNA N4-methylcytidine

2

0

High-throughput

0.328

High

129116

IFRD1
Interferon-related developmental regulator 1

2

0

High-throughput

0.328

High

195888

TTI1
TELO2-interacting protein 1 homolog

2

0

High-throughput

0.328

High

217232

ORC5
Origin recognition complex subunit 5

2

0

High-throughput

0.328

High

245881

HUS1
Checkpoint protein HUS1

2

0

High-throughput

0.328

High

702206

NUP98
Nuclear pore complex protein Nup98-Nup96

2

0

High-throughput

0.328

High

702218

NU160
Nuclear pore complex protein Nup160

2

0

High-throughput

0.328

High

702224

UBE4A
Ubiquitin conjugation factor E4 A

2

0

High-throughput

0.328

High

702233

SYAM
Alanine--tRNA ligase, mitochondrial

2

0

High-throughput

0.328

High

702234

DEP1A
DEP domain-containing protein 1A

2

0

High-throughput

0.328

High

702235

INT3
Integrator complex subunit 3

2

0

High-throughput

0.328

High

702236

ATLA3
Atlastin-3

2

0

High-throughput

0.328

High

702238

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

2

0

High-throughput

0.328

High

702239

INT5
Integrator complex subunit 5

2

0

High-throughput

0.328

High

702243

DYM
Dymeclin

2

0

High-throughput

0.328

High

702244

HEAT3
HEAT repeat-containing protein 3

2

0

High-throughput

0.328

High

702245

NOP9
Nucleolar protein 9

2

0

High-throughput

0.328

High

702249

RBFA
Putative ribosome-binding factor A, mitochondrial

2

0

High-throughput

0.328

High

702251

KDM8
Bifunctional peptidase and arginyl-hydroxylase JMJD5

2

0

High-throughput

0.328

High

702252

STAG2
Cohesin subunit SA-2

2

0

High-throughput

0.328

High

702257

PPTC7
Protein phosphatase PTC7 homolog

2

0

High-throughput

0.328

High

702262

CHPT1
Cholinephosphotransferase 1

2

0

High-throughput

0.328

High

702265

ATRIP
ATR-interacting protein

2

0

High-throughput

0.328

High

702267

S14L1
SEC14-like protein 1

2

0

High-throughput

0.328

High

702273

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

2

0

High-throughput

0.328

High

702279

INT4
Integrator complex subunit 4

2

0

High-throughput

0.328

High

702280

SYNM
Asparaginyl-tRNA synthetase

2

0

High-throughput

0.328

High

702289

NUP85
Nuclear pore complex protein Nup85

2

0

High-throughput

0.328

High

702295

INT2
Integrator complex subunit 2

2

0

High-throughput

0.328

High

702298

TFB2M
Dimethyladenosine transferase 2, mitochondrial

2

0

High-throughput

0.328

High

702299

NOL11
Nucleolar protein 11

2

0

High-throughput

0.328

High

702304

MDN1
Midasin

2

0

High-throughput

0.328

High

702307

GNL3L
Guanine nucleotide-binding protein-like 3-like protein

2

0

High-throughput

0.328

High

702308

UCKL1
Uridine-cytidine kinase-like 1

2

0

High-throughput

0.328

High

702320

TIM
Protein timeless homolog

2

0

High-throughput

0.328

High

702323

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

2

0

High-throughput

0.328

High

702294

ELOV4
Very long chain fatty acid elongase 4

2

0

High-throughput

0.316

High

49270

GXLT2
Glucoside xylosyltransferase 2

1

0

High-throughput

0.279

Low

130028

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.279

Low

163571

BTAF1
TATA-binding protein-associated factor 172

1

0

High-throughput

0.279

Low

282832

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

0

High-throughput

0.279

Low

313060

AGM1
Phosphoacetylglucosamine mutase

1

0

High-throughput

0.279

Low

314957

SGPL1
Sphingosine-1-phosphate lyase 1

1

0

High-throughput

0.279

Low

321274

TBCD8
TBC1 domain family member 8

1

0

High-throughput

0.279

Low

526645

GILT
Gamma-interferon-inducible lysosomal thiol reductase

1

0

High-throughput

0.279

Low

702199

VKGC
Vitamin K-dependent gamma-carboxylase

1

0

High-throughput

0.279

Low

702209

NU107
Nuclear pore complex protein Nup107

1

0

High-throughput

0.279

Low

702213

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

0

High-throughput

0.279

Low

702216

GALT1
Polypeptide N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.279

Low

702217

WASC5
WASH complex subunit 5

1

0

High-throughput

0.279

Low

702225

UBE3C
Ubiquitin-protein ligase E3C

1

0

High-throughput

0.279

Low

702227

D19L1
Protein C-mannosyl-transferase DPY19L1

1

0

High-throughput

0.279

Low

702230

PIGG
GPI ethanolamine phosphate transferase 2

1

0

High-throughput

0.279

Low

702231

MKS3
Meckelin

1

0

High-throughput

0.279

Low

702232

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

0

High-throughput

0.279

Low

702237

DRS7B
Dehydrogenase/reductase SDR family member 7B

1

0

High-throughput

0.279

Low

702240

BRAT1
BRCA1-associated ATM activator 1

1

0

High-throughput

0.279

Low

702242

THADA
tRNA

1

0

High-throughput

0.279

Low

702246

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

0

High-throughput

0.279

Low

702247

DAAF5
Dynein axonemal assembly factor 5

1

0

High-throughput

0.279

Low

702248

ZDH23
Palmitoyltransferase ZDHHC23

1

0

High-throughput

0.279

Low

702250

INT1
Integrator complex subunit 1

1

0

High-throughput

0.279

Low

702254

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.279

Low

702255

EFNMT
eEF1A lysine and N-terminal methyltransferase

1

0

High-throughput

0.279

Low

702263

NU133
Nuclear pore complex protein Nup133

1

0

High-throughput

0.279

Low

702268

S39A7
Zinc transporter SLC39A7

1

0

High-throughput

0.279

Low

702269

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.279

Low

702270

NU205
Nuclear pore complex protein Nup205

1

0

High-throughput

0.279

Low

702275

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.279

Low

702277

SAAL1
Protein SAAL1

1

0

High-throughput

0.279

Low

702282

CP2S1
Cytochrome P450 2S1

1

0

High-throughput

0.279

Low

702284

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.279

Low

702287

DCNL5
DCN1-like protein 5

1

0

High-throughput

0.279

Low

702288

PTSS2
Phosphatidylserine synthase 2

1

0

High-throughput

0.279

Low

702290

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.279

Low

702291

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

0

High-throughput

0.279

Low

702296

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.279

Low

702297

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.279

Low

702303

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.279

Low

702309

TM160
Transmembrane protein 160

1

0

High-throughput

0.279

Low

702315

NCDN
Neurochondrin

1

0

High-throughput

0.279

Low

702319

HERC5
E3 ISG15--protein ligase HERC5

1

0

High-throughput

0.279

Low

702325

TMED5
Transmembrane emp24 domain-containing protein 5

1

0

High-throughput

0.279

Low

702327

TX264
Testis-expressed protein 264

1

0

High-throughput

0.279

Low

702210

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.249

Low

702211

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

702311

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024