Protein: NGN3
Neurogenin-3 (NGN-3) (Class A basic helix-loop-helix protein 7) (bHLHa7) (Protein atonal homolog 5)

Gene: NGN3, NEUROG3
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q9Y4Z2

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1303333

HTF4
Transcription factor 12

7

20

High-throughput

0.972

High

551329

ITF2
Transcription factor 4

4

20

High-throughput

0.902

High

551594

TFE2
Transcription factor E2-alpha

2

20

High-throughput

0.811

High

814916

ID4
DNA-binding protein inhibitor ID-4

2

20

High-throughput

0.811

High

1294221

HES6
Transcription cofactor HES-6

2

19

High-throughput

0.811

High

1186146

BHA15
Class A basic helix-loop-helix protein 15

1

19

High-throughput

0.691

High

295459

RECQ4
ATP-dependent DNA helicase Q4

2

2

High-throughput

0.628

High

603816

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

1

High-throughput

0.628

High

990410

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

2

4

High-throughput

0.628

High

1060657

ZN638
Zinc finger protein 638

2

1

High-throughput

0.628

High

1218115

ARI3B
AT-rich interactive domain-containing protein 3B

2

4

High-throughput

0.628

High

1223401

ZN100
Zinc finger protein 100

2

3

High-throughput

0.628

High

1224816

ASPM
Abnormal spindle-like microcephaly-associated protein

2

7

High-throughput

0.628

High

1239102

ZN579
Zinc finger protein 579

2

2

High-throughput

0.628

High

1294653

ZN496
Zinc finger protein 496

2

4

High-throughput

0.628

High

1303211

RMD3
Regulator of microtubule dynamics protein 3

2

1

High-throughput

0.628

High

1333516

ZN430
Zinc finger protein 430

2

3

High-throughput

0.628

High

944111

PO6F2
POU domain, class 6, transcription factor 2

2

8

High-throughput

0.606

High

131171

ZN593
Zinc finger protein 593

2

0

High-throughput

0.602

High

317797

NET1
Netrin-1

2

0

High-throughput

0.602

High

880073

RRP1
Ribosomal RNA processing protein 1 homolog A

2

0

High-throughput

0.602

High

1188079

SETX
Probable helicase senataxin

2

0

High-throughput

0.602

High

1333452

YYAP1
YY1-associated protein 1

2

0

High-throughput

0.602

High

1347957

TEX10
Testis-expressed protein 10

2

0

High-throughput

0.602

High

1348950

RTEL1
Regulator of telomere elongation helicase 1

2

0

High-throughput

0.602

High

200762

ADCY6
Adenylate cyclase type 6

2

1

High-throughput

0.574

High

1035156

MYO9B
Unconventional myosin-IXb

2

1

High-throughput

0.574

High

1078072

HERC1
Probable E3 ubiquitin-protein ligase HERC1

2

3

High-throughput

0.574

High

1133371

TMTC4
Protein O-mannosyl-transferase TMTC4

2

2

High-throughput

0.574

High

1158155

DHX57
Putative ATP-dependent RNA helicase DHX57

2

1

High-throughput

0.574

High

1284712

EME1
Crossover junction endonuclease EME1

2

1

High-throughput

0.574

High

1297579

RMD2
Regulator of microtubule dynamics protein 2

2

1

High-throughput

0.574

High

1307493

TEP1
Telomerase protein component 1

2

2

High-throughput

0.574

High

981795

REL
Proto-oncogene c-Rel

1

6

High-throughput

0.573

High

603894

RS4Y1
Small ribosomal subunit protein eS4, Y isoform 1

1

1

High-throughput

0.536

High

822405

KC1D
Casein kinase I isoform delta

1

3

High-throughput

0.536

High

974176

DYST
Dystonin

1

7

High-throughput

0.536

High

1058851

LBR
Delta(14)-sterol reductase LBR

1

3

High-throughput

0.536

High

1135241

RBM26
RNA-binding protein 26

1

3

High-throughput

0.536

High

1160997

CTR9
RNA polymerase-associated protein CTR9 homolog

1

3

High-throughput

0.536

High

1170102

SRCAP
Helicase SRCAP

1

10

High-throughput

0.536

High

1224553

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

11

High-throughput

0.536

High

1237171

PAF1
RNA polymerase II-associated factor 1 homolog

1

1

High-throughput

0.536

High

1237598

DDX51
ATP-dependent RNA helicase DDX51

1

1

High-throughput

0.536

High

1259982

PHF10
PHD finger protein 10

1

5

High-throughput

0.536

High

1295684

ZFP91
E3 ubiquitin-protein ligase ZFP91

1

4

High-throughput

0.536

High

1297892

HEXI2
Protein HEXIM2

1

2

High-throughput

0.536

High

1348287

DDX56
Probable ATP-dependent RNA helicase DDX56

1

1

High-throughput

0.536

High

1350465

RBM27
RNA-binding protein 27

1

3

High-throughput

0.536

High

1357496

MAGD2
Melanoma-associated antigen D2

1

3

High-throughput

0.536

High

1357560

FAF1
FAS-associated factor 1

1

1

High-throughput

0.536

High

1377475

ZN281
Zinc finger protein 281

1

3

High-throughput

0.536

High

1377918

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

2

High-throughput

0.536

High

997631

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

1

0

High-throughput

0.513

High

1132189

NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9

1

0

High-throughput

0.513

High

1158354

CDC73
Parafibromin

1

0

High-throughput

0.513

High

1205526

PTOV1
Prostate tumor-overexpressed gene 1 protein

1

0

High-throughput

0.513

High

1257350

HASP
Serine/threonine-protein kinase haspin

1

0

High-throughput

0.513

High

1310083

TIRR
Tudor-interacting repair regulator protein

1

0

High-throughput

0.513

High

1343236

TIGAR
Fructose-2,6-bisphosphatase TIGAR

1

0

High-throughput

0.513

High

1344391

SPHK2
Sphingosine kinase 2

1

0

High-throughput

0.513

High

70720

MYO9A
Unconventional myosin-IXa

1

1

High-throughput

0.489

High

237358

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

1

High-throughput

0.489

High

324911

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

2

High-throughput

0.489

High

344029

ASSY
Argininosuccinate synthase

1

1

High-throughput

0.489

High

1135376

ATD3B
ATPase family AAA domain-containing protein 3B

1

1

High-throughput

0.489

High

1139761

ZMYM4
Zinc finger MYM-type protein 4

1

1

High-throughput

0.489

High

1168020

GGYF2
GRB10-interacting GYF protein 2

1

1

High-throughput

0.489

High

1185051

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

1

High-throughput

0.489

High

1193244

ZER1
Protein zer-1 homolog

1

1

High-throughput

0.489

High

1234120

FBXL6
F-box/LRR-repeat protein 6

1

2

High-throughput

0.489

High

1254593

RS4Y2
Small ribosomal subunit protein eS4, Y isoform 2

1

1

High-throughput

0.489

High

1290912

TRI11
E3 ubiquitin-protein ligase TRIM11

1

3

High-throughput

0.489

High

1308900

DDX50
ATP-dependent RNA helicase DDX50

1

1

High-throughput

0.489

High

1319194

ZY11B
Protein zyg-11 homolog B

1

1

High-throughput

0.489

High

1335741

MRM3
rRNA methyltransferase 3, mitochondrial

1

1

High-throughput

0.489

High

1343085

LUC7L
Putative RNA-binding protein Luc7-like 1

1

2

High-throughput

0.489

High

1377917

TF3C3
General transcription factor 3C polypeptide 3

1

4

High-throughput

0.489

High

649854

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

1132647

CHCH9
Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial

1

2

High-throughput

0.445

High

49281

GXLT2
Glucoside xylosyltransferase 2

2

0

High-throughput

0.328

High

133751

NOP56
Nucleolar protein 56

2

0

High-throughput

0.328

High

1238800

CC71L
Coiled-coil domain-containing protein 71L

2

0

High-throughput

0.328

High

1259931

TF3C2
General transcription factor 3C polypeptide 2

2

0

High-throughput

0.328

High

1260972

DCAF4
DDB1- and CUL4-associated factor 4

2

0

High-throughput

0.328

High

1332154

DHX35
Probable ATP-dependent RNA helicase DHX35

2

0

High-throughput

0.328

High

183398

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

0

High-throughput

0.279

Low

315092

SGPL1
Sphingosine-1-phosphate lyase 1

1

0

High-throughput

0.279

Low

528193

CY24A
Cytochrome b-245 light chain

1

0

High-throughput

0.279

Low

814127

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

0

High-throughput

0.279

Low

822530

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.279

Low

830202

PRI2
DNA primase large subunit

1

0

High-throughput

0.279

Low

1016462

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.279

Low

1045024

MOGS
Mannosyl-oligosaccharide glucosidase

1

0

High-throughput

0.279

Low

1050952

DPYL3
Dihydropyrimidinase-related protein 3

1

0

High-throughput

0.279

Low

1125244

NOM1
Nucleolar MIF4G domain-containing protein 1

1

0

High-throughput

0.279

Low

1221542

PLPL6
Patatin-like phospholipase domain-containing protein 6

1

0

High-throughput

0.279

Low

1241384

HJURP
Holliday junction recognition protein

1

0

High-throughput

0.279

Low

1345591

SLX9
Ribosome biogenesis protein SLX9 homolog

1

0

High-throughput

0.279

Low

1347976

TOR4A
Torsin-4A

1

0

High-throughput

0.279

Low

1354616

ADDG
Gamma-adducin

1

0

High-throughput

0.279

Low

1377901

LAS1L
Ribosomal biogenesis protein LAS1L

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024