Protein: SGMR1
Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding protein) (SR-BP) (Sigma 1-type opioid receptor) (SIG-1R) (Sigma1-receptor) (Sigma1R) (hSigmaR1)

Gene: SGMR1, SIGMAR1
Organism: Homo sapiens
Interactions: 110
UniProt ID: Q99720

Gene Ontology (top 5):
GO:0004985 - G protein-coupled opioid receptor activity
GO:0005635 - nuclear envelope
GO:0005637 - nuclear inner membrane
GO:0005640 - nuclear outer membrane
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1305906

SGMR1
Sigma non-opioid intracellular receptor 1

2

1

Small-scale

0.820

High

1087786

RTN1
Reticulon-1

2

1

High-throughput

0.628

High

1292345

RN185
E3 ubiquitin-protein ligase RNF185

3

0

Small-scale

0.628

High

1224331

AGRG5
Adhesion G-protein coupled receptor G5

2

0

High-throughput

0.602

High

168011

NPC1
NPC intracellular cholesterol transporter 1

2

0

High-throughput

0.585

High

529625

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.547

High

1125519

PDZ11
PDZ domain-containing protein 11

1

1

High-throughput

0.541

High

134401

ACKR2
Atypical chemokine receptor 2

1

5

High-throughput

0.536

High

168200

PLCB
1-acyl-sn-glycerol-3-phosphate acyltransferase beta

1

1

High-throughput

0.536

High

172198

GP182
G-protein coupled receptor 182

1

7

High-throughput

0.536

High

237756

TSN2
Tetraspanin-2

1

2

High-throughput

0.536

High

307100

RTN3
Reticulon-3

1

1

High-throughput

0.536

High

326192

TSN15
Tetraspanin-15

1

1

High-throughput

0.536

High

626580

FPR2
N-formyl peptide receptor 2

1

7

High-throughput

0.536

High

656970

5HT1B
5-hydroxytryptamine receptor 1B

1

2

High-throughput

0.536

High

714688

CNR2
Cannabinoid receptor 2

1

5

Small-scale

0.536

High

895719

CXCR4
C-X-C chemokine receptor type 4

1

6

High-throughput

0.536

High

1305907

CML1
Chemerin-like receptor 1

1

7

High-throughput

0.536

High

1305908

TM208
Transmembrane protein 208

1

1

High-throughput

0.536

High

1305916

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

1

High-throughput

0.536

High

395570

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.530

High

49421

TMM72
Transmembrane protein 72

1

0

High-throughput

0.513

High

118986

KCNK1
Potassium channel subfamily K member 1

1

0

High-throughput

0.513

High

170129

PLS1
Phospholipid scramblase 1

1

0

High-throughput

0.513

High

173511

RER1
Protein RER1

1

0

High-throughput

0.513

High

254189

FZD7
Frizzled-7

1

0

High-throughput

0.513

High

277745

PRAF3
PRA1 family protein 3

1

0

High-throughput

0.513

High

313952

PIGN
GPI ethanolamine phosphate transferase 1

1

0

High-throughput

0.513

High

318523

CDS2
Phosphatidate cytidylyltransferase 2

1

0

High-throughput

0.513

High

392721

B3A2
Anion exchange protein 2

1

0

High-throughput

0.513

High

505463

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

0

High-throughput

0.513

High

622706

ERD21
ER lumen protein-retaining receptor 1

1

0

High-throughput

0.513

High

646280

STOM
Stomatin

1

0

High-throughput

0.513

High

1016667

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.513

High

1030639

CLN3
Battenin

1

0

High-throughput

0.513

High

1072943

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.513

High

1109945

SHSL1
Protein shisa-like-1

1

0

High-throughput

0.513

High

1172979

GOT1A
Vesicle transport protein GOT1A

1

0

High-throughput

0.513

High

1202360

RETR3
Reticulophagy regulator 3

1

0

High-throughput

0.513

High

1218928

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1221313

S35F2
Solute carrier family 35 member F2

1

0

High-throughput

0.513

High

1233027

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

1240098

TM87A
Transmembrane protein 87A

1

0

High-throughput

0.513

High

1253873

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

1301957

SERC2
Serine incorporator 2

1

0

High-throughput

0.513

High

1305909

TMPSD
Transmembrane protease serine 13

1

0

High-throughput

0.513

High

1305912

SG196
Protein O-mannose kinase

1

0

High-throughput

0.513

High

1305913

VEZA
Vezatin

1

0

High-throughput

0.513

High

1305919

GPC5B
G-protein coupled receptor family C group 5 member B

1

0

High-throughput

0.513

High

1305920

GCP4
Gamma-tubulin complex component 4

1

0

High-throughput

0.513

High

1305922

SC6A5
Sodium- and chloride-dependent glycine transporter 2

1

0

High-throughput

0.513

High

1271825

GHSR
Growth hormone secretagogue receptor type 1

1

3

Small-scale

0.504

High

675326

SORCN
Sorcin

1

0

Small-scale

0.494

High

1269064

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

1

0

High-throughput

0.493

High

121010

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.493

High

568779

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.493

High

740049

TGFR2
TGF-beta receptor type-2

1

0

High-throughput

0.493

High

839670

SERPH
Serpin H1

1

0

High-throughput

0.493

High

328377

S1PR4
Sphingosine 1-phosphate receptor 4

1

6

High-throughput

0.489

High

446059

CD63
CD63 antigen

1

1

High-throughput

0.489

High

600829

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

6

High-throughput

0.489

High

626756

NK1R
Substance-P receptor

1

3

High-throughput

0.489

High

664370

AA2BR
Adenosine receptor A2b

1

4

High-throughput

0.489

High

686730

CCR1
C-C chemokine receptor type 1

1

5

High-throughput

0.489

High

723387

APJ
Apelin receptor

1

5

High-throughput

0.489

High

1031059

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

5

High-throughput

0.489

High

1202719

P2RY8
P2Y purinoceptor 8

1

6

High-throughput

0.489

High

1268638

LPAR1
Lysophosphatidic acid receptor 1

1

5

High-throughput

0.489

High

1305915

GPR84
G-protein coupled receptor 84

1

2

High-throughput

0.489

High

1305917

GP173
Probable G-protein coupled receptor 173

1

2

High-throughput

0.489

High

1305921

GPR52
G-protein coupled receptor 52

1

4

High-throughput

0.489

High

1305923

GPR45
Probable G-protein coupled receptor 45

1

3

High-throughput

0.489

High

723092

OPRM
Mu-type opioid receptor

1

4

Small-scale

0.479

High

1018910

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

1

Small-scale

0.479

High

1028150

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

1

Small-scale

0.479

High

1262520

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

1

1

High-throughput

0.479

High

504636

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

561665

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

0

Small-scale

0.458

High

779981

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

942373

DLG4
Disks large homolog 4

1

0

Small-scale

0.458

High

965142

ANK2
Ankyrin-2

1

0

Small-scale

0.458

High

1055781

ITPR3
Inositol 1,4,5-trisphosphate receptor type 3

1

0

Small-scale

0.458

High

1148751

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1165892

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1240272

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.458

High

1259703

RN139
E3 ubiquitin-protein ligase RNF139

1

0

High-throughput

0.458

High

1305525

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.458

High

941355

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

962700

CAC1B
Voltage-dependent N-type calcium channel subunit alpha-1B

1

0

Small-scale

0.292

High

179323

COPT2
Protein SLC31A2

1

0

High-throughput

0.279

Low

299198

CSCL1
CSC1-like protein 1

1

0

High-throughput

0.279

Low

686369

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

0

High-throughput

0.279

Low

1126239

RABL3
Rab-like protein 3

1

0

High-throughput

0.279

Low

1168194

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

1239809

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.279

Low

1264272

BRI3B
BRI3-binding protein

1

0

High-throughput

0.279

Low

1305910

YIPF3
Protein YIPF3

1

0

High-throughput

0.279

Low

1305914

SMDC1
SAYSvFN domain-containing protein 1

1

0

High-throughput

0.279

Low

205886

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

279973

ATP5L
ATP synthase subunit g, mitochondrial

1

0

High-throughput

0.249

Low

553531

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

652063

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

721257

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1017028

KCNH2
Potassium voltage-gated channel subfamily H member 2

1

0

Small-scale

0.249

Low

1156686

TECT3
Tectonic-3

1

0

High-throughput

0.249

Low

1171401

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1252181

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1305911

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1305918

T106B
Transmembrane protein 106B

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024