Protein: NISCH
Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor antisera-selected protein) (hIRAS) (Imidazoline-1 receptor) (I1R) (Imidazoline-1 receptor candidate protein) (I-1 receptor candidate protein) (I1R candidate protein)

Gene: NISCH
Organism: Homo sapiens
Interactions: 151
UniProt ID: Q9Y2I1

Gene Ontology (top 5):
GO:0005178 - integrin binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005769 - early endosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1285847

SGK3
Serine/threonine-protein kinase Sgk3

1

4

High-throughput

0.691

High

655515

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

4

3

High-throughput

0.683

High

896268

UBC12
NEDD8-conjugating enzyme Ubc12

3

2

High-throughput

0.667

High

845813

RAB9A
Ras-related protein Rab-9A

3

15

Small-scale

0.655

High

1034215

U119A
Protein unc-119 homolog A

2

1

High-throughput

0.628

High

1255274

HAVR2
Hepatitis A virus cellular receptor 2

2

1

High-throughput

0.628

High

1267457

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

9

High-throughput

0.628

High

724575

IRS1
Insulin receptor substrate 1

1

7

Small-scale

0.618

High

1331667

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.618

High

1377253

NISCH
Nischarin

1

20

Small-scale

0.618

High

1377256

IRS2
Insulin receptor substrate 2

1

7

Small-scale

0.618

High

151937

IRS4
Insulin receptor substrate 4

2

3

Small-scale

0.611

High

1042877

CUL3
Cullin-3

2

5

High-throughput

0.611

High

1160640

CNKR3
Connector enhancer of kinase suppressor of ras 3

2

0

High-throughput

0.602

High

1327158

SPRTN
DNA-dependent metalloprotease SPRTN

2

0

High-throughput

0.585

High

507327

LAMP1
Lysosome-associated membrane glycoprotein 1

2

6

High-throughput

0.584

High

916087

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

723270

PE2R4
Prostaglandin E2 receptor EP4 subtype

1

6

High-throughput

0.541

High

1298936

CLIC6
Chloride intracellular channel protein 6

1

1

High-throughput

0.541

High

129353

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

11

High-throughput

0.536

High

179283

COPT1
High affinity copper uptake protein 1

1

1

High-throughput

0.536

High

182397

PER1
Period circadian protein homolog 1

1

3

High-throughput

0.536

High

739881

SRP14
Signal recognition particle 14 kDa protein

1

1

High-throughput

0.536

High

782066

RGS2
Regulator of G-protein signaling 2

1

1

High-throughput

0.536

High

906951

PRS4
26S proteasome regulatory subunit 4

1

1

High-throughput

0.536

High

910183

1433E
14-3-3 protein epsilon

1

8

High-throughput

0.536

High

924969

GRB2
Growth factor receptor-bound protein 2

1

8

High-throughput

0.536

High

927680

1433Z
14-3-3 protein zeta/delta

1

19

High-throughput

0.536

High

943174

KC1G2
Casein kinase I isoform gamma-2

1

4

High-throughput

0.536

High

1219126

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

1333650

MANS1
MANSC domain-containing protein 1

1

1

High-throughput

0.536

High

1347495

GID8
Glucose-induced degradation protein 8 homolog

1

1

High-throughput

0.536

High

1357275

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.536

High

1377258

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

1

High-throughput

0.536

High

1051213

BTG3
Protein BTG3

1

0

High-throughput

0.518

High

49915

ODAM
Odontogenic ameloblast-associated protein

1

0

High-throughput

0.513

High

1037566

PNOC
Prepronociceptin [Cleaved into: Nocistatin; Nociceptin

1

0

High-throughput

0.513

High

1272828

FGF11
Fibroblast growth factor 11

1

0

High-throughput

0.513

High

1327721

SHRPN
Sharpin

1

0

High-throughput

0.513

High

175318

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

951828

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.493

High

270844

FOXH1
Forkhead box protein H1

1

5

High-throughput

0.489

High

1229781

ZN444
Zinc finger protein 444

1

4

High-throughput

0.489

High

1293127

ZN764
Zinc finger protein 764

1

5

High-throughput

0.489

High

1294633

ZN414
Zinc finger protein 414

1

1

High-throughput

0.489

High

1313627

ZN747
Zinc finger protein 747

1

5

High-throughput

0.489

High

120723

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

206192

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

279764

FLOT1
Flotillin-1

1

2

High-throughput

0.479

High

318257

DIRA3
GTP-binding protein Di-Ras3

1

6

High-throughput

0.479

High

339167

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.479

High

349018

RASN
GTPase NRas

1

20

High-throughput

0.479

High

350707

RASK
GTPase KRas

1

20

High-throughput

0.479

High

364487

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.479

High

385751

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

411531

INSR
Insulin receptor

1

20

High-throughput

0.479

High

411898

LCK
Tyrosine-protein kinase Lck

1

6

High-throughput

0.479

High

434090

LYN
Tyrosine-protein kinase Lyn

1

6

High-throughput

0.479

High

435807

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.479

High

508279

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

527895

LAMP2
Lysosome-associated membrane glycoprotein 2

1

6

High-throughput

0.479

High

545706

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

564748

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

567337

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

592070

RAB4A
Ras-related protein Rab-4A

1

9

High-throughput

0.479

High

592594

RAB5A
Ras-related protein Rab-5A

1

7

High-throughput

0.479

High

608203

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.479

High

648939

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.479

High

665370

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.479

High

665440

EPHA3
Ephrin type-A receptor 3

1

20

High-throughput

0.479

High

665544

EPHA8
Ephrin type-A receptor 8

1

20

High-throughput

0.479

High

665686

EPHB2
Ephrin type-B receptor 2

1

20

High-throughput

0.479

High

721823

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

829087

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

1

High-throughput

0.479

High

845362

RAB7A
Ras-related protein Rab-7a

1

11

High-throughput

0.479

High

852684

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

870938

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.479

High

872509

EPHA5
Ephrin type-A receptor 5

1

20

High-throughput

0.479

High

872733

EPHA4
Ephrin type-A receptor 4

1

20

High-throughput

0.479

High

882650

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

High-throughput

0.479

High

892689

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

894602

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

895328

RAB2A
Ras-related protein Rab-2A

1

9

High-throughput

0.479

High

901063

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

901277

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

913199

ARF6
ADP-ribosylation factor 6

1

2

High-throughput

0.479

High

914475

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.479

High

925746

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

940608

CXAR
Coxsackievirus and adenovirus receptor

1

4

High-throughput

0.479

High

951470

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

968523

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.479

High

975124

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

1032697

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.479

High

1070466

RAB35
Ras-related protein Rab-35

1

8

High-throughput

0.479

High

1071718

KS6A2
Ribosomal protein S6 kinase alpha-2

1

5

High-throughput

0.479

High

1072633

EPHA7
Ephrin type-A receptor 7

1

20

High-throughput

0.479

High

1076824

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

1081656

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.479

High

1083911

NTRK2
BDNF/NT-3 growth factors receptor

1

20

High-throughput

0.479

High

1084248

OCLN
Occludin

1

1

High-throughput

0.479

High

1108552

PCGF3
Polycomb group RING finger protein 3

1

3

High-throughput

0.479

High

1119524

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

4

High-throughput

0.479

High

1152205

LTOR1
Ragulator complex protein LAMTOR1

1

4

High-throughput

0.479

High

1153760

STYK1
Tyrosine-protein kinase STYK1

1

19

High-throughput

0.479

High

1166087

LMBRL
Protein LMBR1L

1

3

High-throughput

0.479

High

1172338

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

1183052

SND1
Staphylococcal nuclease domain-containing protein 1

1

3

High-throughput

0.479

High

1183619

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1197599

PCGF5
Polycomb group RING finger protein 5

1

2

High-throughput

0.479

High

1230435

CXD3
Gap junction delta-3 protein

1

5

High-throughput

0.479

High

1236585

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

High-throughput

0.479

High

1267280

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1269261

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

1269971

ESR2
Estrogen receptor beta

1

9

High-throughput

0.479

High

1270841

CBP
CREB-binding protein

1

7

High-throughput

0.479

High

1285467

Q96BE0
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

1306903

ARI3A
AT-rich interactive domain-containing protein 3A

1

3

High-throughput

0.479

High

1315173

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

18

High-throughput

0.479

High

1330448

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.479

High

1330998

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1332796

EGLN3
Prolyl hydroxylase EGLN3

1

5

High-throughput

0.479

High

1335404

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1356657

NUP50
Nuclear pore complex protein Nup50

1

3

High-throughput

0.479

High

1357931

LAMP3
Lysosome-associated membrane glycoprotein 3

1

6

High-throughput

0.479

High

1377257

ARI1
E3 ubiquitin-protein ligase ARIH1

1

9

High-throughput

0.479

High

772210

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.460

High

318300

VATG2
V-type proton ATPase subunit G 2

1

0

High-throughput

0.458

High

484399

SCHI1
Schwannomin-interacting protein 1

1

0

High-throughput

0.458

High

840427

ERF
ETS domain-containing transcription factor ERF

1

0

High-throughput

0.458

High

1217463

NUDC3
NudC domain-containing protein 3

1

0

High-throughput

0.458

High

1284277

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

1331209

SENP3
Sentrin-specific protease 3

1

0

Small-scale

0.458

High

1344419

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.458

High

1377255

MARF1
Meiosis regulator and mRNA stability factor 1

1

0

High-throughput

0.458

High

1155938

Q6NSK7
RIN3 protein

1

0

High-throughput

0.438

High

72775

B4DET5
cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121

1

5

High-throughput

0.437

High

118497

HAX1
HCLS1-associated protein X-1

1

2

High-throughput

0.437

High

1283108

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1316266

K1671
Uncharacterized protein KIAA1671

1

1

High-throughput

0.437

High

445960

NMB
Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]

1

0

High-throughput

0.279

Low

610679

IBP4
Insulin-like growth factor-binding protein 4

1

0

High-throughput

0.279

Low

1132425

SPT46
Spermatogenesis-associated protein 46

1

0

High-throughput

0.279

Low

1140465

F219B
Protein FAM219B

1

0

High-throughput

0.279

Low

1221504

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

0

High-throughput

0.279

Low

1281079

LEAP2
Liver-expressed antimicrobial peptide 2

1

0

High-throughput

0.279

Low

1357093

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.279

Low

1377254

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.279

Low

352317

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

1347631

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

0

High-throughput

0.249

Low

1217206

LACC1
Purine nucleoside phosphorylase LACC1

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024