Protein: PRDM6
Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6)

Gene: PRDM6
Organism: Homo sapiens
Interactions: 88
UniProt ID: Q9NQX0

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0010468 - regulation of gene expression
GO:0022008 - neurogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1343879

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

3

17

Small-scale

0.843

High

1326821

PRD14
PR domain zinc finger protein 14

2

19

High-throughput

0.811

High

871485

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

2

1

High-throughput

0.783

High

1089385

LONF1
LON peptidase N-terminal domain and RING finger protein 1

2

16

High-throughput

0.783

High

1335277

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

2

18

High-throughput

0.783

High

1335898

NEK6
Serine/threonine-protein kinase Nek6

2

9

High-throughput

0.783

High

203469

MTG8R
Protein CBFA2T2

5

8

High-throughput

0.716

High

274295

STK16
Serine/threonine-protein kinase 16

2

3

High-throughput

0.700

High

1299521

TSSK3
Testis-specific serine/threonine-protein kinase 3

2

0

High-throughput

0.655

High

209176

NCK2
Cytoplasmic protein NCK2

2

1

High-throughput

0.606

High

274782

RA51D
DNA repair protein RAD51 homolog 4

2

1

High-throughput

0.606

High

324634

BAG3
BAG family molecular chaperone regulator 3

2

2

High-throughput

0.606

High

638409

RBTN2
Rhombotin-2

2

9

High-throughput

0.606

High

638580

RBTN1
Rhombotin-1

2

9

High-throughput

0.606

High

670405

AQP1
Aquaporin-1

2

2

High-throughput

0.606

High

678976

HXC8
Homeobox protein Hox-C8

2

12

High-throughput

0.606

High

874339

GEM
GTP-binding protein GEM

2

2

High-throughput

0.606

High

978246

ARI5A
AT-rich interactive domain-containing protein 5A

2

3

High-throughput

0.606

High

987474

MTG8
Protein CBFA2T1

2

8

High-throughput

0.606

High

993619

TLE5
TLE family member 5

2

3

High-throughput

0.606

High

1046421

PTK6
Protein-tyrosine kinase 6

2

2

High-throughput

0.606

High

1049155

TRI14
Tripartite motif-containing protein 14

2

20

High-throughput

0.606

High

1050810

FHL2
Four and a half LIM domains protein 2

2

19

High-throughput

0.606

High

1144789

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

6

High-throughput

0.606

High

1148035

ZFY26
Zinc finger FYVE domain-containing protein 26

2

3

High-throughput

0.606

High

1246569

IKBD
NF-kappa-B inhibitor delta

2

1

High-throughput

0.606

High

1254511

CCHCR
Coiled-coil alpha-helical rod protein 1

2

8

High-throughput

0.606

High

1262204

TEKT4
Tektin-4

2

1

High-throughput

0.606

High

1273506

KAT5
Histone acetyltransferase KAT5

2

1

High-throughput

0.606

High

1331868

BAFL
Barrier-to-autointegration factor-like protein

2

1

High-throughput

0.606

High

1335775

CBX8
Chromobox protein homolog 8

2

20

High-throughput

0.606

High

1343582

EXOS5
Exosome complex component RRP46

2

1

High-throughput

0.606

High

1343880

FX4L1
Forkhead box protein D4-like 1

2

2

High-throughput

0.606

High

1343881

AIRIM
AFG2-interacting ribosome maturation factor

2

1

High-throughput

0.606

High

1343882

ABI2
Abl interactor 2

2

2

High-throughput

0.606

High

50461

SYCE3
Synaptonemal complex central element protein 3

2

0

High-throughput

0.602

High

495763

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

2

0

High-throughput

0.580

High

1184793

ATOSB
Atos homolog protein B

2

0

High-throughput

0.580

High

1318826

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

2

0

High-throughput

0.580

High

1334806

ROP1A
Ropporin-1A

2

0

High-throughput

0.580

High

1343883

CCNL1
Cyclin-L1

2

0

High-throughput

0.580

High

327112

GPAN1
G patch domain and ankyrin repeat-containing protein 1

2

1

High-throughput

0.553

High

703443

CSTF2
Cleavage stimulation factor subunit 2

2

1

High-throughput

0.553

High

883391

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

1

High-throughput

0.553

High

1047713

IL16
Pro-interleukin-16 [Cleaved into: Interleukin-16

2

4

High-throughput

0.553

High

1052027

ELOA1
Elongin-A

2

3

High-throughput

0.553

High

1102805

CCD57
Coiled-coil domain-containing protein 57

2

8

High-throughput

0.553

High

1174117

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

2

1

High-throughput

0.553

High

1234827

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

2

2

High-throughput

0.553

High

1238531

BANP
Protein BANP

2

1

High-throughput

0.553

High

1313790

KIFC3
Kinesin-like protein KIFC3

2

5

High-throughput

0.553

High

1318459

TSG10
Testis-specific gene 10 protein

2

12

High-throughput

0.553

High

1327828

ENKD1
Enkurin domain-containing protein 1

2

1

High-throughput

0.553

High

1343885

TCAF1
TRPM8 channel-associated factor 1

2

1

High-throughput

0.553

High

254010

MTG16
Protein CBFA2T3

1

8

High-throughput

0.536

High

551290

ITF2
Transcription factor 4

1

1

High-throughput

0.536

High

177388

HDAC3
Histone deacetylase 3

1

14

Small-scale

0.479

High

882162

GSC
Homeobox protein goosecoid

1

3

High-throughput

0.479

High

935273

H31
Histone H3.1

1

19

Small-scale

0.479

High

949895

CBX1
Chromobox protein homolog 1

1

20

Small-scale

0.479

High

999124

EP300
Histone acetyltransferase p300

1

10

Small-scale

0.479

High

1038741

HDAC1
Histone deacetylase 1

1

14

Small-scale

0.479

High

1042612

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1270460

HDAC2
Histone deacetylase 2

1

14

Small-scale

0.479

High

1334132

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

5

Small-scale

0.479

High

1115820

Q49AR9
ANKS1A protein

1

3

High-throughput

0.470

High

1268508

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

3

High-throughput

0.439

High

972590

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

1

High-throughput

0.437

High

68499

GRCR1
Glutaredoxin domain-containing cysteine-rich protein 1

2

0

High-throughput

0.316

High

207381

FRS3
Fibroblast growth factor receptor substrate 3

2

0

High-throughput

0.316

High

216593

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

2

0

High-throughput

0.316

High

599316

AGT1
Alanine--glyoxylate aminotransferase

2

0

High-throughput

0.316

High

814543

SYQ
Glutamine--tRNA ligase

2

0

High-throughput

0.316

High

1110215

T10IP
Testis-specific protein 10-interacting protein

2

0

High-throughput

0.316

High

1121368

TYW2
tRNA wybutosine-synthesizing protein 2 homolog

2

0

High-throughput

0.316

High

1140026

TTC23
Tetratricopeptide repeat protein 23

2

0

High-throughput

0.316

High

1183903

KCTD9
BTB/POZ domain-containing protein KCTD9

2

0

High-throughput

0.316

High

1205629

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

1223825

CE57L
Centrosomal protein CEP57L1

2

0

High-throughput

0.316

High

1238836

IQUB
IQ motif and ubiquitin-like domain-containing protein

2

0

High-throughput

0.316

High

1251184

G45IP
Large ribosomal subunit protein mL64

2

0

High-throughput

0.316

High

1254740

MYOZ3
Myozenin-3

2

0

High-throughput

0.316

High

1262334

PIHD2
PIH1 domain-containing protein 2

2

0

High-throughput

0.316

High

1293360

CC120
Coiled-coil domain-containing protein 120

2

0

High-throughput

0.316

High

1343884

SMAG1
Protein Smaug homolog 1

2

0

High-throughput

0.316

High

1121884

CB083
Folate transporter-like protein C2orf83

1

0

High-throughput

0.251

Low

1134046

AT7L2
Ataxin-7-like protein 2

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024