Protein: HOMEZ
Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper-containing factor)

Gene: HOMEZ
Organism: Homo sapiens
Interactions: 141
UniProt ID: Q8IX15

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1220210

DEFI6
Differentially expressed in FDCP 6 homolog

5

3

High-throughput

0.723

High

1220177

SMYD1
Histone-lysine N-methyltransferase SMYD1

4

1

High-throughput

0.700

High

906011

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

3

1

High-throughput

0.667

High

1220199

MED18
Mediator of RNA polymerase II transcription subunit 18

3

0

High-throughput

0.639

High

209107

NCK2
Cytoplasmic protein NCK2

2

10

High-throughput

0.633

High

282693

RNF8
E3 ubiquitin-protein ligase RNF8

2

7

High-throughput

0.633

High

441331

RU2B
U2 small nuclear ribonucleoprotein B''

2

7

High-throughput

0.633

High

702093

RL9
Large ribosomal subunit protein uL6

2

1

High-throughput

0.633

High

871432

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

2

3

High-throughput

0.633

High

902659

SUMO2
Small ubiquitin-related modifier 2

2

8

High-throughput

0.633

High

993495

TLE5
TLE family member 5

2

20

High-throughput

0.633

High

1037985

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

2

1

High-throughput

0.633

High

1051975

ELOA1
Elongin-A

2

2

High-throughput

0.633

High

1220185

AEN
Apoptosis-enhancing nuclease

2

2

High-throughput

0.633

High

1220201

TRAF4
TNF receptor-associated factor 4

2

6

High-throughput

0.633

High

1220209

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

2

3

High-throughput

0.633

High

1075206

TEAD4
Transcriptional enhancer factor TEF-3

2

4

High-throughput

0.613

High

1220181

LNX1
E3 ubiquitin-protein ligase LNX

3

1

High-throughput

0.609

High

132933

SDCB1
Syntenin-1

2

0

High-throughput

0.606

High

1062963

MD2BP
MAD2L1-binding protein

2

0

High-throughput

0.606

High

1220174

CENPS
Centromere protein S

2

0

High-throughput

0.606

High

1220220

COE1
Transcription factor COE1

2

0

High-throughput

0.606

High

647093

1433T
14-3-3 protein theta

2

8

High-throughput

0.601

High

683528

1433B
14-3-3 protein beta/alpha

2

8

High-throughput

0.601

High

904831

1433G
14-3-3 protein gamma

2

8

High-throughput

0.601

High

927278

1433Z
14-3-3 protein zeta/delta

2

8

High-throughput

0.601

High

982250

1433F
14-3-3 protein eta

2

8

High-throughput

0.601

High

1220184

SH3R2
E3 ubiquitin-protein ligase SH3RF2

2

2

High-throughput

0.584

High

1220195

LRRC7
Leucine-rich repeat-containing protein 7

2

1

High-throughput

0.584

High

1220226

RM11
Large ribosomal subunit protein uL11m

2

1

High-throughput

0.578

High

312076

ZBT7A
Zinc finger and BTB domain-containing protein 7A

1

3

High-throughput

0.573

High

853360

IMA1
Importin subunit alpha-1

1

2

High-throughput

0.573

High

924687

GRB2
Growth factor receptor-bound protein 2

1

10

High-throughput

0.573

High

1025165

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

3

High-throughput

0.573

High

1054421

RBM39
RNA-binding protein 39

1

5

High-throughput

0.573

High

237261

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.549

High

1017164

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

High-throughput

0.541

High

1089525

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

5

High-throughput

0.536

High

997489

Q08AM8
SH3 domain containing ring finger 2

1

2

High-throughput

0.515

High

1071477

ZMY11
Zinc finger MYND domain-containing protein 11

1

15

High-throughput

0.501

High

63533

ZSA5B
Zinc finger and SCAN domain-containing protein 5B

1

9

High-throughput

0.481

High

125901

CDC7
Cell division cycle 7-related protein kinase

1

2

High-throughput

0.481

High

170685

AXIN1
Axin-1

1

2

High-throughput

0.481

High

181934

MAFG
Transcription factor MafG

1

5

High-throughput

0.481

High

198016

PHF1
PHD finger protein 1

1

4

High-throughput

0.481

High

277521

CCNK
Cyclin-K

1

1

High-throughput

0.481

High

473684

ZN688
Zinc finger protein 688

1

8

High-throughput

0.481

High

532315

ZNF35
Zinc finger protein 35

1

3

High-throughput

0.481

High

535461

GFAP
Glial fibrillary acidic protein

1

9

High-throughput

0.481

High

557733

NCK1
SH2/SH3 adapter protein NCK1

1

10

High-throughput

0.481

High

607829

USF1
Upstream stimulatory factor 1

1

7

High-throughput

0.481

High

622116

ZBT25
Zinc finger and BTB domain-containing protein 25

1

10

High-throughput

0.481

High

637477

PSA1
Proteasome subunit alpha type-1

1

4

High-throughput

0.481

High

638534

RBTN1
Rhombotin-1

1

19

High-throughput

0.481

High

658990

MK01
Mitogen-activated protein kinase 1

1

1

High-throughput

0.481

High

735074

ZNF76
Zinc finger protein 76

1

4

High-throughput

0.481

High

789029

TXK
Tyrosine-protein kinase TXK

1

7

High-throughput

0.481

High

836597

ZN165
Zinc finger protein 165

1

8

High-throughput

0.481

High

879133

SUMO3
Small ubiquitin-related modifier 3

1

8

High-throughput

0.481

High

880588

LEG4
Galectin-4

1

1

High-throughput

0.481

High

920498

RS25
Small ribosomal subunit protein eS25

1

1

High-throughput

0.481

High

1047679

IL16
Pro-interleukin-16 [Cleaved into: Interleukin-16

1

2

High-throughput

0.481

High

1048548

VEZF1
Vascular endothelial zinc finger 1

1

4

High-throughput

0.481

High

1063011

MO4L2
Mortality factor 4-like protein 2

1

1

High-throughput

0.481

High

1075123

TCEA2
Transcription elongation factor A protein 2

1

2

High-throughput

0.481

High

1134170

PHF19
PHD finger protein 19

1

4

High-throughput

0.481

High

1153283

PKHA7
Pleckstrin homology domain-containing family A member 7

1

6

High-throughput

0.481

High

1164755

ANR11
Ankyrin repeat domain-containing protein 11

1

9

High-throughput

0.481

High

1220172

CCD13
Coiled-coil domain-containing protein 13

1

4

High-throughput

0.481

High

1220176

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

1

3

High-throughput

0.481

High

1220178

Z280C
Zinc finger protein 280C

1

4

High-throughput

0.481

High

1220179

LMO3
LIM domain only protein 3

1

18

High-throughput

0.481

High

1220182

CCHCR
Coiled-coil alpha-helical rod protein 1

1

4

High-throughput

0.481

High

1220186

PIBF1
Progesterone-induced-blocking factor 1

1

2

High-throughput

0.481

High

1220187

RSLAA
Ras-like protein family member 10A

1

3

High-throughput

0.481

High

1220194

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

9

High-throughput

0.481

High

1220198

RHG09
Rho GTPase-activating protein 9

1

2

High-throughput

0.481

High

1220206

IN80B
INO80 complex subunit B

1

1

High-throughput

0.481

High

1220207

ANKR2
Ankyrin repeat domain-containing protein 2

1

6

High-throughput

0.481

High

1220212

CBX8
Chromobox protein homolog 8

1

5

High-throughput

0.481

High

1220213

NEK6
Serine/threonine-protein kinase Nek6

1

3

High-throughput

0.481

High

1220215

ASB6
Ankyrin repeat and SOCS box protein 6

1

3

High-throughput

0.481

High

1220216

ARP10
Actin-related protein 10

1

3

High-throughput

0.481

High

1220219

ZN629
Zinc finger protein 629

1

1

High-throughput

0.481

High

1220223

ZN580
Zinc finger protein 580

1

8

High-throughput

0.481

High

1220225

TBC30
TBC1 domain family member 30

1

1

High-throughput

0.481

High

171049

TBXT
T-box transcription factor T

1

16

High-throughput

0.479

High

197758

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.479

High

211913

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.479

High

443213

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

505255

EGR2
E3 SUMO-protein ligase EGR2

1

8

High-throughput

0.479

High

641474

PAX6
Paired box protein Pax-6

1

20

High-throughput

0.479

High

679136

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.479

High

818228

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.479

High

831479

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.479

High

839778

LHX2
LIM/homeobox protein Lhx2

1

19

High-throughput

0.479

High

878435

PAX9
Paired box protein Pax-9

1

19

High-throughput

0.479

High

917559

H4
Histone H4

1

3

High-throughput

0.479

High

952457

H33
Histone H3.3

1

6

High-throughput

0.479

High

1220175

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

5

High-throughput

0.479

High

1220183

SP7
Transcription factor Sp7

1

15

High-throughput

0.479

High

1220189

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

4

Small-scale

0.479

High

1220196

FEV
Protein FEV

1

18

High-throughput

0.479

High

1220218

ZMYM2
Zinc finger MYM-type protein 2

1

6

High-throughput

0.479

High

50475

A1L1C6
LRRC7 protein

1

3

High-throughput

0.470

High

224810

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

0

High-throughput

0.460

High

253084

HSF2B
Heat shock factor 2-binding protein

1

0

High-throughput

0.460

High

330099

DRC4
Dynein regulatory complex subunit 4

1

0

High-throughput

0.460

High

339265

MOS
Proto-oncogene serine/threonine-protein kinase mos

1

0

High-throughput

0.460

High

549195

ZN250
Zinc finger protein 250

1

0

High-throughput

0.460

High

1046880

BYST
Bystin

1

0

High-throughput

0.460

High

1048705

DGCR6
Protein DGCR6

1

0

High-throughput

0.460

High

1073975

SC23A
Protein transport protein Sec23A

1

0

High-throughput

0.460

High

1199259

BIVM
Basic immunoglobulin-like variable motif-containing protein

1

0

High-throughput

0.460

High

1220180

ZN417
Zinc finger protein 417

1

0

High-throughput

0.460

High

1220190

NEIL2
Endonuclease 8-like 2

1

0

High-throughput

0.460

High

1220192

LENG1
Leukocyte receptor cluster member 1

1

0

High-throughput

0.460

High

1220197

PRP18
Pre-mRNA-splicing factor 18

1

0

High-throughput

0.460

High

1220200

RPP25
Ribonuclease P protein subunit p25

1

0

High-throughput

0.460

High

1220204

SCNM1
Sodium channel modifier 1

1

0

High-throughput

0.460

High

1220205

PDIP3
Polymerase delta-interacting protein 3

1

0

High-throughput

0.460

High

1220214

CB042
Uncharacterized protein C2orf42

1

0

High-throughput

0.460

High

1220217

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.460

High

1220224

VP9D1
VPS9 domain-containing protein 1

1

0

High-throughput

0.460

High

1220227

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

0

High-throughput

0.460

High

327090

GPAN1
G patch domain and ankyrin repeat-containing protein 1

1

2

High-throughput

0.439

High

1205577

F90A1
Protein FAM90A1

1

1

High-throughput

0.439

High

1220191

JKIP2
Janus kinase and microtubule-interacting protein 2

1

3

High-throughput

0.439

High

1220202

KIFC3
Kinesin-like protein KIFC3

1

1

High-throughput

0.439

High

1220203

SYTM
Threonine--tRNA ligase, mitochondrial

1

1

High-throughput

0.439

High

1220211

PARVG
Gamma-parvin

1

8

High-throughput

0.439

High

1220221

CTNA3
Catenin alpha-3

1

2

High-throughput

0.439

High

1220188

RPGR
X-linked retinitis pigmentosa GTPase regulator

1

0

High-throughput

0.282

High

850265

KCNQ1
Potassium voltage-gated channel subfamily KQT member 1

1

0

High-throughput

0.279

Low

311948

SYFM
Phenylalanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.251

Low

1110175

T10IP
Testis-specific protein 10-interacting protein

1

0

High-throughput

0.251

Low

1217929

Q8IVT4
Hypothetical MGC50722

1

0

High-throughput

0.251

Low

1220173

CF206
Cilia- and flagella-associated protein 206

1

0

High-throughput

0.251

Low

1220193

ZMY19
Zinc finger MYND domain-containing protein 19

1

0

High-throughput

0.251

Low

1220208

ENKD1
Enkurin domain-containing protein 1

1

0

High-throughput

0.251

Low

1220222

OSGI1
Oxidative stress-induced growth inhibitor 1

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024