Protein: A2ML1
Alpha-2-macroglobulin-like protein 1 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9)

Gene: A2ML1
Organism: Homo sapiens
Interactions: 107
UniProt ID: A8K2U0

Gene Ontology (top 5):
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005615 - extracellular space
GO:0030414 - peptidase inhibitor activity
GO:0052548 - regulation of endopeptidase activity
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

66368

ANF
Natriuretic peptides A

2

1

High-throughput

0.552

High

66369

FRIH
Ferritin heavy chain

2

1

High-throughput

0.552

High

66451

SCN3B
Sodium channel regulatory subunit beta-3

1

3

High-throughput

0.514

High

66407

ZFAN4
AN1-type zinc finger protein 4

2

1

High-throughput

0.504

High

66415

FRMD1
FERM domain-containing protein 1

2

1

High-throughput

0.504

High

66424

GMCL1
Germ cell-less protein-like 1

2

1

High-throughput

0.504

High

66426

CDK15
Cyclin-dependent kinase 15

2

2

High-throughput

0.504

High

66443

L2HDH
L-2-hydroxyglutarate dehydrogenase, mitochondrial

2

1

High-throughput

0.504

High

66444

UD110
UDP-glucuronosyltransferase 1A10

2

1

High-throughput

0.504

High

66448

TB22B
TBC1 domain family member 22B

2

1

High-throughput

0.504

High

66450

GPT2L
G patch domain-containing protein 2-like

2

1

High-throughput

0.504

High

66355

UPK1A
Uroplakin-1a

1

1

High-throughput

0.445

High

66362

RASF9
Ras association domain-containing protein 9

1

1

High-throughput

0.445

High

66374

AATC
Aspartate aminotransferase, cytoplasmic

1

3

High-throughput

0.445

High

66377

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

5

High-throughput

0.445

High

66380

PI4KA
Phosphatidylinositol 4-kinase alpha

1

3

High-throughput

0.445

High

66389

FSTL1
Follistatin-related protein 1

1

2

High-throughput

0.445

High

66393

STK11
Serine/threonine-protein kinase STK11

1

1

High-throughput

0.445

High

66438

SPTN4
Spectrin beta chain, non-erythrocytic 4

1

2

High-throughput

0.445

High

66458

GSTK1
Glutathione S-transferase kappa 1

1

1

High-throughput

0.445

High

66419

GP148
Probable G-protein coupled receptor 148

1

7

High-throughput

0.437

High

66391

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.426

High

50994

PL8L1
PLAC8-like protein 1

1

1

High-throughput

0.407

High

62070

EPAB2
Embryonic polyadenylate-binding protein 2

1

1

High-throughput

0.407

High

66356

RTCA
RNA 3'-terminal phosphate cyclase

1

1

High-throughput

0.407

High

66357

P2RX6
P2X purinoceptor 6

1

4

High-throughput

0.407

High

66358

CP110
Centriolar coiled-coil protein of 110 kDa

1

1

High-throughput

0.407

High

66360

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.407

High

66361

FOXH1
Forkhead box protein H1

1

9

High-throughput

0.407

High

66363

TOX4
TOX high mobility group box family member 4

1

7

High-throughput

0.407

High

66364

OR2A4
Olfactory receptor 2A4

1

3

High-throughput

0.407

High

66365

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.407

High

66366

MBD4
Methyl-CpG-binding domain protein 4

1

2

High-throughput

0.407

High

66367

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

1

High-throughput

0.407

High

66371

THA
Thyroid hormone receptor alpha

1

1

High-throughput

0.407

High

66372

PIM1
Serine/threonine-protein kinase pim-1

1

1

High-throughput

0.407

High

66373

ADT3
ADP/ATP translocase 3

1

3

High-throughput

0.407

High

66375

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

2

High-throughput

0.407

High

66376

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

1

High-throughput

0.407

High

66378

CCR1
C-C chemokine receptor type 1

1

5

High-throughput

0.407

High

66379

GRK4
G protein-coupled receptor kinase 4

1

1

High-throughput

0.407

High

66381

PCP4
Calmodulin regulator protein PCP4

1

1

High-throughput

0.407

High

66382

ASCL1
Achaete-scute homolog 1

1

2

High-throughput

0.407

High

66383

NDST2
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

1

1

High-throughput

0.407

High

66384

STX17
Syntaxin-17

1

4

High-throughput

0.407

High

66385

DSCR6
Protein ripply3

1

2

High-throughput

0.407

High

66386

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

4

High-throughput

0.407

High

66387

HSF2
Heat shock factor protein 2

1

1

High-throughput

0.407

High

66388

GABPA
GA-binding protein alpha chain

1

1

High-throughput

0.407

High

66390

FOXD4
Forkhead box protein D4

1

4

High-throughput

0.407

High

66392

ZN154
Zinc finger protein 154

1

1

High-throughput

0.407

High

66394

BAK
Bcl-2 homologous antagonist/killer

1

1

High-throughput

0.407

High

66395

UPP1
Uridine phosphorylase 1

1

1

High-throughput

0.407

High

66396

INSC
Protein inscuteable homolog

1

1

High-throughput

0.407

High

66397

CR021
UPF0711 protein C18orf21

1

3

High-throughput

0.407

High

66398

LRC10
Leucine-rich repeat-containing protein 10

1

1

High-throughput

0.407

High

66399

BEX5
Protein BEX5

1

1

High-throughput

0.407

High

66400

MYOME
Myomegalin

1

3

High-throughput

0.407

High

66401

MRM1
rRNA methyltransferase 1, mitochondrial

1

2

High-throughput

0.407

High

66402

APTX
Aprataxin

1

1

High-throughput

0.407

High

66403

ZN550
Zinc finger protein 550

1

1

High-throughput

0.407

High

66404

MOGT3
2-acylglycerol O-acyltransferase 3

1

1

High-throughput

0.407

High

66405

COA5
Cytochrome c oxidase assembly factor 5

1

1

High-throughput

0.407

High

66406

AROS
Active regulator of SIRT1

1

1

High-throughput

0.407

High

66408

CERS3
Ceramide synthase 3

1

2

High-throughput

0.407

High

66409

YAF2
YY1-associated factor 2

1

5

High-throughput

0.407

High

66410

UBAD2
UBA-like domain-containing protein 2

1

1

High-throughput

0.407

High

66411

NRSN1
Neurensin-1

1

3

High-throughput

0.407

High

66412

S39AB
Zinc transporter ZIP11

1

1

High-throughput

0.407

High

66413

FGRL1
Fibroblast growth factor receptor-like 1

1

1

High-throughput

0.407

High

66414

CCYL1
Cyclin-Y-like protein 1

1

1

High-throughput

0.407

High

66416

PI4P1
Putative inactive phosphatidylinositol 4-kinase alpha-like protein P1

1

2

High-throughput

0.407

High

66417

FNDC5
Fibronectin type III domain-containing protein 5

1

3

High-throughput

0.407

High

66418

NFAM1
NFAT activation molecule 1

1

1

High-throughput

0.407

High

66420

RHBL4
Rhomboid-related protein 4

1

4

High-throughput

0.407

High

66421

PIGT
GPI transamidase component PIG-T

1

3

High-throughput

0.407

High

66422

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

4

High-throughput

0.407

High

66423

SARAF
Store-operated calcium entry-associated regulatory factor

1

3

High-throughput

0.407

High

66425

FMNL2
Formin-like protein 2

1

1

High-throughput

0.407

High

66427

TEFM
Transcription elongation factor, mitochondrial

1

1

High-throughput

0.407

High

66428

FCRL5
Fc receptor-like protein 5

1

3

High-throughput

0.407

High

66429

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

5

High-throughput

0.407

High

66430

TREX2
Three prime repair exonuclease 2

1

1

High-throughput

0.407

High

66431

SH23A
SH2 domain-containing protein 3A

1

3

High-throughput

0.407

High

66432

PXL2A
Peroxiredoxin-like 2A

1

1

High-throughput

0.407

High

66433

MMTA2
Multiple myeloma tumor-associated protein 2

1

1

High-throughput

0.407

High

66434

5NT1A
Cytosolic 5'-nucleotidase 1A

1

1

High-throughput

0.407

High

66435

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

4

High-throughput

0.407

High

66436

SRRT
Serrate RNA effector molecule homolog

1

2

High-throughput

0.407

High

66437

PDIP3
Polymerase delta-interacting protein 3

1

1

High-throughput

0.407

High

66439

FBX44
F-box only protein 44

1

4

High-throughput

0.407

High

66440

DUS21
Dual specificity protein phosphatase 21

1

2

High-throughput

0.407

High

66441

ZDHC6
Palmitoyltransferase ZDHHC6

1

2

High-throughput

0.407

High

66442

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

2

High-throughput

0.407

High

66445

GPN1
GPN-loop GTPase 1

1

1

High-throughput

0.407

High

66446

MBNL1
Muscleblind-like protein 1

1

3

High-throughput

0.407

High

66447

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.407

High

66449

KLH11
Kelch-like protein 11

1

1

High-throughput

0.407

High

66452

TLR7
Toll-like receptor 7

1

1

High-throughput

0.407

High

66453

GSKIP
GSK3B-interacting protein

1

1

High-throughput

0.407

High

66454

THA10
THAP domain-containing protein 10

1

1

High-throughput

0.407

High

66455

PHF11
PHD finger protein 11

1

5

High-throughput

0.407

High

66456

COR1C
Coronin-1C

1

2

High-throughput

0.407

High

66457

SSUH2
Protein SSUH2 homolog

1

4

High-throughput

0.407

High

66459

RN115
E3 ubiquitin-protein ligase RNF115

1

2

High-throughput

0.407

High

66359

ZSC12
Zinc finger and SCAN domain-containing protein 12

2

0

High-throughput

0.288

High

66370

F153B
Protein FAM153B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024