Protein: PPAP
Prostatic acid phosphatase (PAP) (EC 3.1.3.2) (5'-nucleotidase) (5'-NT) (EC 3.1.3.5) (Acid phosphatase 3) (Ecto-5'-nucleotidase) (Protein tyrosine phosphatase ACP3) (EC 3.1.3.48) (Thiamine monophosphatase) (TMPase) [Cleaved into: PAPf39]

Gene: PPAP, ACP3
Organism: Homo sapiens
Interactions: 142
UniProt ID: P15309

Gene Ontology (top 5):
GO:0003993 - acid phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005764 - lysosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

546811

PPAP
Prostatic acid phosphatase

3

5

Small-scale

0.843

High

546861

IL31R
Interleukin-31 receptor subunit alpha

2

1

High-throughput

0.628

High

546906

FBXL4
F-box/LRR-repeat protein 4

2

1

High-throughput

0.628

High

217434

AIRE
Autoimmune regulator

2

0

High-throughput

0.602

High

351515

ANF
Natriuretic peptides A

2

0

High-throughput

0.602

High

365142

FRIH
Ferritin heavy chain

2

0

High-throughput

0.602

High

546843

ZIC1
Zinc finger protein ZIC 1

2

0

High-throughput

0.602

High

546856

CC103
Coiled-coil domain-containing protein 103

2

0

High-throughput

0.602

High

546867

CPLX3
Complexin-3

2

0

High-throughput

0.602

High

546877

CDK15
Cyclin-dependent kinase 15

2

0

High-throughput

0.602

High

546911

KIF3A
Kinesin-like protein KIF3A

2

0

High-throughput

0.602

High

546888

DUS21
Dual specificity protein phosphatase 21

2

0

High-throughput

0.595

High

274918

RENR
Renin receptor

2

0

High-throughput

0.585

High

546872

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

1

High-throughput

0.536

High

546912

RN115
E3 ubiquitin-protein ligase RNF115

1

1

High-throughput

0.536

High

127095

FOXN3
Forkhead box protein N3

1

0

High-throughput

0.513

High

158735

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.513

High

201514

DHH
Desert hedgehog protein

1

0

High-throughput

0.513

High

209310

TSN6
Tetraspanin-6

1

0

High-throughput

0.513

High

215799

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

0

High-throughput

0.513

High

265595

E2F6
Transcription factor E2F6

1

0

High-throughput

0.513

High

281977

ANXA9
Annexin A9

1

0

High-throughput

0.513

High

296602

TPPP
Tubulin polymerization-promoting protein

1

0

High-throughput

0.513

High

309359

MBD4
Methyl-CpG-binding domain protein 4

1

0

High-throughput

0.513

High

329079

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.513

High

345304

FOS
Protein c-Fos

1

0

High-throughput

0.513

High

392907

IFNW1
Interferon omega-1

1

0

High-throughput

0.513

High

445936

NMB
Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]

1

0

High-throughput

0.513

High

518233

ADT3
ADP/ATP translocase 3

1

0

High-throughput

0.513

High

546812

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

546813

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

0

High-throughput

0.513

High

546814

CCNC
Cyclin-C

1

0

High-throughput

0.513

High

546819

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

546825

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.513

High

546826

PCP4
Calmodulin regulator protein PCP4

1

0

High-throughput

0.513

High

546833

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

546834

DSCR6
Protein ripply3

1

0

High-throughput

0.513

High

546836

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.513

High

546838

HSF2
Heat shock factor protein 2

1

0

High-throughput

0.513

High

546839

GABPA
GA-binding protein alpha chain

1

0

High-throughput

0.513

High

546845

LRC10
Leucine-rich repeat-containing protein 10

1

0

High-throughput

0.513

High

546853

ZN550
Zinc finger protein 550

1

0

High-throughput

0.513

High

546855

LACC1
Purine nucleoside phosphorylase LACC1

1

0

High-throughput

0.513

High

546880

TREX2
Three prime repair exonuclease 2

1

0

High-throughput

0.513

High

546884

5NT1A
Cytosolic 5'-nucleotidase 1A

1

0

High-throughput

0.513

High

546885

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.513

High

546887

TX101
Testis-expressed protein 101

1

0

High-throughput

0.513

High

546891

TSSP
Thymus-specific serine protease

1

0

High-throughput

0.513

High

546892

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

546896

KLH11
Kelch-like protein 11

1

0

High-throughput

0.513

High

546897

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

0

High-throughput

0.513

High

546901

PEMT
Phosphatidylethanolamine N-methyltransferase

1

0

High-throughput

0.513

High

546905

PHF11
PHD finger protein 11

1

0

High-throughput

0.513

High

546909

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

383578

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

0

Small-scale

0.499

High

546889

L2HDH
L-2-hydroxyglutarate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

162383

XPO1
Exportin-1

1

4

High-throughput

0.479

High

207882

XPOT
Exportin-T

1

4

High-throughput

0.479

High

299836

ERLN2
Erlin-2

1

1

High-throughput

0.479

High

380980

SEMG1
Semenogelin-1

1

1

High-throughput

0.479

High

423130

PDIA1
Protein disulfide-isomerase

1

6

High-throughput

0.479

High

426507

KLK3
Prostate-specific antigen

1

3

High-throughput

0.479

High

428661

TRY1
Serine protease 1

1

2

High-throughput

0.479

High

475306

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.479

High

546815

ZA2G
Zinc-alpha-2-glycoprotein

1

1

High-throughput

0.479

High

546816

CALR
Calreticulin

1

5

High-throughput

0.479

High

546817

CALX
Calnexin

1

5

High-throughput

0.479

High

546818

PDIA3
Protein disulfide-isomerase A3

1

6

High-throughput

0.479

High

546822

MTOR
Serine/threonine-protein kinase mTOR

1

1

High-throughput

0.479

High

546828

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.479

High

546829

EFNA3
Ephrin-A3

1

3

High-throughput

0.479

High

546830

EFNA4
Ephrin-A4

1

3

High-throughput

0.479

High

546831

XPO2
Exportin-2

1

1

High-throughput

0.479

High

546837

SEMG2
Semenogelin-2

1

1

High-throughput

0.479

High

546848

ECM29
Proteasome adapter and scaffold protein ECM29

1

2

High-throughput

0.479

High

546868

GCN1
Stalled ribosome sensor GCN1

1

3

High-throughput

0.479

High

546871

TNPO1
Transportin-1

1

1

High-throughput

0.479

High

546890

XPO5
Exportin-5

1

4

High-throughput

0.479

High

380935

SHBG
Sex hormone-binding globulin

1

0

Small-scale

0.460

High

435940

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.458

High

437252

4F2
Amino acid transporter heavy chain SLC3A2

1

0

High-throughput

0.458

High

438680

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.458

High

546821

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.458

High

546823

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

546832

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

546841

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.458

High

546846

S27A3
Long-chain fatty acid transport protein 3

1

0

High-throughput

0.458

High

546854

MON2
Protein MON2 homolog

1

0

High-throughput

0.458

High

546857

ABD12
Lysophosphatidylserine lipase ABHD12

1

0

High-throughput

0.458

High

546862

CIP2A
Protein CIP2A

1

0

High-throughput

0.458

High

546869

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

546870

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

High-throughput

0.458

High

546874

ASTRA
Protein Aster-A

1

0

High-throughput

0.458

High

546876

SEH1
Nucleoporin SEH1

1

0

High-throughput

0.458

High

546882

TMM43
Transmembrane protein 43

1

0

High-throughput

0.458

High

546886

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

546895

FANCI
Fanconi anemia group I protein

1

0

High-throughput

0.458

High

546900

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

0

High-throughput

0.458

High

546903

DJB11
DnaJ homolog subfamily B member 11

1

0

High-throughput

0.458

High

546907

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.458

High

161013

CLGN
Calmegin

1

5

High-throughput

0.437

High

546824

STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

1

1

High-throughput

0.437

High

546835

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

1

High-throughput

0.437

High

546863

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

1

High-throughput

0.437

High

546904

SEC63
Translocation protein SEC63 homolog

1

1

High-throughput

0.437

High

546908

DJC16
DnaJ homolog subfamily C member 16

1

4

High-throughput

0.437

High

546913

TNPO3
Transportin-3

1

4

High-throughput

0.437

High

353907

IGHM
Immunoglobulin heavy constant mu

1

0

High-throughput

0.426

High

546840

MMRN1
Multimerin-1

3

0

High-throughput

0.347

High

546894

TB22B
TBC1 domain family member 22B

2

0

High-throughput

0.328

High

546910

FCF1
rRNA-processing protein FCF1 homolog

2

0

High-throughput

0.328

High

50996

PL8L1
PLAC8-like protein 1

1

0

High-throughput

0.279

Low

303641

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

546820

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.279

Low

546827

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.279

Low

546844

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.279

Low

546851

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.279

Low

546859

PLD5
Inactive phospholipase D5

1

0

High-throughput

0.279

Low

546864

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.279

Low

546873

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

546878

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.279

Low

546879

FCRL5
Fc receptor-like protein 5

1

0

High-throughput

0.279

Low

546881

SH23A
SH2 domain-containing protein 3A

1

0

High-throughput

0.279

Low

546883

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

546893

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.279

Low

546899

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.279

Low

100447

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

390698

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

546842

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.249

Low

546847

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

0

High-throughput

0.249

Low

546849

BSPRY
B box and SPRY domain-containing protein

1

0

High-throughput

0.249

Low

546850

ATLA3
Atlastin-3

1

0

High-throughput

0.249

Low

546852

5MP2
eIF5-mimic protein 2

1

0

High-throughput

0.249

Low

546858

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

546860

UBAC2
Ubiquitin-associated domain-containing protein 2

1

0

High-throughput

0.249

Low

546865

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.249

Low

546866

THEM6
Protein THEM6

1

0

High-throughput

0.249

Low

546875

FAF2
FAS-associated factor 2

1

0

High-throughput

0.249

Low

546898

QPCTL
Glutaminyl-peptide cyclotransferase-like protein

1

0

High-throughput

0.249

Low

546902

KS6B2
Ribosomal protein S6 kinase beta-2

1

0

High-throughput

0.249

Low

473242

F153B
Protein FAM153B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024