Protein: INSR
Insulin-like receptor (dIR) (dInr) (EC 2.7.10.1) (Insulin receptor homolog) (dIRH) (Receptor protein-tyrosine kinase InR) [Cleaved into: Insulin-like receptor subunit alpha; Insulin-like receptor subunit beta 1 (Insulin-like receptor subunit beta 170 kDa form) (beta170); Insulin-like receptor subunit beta 2 (Insulin-like receptor subunit beta 90 kDa form) (beta90); 60 kDa C-terminal fragment (Insulin-like receptor free C-terminus)]

Gene: INSR, InR
Organism: Drosophila melanogaster
Interactions: 47
UniProt ID: P09208

Gene Ontology (top 5):
GO:0001700 - embryonic development via the syncytial blastoderm
GO:0002052 - positive regulation of neuroblast proliferation
GO:0004713 - protein tyrosine kinase activity
GO:0005009 - insulin receptor activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

113872

M9PAY7
Pi3K21B, isoform C

3

20

High-throughput

0.827

High

448231

LAR
Tyrosine-protein phosphatase Lar

2

20

Small-scale

0.789

High

448230

INSR
Insulin-like receptor

2

17

Small-scale

0.778

High

448264

IRS1
Insulin receptor substrate 1

8

14

Small-scale

0.746

High

448235

MOEH
Moesin/ezrin/radixin homolog 1

1

20

High-throughput

0.698

High

448233

PTP99
Tyrosine-protein phosphatase 99A

1

20

Small-scale

0.692

High

448244

Q7K137
LD10453p

1

20

Small-scale

0.647

High

448246

INSL5
Probable insulin-like peptide 5

1

1

Small-scale

0.647

High

448232

1433Z
14-3-3 protein zeta

1

20

High-throughput

0.618

High

448255

FLNA
Filamin-A

1

10

High-throughput

0.618

High

448262

PTP61
Tyrosine-protein phosphatase non-receptor type 61F

1

20

Small-scale

0.618

High

365430

HSP83
Heat shock protein 83

2

20

Small-scale

0.586

High

448237

P91634
PI-3 kinase

2

20

High-throughput

0.584

High

186277

O18683
LD42724p

1

20

High-throughput

0.575

High

448240

DYL1
Dynein light chain 1, cytoplasmic

2

0

High-throughput

0.559

High

448242

SEM1A
Semaphorin-1A

1

6

High-throughput

0.536

High

184491

RL15
Large ribosomal subunit protein eL15

2

1

High-throughput

0.533

High

113077

M9NFI9
Spinophilin, isoform J

1

20

High-throughput

0.514

High

448265

Q9XYW6
E3 ubiquitin-protein ligase CHIP

1

17

Small-scale

0.512

High

448247

NCK
SH2/SH3 adapter protein dreadlocks

1

20

High-throughput

0.492

High

448241

CDC37
Hsp90 co-chaperone Cdc37

1

20

Small-scale

0.481

High

432483

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

14

High-throughput

0.479

High

448245

Q7K1R6
LD46221p

1

7

High-throughput

0.479

High

448254

Q9VAY2
Heat shock protein 83

1

20

High-throughput

0.479

High

448256

Q9VFV9
DnaJ-like-2, isoform A

1

20

High-throughput

0.479

High

448261

Q9VV75
AT02348p

1

3

High-throughput

0.479

High

448243

Q4V5V6
GEO10744p1

1

0

Small-scale

0.458

High

448239

Q0E8S4
Semaphorin 1a, isoform D

1

6

High-throughput

0.445

High

90492

E1JGL8
Uncharacterized protein, isoform C

1

7

High-throughput

0.437

High

246659

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.437

High

448234

RSSA
Small ribosomal subunit protein uS2

1

3

High-throughput

0.437

High

448238

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.437

High

448248

RS23
Small ribosomal subunit protein uS12

1

1

High-throughput

0.437

High

448249

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

4

High-throughput

0.437

High

448251

Q9V3W7
LD40489p

1

12

High-throughput

0.437

High

448252

Q9V9W2
Large ribosomal subunit protein eL6

1

2

High-throughput

0.437

High

448253

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.437

High

448258

Q9VGH5
AT27789p

1

20

High-throughput

0.437

High

448263

RS28
Small ribosomal subunit protein eS28

1

1

High-throughput

0.437

High

51992

A1Z720
Uncharacterized protein, isoform A

1

0

High-throughput

0.249

Low

440947

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.249

Low

448236

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.249

Low

448250

Q95RF6
LD34461p

1

0

High-throughput

0.249

Low

448257

Q9VFW4
Elongator complex protein 6

1

0

Small-scale

0.249

Low

448259

Q9VJ19
Large ribosomal subunit protein eL30

1

0

High-throughput

0.249

Low

448260

ZUC
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024