Protein: CPSF6
Cleavage and polyadenylation specificity factor subunit 6

Gene: CPSF6
Organism: Drosophila melanogaster
Interactions: 62
UniProt ID: Q9VSH4

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex
GO:0110104 - mRNA alternative polyadenylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1373615

CDK8
Cyclin-dependent kinase 8

2

9

Small-scale

0.806

High

1373614

Q9VSY2
Cleavage and polyadenylation specificity factor subunit 5

2

5

High-throughput

0.775

High

834210

DOA
Serine/threonine-protein kinase Doa

1

7

Small-scale

0.724

High

1358889

NCBP2
Nuclear cap-binding protein subunit 2

1

19

High-throughput

0.656

High

1364315

Q9VE52
Cleavage stimulation factor 64 kD subunit

1

18

Small-scale

0.618

High

631329

BRM
ATP-dependent helicase brm

2

19

Small-scale

0.584

High

1095816

Q24090
GH08712p

2

7

Small-scale

0.584

High

1228776

Q8MQJ7
Autophagy-related 1, isoform B

1

2

Small-scale

0.553

High

1337347

LAR4
La-related protein Larp4B

1

16

High-throughput

0.553

High

1372933

Q9VR61
Ribosomal protein S6 kinase II, isoform A

1

9

High-throughput

0.553

High

55292

A1ZAK9
P-element somatic inhibitor, isoform A

1

20

High-throughput

0.479

High

112932

M9NF08
ZAP3, isoform D

1

1

High-throughput

0.479

High

844387

DSH
Segment polarity protein dishevelled

1

4

High-throughput

0.479

High

954646

MED20
Mediator of RNA polymerase II transcription subunit 20

1

1

High-throughput

0.479

High

1103854

Q32KD4
Argonaute-1, isoform A

1

12

High-throughput

0.479

High

1115151

YAP1
Transcriptional coactivator yorkie

1

20

High-throughput

0.479

High

1181094

Q7KMQ6
IP16020p

1

5

High-throughput

0.479

High

1182351

Q7KU78
RNA helicase

1

11

High-throughput

0.479

High

1213333

OSA
Trithorax group protein osa

1

20

High-throughput

0.479

High

1229241

MED6
Mediator of RNA polymerase II transcription subunit 6

1

2

High-throughput

0.479

High

1279327

EBI
F-box-like/WD repeat-containing protein ebi

1

13

High-throughput

0.479

High

1364508

MED17
Mediator of RNA polymerase II transcription subunit 17

1

3

High-throughput

0.479

High

1365123

Q9VF03
Brahma associated protein 155 kDa

1

20

High-throughput

0.479

High

1371509

MED27
Mediator of RNA polymerase II transcription subunit 27

1

1

High-throughput

0.479

High

1372888

Q9VR42
Serine/threonine-protein kinase RIO3

1

5

High-throughput

0.479

High

1373435

MED4
Mediator of RNA polymerase II transcription subunit 4

1

2

High-throughput

0.479

High

1373595

MED24
Mediator of RNA polymerase II transcription subunit 24

1

1

High-throughput

0.479

High

1373617

MED11
Mediator of RNA polymerase II transcription subunit 11

1

1

High-throughput

0.479

High

1373618

BAP60
Brahma-associated protein of 60 kDa

1

15

High-throughput

0.479

High

1373621

MED30
Mediator of RNA polymerase II transcription subunit 30

1

1

High-throughput

0.479

High

1373626

MED18
Mediator of RNA polymerase II transcription subunit 18

1

1

High-throughput

0.479

High

1373627

MED15
Mediator of RNA polymerase II transcription subunit 15

1

19

High-throughput

0.479

High

1370816

Q9VMH8
GEO07746p1

1

1

High-throughput

0.464

High

1372992

PNO1
RNA-binding protein pno1

1

1

High-throughput

0.464

High

1182304

MED13
Mediator of RNA polymerase II transcription subunit 13

1

0

High-throughput

0.458

High

1215420

INDRA
Zinc finger protein indra

1

0

High-throughput

0.458

High

1182702

Q7KVF3
Uncharacterized protein

1

1

High-throughput

0.439

High

52845

A1Z813
Secretory 24AB, isoform A

1

14

High-throughput

0.437

High

56320

MED8
Mediator of RNA polymerase II transcription subunit 8

1

1

High-throughput

0.437

High

817635

GAP1
GTPase-activating protein

1

9

High-throughput

0.437

High

980084

KELC
Ring canal kelch protein [Cleaved into: Kelch short protein]

1

3

Small-scale

0.437

High

1229206

ENC
Protein encore

1

8

High-throughput

0.437

High

1280244

Q960F7
SD03629p

1

8

High-throughput

0.437

High

1363908

MED25
Mediator of RNA polymerase II transcription subunit 25

1

15

High-throughput

0.437

High

1371502

Q9VNF8
Protein transport protein SEC23

1

14

High-throughput

0.437

High

1373616

Q9VUB7
PAX transcription activation domain interacting protein

1

9

High-throughput

0.437

High

1373620

Q9W0L7
ubiquitinyl hydrolase 1

1

11

High-throughput

0.437

High

1373622

MED14
Mediator of RNA polymerase II transcription subunit 14

1

18

High-throughput

0.437

High

1373623

MED23
Mediator of RNA polymerase II transcription subunit 23

1

2

High-throughput

0.437

High

1373625

Q9W2S2
Autophagy-related 8a, isoform A

1

16

Small-scale

0.437

High

1248619

Q8SX59
LD42296p

1

1

High-throughput

0.417

High

55458

PTRO
Patronin

1

0

High-throughput

0.265

Low

1367378

CDPF1
Cysteine-rich DPF motif domain-containing protein 1

1

0

High-throughput

0.265

Low

1176793

Q7JQT8
LD41464p

1

0

High-throughput

0.249

Low

1180515

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.249

Low

1250323

Q8T4A8
AT07769p

1

0

High-throughput

0.249

Low

1250628

MESD
LDLR chaperone boca

1

0

High-throughput

0.249

Low

1325830

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.249

Low

1325927

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.249

Low

1369829

Q9VL29
GEO11246p1

1

0

High-throughput

0.249

Low

1373619

Q9VYZ8
GEO08286p1

1

0

High-throughput

0.249

Low

1373624

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024