Protein: LHX8
LIM/homeobox protein Lhx8 (LIM homeobox protein 8)

Gene: LHX8
Organism: Homo sapiens
Interactions: 68
UniProt ID: Q68G74

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001674 - female germ cell nucleus
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1148473

LDB1
LIM domain-binding protein 1

4

20

High-throughput

0.909

High

1148470

FIGLA
Factor in the germline alpha

3

12

High-throughput

0.858

High

210834

LDB2
LIM domain-binding protein 2

2

20

High-throughput

0.783

High

1148490

SSBP4
Single-stranded DNA-binding protein 4

4

20

High-throughput

0.694

High

884183

KLF3
Krueppel-like factor 3

2

13

High-throughput

0.628

High

903736

LMO4
LIM domain transcription factor LMO4

1

20

High-throughput

0.618

High

1148484

ISL2
Insulin gene enhancer protein ISL-2

1

18

High-throughput

0.618

High

1148497

LHX6
LIM/homeobox protein Lhx6

1

19

High-throughput

0.618

High

175972

FOXN1
Forkhead box protein N1

2

8

High-throughput

0.606

High

196621

ZBT24
Zinc finger and BTB domain-containing protein 24

2

4

High-throughput

0.606

High

547817

ATF2
Cyclic AMP-dependent transcription factor ATF-2

2

2

High-throughput

0.606

High

548309

FOSL2
Fos-related antigen 2

2

4

High-throughput

0.606

High

934239

CSK21
Casein kinase II subunit alpha

2

7

High-throughput

0.606

High

1054775

CASL
Enhancer of filamentation 1

2

14

High-throughput

0.606

High

1148472

TBCD1
TBC1 domain family member 1

2

2

High-throughput

0.606

High

1148479

CCHCR
Coiled-coil alpha-helical rod protein 1

2

2

High-throughput

0.606

High

1148481

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

1

High-throughput

0.606

High

1148495

ABI2
Abl interactor 2

2

20

High-throughput

0.606

High

1148471

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

4

High-throughput

0.594

High

1148488

SLD5
DNA replication complex GINS protein SLD5

2

0

High-throughput

0.580

High

802621

CRK
Adapter molecule crk

2

20

High-throughput

0.576

High

1148476

NUTM1
NUT family member 1

1

1

High-throughput

0.573

High

199513

EFS
Embryonal Fyn-associated substrate

2

12

High-throughput

0.553

High

943677

KRT85
Keratin, type II cuticular Hb5

2

4

High-throughput

0.553

High

1148478

BANP
Protein BANP

2

4

High-throughput

0.553

High

1148494

TB22B
TBC1 domain family member 22B

2

2

High-throughput

0.553

High

562653

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

2

1

High-throughput

0.542

High

1148491

SSBP3
Single-stranded DNA-binding protein 3

1

20

High-throughput

0.536

High

1148499

PYGO1
Pygopus homolog 1

1

20

High-throughput

0.536

High

1148477

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

3

High-throughput

0.523

High

2148

SIK1B
Putative serine/threonine-protein kinase SIK1B

1

1

High-throughput

0.515

High

791656

HD
Huntingtin

1

2

High-throughput

0.515

High

1148485

Q96QL7
ATF6B protein

1

1

High-throughput

0.515

High

1148498

RNF11
RING finger protein 11

1

3

High-throughput

0.515

High

203710

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

9

High-throughput

0.508

High

170669

AXIN1
Axin-1

1

2

High-throughput

0.481

High

883227

SIK1
Serine/threonine-protein kinase SIK1

1

1

High-throughput

0.481

High

1148486

ATF6B
Cyclic AMP-dependent transcription factor ATF-6 beta

1

6

High-throughput

0.481

High

152657

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

164232

ZN609
Zinc finger protein 609

1

9

High-throughput

0.479

High

718930

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

846799

SMCA2
Probable global transcription activator SNF2L2

1

11

High-throughput

0.479

High

946646

SSBP2
Single-stranded DNA-binding protein 2

1

20

High-throughput

0.479

High

958942

TFAM
Transcription factor A, mitochondrial

1

17

High-throughput

0.479

High

980622

TLE1
Transducin-like enhancer protein 1

1

11

High-throughput

0.479

High

1147444

ARID2
AT-rich interactive domain-containing protein 2

1

20

High-throughput

0.479

High

1148474

PB1
Protein polybromo-1

1

15

High-throughput

0.479

High

1148480

PHF10
PHD finger protein 10

1

20

High-throughput

0.479

High

1148482

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

1148483

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

18

High-throughput

0.479

High

1148487

PYGO2
Pygopus homolog 2

1

11

High-throughput

0.479

High

1148489

PCGF1
Polycomb group RING finger protein 1

1

8

High-throughput

0.479

High

1148493

BRD7
Bromodomain-containing protein 7

1

8

High-throughput

0.479

High

103755

G5E9A7
DM1 locus, WD repeat containing

1

3

High-throughput

0.470

High

218020

PEX1
Peroxisomal ATPase PEX1

1

1

High-throughput

0.470

High

231562

KIF1B
Kinesin-like protein KIF1B

1

3

High-throughput

0.470

High

281680

WFS1
Wolframin

1

1

High-throughput

0.470

High

609350

FGFR3
Fibroblast growth factor receptor 3

1

5

High-throughput

0.470

High

660561

GRN
Progranulin

1

1

High-throughput

0.470

High

1060455

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

1

High-throughput

0.470

High

1121053

GLE1
mRNA export factor GLE1

1

1

High-throughput

0.470

High

1148475

Q86WV8
TSC complex subunit 1

1

1

High-throughput

0.470

High

1148496

UBQL1
Ubiquilin-1

1

3

High-throughput

0.470

High

3210

A0A0S2Z4M1
Axin-1

1

2

High-throughput

0.457

High

131726

BCL9
B-cell CLL/lymphoma 9 protein

1

20

High-throughput

0.437

High

1022519

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

1

High-throughput

0.437

High

1148492

GRPE1
GrpE protein homolog 1, mitochondrial

1

1

High-throughput

0.437

High

821261

TCPE
T-complex protein 1 subunit epsilon

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024