Protein: SLD5
DNA replication complex GINS protein SLD5 (GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed]

Gene: SLD5, GINS4
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q9BRT9

Gene Ontology (top 5):
GO:0000727 - double-strand break repair via break-induced replication
GO:0000811 - GINS complex
GO:0001833 - inner cell mass cell proliferation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1310665

PSF2
DNA replication complex GINS protein PSF2

8

6

Small-scale

0.972

High

1310655

PSF3
DNA replication complex GINS protein PSF3

6

4

Small-scale

0.946

High

264230

CDC45
Cell division control protein 45 homolog

5

3

Small-scale

0.918

High

832679

MCM2
DNA replication licensing factor MCM2

5

16

Small-scale

0.918

High

709029

MCM7
DNA replication licensing factor MCM7

4

15

Small-scale

0.895

High

1058090

PSF1
DNA replication complex GINS protein PSF1

4

4

Small-scale

0.893

High

883233

SIK1
Serine/threonine-protein kinase SIK1

5

1

Small-scale

0.725

High

1310657

TIPIN
TIMELESS-interacting protein

3

2

High-throughput

0.667

High

555625

H2AX
Histone H2AX

2

1

High-throughput

0.628

High

1298803

TOX2
TOX high mobility group box family member 2

2

1

High-throughput

0.628

High

627346

MCM3
DNA replication licensing factor MCM3

1

17

Small-scale

0.618

High

708503

MCM4
DNA replication licensing factor MCM4

1

13

Small-scale

0.618

High

708751

MCM5
DNA replication licensing factor MCM5

1

15

Small-scale

0.618

High

1055616

MCM6
DNA replication licensing factor MCM6

1

17

Small-scale

0.618

High

652096

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

1

Small-scale

0.611

High

1310662

CNBP1
Beta-catenin-interacting protein 1

2

1

High-throughput

0.606

High

943157

KC1G2
Casein kinase I isoform gamma-2

2

0

High-throughput

0.602

High

1148488

LHX8
LIM/homeobox protein Lhx8

2

0

High-throughput

0.580

High

1296364

ASPP1
Apoptosis-stimulating of p53 protein 1

2

0

High-throughput

0.580

High

1296990

KI16B
Kinesin-like protein KIF16B

2

0

High-throughput

0.580

High

1310658

PBX4
Pre-B-cell leukemia transcription factor 4

2

0

High-throughput

0.580

High

1310660

DMAP1
DNA methyltransferase 1-associated protein 1

2

0

High-throughput

0.580

High

295194

RECQ4
ATP-dependent DNA helicase Q4

2

0

Small-scale

0.559

High

1310656

MCMBP
Mini-chromosome maintenance complex-binding protein

2

0

Small-scale

0.559

High

239391

CC14B
Dual specificity protein phosphatase CDC14B

1

1

High-throughput

0.536

High

996863

SSRP1
FACT complex subunit SSRP1

1

1

High-throughput

0.536

High

1274598

TP4A1
Protein tyrosine phosphatase type IVA 1

1

1

High-throughput

0.536

High

2149

SIK1B
Putative serine/threonine-protein kinase SIK1B

1

1

High-throughput

0.515

High

553571

RFA2
Replication protein A 32 kDa subunit

1

0

Small-scale

0.513

High

664120

T2EB
Transcription initiation factor IIE subunit beta

1

0

High-throughput

0.513

High

721294

RFA3
Replication protein A 14 kDa subunit

1

0

Small-scale

0.513

High

952590

H33
Histone H3.3

1

0

High-throughput

0.513

High

1310659

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

High-throughput

0.513

High

456134

DPOLA
DNA polymerase alpha catalytic subunit

1

7

Small-scale

0.501

High

658425

DPOD1
DNA polymerase delta catalytic subunit

1

7

Small-scale

0.501

High

992307

DPOE1
DNA polymerase epsilon catalytic subunit A

1

7

Small-scale

0.501

High

1264935

LZIC
Protein LZIC

1

1

High-throughput

0.489

High

391875

H2A1B
Histone H2A type 1-B/E

1

1

High-throughput

0.479

High

244863

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

714576

GRK5
G protein-coupled receptor kinase 5

1

0

High-throughput

0.458

High

777702

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

882531

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

1171458

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1310663

DONS
Protein downstream neighbor of Son

1

0

Small-scale

0.458

High

1310664

DS13B
Dual specificity protein phosphatase 13B

1

0

High-throughput

0.458

High

1310661

BIN3
Bridging integrator 3

2

0

High-throughput

0.316

High

1166258

AMTN
Amelotin

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024