Protein: FLNB
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)

Gene: FLNB
Organism: Homo sapiens
Interactions: 205
UniProt ID: O75369

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0003334 - keratinocyte development
GO:0003382 - epithelial cell morphogenesis
GO:0003723 - RNA binding
GO:0003779 - actin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

261201

FLNA
Filamin-A

4

17

Small-scale

0.905

High

261175

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

2

High-throughput

0.743

High

234453

DSCAM
Cell adhesion molecule DSCAM

1

13

High-throughput

0.698

High

261263

MYPC2
Myosin-binding protein C, fast-type

1

20

High-throughput

0.698

High

261173

FINC
Fibronectin

1

20

High-throughput

0.691

High

261221

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

8

High-throughput

0.691

High

261270

MARE1
Microtubule-associated protein RP/EB family member 1

1

7

High-throughput

0.691

High

261181

ITB1
Integrin beta-1

1

20

Small-scale

0.680

High

261180

ISG15
Ubiquitin-like protein ISG15

3

11

Small-scale

0.657

High

261334

ANLN
Anillin

3

9

High-throughput

0.656

High

261190

CFTR
Cystic fibrosis transmembrane conductance regulator

3

8

High-throughput

0.650

High

261171

MYC
Myc proto-oncogene protein

3

10

High-throughput

0.640

High

261299

FBLI1
Filamin-binding LIM protein 1

2

20

Small-scale

0.636

High

261207

ARRB2
Beta-arrestin-2

2

3

High-throughput

0.628

High

261341

HSPB7
Heat shock protein beta-7

2

14

High-throughput

0.628

High

261179

ITB3
Integrin beta-3

1

20

Small-scale

0.621

High

261196

ITB6
Integrin beta-6

1

20

Small-scale

0.621

High

261239

ACTA
Actin, aortic smooth muscle

1

19

High-throughput

0.618

High

261242

ACTC
Actin, alpha cardiac muscle 1

1

19

High-throughput

0.618

High

261262

FLNC
Filamin-C

1

18

High-throughput

0.618

High

261288

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.618

High

261198

VCAM1
Vascular cell adhesion protein 1

2

19

High-throughput

0.601

High

261251

G3BP1
Ras GTPase-activating protein-binding protein 1

2

2

High-throughput

0.601

High

261232

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

2

4

Small-scale

0.595

High

261277

OTUD1
OTU domain-containing protein 1

3

8

Small-scale

0.593

High

261164

FLNB
Filamin-B

1

16

Small-scale

0.590

High

226046

PRKN
E3 ubiquitin-protein ligase parkin

2

8

High-throughput

0.584

High

261184

CALM3
Calmodulin-3

1

5

High-throughput

0.575

High

261255

TBB3
Tubulin beta-3 chain

1

2

High-throughput

0.575

High

261289

TBA1A
Tubulin alpha-1A chain

1

4

High-throughput

0.575

High

261225

PSN1
Presenilin-1

1

5

Small-scale

0.573

High

261226

PSN2
Presenilin-2

1

5

Small-scale

0.573

High

261240

GRB2
Growth factor receptor-bound protein 2

2

20

High-throughput

0.571

High

261177

HSPB1
Heat shock protein beta-1

1

11

High-throughput

0.541

High

261228

FXR1
RNA-binding protein FXR1

1

9

High-throughput

0.541

High

131756

LAD1
Ladinin-1

1

11

High-throughput

0.536

High

261188

RALA
Ras-related protein Ral-A

1

8

High-throughput

0.536

High

261212

MYH9
Myosin-9

1

9

High-throughput

0.536

High

261222

CAZA2
F-actin-capping protein subunit alpha-2

1

7

High-throughput

0.536

High

261223

CAPZB
F-actin-capping protein subunit beta

1

4

High-throughput

0.536

High

261237

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

8

High-throughput

0.536

High

261241

RAC1
Ras-related C3 botulinum toxin substrate 1

1

11

Small-scale

0.536

High

261246

CALD1
Caldesmon

1

20

High-throughput

0.536

High

261250

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

14

Small-scale

0.536

High

261252

CENPR
Centromere protein R

1

1

High-throughput

0.536

High

261257

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

8

High-throughput

0.536

High

261260

SCRB2
Lysosome membrane protein 2

1

2

High-throughput

0.536

High

261261

SRC8
Src substrate cortactin

1

18

High-throughput

0.536

High

261272

DREB
Drebrin

1

13

High-throughput

0.536

High

261303

MY18A
Unconventional myosin-XVIIIa

1

17

High-throughput

0.536

High

261310

VMP1
Vacuole membrane protein 1

1

2

High-throughput

0.536

High

261311

MYO19
Unconventional myosin-XIX

1

13

High-throughput

0.536

High

261328

PHAX
Phosphorylated adapter RNA export protein

1

1

High-throughput

0.536

High

261344

LIMA1
LIM domain and actin-binding protein 1

1

17

High-throughput

0.536

High

261345

NUDT5
ADP-sugar pyrophosphatase

1

2

High-throughput

0.536

High

261183

GP1BA
Platelet glycoprotein Ib alpha chain

1

5

Small-scale

0.527

High

261216

CCNF
Cyclin-F

1

6

High-throughput

0.515

High

261217

MK08
Mitogen-activated protein kinase 8

1

13

Small-scale

0.515

High

261320

TX101
Testis-expressed protein 101

1

0

High-throughput

0.513

High

261336

HAUS2
HAUS augmin-like complex subunit 2

1

0

High-throughput

0.513

High

261215

MLH1
DNA mismatch repair protein Mlh1

1

1

Small-scale

0.508

High

261274

PKHO1
Pleckstrin homology domain-containing family O member 1

1

1

High-throughput

0.508

High

261331

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

12

High-throughput

0.508

High

261235

SUMO2
Small ubiquitin-related modifier 2

1

9

High-throughput

0.501

High

261243

XIAP
E3 ubiquitin-protein ligase XIAP

1

8

High-throughput

0.501

High

261312

ASB2
Ankyrin repeat and SOCS box protein 2

1

10

Small-scale

0.501

High

261174

ESR1
Estrogen receptor

1

20

High-throughput

0.500

High

261350

M3K4
Mitogen-activated protein kinase kinase kinase 4

1

7

Small-scale

0.500

High

261321

RTF2
Replication termination factor 2

1

1

High-throughput

0.489

High

261332

TANC2
Protein TANC2

1

15

High-throughput

0.489

High

224245

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.486

High

173544

NPHP1
Nephrocystin-1

1

2

Small-scale

0.481

High

261322

TRI55
Tripartite motif-containing protein 55

1

20

High-throughput

0.481

High

261337

RN216
E3 ubiquitin-protein ligase RNF216

1

1

Small-scale

0.481

High

56497

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

5

High-throughput

0.479

High

119044

LEG9
Galectin-9

1

6

High-throughput

0.479

High

129622

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

12

High-throughput

0.479

High

130661

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

5

High-throughput

0.479

High

148205

CTRO
Citron Rho-interacting kinase

1

12

High-throughput

0.479

High

209527

PRC1
Protein regulator of cytokinesis 1

1

14

High-throughput

0.479

High

232745

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

8

High-throughput

0.479

High

233105

NUPR1
Nuclear protein 1

1

5

High-throughput

0.479

High

255374

OBSL1
Obscurin-like protein 1

1

20

High-throughput

0.479

High

261165

PIAS1
E3 SUMO-protein ligase PIAS1

1

6

High-throughput

0.479

High

261166

TRI37
E3 ubiquitin-protein ligase TRIM37

1

15

High-throughput

0.479

High

261169

FMNL1
Formin-like protein 1

1

2

Small-scale

0.479

High

261176

P53
Cellular tumor antigen p53

1

5

Small-scale

0.479

High

261178

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

3

High-throughput

0.479

High

261182

NPM
Nucleophosmin

1

2

High-throughput

0.479

High

261186

BIP
Endoplasmic reticulum chaperone BiP

1

12

High-throughput

0.479

High

261187

HSP7C
Heat shock cognate 71 kDa protein

1

6

High-throughput

0.479

High

261189

CADH1
Cadherin-1

1

6

High-throughput

0.479

High

261191

ITA4
Integrin alpha-4

1

3

High-throughput

0.479

High

261193

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.479

High

261195

CEBPB
CCAAT/enhancer-binding protein beta

1

9

High-throughput

0.479

High

261197

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

5

High-throughput

0.479

High

261199

BTF3
Transcription factor BTF3

1

5

High-throughput

0.479

High

261202

GCSP
Glycine dehydrogenase

1

4

High-throughput

0.479

High

261203

CDK2
Cyclin-dependent kinase 2

1

6

High-throughput

0.479

High

261205

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

7

High-throughput

0.479

High

261206

STIP1
Stress-induced-phosphoprotein 1

1

4

High-throughput

0.479

High

261208

MCM5
DNA replication licensing factor MCM5

1

11

High-throughput

0.479

High

261209

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

2

High-throughput

0.479

High

261213

SYUA
Alpha-synuclein

1

3

High-throughput

0.479

High

261214

BRCA1
Breast cancer type 1 susceptibility protein

1

10

High-throughput

0.479

High

261218

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

12

Small-scale

0.479

High

261219

CRK
Adapter molecule crk

1

20

High-throughput

0.479

High

261220

YAP1
Transcriptional coactivator YAP1

1

15

High-throughput

0.479

High

261224

MCM2
DNA replication licensing factor MCM2

1

11

High-throughput

0.479

High

261227

CDK9
Cyclin-dependent kinase 9

1

16

High-throughput

0.479

High

261229

HDGF
Hepatoma-derived growth factor

1

1

High-throughput

0.479

High

261230

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

10

High-throughput

0.479

High

261233

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.479

High

261234

ABCE1
ATP-binding cassette sub-family E member 1

1

3

High-throughput

0.479

High

261238

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

261244

KIF23
Kinesin-like protein KIF23

1

14

High-throughput

0.479

High

261245

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

3

High-throughput

0.479

High

261247

TFCP2
Alpha-globin transcription factor CP2

1

2

High-throughput

0.479

High

261248

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

15

High-throughput

0.479

High

261249

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

1

Small-scale

0.479

High

261254

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

261256

HDAC1
Histone deacetylase 1

1

10

High-throughput

0.479

High

261259

CUL3
Cullin-3

1

11

High-throughput

0.479

High

261264

MDC1
Mediator of DNA damage checkpoint protein 1

1

15

High-throughput

0.479

High

261265

CUL7
Cullin-7

1

7

High-throughput

0.479

High

261267

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

261268

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

261269

KIF14
Kinesin-like protein KIF14

1

10

High-throughput

0.479

High

261278

RN123
E3 ubiquitin-protein ligase RNF123

1

3

High-throughput

0.479

High

261281

VIR
Protein virilizer homolog

1

3

High-throughput

0.479

High

261282

CDC73
Parafibromin

1

6

High-throughput

0.479

High

261283

RICTR
Rapamycin-insensitive companion of mTOR

1

5

High-throughput

0.479

High

261287

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

20

High-throughput

0.479

High

261292

SLN11
Schlafen family member 11

1

1

High-throughput

0.479

High

261293

ZN598
E3 ubiquitin-protein ligase ZNF598

1

3

High-throughput

0.479

High

261295

SYNPO
Synaptopodin

1

17

High-throughput

0.479

High

261297

DTX3
Probable E3 ubiquitin-protein ligase DTX3

1

4

Small-scale

0.479

High

261298

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

261300

NUDC2
NudC domain-containing protein 2

1

4

High-throughput

0.479

High

261301

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

1

High-throughput

0.479

High

261302

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

7

High-throughput

0.479

High

261308

CHM4C
Charged multivesicular body protein 4c

1

18

High-throughput

0.479

High

261309

SPDLY
Protein Spindly

1

15

High-throughput

0.479

High

261313

CK5P2
CDK5 regulatory subunit-associated protein 2

1

20

Small-scale

0.479

High

261314

RING2
E3 ubiquitin-protein ligase RING2

1

13

High-throughput

0.479

High

261316

ANM1
Protein arginine N-methyltransferase 1

1

4

High-throughput

0.479

High

261317

DUS23
Dual specificity protein phosphatase 23

1

8

High-throughput

0.479

High

261318

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

19

High-throughput

0.479

High

261319

FACD2
Fanconi anemia group D2 protein

1

9

High-throughput

0.479

High

261325

CCDC8
Coiled-coil domain-containing protein 8

1

3

High-throughput

0.479

High

261326

CHM4B
Charged multivesicular body protein 4b

1

18

High-throughput

0.479

High

261327

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

261329

ECT2
Protein ECT2

1

11

High-throughput

0.479

High

261335

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

9

High-throughput

0.479

High

261338

PIHD1
PIH1 domain-containing protein 1

1

3

High-throughput

0.479

High

261339

PD1L1
Programmed cell death 1 ligand 1

1

3

Small-scale

0.479

High

261340

HDAC6
Histone deacetylase 6

1

14

High-throughput

0.479

High

261342

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

261343

TES
Testin

1

20

High-throughput

0.479

High

261346

FZR1
Fizzy-related protein homolog

1

15

High-throughput

0.479

High

261347

UBQL1
Ubiquilin-1

1

4

High-throughput

0.479

High

261349

LOXL2
Lysyl oxidase homolog 2

1

7

High-throughput

0.479

High

261170

AGR2
Anterior gradient protein 2 homolog

1

6

High-throughput

0.470

High

261307

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

261333

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

261167

FA13A
Protein FAM13A

1

7

Small-scale

0.457

High

261286

MCAF1
Activating transcription factor 7-interacting protein 1

1

8

High-throughput

0.457

High

261185

TAU
Microtubule-associated protein tau

1

11

High-throughput

0.445

High

261210

BMI1
Polycomb complex protein BMI-1

1

14

High-throughput

0.445

High

261231

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

13

High-throughput

0.445

High

261258

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

7

High-throughput

0.445

High

261275

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

7

High-throughput

0.445

High

261284

CLC4G
C-type lectin domain family 4 member G

1

7

Small-scale

0.445

High

261304

ESR2
Estrogen receptor beta

1

19

High-throughput

0.445

High

261315

ZBT18
Zinc finger and BTB domain-containing protein 18

1

5

High-throughput

0.445

High

261323

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

11

High-throughput

0.445

High

261324

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

11

High-throughput

0.445

High

256789

T22D2
TSC22 domain family protein 2

1

3

Small-scale

0.439

High

181018

INSI1
Insulin-induced gene 1 protein

1

6

High-throughput

0.437

High

231910

KDM1A
Lysine-specific histone demethylase 1A

1

2

High-throughput

0.437

High

261168

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.437

High

261172

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.437

High

261192

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.437

High

261204

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.437

High

261211

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

261236

WDR5
WD repeat-containing protein 5

1

15

High-throughput

0.437

High

261271

EZH2
Histone-lysine N-methyltransferase EZH2

1

7

High-throughput

0.437

High

261273

FBX43
F-box only protein 43

1

2

Small-scale

0.437

High

261279

DCA15
DDB1- and CUL4-associated factor 15

1

1

High-throughput

0.437

High

261280

ATG9B
Autophagy-related protein 9B

1

1

Small-scale

0.437

High

261285

LRC31
Leucine-rich repeat-containing protein 31

1

2

High-throughput

0.437

High

261290

KCTD9
BTB/POZ domain-containing protein KCTD9

1

16

High-throughput

0.437

High

261291

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.437

High

261294

MGDP1
Magnesium-dependent phosphatase 1

1

3

High-throughput

0.437

High

261296

SIR6
NAD-dependent protein deacylase sirtuin-6

1

9

Small-scale

0.437

High

261305

TF3B
Transcription factor IIIB 90 kDa subunit

1

1

Small-scale

0.437

High

261306

PF21A
PHD finger protein 21A

1

8

High-throughput

0.437

High

261330

WDR76
WD repeat-containing protein 76

1

19

High-throughput

0.437

High

261348

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

261200

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

High-throughput

0.426

High

261194

TSHR
Thyrotropin receptor

1

11

Small-scale

0.408

High

261253

CTBP1
C-terminal-binding protein 1

1

5

High-throughput

0.407

High

261276

LITD1
LINE-1 type transposase domain-containing protein 1

1

1

High-throughput

0.407

High

261266

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024