Protein: 2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A subunit A isoform PR65-beta) (PP2A subunit A isoform R1-beta)

Gene: 2AAB, PPP2R1B
Organism: Homo sapiens
Interactions: 161
UniProt ID: P30154

Gene Ontology (top 5):
GO:0000159 - protein phosphatase type 2A complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019888 - protein phosphatase regulator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

672402

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

9

20

Small-scale

0.979

High

672399

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

7

20

Small-scale

0.972

High

672002

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

7

4

Small-scale

0.962

High

215199

STRN
Striatin

5

16

Small-scale

0.932

High

672425

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

5

20

Small-scale

0.931

High

672413

STRN3
Striatin-3

5

20

Small-scale

0.930

High

672422

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

4

20

Small-scale

0.900

High

131550

STK25
Serine/threonine-protein kinase 25

3

15

High-throughput

0.871

High

672501

STK24
Serine/threonine-protein kinase 24

3

17

High-throughput

0.871

High

672407

P2R3A
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha

3

9

Small-scale

0.861

High

672428

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

3

20

Small-scale

0.858

High

672415

2A5G
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

3

20

Small-scale

0.839

High

672426

2A5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform

2

20

Small-scale

0.789

High

672400

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

6

10

Small-scale

0.737

High

672495

2ABG
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

6

10

High-throughput

0.736

High

672499

P2R3B
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta

1

9

Small-scale

0.724

High

672434

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

4

10

High-throughput

0.706

High

56512

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

4

13

High-throughput

0.694

High

414763

CDK1
Cyclin-dependent kinase 1

1

3

Small-scale

0.691

High

515346

CDK4
Cyclin-dependent kinase 4

1

5

Small-scale

0.691

High

672395

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

20

High-throughput

0.691

High

672436

PKN3
Serine/threonine-protein kinase N3

1

2

High-throughput

0.691

High

672452

PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

1

5

High-throughput

0.691

High

672483

STK26
Serine/threonine-protein kinase 26

1

15

High-throughput

0.691

High

672494

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

6

High-throughput

0.691

High

672404

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

3

10

High-throughput

0.681

High

208893

FOXS1
Forkhead box protein S1

3

11

High-throughput

0.667

High

672449

ZN114
Zinc finger protein 114

3

5

High-throughput

0.667

High

672467

IER2
Immediate early response gene 2 protein

3

3

High-throughput

0.667

High

672480

SRTD4
SERTA domain-containing protein 4

3

1

High-throughput

0.667

High

672486

ZN219
Zinc finger protein 219

3

2

High-throughput

0.667

High

672379

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

4

High-throughput

0.656

High

528622

CFTR
Cystic fibrosis transmembrane conductance regulator

3

5

High-throughput

0.656

High

672431

SGO2
Shugoshin 2

3

1

Small-scale

0.650

High

672392

WNT3A
Protein Wnt-3a

3

0

High-throughput

0.638

High

672412

FOXD4
Forkhead box protein D4

2

11

High-throughput

0.628

High

672441

ZN550
Zinc finger protein 550

2

4

High-throughput

0.628

High

672470

CDCA4
Cell division cycle-associated protein 4

2

5

High-throughput

0.628

High

672478

ZN331
Zinc finger protein 331

2

2

High-throughput

0.628

High

672482

TBCC1
TBCC domain-containing protein 1

2

4

High-throughput

0.628

High

166536

DCLK1
Serine/threonine-protein kinase DCLK1

1

9

High-throughput

0.618

High

672461

PSKH2
Serine/threonine-protein kinase H2

1

8

High-throughput

0.618

High

672390

DAPK1
Death-associated protein kinase 1

1

11

Small-scale

0.618

High

672414

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

9

Small-scale

0.618

High

672465

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

7

High-throughput

0.618

High

672447

FA43A
Protein FAM43A

3

1

High-throughput

0.609

High

672493

T3JAM
TRAF3-interacting JNK-activating modulator

3

7

High-throughput

0.604

High

672492

TRI35
E3 ubiquitin-protein ligase TRIM35

2

0

High-throughput

0.602

High

318928

CEP43
Centrosomal protein 43

2

1

Small-scale

0.601

High

672466

SIKE1
Suppressor of IKBKE 1

2

3

High-throughput

0.601

High

672427

CRY1
Cryptochrome-1

2

4

High-throughput

0.586

High

672491

INT6
Integrator complex subunit 6

2

3

Small-scale

0.584

High

672444

ULK2
Serine/threonine-protein kinase ULK2

1

13

High-throughput

0.575

High

672472

SIK2
Serine/threonine-protein kinase SIK2

1

11

Small-scale

0.575

High

672479

STRN4
Striatin-4

1

18

High-throughput

0.575

High

672469

PRR14
Proline-rich protein 14

2

5

High-throughput

0.574

High

672454

BAD
Bcl2-associated agonist of cell death

2

1

High-throughput

0.571

High

672496

PHOCN
MOB-like protein phocein

1

6

High-throughput

0.554

High

181500

CLOCK
Circadian locomoter output cycles protein kaput

1

5

High-throughput

0.552

High

672445

UNC5B
Netrin receptor UNC5B

1

2

Small-scale

0.552

High

66645

ZN785
Zinc finger protein 785

1

6

High-throughput

0.536

High

123861

SPT5H
Transcription elongation factor SPT5

1

2

High-throughput

0.536

High

444844

ANXA5
Annexin A5

1

1

Small-scale

0.536

High

471561

TFPT
TCF3 fusion partner

1

1

High-throughput

0.536

High

506364

RALA
Ras-related protein Ral-A

1

8

Small-scale

0.536

High

508354

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.536

High

531044

EF2
Elongation factor 2

1

6

Small-scale

0.536

High

583653

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

1

High-throughput

0.536

High

627189

MCM3
DNA replication licensing factor MCM3

1

4

Small-scale

0.536

High

672380

PRDX2
Peroxiredoxin-2

1

4

Small-scale

0.536

High

672386

KSYK
Tyrosine-protein kinase SYK

1

11

High-throughput

0.536

High

672387

RAB7A
Ras-related protein Rab-7a

1

5

Small-scale

0.536

High

672391

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

1

High-throughput

0.536

High

672398

RB11A
Ras-related protein Rab-11A

1

2

Small-scale

0.536

High

672401

DYL1
Dynein light chain 1, cytoplasmic

1

3

High-throughput

0.536

High

672408

PRDX1
Peroxiredoxin-1

1

4

Small-scale

0.536

High

672409

SSRP1
FACT complex subunit SSRP1

1

7

High-throughput

0.536

High

672410

NCBP1
Nuclear cap-binding protein subunit 1

1

3

High-throughput

0.536

High

672417

HDAC1
Histone deacetylase 1

1

7

Small-scale

0.536

High

672418

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.536

High

672419

SRTD2
SERTA domain-containing protein 2

1

3

High-throughput

0.536

High

672429

FX4L6
Forkhead box protein D4-like 6

1

11

High-throughput

0.536

High

672432

SGO1
Shugoshin 1

1

1

High-throughput

0.536

High

672438

NPSR1
Neuropeptide S receptor

1

3

High-throughput

0.536

High

672450

COP1
E3 ubiquitin-protein ligase COP1

1

8

High-throughput

0.536

High

672456

PBIR1
PPP2R1A-PPP2R2A-interacting phosphatase regulator 1

1

2

High-throughput

0.536

High

672460

CEP19
Centrosomal protein of 19 kDa

1

1

High-throughput

0.536

High

672463

PARK7
Parkinson disease protein 7

1

1

Small-scale

0.536

High

672464

NPAS1
Neuronal PAS domain-containing protein 1

1

5

High-throughput

0.536

High

672468

PDC10
Programmed cell death protein 10

1

1

High-throughput

0.536

High

672474

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

1

High-throughput

0.536

High

672477

RAB18
Ras-related protein Rab-18

1

3

Small-scale

0.536

High

672481

FGOP2
FGFR1 oncogene partner 2

1

3

High-throughput

0.536

High

672484

CT2NL
CTTNBP2 N-terminal-like protein

1

4

High-throughput

0.536

High

672488

SRTD1
SERTA domain-containing protein 1

1

1

High-throughput

0.536

High

672487

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.515

High

157871

KLF11
Krueppel-like factor 11

1

5

High-throughput

0.515

High

672396

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

672388

RORG
Nuclear receptor ROR-gamma

1

3

High-throughput

0.508

High

672403

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.508

High

174649

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

6

High-throughput

0.501

High

475380

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

7

High-throughput

0.501

High

672381

NUP62
Nuclear pore glycoprotein p62

1

7

Small-scale

0.501

High

257923

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.493

High

623600

IBP5
Insulin-like growth factor-binding protein 5

1

1

High-throughput

0.489

High

672385

CNDD3
Condensin-2 complex subunit D3

1

1

High-throughput

0.489

High

672411

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

2

High-throughput

0.489

High

672423

SLMAP
Sarcolemmal membrane-associated protein

1

6

High-throughput

0.489

High

672424

P2RY6
P2Y purinoceptor 6

1

13

High-throughput

0.489

High

672473

CA021
Uncharacterized protein C1orf21

1

1

High-throughput

0.489

High

672497

CCDC9
Coiled-coil domain-containing protein 9

1

1

High-throughput

0.489

High

672500

GPR45
Probable G-protein coupled receptor 45

1

6

High-throughput

0.489

High

672430

CRY2
Cryptochrome-2

1

4

High-throughput

0.481

High

672471

BHE41
Class E basic helix-loop-helix protein 41

1

2

High-throughput

0.481

High

672490

FBW1B
F-box/WD repeat-containing protein 11

1

7

High-throughput

0.481

High

206804

FOXO3
Forkhead box protein O3

1

5

Small-scale

0.479

High

209701

PRC1
Protein regulator of cytokinesis 1

1

3

High-throughput

0.479

High

238365

JAK2
Tyrosine-protein kinase JAK2

1

9

Small-scale

0.479

High

294423

RECQ4
ATP-dependent DNA helicase Q4

1

7

High-throughput

0.479

High

337995

EGFR
Epidermal growth factor receptor

1

10

High-throughput

0.479

High

503511

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

507873

FGFR1
Fibroblast growth factor receptor 1

1

10

Small-scale

0.479

High

599619

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

6

High-throughput

0.479

High

672382

SYUA
Alpha-synuclein

1

2

High-throughput

0.479

High

672389

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

6

High-throughput

0.479

High

672393

FBXW4
F-box/WD repeat-containing protein 4

1

9

Small-scale

0.479

High

672394

ZN445
Zinc finger protein 445

1

2

High-throughput

0.479

High

672397

MAX
Protein max

1

7

Small-scale

0.479

High

672405

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

6

High-throughput

0.479

High

672406

CAV1
Caveolin-1

1

2

Small-scale

0.479

High

672416

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

5

High-throughput

0.479

High

672420

TRI14
Tripartite motif-containing protein 14

1

5

High-throughput

0.479

High

672435

INT3
Integrator complex subunit 3

1

1

High-throughput

0.479

High

672437

INT5
Integrator complex subunit 5

1

1

High-throughput

0.479

High

672439

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

672446

INT1
Integrator complex subunit 1

1

1

High-throughput

0.479

High

672448

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.479

High

672451

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

1

Small-scale

0.479

High

672457

DYL2
Dynein light chain 2, cytoplasmic

1

3

High-throughput

0.479

High

672458

TNIP3
TNFAIP3-interacting protein 3

1

1

High-throughput

0.479

High

672462

RUFY1
RUN and FYVE domain-containing protein 1

1

3

High-throughput

0.479

High

672475

EGLN3
Prolyl hydroxylase EGLN3

1

4

High-throughput

0.479

High

672498

DCAF1
DDB1- and CUL4-associated factor 1

1

9

Small-scale

0.479

High

672502

NEMO
NF-kappa-B essential modulator

1

3

Small-scale

0.479

High

672440

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

4

High-throughput

0.470

High

456093

DPOLA
DNA polymerase alpha catalytic subunit

1

0

Small-scale

0.458

High

672383

STAT3
Signal transducer and activator of transcription 3

1

0

Small-scale

0.458

High

146460

BHE40
Class E basic helix-loop-helix protein 40

1

2

High-throughput

0.457

High

499559

CH60
60 kDa heat shock protein, mitochondrial

1

2

Small-scale

0.445

High

672384

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

4

High-throughput

0.445

High

672421

ESPL1
Separin

1

2

Small-scale

0.445

High

672433

STRP1
Striatin-interacting protein 1

1

4

High-throughput

0.445

High

672455

ZN566
Zinc finger protein 566

1

3

High-throughput

0.445

High

672476

DOCK5
Dedicator of cytokinesis protein 5

1

2

High-throughput

0.445

High

672485

DEC1
Deleted in esophageal cancer 1

1

1

High-throughput

0.439

High

672459

EP400
E1A-binding protein p400

1

1

Small-scale

0.437

High

672443

ZN695
Zinc finger protein 695

1

0

High-throughput

0.426

High

672489

ZN223
Zinc finger protein 223

1

0

High-throughput

0.426

High

672453

CTTB2
Cortactin-binding protein 2

1

15

High-throughput

0.407

High

672442

TAFA3
Chemokine-like protein TAFA-3

2

0

High-throughput

0.328

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024