Protein: LMTK1
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)

Gene: LMTK1, AATK
Organism: Homo sapiens
Interactions: 189
UniProt ID: Q6ZMQ8

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0004713 - protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0007420 - brain development
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1168432

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

2

13

Small-scale

0.757

High

960298

CDK5
Cyclin-dependent kinase 5

1

20

Small-scale

0.747

High

383861

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

20

High-throughput

0.743

High

309494

MTMR5
Myotubularin-related protein 5

1

20

High-throughput

0.698

High

665906

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

20

High-throughput

0.698

High

985980

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

High-throughput

0.698

High

1069852

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

20

High-throughput

0.698

High

737881

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

4

9

Small-scale

0.637

High

719351

PTN7
Tyrosine-protein phosphatase non-receptor type 7

1

20

High-throughput

0.625

High

890714

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

20

High-throughput

0.625

High

983495

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

20

High-throughput

0.625

High

1167717

TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

1

20

High-throughput

0.625

High

1168408

PTN18
Tyrosine-protein phosphatase non-receptor type 18

1

20

High-throughput

0.625

High

532149

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

2

6

High-throughput

0.618

High

1168423

ATD3A
ATPase family AAA domain-containing protein 3A

2

13

High-throughput

0.618

High

171309

EPHB6
Ephrin type-B receptor 6

1

19

High-throughput

0.618

High

201354

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

20

High-throughput

0.618

High

320537

OXSR1
Serine/threonine-protein kinase OSR1

1

20

High-throughput

0.618

High

414966

CDK1
Cyclin-dependent kinase 1

1

20

High-throughput

0.618

High

640120

MOES
Moesin

1

20

High-throughput

0.618

High

905979

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

3

9

Small-scale

0.615

High

719736

RADI
Radixin

1

20

High-throughput

0.578

High

1067681

CD5R1
Cyclin-dependent kinase 5 activator 1

1

4

Small-scale

0.573

High

906508

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

2

9

High-throughput

0.565

High

1077891

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

2

12

High-throughput

0.561

High

973948

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

2

20

High-throughput

0.558

High

1117000

PTN20
Tyrosine-protein phosphatase non-receptor type 20

1

20

High-throughput

0.555

High

557719

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.553

High

1073921

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

20

High-throughput

0.553

High

1078847

ITSN1
Intersectin-1

1

20

High-throughput

0.553

High

1168386

MILK1
MICAL-like protein 1

1

20

High-throughput

0.553

High

1168389

EHBP1
EH domain-binding protein 1

1

20

High-throughput

0.553

High

1168397

SH3K1
SH3 domain-containing kinase-binding protein 1

1

20

High-throughput

0.553

High

1168427

ITSN2
Intersectin-2

1

20

High-throughput

0.553

High

273446

PPM1B
Protein phosphatase 1B

1

12

High-throughput

0.541

High

728626

PPM1A
Protein phosphatase 1A

1

11

High-throughput

0.541

High

829453

PPM1F
Protein phosphatase 1F

1

20

High-throughput

0.541

High

1168399

MTMR8
Myotubularin-related protein 8

1

18

High-throughput

0.541

High

1168406

MTMR9
Myotubularin-related protein 9

1

18

High-throughput

0.541

High

1168424

MTMRA
Myotubularin-related protein 10

1

18

High-throughput

0.541

High

1168442

MTMR6
Myotubularin-related protein 6

1

18

High-throughput

0.541

High

240599

DPM1
Dolichol-phosphate mannosyltransferase subunit 1

1

7

High-throughput

0.536

High

274564

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

19

High-throughput

0.536

High

320873

HS74L
Heat shock 70 kDa protein 4L

1

20

High-throughput

0.536

High

681496

DNJA1
DnaJ homolog subfamily A member 1

1

20

High-throughput

0.536

High

932217

ACTC
Actin, alpha cardiac muscle 1

1

9

High-throughput

0.536

High

1168393

HS105
Heat shock protein 105 kDa

1

20

High-throughput

0.536

High

1168400

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

20

High-throughput

0.536

High

431978

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.500

High

959241

S25A3
Solute carrier family 25 member 3

1

17

High-throughput

0.500

High

966719

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

19

High-throughput

0.500

High

1168411

NTPCR
Cancer-related nucleoside-triphosphatase

1

10

High-throughput

0.500

High

56538

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

20

High-throughput

0.494

High

118570

EYA2
Eyes absent homolog 2

1

7

High-throughput

0.494

High

304979

DUS14
Dual specificity protein phosphatase 14

1

20

High-throughput

0.494

High

318651

EYA4
Eyes absent homolog 4

1

14

High-throughput

0.494

High

557553

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

14

High-throughput

0.494

High

659292

DUS1
Dual specificity protein phosphatase 1

1

20

High-throughput

0.494

High

673492

MPIP2
M-phase inducer phosphatase 2

1

1

High-throughput

0.494

High

673759

BKRB2
B2 bradykinin receptor

1

1

High-throughput

0.494

High

994089

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

15

High-throughput

0.494

High

1086145

DUS5
Dual specificity protein phosphatase 5

1

20

High-throughput

0.494

High

1088015

DUS6
Dual specificity protein phosphatase 6

1

20

High-throughput

0.494

High

1148509

DUS29
Dual specificity phosphatase 29

1

20

High-throughput

0.494

High

1168387

PPM1K
Protein phosphatase Mn(2+)-dependent 1K

1

20

High-throughput

0.494

High

1168392

STYX
Serine/threonine/tyrosine-interacting protein

1

20

High-throughput

0.494

High

1168402

PPM1M
Protein phosphatase 1M

1

13

High-throughput

0.494

High

1168409

DUS9
Dual specificity protein phosphatase 9

1

20

High-throughput

0.494

High

1168415

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

20

High-throughput

0.494

High

1168441

CC14A
Dual specificity protein phosphatase CDC14A

1

20

High-throughput

0.494

High

130529

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

8

High-throughput

0.489

High

388531

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.489

High

858278

TXTP
Tricarboxylate transport protein, mitochondrial

1

20

High-throughput

0.489

High

1070840

RCN1
Reticulocalbin-1

1

8

High-throughput

0.489

High

1168418

GHC1
Mitochondrial glutamate carrier 1

1

20

High-throughput

0.489

High

1168435

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

19

High-throughput

0.489

High

1168437

FBW1B
F-box/WD repeat-containing protein 11

1

8

High-throughput

0.489

High

61393

CNOT1
CCR4-NOT transcription complex subunit 1

1

1

High-throughput

0.479

High

119984

AP3B1
AP-3 complex subunit beta-1

1

20

High-throughput

0.479

High

208601

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

7

High-throughput

0.479

High

229426

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

11

High-throughput

0.479

High

229870

KIF5C
Kinesin heavy chain isoform 5C

1

18

High-throughput

0.479

High

254909

CPNE3
Copine-3

1

8

High-throughput

0.479

High

281307

RL1D1
Ribosomal L1 domain-containing protein 1

1

3

High-throughput

0.479

High

302297

SC31A
Protein transport protein Sec31A

1

20

High-throughput

0.479

High

321578

AP2A1
AP-2 complex subunit alpha-1

1

20

High-throughput

0.479

High

398721

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

10

High-throughput

0.479

High

451915

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

6

High-throughput

0.479

High

574705

ARF4
ADP-ribosylation factor 4

1

15

High-throughput

0.479

High

597674

VATB2
V-type proton ATPase subunit B, brain isoform

1

7

High-throughput

0.479

High

750855

VATA
V-type proton ATPase catalytic subunit A

1

10

High-throughput

0.479

High

785549

ACTY
Beta-centractin

1

11

High-throughput

0.479

High

787931

EPS15
Epidermal growth factor receptor substrate 15

1

20

High-throughput

0.479

High

793002

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

18

High-throughput

0.479

High

814475

SYQ
Glutamine--tRNA ligase

1

5

High-throughput

0.479

High

841993

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

20

High-throughput

0.479

High

844115

FXR2
RNA-binding protein FXR2

1

7

High-throughput

0.479

High

896471

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

8

High-throughput

0.479

High

925919

AP2B1
AP-2 complex subunit beta

1

20

High-throughput

0.479

High

944296

PRKDC
DNA-dependent protein kinase catalytic subunit

1

18

High-throughput

0.479

High

988960

FMR1
Fragile X messenger ribonucleoprotein 1

1

7

High-throughput

0.479

High

1051332

DCTN1
Dynactin subunit 1

1

19

High-throughput

0.479

High

1051583

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

6

High-throughput

0.479

High

1057890

DIP2A
Disco-interacting protein 2 homolog A

1

20

High-throughput

0.479

High

1065531

SYK
Lysine--tRNA ligase

1

8

High-throughput

0.479

High

1066293

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.479

High

1071110

RBP1
RalA-binding protein 1

1

20

High-throughput

0.479

High

1158612

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

20

High-throughput

0.479

High

1164812

AFTIN
Aftiphilin

1

1

High-throughput

0.479

High

1168383

GCC2
GRIP and coiled-coil domain-containing protein 2

1

19

High-throughput

0.479

High

1168384

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.479

High

1168385

NUP93
Nuclear pore complex protein Nup93

1

7

High-throughput

0.479

High

1168390

NBEA
Neurobeachin

1

20

High-throughput

0.479

High

1168394

CNOT9
CCR4-NOT transcription complex subunit 9

1

1

High-throughput

0.479

High

1168395

SYAP1
Synapse-associated protein 1

1

6

High-throughput

0.479

High

1168396

EXOC4
Exocyst complex component 4

1

3

High-throughput

0.479

High

1168401

DDX27
Probable ATP-dependent RNA helicase DDX27

1

19

High-throughput

0.479

High

1168414

KLC2
Kinesin light chain 2

1

15

High-throughput

0.479

High

1168416

PDCL3
Phosducin-like protein 3

1

4

High-throughput

0.479

High

1168420

CNO10
CCR4-NOT transcription complex subunit 10

1

2

High-throughput

0.479

High

1168421

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

4

High-throughput

0.479

High

1168422

FANCI
Fanconi anemia group I protein

1

7

High-throughput

0.479

High

1168430

ANFY1
Rabankyrin-5

1

20

High-throughput

0.479

High

1168433

BAZ1B
Tyrosine-protein kinase BAZ1B

1

16

High-throughput

0.479

High

1168440

SYNRG
Synergin gamma

1

1

High-throughput

0.479

High

1168447

HYOU1
Hypoxia up-regulated protein 1

1

20

High-throughput

0.479

High

1168448

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

8

High-throughput

0.479

High

278630

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.458

High

376472

APOB
Apolipoprotein B-100

1

1

High-throughput

0.457

High

1041058

CUL1
Cullin-1

1

14

High-throughput

0.457

High

1082838

CDC37
Hsp90 co-chaperone Cdc37

1

20

High-throughput

0.457

High

1168378

ACD11
Acyl-CoA dehydrogenase family member 11

1

5

High-throughput

0.457

High

1168380

FBX11
F-box only protein 11

1

1

High-throughput

0.457

High

1168431

DIC
Mitochondrial dicarboxylate carrier

1

19

High-throughput

0.457

High

1168444

FBW1A
F-box/WD repeat-containing protein 1A

1

9

High-throughput

0.457

High

241769

CCD22
Coiled-coil domain-containing protein 22

1

20

High-throughput

0.437

High

246084

PP1RB
E3 ubiquitin-protein ligase PPP1R11

1

1

High-throughput

0.437

High

337020

PNPH
Purine nucleoside phosphorylase

1

2

High-throughput

0.437

High

386959

P53
Cellular tumor antigen p53

1

9

High-throughput

0.437

High

531873

PDIA4
Protein disulfide-isomerase A4

1

20

High-throughput

0.437

High

782726

IPP2
Protein phosphatase inhibitor 2

1

1

High-throughput

0.437

High

819708

TPC10
Trafficking protein particle complex subunit 10

1

1

High-throughput

0.437

High

823424

PAXI
Paxillin

1

20

High-throughput

0.437

High

839619

SERPH
Serpin H1

1

13

High-throughput

0.437

High

914541

ERF1
Eukaryotic peptide chain release factor subunit 1

1

4

High-throughput

0.437

High

947591

RT05
Small ribosomal subunit protein uS5m

1

5

High-throughput

0.437

High

994978

GOGA2
Golgin subfamily A member 2

1

20

High-throughput

0.437

High

1014036

AP1B1
AP-1 complex subunit beta-1

1

20

High-throughput

0.437

High

1015856

WASC5
WASH complex subunit 5

1

4

High-throughput

0.437

High

1021762

PP1R8
Nuclear inhibitor of protein phosphatase 1

1

9

High-throughput

0.437

High

1044627

FHL3
Four and a half LIM domains protein 3

1

20

High-throughput

0.437

High

1063891

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.437

High

1070128

RABE1
Rab GTPase-binding effector protein 1

1

13

High-throughput

0.437

High

1075840

TRIPB
Thyroid receptor-interacting protein 11

1

20

High-throughput

0.437

High

1101814

WASC4
WASH complex subunit 4

1

4

High-throughput

0.437

High

1113946

RABL6
Rab-like protein 6

1

2

High-throughput

0.437

High

1145057

WAC2A
WASH complex subunit 2A

1

4

High-throughput

0.437

High

1145596

F91A1
Protein FAM91A1

1

2

High-throughput

0.437

High

1151764

RGPA1
Ral GTPase-activating protein subunit alpha-1

1

4

High-throughput

0.437

High

1167451

RFIP1
Rab11 family-interacting protein 1

1

20

High-throughput

0.437

High

1168377

RINL
Ras and Rab interactor-like protein

1

11

High-throughput

0.437

High

1168379

ZFY16
Zinc finger FYVE domain-containing protein 16

1

20

High-throughput

0.437

High

1168381

TPPC5
Trafficking protein particle complex subunit 5

1

1

High-throughput

0.437

High

1168382

AHNK2
Protein AHNAK2

1

13

High-throughput

0.437

High

1168388

ENAH
Protein enabled homolog

1

20

High-throughput

0.437

High

1168391

NEDD1
Protein NEDD1

1

10

High-throughput

0.437

High

1168398

AP2M1
AP-2 complex subunit mu

1

13

High-throughput

0.437

High

1168404

RBM14
RNA-binding protein 14

1

16

High-throughput

0.437

High

1168405

TPPC9
Trafficking protein particle complex subunit 9

1

4

High-throughput

0.437

High

1168407

NEB2
Neurabin-2

1

20

High-throughput

0.437

High

1168410

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

11

High-throughput

0.437

High

1168412

RFIP5
Rab11 family-interacting protein 5

1

20

High-throughput

0.437

High

1168413

EGLN1
Egl nine homolog 1

1

5

High-throughput

0.437

High

1168419

PPIP2
Proline-serine-threonine phosphatase-interacting protein 2

1

20

High-throughput

0.437

High

1168425

ARP10
Actin-related protein 10

1

10

High-throughput

0.437

High

1168426

GGA3
ADP-ribosylation factor-binding protein GGA3

1

20

High-throughput

0.437

High

1168428

RELCH
RAB11-binding protein RELCH

1

1

High-throughput

0.437

High

1168429

F135A
Protein FAM135A

1

7

High-throughput

0.437

High

1168434

HOOK1
Protein Hook homolog 1

1

20

High-throughput

0.437

High

1168436

DCTN4
Dynactin subunit 4

1

1

High-throughput

0.437

High

1168438

MRT4
mRNA turnover protein 4 homolog

1

5

High-throughput

0.437

High

1168439

NEB1
Neurabin-1

1

20

High-throughput

0.437

High

1168443

TPPC4
Trafficking protein particle complex subunit 4

1

2

High-throughput

0.437

High

1168445

SBDS
Ribosome maturation protein SBDS

1

2

High-throughput

0.437

High

1168446

RBGP1
Rab GTPase-activating protein 1

1

20

High-throughput

0.437

High

1168403

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.316

High

847288

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.279

Low

126700

DCTN6
Dynactin subunit 6

1

0

High-throughput

0.249

Low

1168417

WDCP
WD repeat and coiled-coil-containing protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024