Protein: SMCA1
Probable global transcription activator SNF2L1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA1) (Nucleosome-remodeling factor subunit SNF2L) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1)

Gene: SMCA1, SMARCA1
Organism: Homo sapiens
Interactions: 179
UniProt ID: P28370

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0004386 - helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

658751

BAZ1B
Tyrosine-protein kinase BAZ1B

4

20

High-throughput

0.892

High

658647

H31
Histone H3.1

4

20

Small-scale

0.873

High

469951

H2AZ
Histone H2A.Z

2

20

High-throughput

0.789

High

658722

RSF1
Remodeling and spacing factor 1

2

20

Small-scale

0.789

High

658660

CHD3
Chromodomain-helicase-DNA-binding protein 3

2

15

High-throughput

0.754

High

658672

CHD4
Chromodomain-helicase-DNA-binding protein 4

2

14

High-throughput

0.754

High

658658

RBBP4
Histone-binding protein RBBP4

4

20

Small-scale

0.702

High

658682

RBBP7
Histone-binding protein RBBP7

4

20

Small-scale

0.699

High

658659

BPTF
Nucleosome-remodeling factor subunit BPTF

4

20

Small-scale

0.699

High

470278

H2A1
Histone H2A type 1

1

20

High-throughput

0.691

High

658650

CBX1
Chromobox protein homolog 1

1

20

High-throughput

0.691

High

658684

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.691

High

658742

BAZ1A
Bromodomain adjacent to zinc finger domain protein 1A

1

20

High-throughput

0.691

High

658701

BAP18
Chromatin complexes subunit BAP18

4

4

High-throughput

0.683

High

658734

DEFI6
Differentially expressed in FDCP 6 homolog

3

5

High-throughput

0.667

High

455119

PARP1
Poly [ADP-ribose] polymerase 1

3

20

Small-scale

0.656

High

658726

CECR2
Chromatin remodeling regulator CECR2

3

20

Small-scale

0.656

High

658681

EZH2
Histone-lysine N-methyltransferase EZH2

3

20

High-throughput

0.640

High

658740

DPOE3
DNA polymerase epsilon subunit 3

2

4

High-throughput

0.628

High

658727

DPY30
Protein dpy-30 homolog

2

2

Small-scale

0.618

High

229318

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

17

High-throughput

0.618

High

260763

H2AY
Core histone macro-H2A.1

1

20

High-throughput

0.618

High

294411

RECQ4
ATP-dependent DNA helicase Q4

1

17

High-throughput

0.618

High

555306

H2AX
Histone H2AX

1

20

High-throughput

0.618

High

658641

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.618

High

658646

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.618

High

658648

RED1
Double-stranded RNA-specific editase 1

1

20

High-throughput

0.618

High

658651

H33
Histone H3.3

1

20

High-throughput

0.618

High

658654

ERCC6
DNA excision repair protein ERCC-6

1

17

Small-scale

0.618

High

658667

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.618

High

658674

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

17

High-throughput

0.618

High

658748

HMGX4
HMG domain-containing protein 4

2

20

High-throughput

0.611

High

267906

EED
Polycomb protein EED

2

20

High-throughput

0.584

High

607786

USF1
Upstream stimulatory factor 1

2

20

Small-scale

0.584

High

658702

DDX60
Probable ATP-dependent RNA helicase DDX60

1

17

High-throughput

0.575

High

522800

SRC
Proto-oncogene tyrosine-protein kinase Src

2

6

High-throughput

0.571

High

592116

RAB5A
Ras-related protein Rab-5A

2

4

High-throughput

0.571

High

322219

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

19

High-throughput

0.553

High

658694

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.553

High

71074

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

13

High-throughput

0.536

High

126432

FOXE1
Forkhead box protein E1

1

20

High-throughput

0.536

High

149823

RFXK
DNA-binding protein RFXANK

1

7

High-throughput

0.536

High

307508

EPN2
Epsin-2

1

3

High-throughput

0.536

High

324741

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

14

High-throughput

0.536

High

426578

H10
Histone H1.0

1

3

High-throughput

0.536

High

449557

HMGB1
High mobility group protein B1

1

20

High-throughput

0.536

High

508351

TOP1
DNA topoisomerase 1

1

8

High-throughput

0.536

High

557616

NCK1
SH2/SH3 adapter protein NCK1

1

9

High-throughput

0.536

High

564808

HMGA1
High mobility group protein HMG-I/HMG-Y

1

4

High-throughput

0.536

High

658637

RS19
Small ribosomal subunit protein eS19

1

7

High-throughput

0.536

High

658638

MAGA3
Melanoma-associated antigen 3

1

5

High-throughput

0.536

High

658643

IMA5
Importin subunit alpha-5

1

20

High-throughput

0.536

High

658644

FOXG1
Forkhead box protein G1

1

20

High-throughput

0.536

High

658645

MAX
Protein max

1

20

High-throughput

0.536

High

658649

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

3

High-throughput

0.536

High

658652

FOXK2
Forkhead box protein K2

1

20

High-throughput

0.536

High

658653

TIE2
Angiopoietin-1 receptor

1

4

High-throughput

0.536

High

658655

SUH
Recombining binding protein suppressor of hairless

1

11

High-throughput

0.536

High

658657

SSRP1
FACT complex subunit SSRP1

1

20

High-throughput

0.536

High

658661

FOXC1
Forkhead box protein C1

1

20

High-throughput

0.536

High

658662

FOXL1
Forkhead box protein L1

1

20

High-throughput

0.536

High

658663

MYO1E
Unconventional myosin-Ie

1

9

High-throughput

0.536

High

658664

PRDM2
PR domain zinc finger protein 2

1

6

High-throughput

0.536

High

658673

NUMA1
Nuclear mitotic apparatus protein 1

1

10

High-throughput

0.536

High

658679

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

658680

TEAD2
Transcriptional enhancer factor TEF-4

1

7

High-throughput

0.536

High

658692

IFIX
Pyrin and HIN domain-containing protein 1

1

10

High-throughput

0.536

High

658696

POGZ
Pogo transposable element with ZNF domain

1

1

High-throughput

0.536

High

658704

RYBP
RING1 and YY1-binding protein

1

3

High-throughput

0.536

High

658709

NF2IP
NFATC2-interacting protein

1

1

High-throughput

0.536

High

658724

VRK1
Serine/threonine-protein kinase VRK1

1

4

High-throughput

0.536

High

658728

FOXQ1
Forkhead box protein Q1

1

20

High-throughput

0.536

High

658732

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

2

High-throughput

0.536

High

658741

CHRC1
Chromatin accessibility complex protein 1

1

3

High-throughput

0.536

High

658745

FOXJ2
Forkhead box protein J2

1

20

High-throughput

0.536

High

658686

INAVA
Innate immunity activator protein

1

0

High-throughput

0.513

High

658697

ZN467
Zinc finger protein 467

1

0

High-throughput

0.513

High

658678

EEA1
Early endosome antigen 1

1

20

High-throughput

0.489

High

658707

NECP1
Adaptin ear-binding coat-associated protein 1

1

1

High-throughput

0.489

High

658749

CTNA3
Catenin alpha-3

1

1

High-throughput

0.489

High

658752

KLH20
Kelch-like protein 20

1

2

High-throughput

0.489

High

63968

DUXA
Double homeobox protein A

1

19

High-throughput

0.479

High

125173

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

High-throughput

0.479

High

146802

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

9

High-throughput

0.479

High

148426

CTRO
Citron Rho-interacting kinase

1

9

High-throughput

0.479

High

158745

HAT1
Histone acetyltransferase type B catalytic subunit

1

2

High-throughput

0.479

High

165631

SET1A
Histone-lysine N-methyltransferase SETD1A

1

20

Small-scale

0.479

High

179555

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

10

High-throughput

0.479

High

197950

PHF1
PHD finger protein 1

1

9

High-throughput

0.479

High

209697

PRC1
Protein regulator of cytokinesis 1

1

4

High-throughput

0.479

High

233233

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

243979

BRD4
Bromodomain-containing protein 4

1

20

Small-scale

0.479

High

257742

SIN3B
Paired amphipathic helix protein Sin3b

1

17

High-throughput

0.479

High

265173

SAP30
Histone deacetylase complex subunit SAP30

1

5

High-throughput

0.479

High

295943

MTA2
Metastasis-associated protein MTA2

1

20

High-throughput

0.479

High

308428

KI20A
Kinesin-like protein KIF20A

1

18

High-throughput

0.479

High

328499

MBD3
Methyl-CpG-binding domain protein 3

1

20

High-throughput

0.479

High

346003

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

373731

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

11

High-throughput

0.479

High

384322

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

386152

P53
Cellular tumor antigen p53

1

8

High-throughput

0.479

High

414444

PRGR
Progesterone receptor

1

20

Small-scale

0.479

High

433598

LYN
Tyrosine-protein kinase Lyn

1

6

High-throughput

0.479

High

486872

MYBB
Myb-related protein B

1

15

High-throughput

0.479

High

550618

RS2
Small ribosomal subunit protein uS5

1

5

High-throughput

0.479

High

552009

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

603365

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

5

High-throughput

0.479

High

631352

BRD2
Bromodomain-containing protein 2

1

20

High-throughput

0.479

High

650435

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

11

High-throughput

0.479

High

652752

APEX1
DNA repair nuclease/redox regulator APEX1

1

2

High-throughput

0.479

High

658633

GRK5
G protein-coupled receptor kinase 5

1

1

High-throughput

0.479

High

658634

PHB1
Prohibitin 1

1

9

High-throughput

0.479

High

658635

VGFR2
Vascular endothelial growth factor receptor 2

1

7

High-throughput

0.479

High

658636

COIL
Coilin

1

7

High-throughput

0.479

High

658639

GATA4
Transcription factor GATA-4

1

20

High-throughput

0.479

High

658642

LHX2
LIM/homeobox protein Lhx2

1

11

High-throughput

0.479

High

658665

CAF1A
Chromatin assembly factor 1 subunit A

1

16

High-throughput

0.479

High

658666

CAF1B
Chromatin assembly factor 1 subunit B

1

14

High-throughput

0.479

High

658668

TIF1B
Transcription intermediary factor 1-beta

1

14

High-throughput

0.479

High

658669

G3BP1
Ras GTPase-activating protein-binding protein 1

1

7

High-throughput

0.479

High

658670

MTA1
Metastasis-associated protein MTA1

1

20

High-throughput

0.479

High

658671

KLF9
Krueppel-like factor 9

1

16

High-throughput

0.479

High

658675

SUZ12
Polycomb protein SUZ12

1

9

High-throughput

0.479

High

658676

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.479

High

658677

BRD3
Bromodomain-containing protein 3

1

20

High-throughput

0.479

High

658683

IF16
Gamma-interferon-inducible protein 16

1

10

High-throughput

0.479

High

658687

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

658688

LIN52
Protein lin-52 homolog

1

1

High-throughput

0.479

High

658690

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

9

High-throughput

0.479

High

658691

LIN9
Protein lin-9 homolog

1

4

High-throughput

0.479

High

658695

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

12

High-throughput

0.479

High

658698

SLN11
Schlafen family member 11

1

4

High-throughput

0.479

High

658700

P66A
Transcriptional repressor p66-alpha

1

13

High-throughput

0.479

High

658705

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

8

High-throughput

0.479

High

658706

CGAS
Cyclic GMP-AMP synthase

1

4

High-throughput

0.479

High

658708

HJURP
Holliday junction recognition protein

1

1

High-throughput

0.479

High

658710

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

Small-scale

0.479

High

658711

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

658712

GATD1
GATA zinc finger domain-containing protein 1

1

1

High-throughput

0.479

High

658713

P66B
Transcriptional repressor p66-beta

1

13

High-throughput

0.479

High

658714

FBXW7
F-box/WD repeat-containing protein 7

1

11

High-throughput

0.479

High

658715

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

15

High-throughput

0.479

High

658716

LIN37
Protein lin-37 homolog

1

4

High-throughput

0.479

High

658717

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

658718

Z512B
Zinc finger protein 512B

1

15

High-throughput

0.479

High

658719

PWP2A
PWWP domain-containing protein 2A

1

10

High-throughput

0.479

High

658721

SIN3A
Paired amphipathic helix protein Sin3a

1

17

High-throughput

0.479

High

658723

TBX5
T-box transcription factor TBX5

1

14

High-throughput

0.479

High

658725

MTA3
Metastasis-associated protein MTA3

1

20

High-throughput

0.479

High

658729

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

4

High-throughput

0.479

High

658730

SP130
Histone deacetylase complex subunit SAP130

1

9

High-throughput

0.479

High

658731

BC11A
B-cell lymphoma/leukemia 11A

1

11

High-throughput

0.479

High

658736

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

9

High-throughput

0.479

High

658737

NANOG
Homeobox protein NANOG

1

20

High-throughput

0.479

High

658739

ANLN
Anillin

1

3

High-throughput

0.479

High

658743

RAD18
E3 ubiquitin-protein ligase RAD18

1

4

High-throughput

0.479

High

658744

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

5

High-throughput

0.479

High

658746

MBD2
Methyl-CpG-binding domain protein 2

1

20

High-throughput

0.479

High

658747

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

658753

ZN330
Zinc finger protein 330

1

5

High-throughput

0.479

High

658754

MTF2
Metal-response element-binding transcription factor 2

1

9

High-throughput

0.479

High

658640

EFTU
Elongation factor Tu, mitochondrial

1

4

High-throughput

0.470

High

658733

TXNIP
Thioredoxin-interacting protein

1

3

High-throughput

0.470

High

298188

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

658656

FMR1
Fragile X messenger ribonucleoprotein 1

1

14

High-throughput

0.457

High

135213

E2F3
Transcription factor E2F3

1

5

Small-scale

0.445

High

401472

JUN
Transcription factor Jun

1

17

High-throughput

0.445

High

658738

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.445

High

658750

BAZ2B
Bromodomain adjacent to zinc finger domain protein 2B

1

20

Small-scale

0.445

High

658685

CL16A
Protein CLEC16A

1

2

High-throughput

0.437

High

658689

TM128
Transmembrane protein 128

1

1

High-throughput

0.437

High

658699

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

12

Small-scale

0.437

High

658703

RHG24
Rho GTPase-activating protein 24

1

6

High-throughput

0.437

High

658735

PKHA4
Pleckstrin homology domain-containing family A member 4

1

13

High-throughput

0.437

High

56596

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

3

High-throughput

0.407

High

81598

B7Z3K1
cDNA FLJ51973

1

1

High-throughput

0.407

High

364833

FRIL
Ferritin light chain

1

0

High-throughput

0.279

Low

658693

I23O2
Indoleamine 2,3-dioxygenase 2

1

0

High-throughput

0.279

Low

658720

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024