Protein: FLII
Protein flightless-1 homolog

Gene: FLII
Organism: Homo sapiens
Interactions: 210
UniProt ID: Q13045

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

657487

TMOD1
Tropomodulin-1

4

12

High-throughput

0.895

High

891735

ACTB
Actin, cytoplasmic 1

3

20

High-throughput

0.847

High

1023245

TMOD3
Tropomodulin-3

2

12

High-throughput

0.811

High

1023247

TMOD4
Tropomodulin-4

2

12

High-throughput

0.811

High

929839

ACTG
Actin, cytoplasmic 2

2

19

High-throughput

0.789

High

331503

ACL6A
Actin-like protein 6A

2

18

Small-scale

0.754

High

1023171

LRRF1
Leucine-rich repeat flightless-interacting protein 1

7

2

Small-scale

0.751

High

932132

ACTC
Actin, alpha cardiac muscle 1

1

17

High-throughput

0.665

High

1023242

ANLN
Anillin

3

4

High-throughput

0.656

High

529055

CFTR
Cystic fibrosis transmembrane conductance regulator

3

5

High-throughput

0.643

High

369509

ESR1
Estrogen receptor

2

20

Small-scale

0.629

High

411699

LCK
Tyrosine-protein kinase Lck

1

7

High-throughput

0.618

High

896733

ARP3
Actin-related protein 3

1

19

High-throughput

0.618

High

737779

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

2

15

High-throughput

0.611

High

1023264

LRRF2
Leucine-rich repeat flightless-interacting protein 2

3

11

Small-scale

0.607

High

173577

NPHP1
Nephrocystin-1

1

0

High-throughput

0.586

High

227318

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

244367

BRD4
Bromodomain-containing protein 4

2

2

High-throughput

0.584

High

322550

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

1

High-throughput

0.584

High

346664

MYC
Myc proto-oncogene protein

2

6

High-throughput

0.584

High

749437

BRCA1
Breast cancer type 1 susceptibility protein

2

2

High-throughput

0.584

High

779329

CCNF
Cyclin-F

2

3

High-throughput

0.584

High

1023158

DX39B
Spliceosome RNA helicase DDX39B

2

3

Small-scale

0.584

High

882272

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

High-throughput

0.575

High

924532

GRB2
Growth factor receptor-bound protein 2

1

11

High-throughput

0.575

High

1023176

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

19

High-throughput

0.575

High

261112

SH3L1
Adapter SH3BGRL

2

2

High-throughput

0.571

High

503997

HSP7C
Heat shock cognate 71 kDa protein

2

4

High-throughput

0.571

High

1023195

CARM1
Histone-arginine methyltransferase CARM1

1

2

Small-scale

0.561

High

384750

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.553

High

1023184

LRC31
Leucine-rich repeat-containing protein 31

1

19

High-throughput

0.553

High

1023257

ALK
ALK tyrosine kinase receptor

1

19

Small-scale

0.553

High

739097

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

2

High-throughput

0.541

High

117682

MYO1C
Unconventional myosin-Ic

1

9

High-throughput

0.536

High

215223

STRN
Striatin

1

4

High-throughput

0.536

High

431793

HS90A
Heat shock protein HSP 90-alpha

1

3

Small-scale

0.536

High

580643

ML12A
Myosin regulatory light chain 12A

1

3

High-throughput

0.536

High

598091

FLNA
Filamin-A

1

8

High-throughput

0.536

High

614021

TBG1
Tubulin gamma-1 chain

1

2

High-throughput

0.536

High

625401

CDK2
Cyclin-dependent kinase 2

1

2

High-throughput

0.536

High

724803

MYH9
Myosin-9

1

5

High-throughput

0.536

High

809289

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

3

High-throughput

0.536

High

821757

NEST
Nestin

1

8

High-throughput

0.536

High

850785

PRKX
cAMP-dependent protein kinase catalytic subunit PRKX

1

3

High-throughput

0.536

High

858616

PPP5
Serine/threonine-protein phosphatase 5

1

20

High-throughput

0.536

High

862032

DAPK1
Death-associated protein kinase 1

1

11

High-throughput

0.536

High

902893

DCAF7
DDB1- and CUL4-associated factor 7

1

3

High-throughput

0.536

High

906437

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

15

High-throughput

0.536

High

984572

CALD1
Caldesmon

1

18

High-throughput

0.536

High

1023150

MK07
Mitogen-activated protein kinase 7

1

5

High-throughput

0.536

High

1023151

SRSF5
Serine/arginine-rich splicing factor 5

1

1

High-throughput

0.536

High

1023165

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

7

High-throughput

0.536

High

1023166

DREB
Drebrin

1

4

High-throughput

0.536

High

1023169

KIF7
Kinesin-like protein KIF7

1

3

High-throughput

0.536

High

1023174

PDZ11
PDZ domain-containing protein 11

1

3

High-throughput

0.536

High

1023175

HERC4
Probable E3 ubiquitin-protein ligase HERC4

1

5

High-throughput

0.536

High

1023192

CTU1
Cytoplasmic tRNA 2-thiolation protein 1

1

1

High-throughput

0.536

High

1023198

ABRA
Actin-binding Rho-activating protein

1

2

High-throughput

0.536

High

1023204

FBX30
F-box only protein 30

1

3

High-throughput

0.536

High

1023222

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

6

High-throughput

0.536

High

1023241

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.536

High

1023243

MYO5C
Unconventional myosin-Vc

1

5

High-throughput

0.536

High

1023244

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.536

High

1023252

FBX40
F-box only protein 40

1

3

High-throughput

0.536

High

1023260

SGT1
Protein SGT1 homolog

1

11

High-throughput

0.536

High

1023230

TRAIP
E3 ubiquitin-protein ligase TRAIP

1

8

Small-scale

0.527

High

1023219

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.518

High

793931

MATR3
Matrin-3

1

1

High-throughput

0.515

High

364878

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

426915

CRGD
Gamma-crystallin D

1

0

High-throughput

0.513

High

771452

PSB10
Proteasome subunit beta type-10

1

0

High-throughput

0.513

High

1023163

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1023170

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

1

0

High-throughput

0.513

High

1023183

CC174
Coiled-coil domain-containing protein 174

1

0

High-throughput

0.513

High

1023188

CENPQ
Centromere protein Q

1

0

High-throughput

0.513

High

1023190

MYCPP
C-myc promoter-binding protein

1

0

High-throughput

0.513

High

1023191

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.513

High

1023194

JAZF1
Juxtaposed with another zinc finger protein 1

1

0

High-throughput

0.513

High

1023240

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.513

High

1023253

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.513

High

1023164

NCOA2
Nuclear receptor coactivator 2

1

1

Small-scale

0.501

High

1023261

GRIP1
Glutamate receptor-interacting protein 1

1

8

Small-scale

0.501

High

215621

AKAP8
A-kinase anchor protein 8

1

0

High-throughput

0.493

High

1023187

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

1

3

High-throughput

0.489

High

1023199

KLH34
Kelch-like protein 34

1

2

High-throughput

0.489

High

1023201

TTC9C
Tetratricopeptide repeat protein 9C

1

1

High-throughput

0.489

High

1023248

CFA97
Cilia- and flagella-associated protein 97

1

1

High-throughput

0.489

High

118290

HAX1
HCLS1-associated protein X-1

1

1

High-throughput

0.479

High

129001

PLK4
Serine/threonine-protein kinase PLK4

1

4

Small-scale

0.479

High

214243

SPOP
Speckle-type POZ protein

1

3

Small-scale

0.479

High

233414

NUPR1
Nuclear protein 1

1

3

High-throughput

0.479

High

294777

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

301795

TRI37
E3 ubiquitin-protein ligase TRIM37

1

10

High-throughput

0.479

High

308665

KI20A
Kinesin-like protein KIF20A

1

13

High-throughput

0.479

High

319817

HERC2
E3 ubiquitin-protein ligase HERC2

1

8

High-throughput

0.479

High

350129

RASK
GTPase KRas

1

13

High-throughput

0.479

High

374150

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

High-throughput

0.479

High

397946

ISG15
Ubiquitin-like protein ISG15

1

4

High-throughput

0.479

High

430159

PROF1
Profilin-1

1

2

High-throughput

0.479

High

487386

ANDR
Androgen receptor

1

16

High-throughput

0.479

High

502037

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.479

High

552609

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

569666

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

590881

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

615710

GCSP
Glycine dehydrogenase

1

1

High-throughput

0.479

High

622443

CCND1
G1/S-specific cyclin-D1

1

4

High-throughput

0.479

High

651082

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

673067

CCND2
G1/S-specific cyclin-D2

1

4

Small-scale

0.479

High

681818

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

Small-scale

0.479

High

717044

CTNB1
Catenin beta-1

1

4

High-throughput

0.479

High

720346

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

813006

CAZA2
F-actin-capping protein subunit alpha-2

1

3

High-throughput

0.479

High

813424

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.479

High

817995

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.479

High

841695

CDK9
Cyclin-dependent kinase 9

1

7

High-throughput

0.479

High

850022

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

5

High-throughput

0.479

High

903183

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.479

High

966529

OTUD4
OTU domain-containing protein 4

1

2

Small-scale

0.479

High

998631

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.479

High

1023152

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.479

High

1023154

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

2

High-throughput

0.479

High

1023157

CUL3
Cullin-3

1

3

High-throughput

0.479

High

1023159

TRI14
Tripartite motif-containing protein 14

1

5

High-throughput

0.479

High

1023160

TNIP1
TNFAIP3-interacting protein 1

1

12

High-throughput

0.479

High

1023162

KIF14
Kinesin-like protein KIF14

1

9

High-throughput

0.479

High

1023167

HIF1A
Hypoxia-inducible factor 1-alpha

1

2

High-throughput

0.479

High

1023168

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1023172

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

5

High-throughput

0.479

High

1023173

BRDT
Bromodomain testis-specific protein

1

5

High-throughput

0.479

High

1023178

OTUD3
OTU domain-containing protein 3

1

2

Small-scale

0.479

High

1023180

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.479

High

1023185

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

14

High-throughput

0.479

High

1023186

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.479

High

1023189

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1023200

SYNPO
Synaptopodin

1

3

High-throughput

0.479

High

1023205

FBX25
F-box only protein 25

1

1

High-throughput

0.479

High

1023206

OTU7A
OTU domain-containing protein 7A

1

6

Small-scale

0.479

High

1023207

DCA11
DDB1- and CUL4-associated factor 11

1

2

High-throughput

0.479

High

1023208

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1023209

MY18A
Unconventional myosin-XVIIIa

1

12

High-throughput

0.479

High

1023211

ESR2
Estrogen receptor beta

1

18

High-throughput

0.479

High

1023213

FBXW7
F-box/WD repeat-containing protein 7

1

5

High-throughput

0.479

High

1023217

AURKB
Aurora kinase B

1

6

High-throughput

0.479

High

1023218

MYO19
Unconventional myosin-XIX

1

10

High-throughput

0.479

High

1023220

CIC
Protein capicua homolog

1

2

High-throughput

0.479

High

1023221

CEP89
Centrosomal protein of 89 kDa

1

14

High-throughput

0.479

High

1023224

MYD88
Myeloid differentiation primary response protein MyD88

1

1

Small-scale

0.479

High

1023225

ANM1
Protein arginine N-methyltransferase 1

1

2

Small-scale

0.479

High

1023227

LZTS2
Leucine zipper putative tumor suppressor 2

1

11

High-throughput

0.479

High

1023228

OVOL2
Transcription factor Ovo-like 2

1

6

Small-scale

0.479

High

1023231

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

2

Small-scale

0.479

High

1023232

RNF38
E3 ubiquitin-protein ligase RNF38

1

1

Small-scale

0.479

High

1023233

CCDC8
Coiled-coil domain-containing protein 8

1

2

High-throughput

0.479

High

1023234

CHM4B
Charged multivesicular body protein 4b

1

5

High-throughput

0.479

High

1023235

Q9H4D1
Protein kinase

1

11

High-throughput

0.479

High

1023236

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.479

High

1023237

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

1023239

ECT2
Protein ECT2

1

12

High-throughput

0.479

High

1023246

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

1023250

HDAC6
Histone deacetylase 6

1

5

High-throughput

0.479

High

1023251

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1023254

ANC2
Anaphase-promoting complex subunit 2

1

4

High-throughput

0.479

High

1023255

FBW1B
F-box/WD repeat-containing protein 11

1

5

High-throughput

0.479

High

1023262

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.479

High

1023263

LOXL2
Lysyl oxidase homolog 2

1

3

High-throughput

0.479

High

262441

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

314869

FMNL1
Formin-like protein 1

1

0

Small-scale

0.458

High

450862

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.458

High

583471

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

757590

IF4A3
Eukaryotic initiation factor 4A-III

1

0

High-throughput

0.458

High

822005

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.458

High

880911

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

961083

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

986894

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.458

High

1023155

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.458

High

1023156

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1023161

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1023193

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

1023196

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

1023197

ASXL1
Polycomb group protein ASXL1

1

0

High-throughput

0.458

High

1023203

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1023210

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1023212

TF3B
Transcription factor IIIB 90 kDa subunit

1

0

Small-scale

0.458

High

1023215

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1023226

PAIP2
Polyadenylate-binding protein-interacting protein 2

1

0

High-throughput

0.458

High

1023238

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.458

High

1023249

SYLC
Leucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

1023259

CRYL1
Lambda-crystallin homolog

1

0

High-throughput

0.458

High

56614

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.445

High

401923

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

496943

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

883498

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

11

High-throughput

0.445

High

905863

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

15

High-throughput

0.445

High

1023153

CTBP1
C-terminal-binding protein 1

1

3

High-throughput

0.445

High

1023182

PKHA7
Pleckstrin homology domain-containing family A member 7

1

11

High-throughput

0.445

High

1023223

ZBT18
Zinc finger and BTB domain-containing protein 18

1

9

High-throughput

0.445

High

352599

TNFA
Tumor necrosis factor

1

1

High-throughput

0.437

High

1023179

NXNL2
Nucleoredoxin-like protein 2

1

2

Small-scale

0.437

High

1023181

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.437

High

1023202

OTU6B
Deubiquitinase OTUD6B

1

2

Small-scale

0.437

High

1023216

NXNL1
Nucleoredoxin-like protein 1

1

2

Small-scale

0.437

High

1023256

HECD1
E3 ubiquitin-protein ligase HECTD1

1

2

High-throughput

0.437

High

321064

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.426

High

1023177

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.426

High

239970

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.407

High

1023258

ITM2B
Integral membrane protein 2B

1

2

High-throughput

0.407

High

224932

ZNRD2
Protein ZNRD2

2

0

High-throughput

0.328

High

1023229

NAT9
Alpha/beta-tubulin-N-acetyltransferase 9

2

0

High-throughput

0.328

High

390856

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

1023214

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024