Protein: NCOA4
Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ret-activating protein ELE1)

Gene: NCOA4
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q13772

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0006622 - protein targeting to lysosome
GO:0006879 - intracellular iron ion homeostasis
GO:0008584 - male gonad development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

487414

ANDR
Androgen receptor

13

3

Small-scale

0.763

High

319830

HERC2
E3 ubiquitin-protein ligase HERC2

6

2

Small-scale

0.737

High

365192

FRIH
Ferritin heavy chain

6

2

Small-scale

0.736

High

364886

FRIL
Ferritin light chain

3

2

Small-scale

0.667

High

740521

PPARG
Peroxisome proliferator-activated receptor gamma

2

4

Small-scale

0.594

High

1045320

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

0

High-throughput

0.580

High

1045314

TRIM7
E3 ubiquitin-protein ligase TRIM7

1

1

Small-scale

0.561

High

1045303

TAXB1
Tax1-binding protein 1

2

1

Small-scale

0.533

High

509949

VDR
Vitamin D3 receptor

1

3

Small-scale

0.527

High

587167

RXRA
Retinoic acid receptor RXR-alpha

1

1

Small-scale

0.527

High

130880

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.513

High

906825

PRS4
26S proteasome regulatory subunit 4

1

0

High-throughput

0.513

High

1045299

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.513

High

1045304

RNF10
E3 ubiquitin-protein ligase RNF10

1

0

High-throughput

0.513

High

1045310

GMCL1
Germ cell-less protein-like 1

1

0

High-throughput

0.513

High

369567

ESR1
Estrogen receptor

1

4

Small-scale

0.501

High

1045312

ATX2
Ataxin-2

1

1

High-throughput

0.494

High

681837

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

High-throughput

0.486

High

377314

GCR
Glucocorticoid receptor

1

3

Small-scale

0.481

High

959927

TF2B
Transcription initiation factor IIB

1

0

Small-scale

0.480

High

1045308

KAT2B
Histone acetyltransferase KAT2B

1

0

Small-scale

0.480

High

207047

XRCC3
DNA repair protein XRCC3

1

1

High-throughput

0.479

High

729655

VGFR2
Vascular endothelial growth factor receptor 2

1

1

High-throughput

0.479

High

1025373

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

1

High-throughput

0.479

High

1036560

SQSTM
Sequestosome-1

1

2

High-throughput

0.479

High

1045302

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.479

High

1045315

TRIM5
Tripartite motif-containing protein 5

1

1

Small-scale

0.479

High

1045306

JPH3
Junctophilin-3

1

1

High-throughput

0.470

High

1045319

ATX10
Ataxin-10

1

1

High-throughput

0.470

High

162723

XPO1
Exportin-1

1

0

High-throughput

0.458

High

374204

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

590907

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

1041531

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1045309

OPTN
Optineurin

1

0

High-throughput

0.458

High

1045317

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

786732

GRIA2
Glutamate receptor 2

1

1

High-throughput

0.437

High

1045301

KI21A
Kinesin-like protein KIF21A

1

1

High-throughput

0.437

High

1045307

TFG
Protein TFG

1

1

High-throughput

0.437

High

1045313

KIFC3
Kinesin-like protein KIFC3

1

1

High-throughput

0.437

High

1045300

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

0

High-throughput

0.279

Low

1045305

PRLD2
PRELI domain-containing protein 2

1

0

High-throughput

0.279

Low

1045311

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.279

Low

1045298

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.249

Low

1045316

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

High-throughput

0.249

Low

56620

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low

1045318

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024