Protein: MINK1
Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)

Gene: MINK1
Organism: Homo sapiens
Interactions: 171
UniProt ID: Q8N4C8

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001952 - regulation of cell-matrix adhesion
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

324842

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

4

17

High-throughput

0.900

High

350342

RASK
GTPase KRas

3

20

High-throughput

0.827

High

1233560

TNIK
TRAF2 and NCK-interacting protein kinase

2

17

High-throughput

0.811

High

486037

RAP2A
Ras-related protein Rap-2a

2

15

Small-scale

0.783

High

325808

LATS1
Serine/threonine-protein kinase LATS1

2

20

Small-scale

0.778

High

348783

RASN
GTPase NRas

2

20

High-throughput

0.754

High

349478

RASH
GTPase HRas

2

20

High-throughput

0.754

High

915830

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

209112

NCK2
Cytoplasmic protein NCK2

4

20

High-throughput

0.694

High

814606

V1BR
Vasopressin V1b receptor

1

1

High-throughput

0.691

High

1036732

SQSTM
Sequestosome-1

1

6

High-throughput

0.691

High

1160624

CNKR3
Connector enhancer of kinase suppressor of ras 3

1

8

High-throughput

0.691

High

1233556

STK26
Serine/threonine-protein kinase 26

1

20

High-throughput

0.691

High

1137694

STRP1
Striatin-interacting protein 1

3

14

High-throughput

0.681

High

1233550

STRN4
Striatin-4

3

20

High-throughput

0.681

High

215251

STRN
Striatin

3

20

High-throughput

0.667

High

1022840

STRN3
Striatin-3

3

20

High-throughput

0.667

High

1233526

CNOT9
CCR4-NOT transcription complex subunit 9

3

1

High-throughput

0.667

High

1233571

PHOCN
MOB-like protein phocein

3

20

High-throughput

0.667

High

1233577

TX264
Testis-expressed protein 264

3

1

High-throughput

0.667

High

1233573

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.656

High

61415

CNOT1
CCR4-NOT transcription complex subunit 1

2

1

High-throughput

0.628

High

257380

CNOT3
CCR4-NOT transcription complex subunit 3

2

20

High-throughput

0.628

High

888496

NANO2
Nanos homolog 2

2

1

High-throughput

0.628

High

1233539

TB182
182 kDa tankyrase-1-binding protein

2

4

High-throughput

0.628

High

1233554

CNOT2
CCR4-NOT transcription complex subunit 2

2

2

High-throughput

0.628

High

1233561

CNO11
CCR4-NOT transcription complex subunit 11

2

1

High-throughput

0.628

High

557740

NCK1
SH2/SH3 adapter protein NCK1

2

20

Small-scale

0.626

High

120535

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

411790

LCK
Tyrosine-protein kinase Lck

1

13

High-throughput

0.618

High

432054

HS90A
Heat shock protein HSP 90-alpha

1

13

High-throughput

0.618

High

433891

LYN
Tyrosine-protein kinase Lyn

1

13

High-throughput

0.618

High

438348

HS90B
Heat shock protein HSP 90-beta

1

13

High-throughput

0.618

High

508100

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.618

High

545493

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

564611

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

586853

CSK22
Casein kinase II subunit alpha'

1

10

High-throughput

0.618

High

592368

RAB5A
Ras-related protein Rab-5A

1

6

High-throughput

0.618

High

872460

EPHA5
Ephrin type-A receptor 5

1

20

High-throughput

0.618

High

876440

AFAD
Afadin

1

19

High-throughput

0.618

High

892483

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

925434

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

931732

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.618

High

934307

CSK21
Casein kinase II subunit alpha

1

13

High-throughput

0.618

High

1070297

RAB35
Ras-related protein Rab-35

1

10

High-throughput

0.618

High

1072547

EPHA7
Ephrin type-A receptor 7

1

17

High-throughput

0.618

High

1076659

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

1081533

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.618

High

1083868

NTRK2
BDNF/NT-3 growth factors receptor

1

20

High-throughput

0.618

High

1233520

MINK1
Misshapen-like kinase 1

1

16

High-throughput

0.618

High

1233525

DNJC9
DnaJ homolog subfamily C member 9

1

3

High-throughput

0.618

High

1233538

OSBL8
Oxysterol-binding protein-related protein 8

1

1

High-throughput

0.618

High

1233541

DNJC5
DnaJ homolog subfamily C member 5

1

5

High-throughput

0.618

High

1233542

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1233543

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

1233546

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

266570

GPC4
Glypican-4

2

1

High-throughput

0.611

High

876010

ECHB
Trifunctional enzyme subunit beta, mitochondrial

2

2

High-throughput

0.611

High

1233557

CT2NL
CTTNBP2 N-terminal-like protein

2

20

High-throughput

0.611

High

275450

PR15A
Protein phosphatase 1 regulatory subunit 15A

2

0

High-throughput

0.602

High

1233559

CNOT7
CCR4-NOT transcription complex subunit 7

2

0

High-throughput

0.602

High

928384

DYL1
Dynein light chain 1, cytoplasmic

2

8

High-throughput

0.601

High

912993

ARF6
ADP-ribosylation factor 6

2

7

High-throughput

0.584

High

240096

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.575

High

369994

ESR1
Estrogen receptor

2

11

High-throughput

0.571

High

1139357

IER5
Immediate early response gene 5 protein

2

0

Small-scale

0.569

High

778212

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

2

1

High-throughput

0.558

High

1233522

ZCH10
Zinc finger CCHC domain-containing protein 10

2

1

High-throughput

0.558

High

904851

1433G
14-3-3 protein gamma

1

20

High-throughput

0.554

High

982271

1433F
14-3-3 protein eta

1

20

High-throughput

0.554

High

81970

HNRC3
Heterogeneous nuclear ribonucleoprotein C-like 3

1

4

High-throughput

0.553

High

793390

MUC18
Cell surface glycoprotein MUC18

1

9

High-throughput

0.553

High

963239

U2AF1
Splicing factor U2AF 35 kDa subunit

1

1

High-throughput

0.553

High

1069947

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

4

High-throughput

0.553

High

118887

GTPB1
GTP-binding protein 1

1

6

High-throughput

0.536

High

304244

UBR5
E3 ubiquitin-protein ligase UBR5

1

20

High-throughput

0.536

High

387094

P53
Cellular tumor antigen p53

1

2

High-throughput

0.536

High

737403

LONM
Lon protease homolog, mitochondrial

1

4

High-throughput

0.536

High

813606

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.536

High

826468

FNTB
Protein farnesyltransferase subunit beta

1

1

High-throughput

0.536

High

867230

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

1

High-throughput

0.536

High

878137

PKNX1
Homeobox protein PKNOX1

1

1

High-throughput

0.536

High

974921

CAV1
Caveolin-1

1

6

High-throughput

0.536

High

1031565

ATM
Serine-protein kinase ATM

1

1

High-throughput

0.536

High

1047049

RPGF1
Rap guanine nucleotide exchange factor 1

1

2

High-throughput

0.536

High

1069422

TEBP
Prostaglandin E synthase 3

1

2

High-throughput

0.536

High

1102049

ERC6L
DNA excision repair protein ERCC-6-like

1

4

High-throughput

0.536

High

1102601

INSY1
Inhibitory synaptic factor 1

1

2

High-throughput

0.536

High

1157571

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.536

High

1169274

BAKOR
Beclin 1-associated autophagy-related key regulator

1

1

High-throughput

0.536

High

1216114

GLT13
Polypeptide N-acetylgalactosaminyltransferase 13

1

1

High-throughput

0.536

High

1233528

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

9

High-throughput

0.536

High

1233531

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

4

High-throughput

0.536

High

1233540

CPVL
Probable serine carboxypeptidase CPVL

1

4

High-throughput

0.536

High

1233544

SH24A
SH2 domain-containing protein 4A

1

17

High-throughput

0.536

High

1233548

WDR6
tRNA

1

10

High-throughput

0.536

High

1233566

NUDC
Nuclear migration protein nudC

1

1

High-throughput

0.536

High

1233568

KLH20
Kelch-like protein 20

1

3

High-throughput

0.536

High

1233570

SGT1
Protein SGT1 homolog

1

8

High-throughput

0.536

High

1233576

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

4

High-throughput

0.536

High

961194

HSF1
Heat shock factor protein 1

1

1

Small-scale

0.527

High

684206

1433S
14-3-3 protein sigma

1

20

High-throughput

0.515

High

909810

1433E
14-3-3 protein epsilon

1

12

High-throughput

0.515

High

957890

EFNB1
Ephrin-B1

1

0

High-throughput

0.513

High

1160345

ALKB5
RNA demethylase ALKBH5

1

0

High-throughput

0.513

High

1233536

RIOK2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.513

High

1233545

CNO10
CCR4-NOT transcription complex subunit 10

1

0

High-throughput

0.513

High

1233529

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

11

High-throughput

0.501

High

1233533

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

19

High-throughput

0.501

High

224991

ZNRD2
Protein ZNRD2

1

1

High-throughput

0.489

High

1233532

FACOS
FANCD2 opposite strand protein

1

1

High-throughput

0.489

High

1233562

ABT1
Activator of basal transcription 1

1

3

High-throughput

0.489

High

1233565

T3JAM
TRAF3-interacting JNK-activating modulator

1

20

High-throughput

0.489

High

1233567

SL9A8
Sodium/hydrogen exchanger 8

1

2

High-throughput

0.489

High

1233575

GPC6
Glypican-6 [Cleaved into: Secreted glypican-6]

1

1

High-throughput

0.489

High

120000

AP3B1
AP-3 complex subunit beta-1

1

4

High-throughput

0.479

High

279635

FLOT1
Flotillin-1

1

3

High-throughput

0.479

High

308883

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

322876

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.479

High

522061

CADH1
Cadherin-1

1

6

High-throughput

0.479

High

527619

LAMP2
Lysosome-associated membrane glycoprotein 2

1

6

High-throughput

0.479

High

539053

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

2

High-throughput

0.479

High

547137

EZRI
Ezrin

1

9

High-throughput

0.479

High

567165

CXA1
Gap junction alpha-1 protein

1

6

High-throughput

0.479

High

647104

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

683539

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.479

High

825214

RL34
Large ribosomal subunit protein eL34

1

1

High-throughput

0.479

High

881530

ARL4C
ADP-ribosylation factor-like protein 4C

1

13

High-throughput

0.479

High

900203

RL37A
Large ribosomal subunit protein eL43

1

2

High-throughput

0.479

High

921903

RL30
Large ribosomal subunit protein eL30

1

3

High-throughput

0.479

High

922864

RL32
Large ribosomal subunit protein eL32

1

2

High-throughput

0.479

High

924703

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.479

High

927301

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

942208

GTF2I
General transcription factor II-I

1

1

High-throughput

0.479

High

969851

KIF23
Kinesin-like protein KIF23

1

18

High-throughput

0.479

High

1110023

AR13B
ADP-ribosylation factor-like protein 13B

1

15

High-throughput

0.479

High

1151971

LTOR1
Ragulator complex protein LAMTOR1

1

4

High-throughput

0.479

High

1174260

MOB3C
MOB kinase activator 3C

1

20

High-throughput

0.479

High

1198329

MOB3B
MOB kinase activator 3B

1

20

High-throughput

0.479

High

1233530

CK052
Uncharacterized protein C11orf52

1

4

High-throughput

0.479

High

1233547

E41LA
Band 4.1-like protein 4A

1

7

High-throughput

0.479

High

1233551

FGOP2
FGFR1 oncogene partner 2

1

15

High-throughput

0.479

High

1233552

ARL15
ADP-ribosylation factor-like protein 15

1

9

High-throughput

0.479

High

1233555

RCC2
Protein RCC2

1

5

High-throughput

0.479

High

1233563

MARE3
Microtubule-associated protein RP/EB family member 3

1

2

High-throughput

0.479

High

1233569

AP3M1
AP-3 complex subunit mu-1

1

2

High-throughput

0.479

High

1233572

RL36
Large ribosomal subunit protein eL36

1

2

High-throughput

0.479

High

1233574

DCAF1
DDB1- and CUL4-associated factor 1

1

4

High-throughput

0.479

High

1233549

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.457

High

56675

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.445

High

307832

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

1

1

High-throughput

0.437

High

553179

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.437

High

1084097

OCLN
Occludin

1

5

High-throughput

0.437

High

1188553

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.437

High

1230271

CXD3
Gap junction delta-3 protein

1

6

High-throughput

0.437

High

1233521

ARL14
ADP-ribosylation factor-like protein 14

1

8

High-throughput

0.437

High

1233523

BRX1
Ribosome biogenesis protein BRX1 homolog

1

2

High-throughput

0.437

High

1233527

ESR2
Estrogen receptor beta

1

10

High-throughput

0.437

High

1233534

EBP2
Probable rRNA-processing protein EBP2

1

1

High-throughput

0.437

High

1233535

CG050
Uncharacterized protein C7orf50

1

2

High-throughput

0.437

High

1233558

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.437

High

1233564

SRRM2
Serine/arginine repetitive matrix protein 2

1

6

High-throughput

0.437

High

1233553

GRHL1
Grainyhead-like protein 1 homolog

1

1

High-throughput

0.407

High

1233524

SEN15
tRNA-splicing endonuclease subunit Sen15

2

0

High-throughput

0.328

High

571166

EGLN
Endoglin

1

0

High-throughput

0.279

Low

612030

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.279

Low

617760

NFYA
Nuclear transcription factor Y subunit alpha

1

0

High-throughput

0.279

Low

352184

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

456424

PPBI
Intestinal-type alkaline phosphatase

1

0

High-throughput

0.249

Low

1233537

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024