Protein: NEK1
Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)

Gene: NEK1
Organism: Homo sapiens
Interactions: 83
UniProt ID: Q96PY6

Gene Ontology (top 5):
GO:0000242 - pericentriolar material
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004713 - protein tyrosine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1203503

SKAP1
Src kinase-associated phosphoprotein 1

3

20

High-throughput

0.861

High

1130466

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

17

Small-scale

0.799

High

1105480

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

14

High-throughput

0.778

High

982402

1433F
14-3-3 protein eta

5

20

Small-scale

0.716

High

1039153

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

14

High-throughput

0.691

High

1159371

NEK5
Serine/threonine-protein kinase Nek5

1

17

High-throughput

0.691

High

683640

1433B
14-3-3 protein beta/alpha

4

20

High-throughput

0.691

High

905009

1433G
14-3-3 protein gamma

4

20

High-throughput

0.691

High

215541

CF410
Cilia- and flagella-associated protein 410

3

11

Small-scale

0.674

High

1262186

TEKT4
Tektin-4

3

2

High-throughput

0.667

High

1299972

ZN350
Zinc finger protein 350

1

4

Small-scale

0.656

High

647203

1433T
14-3-3 protein theta

3

20

High-throughput

0.650

High

1116283

VP26B
Vacuolar protein sorting-associated protein 26B

3

0

High-throughput

0.638

High

1233707

KIF2B
Kinesin-like protein KIF2B

2

12

High-throughput

0.628

High

1291369

CPNE2
Copine-2

2

4

High-throughput

0.628

High

1298658

ODAD4
Outer dynein arm-docking complex subunit 4

2

13

High-throughput

0.628

High

1299967

ALS2
Alsin

2

9

High-throughput

0.628

High

617012

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

9

Small-scale

0.619

High

488784

ARAF
Serine/threonine-protein kinase A-Raf

1

20

High-throughput

0.618

High

835499

GSK3A
Glycogen synthase kinase-3 alpha

1

20

High-throughput

0.618

High

835951

GSK3B
Glycogen synthase kinase-3 beta

1

20

High-throughput

0.618

High

1299975

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.618

High

909932

1433E
14-3-3 protein epsilon

2

20

High-throughput

0.611

High

927425

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.611

High

1299970

WDR83
WD repeat domain-containing protein 83

3

13

High-throughput

0.609

High

1237712

ZN615
Zinc finger protein 615

1

3

Small-scale

0.590

High

1299966

NEK1
Serine/threonine-protein kinase Nek1

1

17

Small-scale

0.590

High

941703

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

7

Small-scale

0.579

High

373056

VTNC
Vitronectin

2

3

High-throughput

0.574

High

1299969

FEZ1
Fasciculation and elongation protein zeta-1

1

1

Small-scale

0.552

High

1299979

FEZ2
Fasciculation and elongation protein zeta-2

1

1

Small-scale

0.552

High

1299984

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

20

High-throughput

0.536

High

150000

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

1

9

High-throughput

0.536

High

365028

FRIL
Ferritin light chain

1

6

High-throughput

0.536

High

515926

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

4

High-throughput

0.536

High

639051

S100P
Protein S100-P

1

11

High-throughput

0.536

High

1050034

SCRIB
Protein scribble homolog

1

13

High-throughput

0.536

High

931351

YBOX1
Y-box-binding protein 1

1

8

High-throughput

0.515

High

1299968

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.513

High

1299976

SPAT7
Spermatogenesis-associated protein 7

1

0

High-throughput

0.513

High

1299977

VPS29
Vacuolar protein sorting-associated protein 29

1

0

High-throughput

0.513

High

802484

ATRX
Transcriptional regulator ATRX

1

10

Small-scale

0.508

High

835101

TSC2
Tuberin

1

2

Small-scale

0.508

High

1019089

TP53B
TP53-binding protein 1

1

9

Small-scale

0.508

High

1299974

EXOS4
Exosome complex component RRP41

1

1

High-throughput

0.508

High

1299978

CTNL1
Alpha-catulin

1

5

Small-scale

0.508

High

1299983

KIF3A
Kinesin-like protein KIF3A

1

8

Small-scale

0.508

High

1298712

TMM74
Transmembrane protein 74

1

3

High-throughput

0.489

High

1299981

PNMA2
Paraneoplastic antigen Ma2

1

6

High-throughput

0.489

High

837064

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.486

High

1069264

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

1

4

Small-scale

0.481

High

163163

XPO1
Exportin-1

1

20

High-throughput

0.479

High

166768

CE290
Centrosomal protein of 290 kDa

1

20

High-throughput

0.479

High

232439

KDM1A
Lysine-specific histone demethylase 1A

1

7

High-throughput

0.479

High

325333

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

3

High-throughput

0.479

High

347638

MYC
Myc proto-oncogene protein

1

15

High-throughput

0.479

High

379754

MYCN
N-myc proto-oncogene protein

1

16

High-throughput

0.479

High

430308

PROF1
Profilin-1

1

3

High-throughput

0.479

High

986017

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

12

High-throughput

0.479

High

1038156

ATR
Serine/threonine-protein kinase ATR

1

17

Small-scale

0.479

High

1038639

HDAC1
Histone deacetylase 1

1

14

High-throughput

0.479

High

1104140

EMAL3
Echinoderm microtubule-associated protein-like 3

1

19

High-throughput

0.479

High

1147642

FTM
Protein fantom

1

19

High-throughput

0.479

High

1188737

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

9

High-throughput

0.479

High

1200586

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1267848

CNOT9
CCR4-NOT transcription complex subunit 9

1

1

High-throughput

0.479

High

1285331

PF21A
PHD finger protein 21A

1

10

High-throughput

0.479

High

1291277

DYL2
Dynein light chain 2, cytoplasmic

1

13

High-throughput

0.479

High

1299971

WWTR1
WW domain-containing transcription regulator protein 1

1

20

High-throughput

0.479

High

1299980

RCOR1
REST corepressor 1

1

8

High-throughput

0.479

High

1299982

MARE3
Microtubule-associated protein RP/EB family member 3

1

5

High-throughput

0.479

High

230996

CE104
Centrosomal protein of 104 kDa

1

0

High-throughput

0.458

High

1263401

ATRIP
ATR-interacting protein

1

0

Small-scale

0.458

High

409382

CASB
Beta-casein

1

2

Small-scale

0.457

High

1058707

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

4

Small-scale

0.457

High

56711

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

6

High-throughput

0.445

High

1299973

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

9

High-throughput

0.445

High

101091

APRIO
Alternative prion protein

1

7

High-throughput

0.437

High

1125103

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.279

Low

1149962

REP15
Rab15 effector protein

1

0

High-throughput

0.279

Low

1156186

CK087
Uncharacterized protein C11orf87

1

0

High-throughput

0.279

Low

352224

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024