Protein: H2AW
Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)

Gene: H2AW, MACROH2A2
Organism: Homo sapiens
Interactions: 196
UniProt ID: Q9P0M6

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin
GO:0000786 - nucleosome
GO:0000976 - transcription cis-regulatory region binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

935316

H31
Histone H3.1

4

20

High-throughput

0.873

High

996939

SSRP1
FACT complex subunit SSRP1

3

20

High-throughput

0.871

High

261026

H2AY
Core histone macro-H2A.1

3

16

High-throughput

0.861

High

1282975

H2B1A
Histone H2B type 1-A

3

20

High-throughput

0.861

High

918741

H2B1C
Histone H2B type 1-C/E/F/G/I

3

20

High-throughput

0.827

High

832748

MCM2
DNA replication licensing factor MCM2

2

20

High-throughput

0.811

High

975529

CENPC
Centromere protein C

2

12

High-throughput

0.811

High

1115591

GLYR1
Cytokine-like nuclear factor N-PAC

2

11

High-throughput

0.811

High

1147782

SPT2
Protein SPT2 homolog

2

5

High-throughput

0.811

High

1216276

H2A2B
Histone H2A type 2-B

2

17

High-throughput

0.811

High

1349702

SP16H
FACT complex subunit SPT16

2

12

High-throughput

0.811

High

470185

H2AZ
Histone H2A.Z

2

20

High-throughput

0.789

High

1299139

IPO9
Importin-9

2

10

High-throughput

0.726

High

1136699

H37
Histone H3-7

2

20

High-throughput

0.712

High

420890

H2B1J
Histone H2B type 1-J

1

20

High-throughput

0.691

High

952668

H33
Histone H3.3

1

20

High-throughput

0.691

High

1087446

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.691

High

1190732

HDGR2
Hepatoma-derived growth factor-related protein 2

1

20

High-throughput

0.691

High

1231257

H2B3B
Histone H2B type 3-B

1

20

High-throughput

0.691

High

1218137

APLF
Aprataxin and PNK-like factor

3

6

High-throughput

0.667

High

1349703

U3KQK0
Histone H2B

1

20

High-throughput

0.665

High

1080416

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

Small-scale

0.646

High

1349692

NUFP1
FMR1-interacting protein NUFIP1

3

0

High-throughput

0.638

High

176296

PPM1G
Protein phosphatase 1G

2

13

High-throughput

0.628

High

196215

RRP8
Ribosomal RNA-processing protein 8

2

1

High-throughput

0.628

High

236842

CCNT1
Cyclin-T1

2

3

High-throughput

0.628

High

237416

CCNT2
Cyclin-T2

2

3

High-throughput

0.628

High

275753

ZN189
Zinc finger protein 189

2

2

High-throughput

0.628

High

303514

HEXI1
Protein HEXIM1

2

13

High-throughput

0.628

High

401155

RLA0
Large ribosomal subunit protein uL10

2

7

High-throughput

0.628

High

789567

RBM34
RNA-binding protein 34

2

11

High-throughput

0.628

High

913808

RL7A
Large ribosomal subunit protein eL8

2

5

High-throughput

0.628

High

967092

XPC
DNA repair protein complementing XP-C cells

2

8

High-throughput

0.628

High

977324

CEBPZ
CCAAT/enhancer-binding protein zeta

2

1

High-throughput

0.628

High

1019374

TRI26
Tripartite motif-containing protein 26

2

6

High-throughput

0.628

High

1037901

PRP4K
Serine/threonine-protein kinase PRP4 homolog

2

20

High-throughput

0.628

High

1058056

RRP5
Protein RRP5 homolog

2

5

High-throughput

0.628

High

1058167

BMS1
Ribosome biogenesis protein BMS1 homolog

2

4

High-throughput

0.628

High

1065899

RRS1
Ribosome biogenesis regulatory protein homolog

2

2

High-throughput

0.628

High

1073279

PUM3
Pumilio homolog 3

2

2

High-throughput

0.628

High

1139183

RSBN1
Lysine-specific demethylase 9

2

1

High-throughput

0.628

High

1153225

ZN770
Zinc finger protein 770

2

2

High-throughput

0.628

High

1170046

MMS22
Protein MMS22-like

2

5

High-throughput

0.628

High

1237593

DDX51
ATP-dependent RNA helicase DDX51

2

11

High-throughput

0.628

High

1239562

ZFP62
Zinc finger protein 62 homolog

2

1

High-throughput

0.628

High

1259530

NOC3L
Nucleolar complex protein 3 homolog

2

6

High-throughput

0.628

High

1264313

BBX
HMG box transcription factor BBX

2

4

High-throughput

0.628

High

1293196

TONSL
Tonsoku-like protein

2

17

High-throughput

0.628

High

1300539

PURB
Transcriptional regulator protein Pur-beta

2

5

High-throughput

0.628

High

1309654

MBB1A
Myb-binding protein 1A

2

3

High-throughput

0.628

High

1326274

REXO4
RNA exonuclease 4

2

1

High-throughput

0.628

High

1332926

RPF2
Ribosome production factor 2 homolog

2

2

High-throughput

0.628

High

1335285

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

2

3

High-throughput

0.628

High

1347947

TEX10
Testis-expressed protein 10

2

2

High-throughput

0.628

High

1348084

CARF
CDKN2A-interacting protein

2

2

High-throughput

0.628

High

1349691

PARP2
Poly [ADP-ribose] polymerase 2

2

19

High-throughput

0.628

High

1349701

RBM19
Probable RNA-binding protein 19

2

20

High-throughput

0.628

High

1307097

H2B1N
Histone H2B type 1-N

1

20

High-throughput

0.621

High

241652

H2B1K
Histone H2B type 1-K

1

20

High-throughput

0.618

High

391940

H2A1B
Histone H2A type 1-B/E

1

16

High-throughput

0.618

High

470593

H2A1
Histone H2A type 1

1

16

High-throughput

0.618

High

850992

HDGF
Hepatoma-derived growth factor

1

20

High-throughput

0.618

High

918054

H4
Histone H4

1

15

High-throughput

0.618

High

924198

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

20

High-throughput

0.618

High

1059910

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.618

High

1157235

H3C
Histone H3.3C

1

20

High-throughput

0.618

High

1174673

H32
Histone H3.2

1

20

High-throughput

0.618

High

1237504

CGAS
Cyclic GMP-AMP synthase

1

1

High-throughput

0.618

High

1345441

RAD18
E3 ubiquitin-protein ligase RAD18

1

6

High-throughput

0.618

High

1349695

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

20

High-throughput

0.618

High

1063655

SUZ12
Polycomb protein SUZ12

2

6

Small-scale

0.611

High

1349696

RL26L
Ribosomal protein uL24-like

2

9

High-throughput

0.611

High

1184477

CENPQ
Centromere protein Q

2

0

High-throughput

0.602

High

1187618

TRM1L
TRMT1-like protein

2

0

High-throughput

0.602

High

348103

MYC
Myc proto-oncogene protein

2

10

High-throughput

0.584

High

377754

GCR
Glucocorticoid receptor

2

15

Small-scale

0.584

High

631613

BRD2
Bromodomain-containing protein 2

2

20

High-throughput

0.584

High

1067170

BRD3
Bromodomain-containing protein 3

2

20

High-throughput

0.584

High

230094

NPA1P
Nucleolar pre-ribosomal-associated protein 1

2

1

High-throughput

0.574

High

1150372

RL7L
Ribosomal protein uL30-like

2

2

High-throughput

0.574

High

1255227

BRX1
Ribosome biogenesis protein BRX1 homolog

2

12

High-throughput

0.574

High

1306830

EBP2
Probable rRNA-processing protein EBP2

2

4

High-throughput

0.574

High

1315960

MAK16
Protein MAK16 homolog

2

2

High-throughput

0.574

High

1326354

DDX24
ATP-dependent RNA helicase DDX24

2

9

High-throughput

0.574

High

1334496

RPF1
Ribosome production factor 1

2

6

High-throughput

0.574

High

1342321

ZCC17
Zinc finger CCHC domain-containing protein 17

2

4

High-throughput

0.574

High

1346773

DDX18
ATP-dependent RNA helicase DDX18

2

11

High-throughput

0.574

High

1347035

RBM28
RNA-binding protein 28

2

14

High-throughput

0.574

High

1348209

TBA8
Tubulin alpha-8 chain

2

3

High-throughput

0.574

High

1238300

F133A
Protein FAM133A

2

1

High-throughput

0.553

High

1327927

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

9

High-throughput

0.541

High

126485

FOXE1
Forkhead box protein E1

1

6

High-throughput

0.536

High

130282

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

13

High-throughput

0.536

High

242589

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

4

High-throughput

0.536

High

279047

RAD17
Cell cycle checkpoint protein RAD17

1

12

High-throughput

0.536

High

398960

HMGN2
Non-histone chromosomal protein HMG-17

1

13

High-throughput

0.536

High

400680

RLA2
Large ribosomal subunit protein P2

1

2

High-throughput

0.536

High

418739

NPM
Nucleophosmin

1

8

High-throughput

0.536

High

426747

H10
Histone H1.0

1

7

High-throughput

0.536

High

449827

HMGB1
High mobility group protein B1

1

20

High-throughput

0.536

High

455952

PARP1
Poly [ADP-ribose] polymerase 1

1

20

High-throughput

0.536

High

497703

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.536

High

508751

TOP1
DNA topoisomerase 1

1

8

High-throughput

0.536

High

509147

TOP2A
DNA topoisomerase 2-alpha

1

9

High-throughput

0.536

High

563517

ZNF22
Zinc finger protein 22

1

4

High-throughput

0.536

High

565053

HMGA1
High mobility group protein HMG-I/HMG-Y

1

8

High-throughput

0.536

High

595451

LMNB1
Lamin-B1

1

8

High-throughput

0.536

High

708532

MCM4
DNA replication licensing factor MCM4

1

20

High-throughput

0.536

High

722304

RFC1
Replication factor C subunit 1

1

9

High-throughput

0.536

High

736781

RL4
Large ribosomal subunit protein uL4

1

3

High-throughput

0.536

High

739328

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

4

High-throughput

0.536

High

760366

RL3
Large ribosomal subunit protein uL3

1

6

High-throughput

0.536

High

849596

GPM6A
Neuronal membrane glycoprotein M6-a

1

1

High-throughput

0.536

High

899386

RL15
Large ribosomal subunit protein eL15

1

1

High-throughput

0.536

High

900296

RL37A
Large ribosomal subunit protein eL43

1

2

High-throughput

0.536

High

911278

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.536

High

923571

RL8
Large ribosomal subunit protein uL2

1

2

High-throughput

0.536

High

942996

SRPK2
SRSF protein kinase 2

1

12

High-throughput

0.536

High

948850

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

2

High-throughput

0.536

High

1026839

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

1

4

High-throughput

0.536

High

1047574

KGP1
cGMP-dependent protein kinase 1

1

19

High-throughput

0.536

High

1061275

NUMA1
Nuclear mitotic apparatus protein 1

1

15

High-throughput

0.536

High

1075263

TEAD2
Transcriptional enhancer factor TEF-4

1

1

High-throughput

0.536

High

1116596

LARP7
La-related protein 7

1

20

High-throughput

0.536

High

1153954

IFIX
Pyrin and HIN domain-containing protein 1

1

6

High-throughput

0.536

High

1158931

MED27
Mediator of RNA polymerase II transcription subunit 27

1

4

High-throughput

0.536

High

1183248

COX15
Heme A synthase COX15

1

2

High-throughput

0.536

High

1235069

ZC3H8
Zinc finger CCCH domain-containing protein 8

1

6

High-throughput

0.536

High

1307522

VRK1
Serine/threonine-protein kinase VRK1

1

5

High-throughput

0.536

High

1317913

GTPB4
GTP-binding protein 4

1

2

High-throughput

0.536

High

1328690

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

4

High-throughput

0.536

High

1333552

DDX31
ATP-dependent DNA helicase DDX31

1

8

High-throughput

0.536

High

1343150

SSF1
Suppressor of SWI4 1 homolog

1

2

High-throughput

0.536

High

1344141

DDX21
Nucleolar RNA helicase 2

1

10

High-throughput

0.536

High

1346958

NLE1
Notchless protein homolog 1

1

9

High-throughput

0.536

High

1349697

NIP7
60S ribosome subunit biogenesis protein NIP7 homolog

1

2

High-throughput

0.536

High

1349698

RUVB2
RuvB-like 2

1

12

High-throughput

0.536

High

1349700

NOC2L
Nucleolar complex protein 2 homolog

1

4

High-throughput

0.536

High

365098

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

802249

NOP2
Probable 28S rRNA

1

0

High-throughput

0.513

High

1216332

RIOX2
Ribosomal oxygenase 2

1

0

High-throughput

0.513

High

1270482

HDAC2
Histone deacetylase 2

1

20

Small-scale

0.500

High

315433

NSA2
Ribosome biogenesis protein NSA2 homolog

1

1

High-throughput

0.489

High

1158135

DHX57
Putative ATP-dependent RNA helicase DHX57

1

16

High-throughput

0.489

High

1172903

NKAP1
Uncharacterized protein NKAPD1

1

2

High-throughput

0.489

High

1241226

NECP1
Adaptin ear-binding coat-associated protein 1

1

3

High-throughput

0.489

High

1310611

LLPH
Protein LLP homolog

1

1

High-throughput

0.489

High

1349693

MRT4
mRNA turnover protein 4 homolog

1

7

High-throughput

0.489

High

1349699

KLH20
Kelch-like protein 20

1

3

High-throughput

0.489

High

170498

TIF1A
Transcription intermediary factor 1-alpha

1

18

High-throughput

0.479

High

210339

PRC1
Protein regulator of cytokinesis 1

1

8

High-throughput

0.479

High

233663

NUPR1
Nuclear protein 1

1

4

High-throughput

0.479

High

245038

BRD4
Bromodomain-containing protein 4

1

20

High-throughput

0.479

High

268310

EED
Polycomb protein EED

1

17

High-throughput

0.479

High

309118

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

379969

MYCN
N-myc proto-oncogene protein

1

11

High-throughput

0.479

High

417438

ENOA
Alpha-enolase

1

2

High-throughput

0.479

High

488028

RARA
Retinoic acid receptor alpha

1

12

Small-scale

0.479

High

553930

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.479

High

652467

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

669028

PML
Protein PML

1

7

High-throughput

0.479

High

721649

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

742573

SYUA
Alpha-synuclein

1

2

High-throughput

0.479

High

780235

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

898776

RL26
Large ribosomal subunit protein uL24

1

9

High-throughput

0.479

High

970036

KIF23
Kinesin-like protein KIF23

1

16

High-throughput

0.479

High

1054637

RBM39
RNA-binding protein 39

1

13

High-throughput

0.479

High

1057413

SMC1A
Structural maintenance of chromosomes protein 1A

1

6

High-throughput

0.479

High

1066799

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.479

High

1086004

IF16
Gamma-interferon-inducible protein 16

1

6

High-throughput

0.479

High

1122705

ESCO2
N-acetyltransferase ESCO2

1

3

Small-scale

0.479

High

1235678

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

3

High-throughput

0.479

High

1251056

SNIP1
Smad nuclear-interacting protein 1

1

3

High-throughput

0.479

High

1330529

CHM4B
Charged multivesicular body protein 4b

1

9

High-throughput

0.479

High

1333774

ECT2
Protein ECT2

1

4

High-throughput

0.479

High

1334034

WDR76
WD repeat-containing protein 76

1

20

High-throughput

0.479

High

1349689

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

15

High-throughput

0.479

High

1349690

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

799023

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

1083023

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.458

High

989159

FMR1
Fragile X messenger ribonucleoprotein 1

1

3

High-throughput

0.457

High

402563

JUN
Transcription factor Jun

1

13

High-throughput

0.445

High

149376

CTRO
Citron Rho-interacting kinase

1

13

High-throughput

0.437

High

256115

OBSL1
Obscurin-like protein 1

1

7

High-throughput

0.437

High

1018366

MERTK
Tyrosine-protein kinase Mer

1

6

High-throughput

0.437

High

1061654

CUL7
Cullin-7

1

3

High-throughput

0.437

High

1201730

ZCH18
Zinc finger CCCH domain-containing protein 18

1

14

High-throughput

0.437

High

1286729

CHM4C
Charged multivesicular body protein 4c

1

9

High-throughput

0.437

High

1331497

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

1349694

HECD1
E3 ubiquitin-protein ligase HECTD1

1

12

High-throughput

0.437

High

56759

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

3

High-throughput

0.407

High

1346819

KTU
Protein kintoun

3

0

High-throughput

0.347

High

1049401

URB2
Unhealthy ribosome biogenesis protein 2 homolog

2

0

High-throughput

0.328

High

1242468

PAPD5
Terminal nucleotidyltransferase 4B

1

0

High-throughput

0.279

Low

1308916

RM34
Large ribosomal subunit protein bL34m

1

0

High-throughput

0.279

Low

1203179

MTMRD
Myotubularin-related protein 13

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024