Protein: SC6A1
Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1)

Gene: SC6A1, Slc6a1
Organism: Mus musculus
Interactions: 67
UniProt ID: P31648

Gene Ontology (top 5):
GO:0005283 - amino acid:sodium symporter activity
GO:0005332 - gamma-aminobutyric acid:sodium:chloride symporter activity
GO:0005886 - plasma membrane
GO:0006865 - amino acid transport
GO:0007612 - learning

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

681231

SC6A1
Sodium- and chloride-dependent GABA transporter 1

1

1

High-throughput

0.618

High

681246

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

3

High-throughput

0.536

High

61652

KCNB2
Potassium voltage-gated channel subfamily B member 2

1

2

High-throughput

0.479

High

88364

SHAN1
SH3 and multiple ankyrin repeat domains protein 1

1

2

High-throughput

0.479

High

92904

PRRT2
Proline-rich transmembrane protein 2

1

1

High-throughput

0.479

High

102828

G3X9H5
Huntingtin

1

2

High-throughput

0.479

High

250599

LNX1
E3 ubiquitin-protein ligase LNX

1

20

High-throughput

0.479

High

497931

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.479

High

620919

GRIA2
Glutamate receptor 2

1

4

High-throughput

0.479

High

677186

SSR3
Somatostatin receptor type 3

1

3

High-throughput

0.479

High

681232

CALX
Calnexin

1

5

High-throughput

0.479

High

681233

EAA2
Excitatory amino acid transporter 2

1

1

High-throughput

0.479

High

681240

STX1B
Syntaxin-1B

1

15

High-throughput

0.479

High

681241

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

5

High-throughput

0.479

High

681242

VAMP2
Vesicle-associated membrane protein 2

1

3

High-throughput

0.479

High

681243

GDN
Glia-derived nexin

1

1

High-throughput

0.479

High

681259

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

1

High-throughput

0.479

High

681263

DGKG
Diacylglycerol kinase gamma

1

5

High-throughput

0.479

High

681265

LNX2
Ligand of Numb protein X 2

1

20

High-throughput

0.479

High

681266

SYUB
Beta-synuclein

1

6

High-throughput

0.479

High

681272

RTN4
Reticulon-4

1

3

High-throughput

0.479

High

681274

ACBG1
Long-chain-fatty-acid--CoA ligase ACSBG1

1

4

High-throughput

0.479

High

681277

RUFY3
Protein RUFY3

1

1

High-throughput

0.479

High

681280

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

2

High-throughput

0.479

High

681281

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.479

High

681282

E41L3
Band 4.1-like protein 3

1

6

High-throughput

0.479

High

291421

S4A4
Electrogenic sodium bicarbonate cotransporter 1

1

0

High-throughput

0.458

High

543092

GLNA
Glutamine synthetase

1

0

High-throughput

0.458

High

681261

SNP47
Synaptosomal-associated protein 47

1

0

High-throughput

0.458

High

681270

MYO5A
Unconventional myosin-Va

1

0

High-throughput

0.458

High

56850

F1712
Protein FAM171A2

1

1

High-throughput

0.437

High

102618

G3X8Y3

1

1

High-throughput

0.437

High

681234

H15
Histone H1.5

1

1

High-throughput

0.437

High

681238

ABCD3
ATP-binding cassette sub-family D member 3

1

1

High-throughput

0.437

High

681239

RU2A
U2 small nuclear ribonucleoprotein A'

1

5

High-throughput

0.437

High

681244

F171B
Protein FAM171B

1

1

High-throughput

0.437

High

681245

PSD3
PH and SEC7 domain-containing protein 3

1

1

High-throughput

0.437

High

681249

PRDX2
Peroxiredoxin-2

1

1

High-throughput

0.437

High

681250

KTN1
Kinectin

1

2

High-throughput

0.437

High

681251

SERA
D-3-phosphoglycerate dehydrogenase

1

1

High-throughput

0.437

High

681252

RALY
RNA-binding protein Raly

1

1

High-throughput

0.437

High

681254

PITM2
Membrane-associated phosphatidylinositol transfer protein 2

1

1

High-throughput

0.437

High

681255

TNC18
Trinucleotide repeat-containing gene 18 protein

1

1

High-throughput

0.437

High

681258

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

1

High-throughput

0.437

High

681267

FADS1
Acyl-CoA

1

3

High-throughput

0.437

High

681269

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

2

High-throughput

0.437

High

681271

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

1

High-throughput

0.437

High

681273

RRBP1
Ribosome-binding protein 1

1

3

High-throughput

0.437

High

681275

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

1

2

High-throughput

0.437

High

681278

RTN3
Reticulon-3

1

3

High-throughput

0.437

High

498399

GSTM1
Glutathione S-transferase Mu 1

1

0

High-throughput

0.249

Low

525118

SCD2
Stearoyl-CoA desaturase 2

1

0

High-throughput

0.249

Low

681235

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

681236

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.249

Low

681237

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.249

Low

681247

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.249

Low

681248

COPD
Coatomer subunit delta

1

0

High-throughput

0.249

Low

681253

SPKAP
A-kinase anchor protein SPHKAP

1

0

High-throughput

0.249

Low

681256

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

681257

ASGL1
Isoaspartyl peptidase/L-asparaginase

1

0

High-throughput

0.249

Low

681260

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.249

Low

681262

P66B
Transcriptional repressor p66-beta

1

0

High-throughput

0.249

Low

681264

NCALD
Neurocalcin-delta

1

0

High-throughput

0.249

Low

681268

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.249

Low

681276

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.249

Low

681279

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024