Protein: NMDE2
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B)

Gene: NMDE2, Grin2b
Organism: Mus musculus
Interactions: 132
UniProt ID: Q01097

Gene Ontology (top 5):
GO:0001508 - action potential
GO:0001662 - behavioral fear response
GO:0001666 - response to hypoxia
GO:0001701 - in utero embryonic development
GO:0001964 - startle response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

723572

NMDZ1
Glutamate receptor ionotropic, NMDA 1

10

20

Small-scale

0.969

High

723524

NMDE1
Glutamate receptor ionotropic, NMDA 2A

3

18

Small-scale

0.834

High

963716

NMDE2
Glutamate receptor ionotropic, NMDA 2B

3

18

Small-scale

0.805

High

963732

DLG4
Disks large homolog 4

18

20

Small-scale

0.763

High

515226

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

7

15

Small-scale

0.731

High

99963

SYGP1
Ras/Rap GTPase-activating protein SynGAP

5

11

High-throughput

0.714

High

963772

DLGP1
Disks large-associated protein 1

3

12

High-throughput

0.660

High

956894

GRM1
Metabotropic glutamate receptor 1

1

11

High-throughput

0.646

High

963749

DAPK1
Death-associated protein kinase 1

2

20

Small-scale

0.633

High

620944

GRIA2
Glutamate receptor 2

1

18

High-throughput

0.618

High

963724

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

2

10

High-throughput

0.611

High

873170

PTN5
Tyrosine-protein phosphatase non-receptor type 5

2

15

Small-scale

0.595

High

963773

ACTN2
Alpha-actinin-2

2

9

Small-scale

0.594

High

956918

CXAR
Coxsackievirus and adenovirus receptor homolog

1

0

High-throughput

0.586

High

963741

Q6ZWQ9
Myosin, light chain 12A, regulatory, non-sarcomeric

2

3

Small-scale

0.584

High

949266

TNIK
Traf2 and NCK-interacting protein kinase

1

9

High-throughput

0.536

High

963721

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

10

High-throughput

0.536

High

963735

INADL
InaD-like protein

1

20

Small-scale

0.527

High

571855

HS71B
Heat shock 70 kDa protein 1B

1

2

High-throughput

0.500

High

659449

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

15

High-throughput

0.500

High

719298

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

14

High-throughput

0.500

High

760442

DYN1
Dynamin-1

1

1

High-throughput

0.500

High

804015

NSF
Vesicle-fusing ATPase

1

5

High-throughput

0.500

High

930601

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

5

High-throughput

0.500

High

933716

TBA1A
Tubulin alpha-1A chain

1

9

High-throughput

0.500

High

936175

DLG3
Disks large homolog 3

1

20

High-throughput

0.500

High

963764

NETO1
Neuropilin and tolloid-like protein 1

1

7

Small-scale

0.500

High

963769

DLG2
Disks large homolog 2

1

20

High-throughput

0.500

High

56852

F1712
Protein FAM171A2

1

2

High-throughput

0.479

High

57838

KALRN
Kalirin

1

20

High-throughput

0.479

High

61653

KCNB2
Potassium voltage-gated channel subfamily B member 2

1

3

High-throughput

0.479

High

930563

KPCG
Protein kinase C gamma type

1

13

High-throughput

0.479

High

930583

RALA
Ras-related protein Ral-A

1

6

High-throughput

0.479

High

930622

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

6

High-throughput

0.479

High

932485

ACTC
Actin, alpha cardiac muscle 1

1

5

High-throughput

0.479

High

934622

KPCB
Protein kinase C beta type

1

13

High-throughput

0.479

High

88320

AKAP5
A-kinase anchor protein 5

1

1

High-throughput

0.479

High

102993

G3X9H5
Huntingtin

1

3

High-throughput

0.479

High

193584

CTND2
Catenin delta-2

1

7

High-throughput

0.479

High

223160

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

3

High-throughput

0.479

High

291571

DHCR7
7-dehydrocholesterol reductase

1

1

High-throughput

0.479

High

292486

LIN7C
Protein lin-7 homolog C

1

20

Small-scale

0.479

High

397210

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

6

High-throughput

0.479

High

403431

SRC
Proto-oncogene tyrosine-protein kinase Src

1

6

High-throughput

0.479

High

434799

SPTA1
Spectrin alpha chain, erythrocytic 1

1

17

High-throughput

0.479

High

530204

NCAM1
Neural cell adhesion molecule 1

1

4

High-throughput

0.479

High

544707

CADH2
Cadherin-2

1

2

High-throughput

0.479

High

554900

KPCE
Protein kinase C epsilon type

1

12

High-throughput

0.479

High

578250

KS6A1
Ribosomal protein S6 kinase alpha-1

1

6

High-throughput

0.479

High

578261

KS6A3
Ribosomal protein S6 kinase alpha-3

1

10

High-throughput

0.479

High

592764

MTAP2
Microtubule-associated protein 2

1

3

High-throughput

0.479

High

643080

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

11

High-throughput

0.479

High

677636

CTND1
Catenin delta-1

1

8

High-throughput

0.479

High

679422

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

4

High-throughput

0.479

High

682465

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

6

High-throughput

0.479

High

823532

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

892721

CDC42
Cell division control protein 42 homolog

1

2

High-throughput

0.479

High

919690

RAP1A
Ras-related protein Rap-1A

1

9

High-throughput

0.479

High

925785

RAC1
Ras-related C3 botulinum toxin substrate 1

1

2

High-throughput

0.479

High

926400

MK01
Mitogen-activated protein kinase 1

1

3

High-throughput

0.479

High

926534

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

3

High-throughput

0.479

High

963717

CTNB1
Catenin beta-1

1

4

High-throughput

0.479

High

963718

NF1
Neurofibromin

1

11

High-throughput

0.479

High

963719

F171B
Protein FAM171B

1

2

High-throughput

0.479

High

963720

PSD3
PH and SEC7 domain-containing protein 3

1

1

High-throughput

0.479

High

963722

TEN4
Teneurin-4

1

2

High-throughput

0.479

High

963723

CDKL5
Cyclin-dependent kinase-like 5

1

8

High-throughput

0.479

High

963725

SRC8
Src substrate cortactin

1

10

High-throughput

0.479

High

963726

PPP5
Serine/threonine-protein phosphatase 5

1

8

High-throughput

0.479

High

963727

SHC3
SHC-transforming protein 3

1

13

Small-scale

0.479

High

963729

RASH
GTPase HRas

1

6

High-throughput

0.479

High

963730

DSG1A
Desmoglein-1-alpha

1

4

High-throughput

0.479

High

963731

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

3

High-throughput

0.479

High

963733

MK03
Mitogen-activated protein kinase 3

1

3

High-throughput

0.479

High

963734

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

12

High-throughput

0.479

High

963736

CLH1
Clathrin heavy chain 1

1

4

High-throughput

0.479

High

963737

DLGP3
Disks large-associated protein 3

1

12

High-throughput

0.479

High

963738

NEB2
Neurabin-2

1

20

High-throughput

0.479

High

963739

KCD12
BTB/POZ domain-containing protein KCTD12

1

2

High-throughput

0.479

High

963740

TAOK2
Serine/threonine-protein kinase TAO2

1

11

High-throughput

0.479

High

963742

AKAP9
A-kinase anchor protein 9

1

9

High-throughput

0.479

High

963743

PLPR4
Phospholipid phosphatase-related protein type 4

1

2

High-throughput

0.479

High

963745

PLPR3
Phospholipid phosphatase-related protein type 3

1

2

High-throughput

0.479

High

963746

PCDH8
Protocadherin-8

1

1

High-throughput

0.479

High

963747

LRRC7
Leucine-rich repeat-containing protein 7

1

4

High-throughput

0.479

High

963748

AGRL3
Adhesion G protein-coupled receptor L3

1

2

High-throughput

0.479

High

963750

SHAN2
SH3 and multiple ankyrin repeat domains protein 2

1

7

High-throughput

0.479

High

963752

RHG32
Rho GTPase-activating protein 32

1

1

Small-scale

0.479

High

963753

DUS4
Dual specificity protein phosphatase 4

1

2

High-throughput

0.479

High

963754

SHC2
SHC-transforming protein 2

1

13

Small-scale

0.479

High

963755

LRC4C
Leucine-rich repeat-containing protein 4C

1

5

High-throughput

0.479

High

963756

MGLYR
Metabotropic glycine receptor

1

4

High-throughput

0.479

High

963757

ELFN1
Protein ELFN1

1

7

High-throughput

0.479

High

963758

PDE10
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

1

1

Small-scale

0.479

High

963765

OTU7A
OTU domain-containing protein 7A

1

1

High-throughput

0.479

High

963766

WASF1
Actin-binding protein WASF1

1

1

High-throughput

0.479

High

963767

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

3

High-throughput

0.479

High

963768

UBAP2
Ubiquitin-associated protein 2

1

2

High-throughput

0.479

High

963771

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

8

High-throughput

0.479

High

963774

FAK2
Protein-tyrosine kinase 2-beta

1

14

High-throughput

0.479

High

963777

SYT11
Synaptotagmin-11

1

2

High-throughput

0.479

High

963778

SEPT6
Septin-6

1

3

High-throughput

0.479

High

963779

ARC
Activity-regulated cytoskeleton-associated protein

1

1

High-throughput

0.479

High

963780

E41L3
Band 4.1-like protein 3

1

9

High-throughput

0.479

High

963781

NOS1
Nitric oxide synthase 1

1

6

High-throughput

0.479

High

963782

SEPT3
Neuronal-specific septin-3

1

3

High-throughput

0.479

High

963783

HOME1
Homer protein homolog 1

1

6

High-throughput

0.479

High

139549

STXB1
Syntaxin-binding protein 1

1

0

High-throughput

0.458

High

567497

AP2A1
AP-2 complex subunit alpha-1

1

0

Small-scale

0.458

High

911591

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

936436

PEBP1
Phosphatidylethanolamine-binding protein 1

1

0

High-throughput

0.458

High

963728

CTNA2
Catenin alpha-2

1

0

High-throughput

0.458

High

291543

KLC2
Kinesin light chain 2

1

5

High-throughput

0.445

High

292193

BSN
Protein bassoon

1

3

High-throughput

0.445

High

519470

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

1

High-throughput

0.445

High

761851

ZO1
Tight junction protein ZO-1

1

20

High-throughput

0.445

High

804940

AINX
Alpha-internexin

1

4

High-throughput

0.445

High

882682

FUS
RNA-binding protein FUS

1

2

High-throughput

0.445

High

936730

TP53B
TP53-binding protein 1

1

2

High-throughput

0.445

High

963744

Q7TMX2
Protein phosphatase 2

1

2

High-throughput

0.445

High

963751

DLG1
Disks large homolog 1

1

20

High-throughput

0.445

High

963762

Q8K2R1
Fam171a1 protein

1

2

High-throughput

0.445

High

963763

DP13A
DCC-interacting protein 13-alpha

1

1

High-throughput

0.445

High

963770

MYO5A
Unconventional myosin-Va

1

6

High-throughput

0.445

High

963775

SRCN1
SRC kinase signaling inhibitor 1

1

4

High-throughput

0.445

High

101582

F8VQL0
Hepatocyte growth factor receptor

1

8

High-throughput

0.437

High

812841

PA24A
Cytosolic phospholipase A2

1

4

High-throughput

0.437

High

963759

SEPT8
Septin-8

1

3

High-throughput

0.437

High

963776

H2AY
Core histone macro-H2A.1

1

2

High-throughput

0.437

High

963761

Q8K2I5
Cltc protein

1

4

High-throughput

0.407

High

963760

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024