Protein: JUN
Transcription factor Jun (AH119) (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A)

Gene: JUN
Organism: Mus musculus
Interactions: 77
UniProt ID: P05627

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

345596

FOS
Protein c-Fos

7

20

Small-scale

0.957

High

404100

JUN
Transcription factor Jun

2

19

Small-scale

0.775

High

404127

MAFB
Transcription factor MafB

2

20

Small-scale

0.757

High

404155

MK08
Mitogen-activated protein kinase 8

11

20

Small-scale

0.755

High

404142

ATF3
Cyclic AMP-dependent transcription factor ATF-3

2

20

Small-scale

0.754

High

404138

ATF4
Cyclic AMP-dependent transcription factor ATF-4

2

8

Small-scale

0.743

High

404122

NOS2
Nitric oxide synthase, inducible

4

3

Small-scale

0.676

High

404116

SPI1
Transcription factor PU.1

3

20

Small-scale

0.650

High

404113

FOSB
Protein FosB

1

20

Small-scale

0.618

High

404133

CREB1
Cyclic AMP-responsive element-binding protein 1

1

18

Small-scale

0.618

High

404136

TF65
Transcription factor p65

1

20

Small-scale

0.618

High

404156

SIR1
NAD-dependent protein deacetylase sirtuin-1

2

4

Small-scale

0.612

High

404102

TNFA
Tumor necrosis factor

2

6

Small-scale

0.601

High

404124

STAT3
Signal transducer and activator of transcription 3

2

7

Small-scale

0.586

High

404110

IL1B
Interleukin-1 beta

2

2

Small-scale

0.584

High

404101

GCR
Glucocorticoid receptor

1

18

Small-scale

0.536

High

404145

CDK6
Cyclin-dependent kinase 6

1

2

Small-scale

0.536

High

353094

IL2RA
Interleukin-2 receptor subunit alpha

2

2

Small-scale

0.533

High

404125

HHEX
Hematopoietically-expressed homeobox protein Hhex

1

14

Small-scale

0.527

High

378805

GRAB
Granzyme B(G,H)

1

3

Small-scale

0.515

High

404105

ITB1
Integrin beta-1

1

2

High-throughput

0.501

High

404152

CASP9
Caspase-9

1

2

Small-scale

0.501

High

404115

MECOM
Histone-lysine N-methyltransferase MECOM

1

11

Small-scale

0.500

High

139683

BARX2
Homeobox protein BarH-like 2

1

15

High-throughput

0.481

High

193511

CSN5
COP9 signalosome complex subunit 5

1

8

Small-scale

0.481

High

404104

HXC8
Homeobox protein Hox-C8

1

11

Small-scale

0.481

High

404106

HME1
Homeobox protein engrailed-1

1

12

Small-scale

0.481

High

404108

HXA9
Homeobox protein Hox-A9

1

12

Small-scale

0.481

High

404151

SMAD3
Mothers against decapentaplegic homolog 3

1

9

Small-scale

0.481

High

56894

ZEP3
Transcription factor HIVEP3

1

6

Small-scale

0.479

High

70887

EP300
Histone acetyltransferase p300

1

20

High-throughput

0.479

High

140331

PTGDS
Prostaglandin-H2 D-isomerase

1

4

Small-scale

0.479

High

292157

CTBP1
C-terminal-binding protein 1

1

4

High-throughput

0.479

High

292641

SP1
Transcription factor Sp1

1

7

Small-scale

0.479

High

337616

ABL1
Tyrosine-protein kinase ABL1

1

3

Small-scale

0.479

High

348400

MYC
Myc proto-oncogene protein

1

7

Small-scale

0.479

High

352940

IFNG
Interferon gamma

1

5

Small-scale

0.479

High

404103

IL6
Interleukin-6

1

1

Small-scale

0.479

High

404107

CSF1R
Macrophage colony-stimulating factor 1 receptor

1

3

Small-scale

0.479

High

404109

CCL2
C-C motif chemokine 2

1

10

Small-scale

0.479

High

404112

A4
Amyloid-beta precursor protein

1

7

Small-scale

0.479

High

404114

CCL4
C-C motif chemokine 4

1

10

Small-scale

0.479

High

404117

CXL10
C-X-C motif chemokine 10

1

5

Small-scale

0.479

High

404118

CXCL9
C-X-C motif chemokine 9

1

5

Small-scale

0.479

High

404119

ESR1
Estrogen receptor

1

19

Small-scale

0.479

High

404121

DUS1
Dual specificity protein phosphatase 1

1

2

Small-scale

0.479

High

404126

BRCA1
Breast cancer type 1 susceptibility protein homolog

1

15

Small-scale

0.479

High

404134

CTNB1
Catenin beta-1

1

6

Small-scale

0.479

High

404135

CCL7
C-C motif chemokine 7

1

10

Small-scale

0.479

High

404137

SOX8
Transcription factor SOX-8

1

19

Small-scale

0.479

High

404139

PRDM1
PR domain zinc finger protein 1

1

11

Small-scale

0.479

High

404143

SOX17
Transcription factor SOX-17

1

18

Small-scale

0.479

High

404144

CCL12
C-C motif chemokine 12

1

10

Small-scale

0.479

High

404146

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

16

High-throughput

0.479

High

404147

H2B1B
Histone H2B type 1-B

1

7

Small-scale

0.479

High

404148

SMCA2
Probable global transcription activator SNF2L2

1

11

Small-scale

0.479

High

404150

Q8BK32
Nuclear receptor corepressor 1

1

3

Small-scale

0.479

High

404153

ITCH
E3 ubiquitin-protein ligase Itchy

1

5

Small-scale

0.479

High

404157

IL23A
Interleukin-23 subunit alpha

1

1

Small-scale

0.479

High

404158

TLR9
Toll-like receptor 9

1

1

Small-scale

0.479

High

404160

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

Small-scale

0.479

High

352953

IL1A
Interleukin-1 alpha

1

0

Small-scale

0.458

High

404120

MFGM
Lactadherin

1

0

Small-scale

0.458

High

404131

IL18
Interleukin-18

1

0

Small-scale

0.458

High

404140

ITF2
Transcription factor 4

1

0

Small-scale

0.458

High

404141

BAG1
BAG family molecular chaperone regulator 1

1

0

Small-scale

0.458

High

404149

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

Small-scale

0.458

High

404154

SNPC5
snRNA-activating protein complex subunit 5

1

1

Small-scale

0.457

High

404128

TDG
G/T mismatch-specific thymine DNA glycosylase

1

1

Small-scale

0.457

High

404129

TPM1
Tropomyosin alpha-1 chain

1

11

Small-scale

0.457

High

101504

F8VQ72
Mitogen-activated protein kinase kinase kinase 1

1

3

Small-scale

0.437

High

404111

CXCL2
C-X-C motif chemokine 2

1

5

Small-scale

0.437

High

404123

MMP13
Collagenase 3

1

4

Small-scale

0.437

High

404132

I12R2
Interleukin-12 receptor subunit beta-2

1

4

Small-scale

0.437

High

404159

Q9JM08
Histone deacetylase

1

14

Small-scale

0.437

High

404130

TPM2
Tropomyosin beta chain

1

11

Small-scale

0.417

High


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Last updated: 15 Jul 2024