Protein: CEBPA
CCAAT/enhancer-binding protein alpha (C/EBP alpha)

Gene: CEBPA
Organism: Mus musculus
Interactions: 144
UniProt ID: P53566

Gene Ontology (top 5):
GO:0000050 - urea cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

655995

CEBPB
CCAAT/enhancer-binding protein beta

4

19

Small-scale

0.878

High

862807

JDP2
Jun dimerization protein 2

1

20

High-throughput

0.698

High

673229

CDK4
Cyclin-dependent kinase 4

3

6

Small-scale

0.680

High

862806

CDK2
Cyclin-dependent kinase 2

2

5

Small-scale

0.624

High

862791

CEBPA
CCAAT/enhancer-binding protein alpha

1

19

Small-scale

0.618

High

727206

DDIT3
DNA damage-inducible transcript 3 protein

2

15

Small-scale

0.614

High

140244

HDAC1
Histone deacetylase 1

2

10

Small-scale

0.594

High

862794

WDR5
WD repeat-containing protein 5

2

14

Small-scale

0.594

High

489478

BCL2
Apoptosis regulator Bcl-2

2

4

Small-scale

0.584

High

567548

SPI1
Transcription factor PU.1

2

14

Small-scale

0.584

High

862897

PSD10
26S proteasome non-ATPase regulatory subunit 10

2

7

Small-scale

0.584

High

862802

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

4

Small-scale

0.561

High

862892

FOXO1
Forkhead box protein O1

1

11

Small-scale

0.534

High

527139

RB
Retinoblastoma-associated protein

1

9

Small-scale

0.501

High

862856

TRIB2
Tribbles homolog 2

1

10

Small-scale

0.501

High

862857

TRIB1
Tribbles homolog 1

1

11

Small-scale

0.501

High

862837

KDM1A
Lysine-specific histone demethylase 1A

1

3

Small-scale

0.500

High

862850

RBBP5
Retinoblastoma-binding protein 5

1

9

Small-scale

0.500

High

862869

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

9

Small-scale

0.500

High

862877

DPY30
Protein dpy-30 homolog

1

1

Small-scale

0.500

High

60478

A5D6Q2
Ncoa3 protein

1

16

Small-scale

0.479

High

70906

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.479

High

102329

G3UWZ0
Bromodomain adjacent to zinc finger domain 1A

1

20

Small-scale

0.479

High

140138

NCOA3
Nuclear receptor coactivator 3

1

16

Small-scale

0.479

High

193316

PININ
Pinin

1

3

Small-scale

0.479

High

223104

SAP18
Histone deacetylase complex subunit SAP18

1

1

Small-scale

0.479

High

291831

ZFR
Zinc finger RNA-binding protein

1

12

Small-scale

0.479

High

348410

MYC
Myc proto-oncogene protein

1

20

Small-scale

0.479

High

435817

TRFL
Lactotransferrin

1

4

Small-scale

0.479

High

444956

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

Small-scale

0.479

High

470228

H2AZ
Histone H2A.Z

1

9

Small-scale

0.479

High

506506

PERM
Myeloperoxidase

1

3

Small-scale

0.479

High

509477

CDK1
Cyclin-dependent kinase 1

1

4

Small-scale

0.479

High

539727

LMNB1
Lamin-B1

1

12

Small-scale

0.479

High

558496

DDX3L
Putative ATP-dependent RNA helicase Pl10

1

7

Small-scale

0.479

High

588707

BIP
Endoplasmic reticulum chaperone BiP

1

5

Small-scale

0.479

High

603924

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

1

3

High-throughput

0.479

High

673181

CCND3
G1/S-specific cyclin-D3

1

2

Small-scale

0.479

High

770714

CSF3R
Granulocyte colony-stimulating factor receptor

1

5

Small-scale

0.479

High

781134

LEP
Leptin

1

2

Small-scale

0.479

High

786514

STAT3
Signal transducer and activator of transcription 3

1

8

Small-scale

0.479

High

831947

MCM4
DNA replication licensing factor MCM4

1

9

Small-scale

0.479

High

849657

CCR2
C-C chemokine receptor type 2

1

2

Small-scale

0.479

High

862792

CEBPZ
CCAAT/enhancer-binding protein zeta

1

1

Small-scale

0.479

High

862795

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

4

Small-scale

0.479

High

862796

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

4

Small-scale

0.479

High

862797

RS14
Small ribosomal subunit protein uS11

1

1

Small-scale

0.479

High

862798

RS4X
Small ribosomal subunit protein eS4

1

1

Small-scale

0.479

High

862799

RS25
Small ribosomal subunit protein eS25

1

1

Small-scale

0.479

High

862800

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

10

Small-scale

0.479

High

862801

RS3
Small ribosomal subunit protein uS3

1

1

Small-scale

0.479

High

862803

IMB1
Importin subunit beta-1

1

7

Small-scale

0.479

High

862804

HDAC2
Histone deacetylase 2

1

10

Small-scale

0.479

High

862808

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

9

Small-scale

0.479

High

862809

TOP2A
DNA topoisomerase 2-alpha

1

4

Small-scale

0.479

High

862810

TERA
Transitional endoplasmic reticulum ATPase

1

2

Small-scale

0.479

High

862811

TOP1
DNA topoisomerase 1

1

2

Small-scale

0.479

High

862812

SOX8
Transcription factor SOX-8

1

20

Small-scale

0.479

High

862813

COE1
Transcription factor COE1

1

2

Small-scale

0.479

High

862814

HP1B3
Heterochromatin protein 1-binding protein 3

1

1

Small-scale

0.479

High

862815

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

4

Small-scale

0.479

High

862816

LBR
Delta(14)-sterol reductase LBR

1

1

Small-scale

0.479

High

862817

SMU1
WD40 repeat-containing protein SMU1

1

13

Small-scale

0.479

High

862818

HDGR2
Hepatoma-derived growth factor-related protein 2

1

15

Small-scale

0.479

High

862819

ELNE
Neutrophil elastase

1

8

Small-scale

0.479

High

862822

SIN3A
Paired amphipathic helix protein Sin3a

1

4

Small-scale

0.479

High

862824

KLF3
Krueppel-like factor 3

1

17

Small-scale

0.479

High

862825

ADIPO
Adiponectin

1

2

Small-scale

0.479

High

862826

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

5

Small-scale

0.479

High

862827

EWS
RNA-binding protein EWS

1

6

Small-scale

0.479

High

862828

RAD21
Double-strand-break repair protein rad21 homolog

1

1

Small-scale

0.479

High

862829

MCM7
DNA replication licensing factor MCM7

1

9

Small-scale

0.479

High

862830

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

9

Small-scale

0.479

High

862831

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

10

Small-scale

0.479

High

862832

RBL1
Retinoblastoma-like protein 1

1

9

Small-scale

0.479

High

862833

NOP58
Nucleolar protein 58

1

5

Small-scale

0.479

High

862834

SMCA2
Probable global transcription activator SNF2L2

1

14

Small-scale

0.479

High

862835

RRP5
Protein RRP5 homolog

1

9

Small-scale

0.479

High

862839

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

3

Small-scale

0.479

High

862840

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

3

Small-scale

0.479

High

862843

MED23
Mediator of RNA polymerase II transcription subunit 23

1

2

Small-scale

0.479

High

862844

SAFB2
Scaffold attachment factor B2

1

9

Small-scale

0.479

High

862845

Q80ZH7
DNA ligase

1

2

Small-scale

0.479

High

862848

PUM3
Pumilio homolog 3

1

2

Small-scale

0.479

High

862849

THOC5
THO complex subunit 5 homolog

1

1

Small-scale

0.479

High

862851

TCRG1
Transcription elongation regulator 1

1

18

Small-scale

0.479

High

862852

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

7

Small-scale

0.479

High

862853

NAT10
RNA cytidine acetyltransferase

1

1

Small-scale

0.479

High

862854

MATR3
Matrin-3

1

7

Small-scale

0.479

High

862855

DDX18
ATP-dependent RNA helicase DDX18

1

12

Small-scale

0.479

High

862858

DDX54
ATP-dependent RNA helicase DDX54

1

14

Small-scale

0.479

High

862860

RFC3
Replication factor C subunit 3

1

8

Small-scale

0.479

High

862861

THOC1
THO complex subunit 1

1

1

Small-scale

0.479

High

862863

MYH9
Myosin-9

1

1

Small-scale

0.479

High

862864

RBM39
RNA-binding protein 39

1

13

Small-scale

0.479

High

862865

IF4A3
Eukaryotic initiation factor 4A-III

1

13

Small-scale

0.479

High

862866

DDX1
ATP-dependent RNA helicase DDX1

1

13

Small-scale

0.479

High

862868

SHRPN
Sharpin

1

1

Small-scale

0.479

High

862870

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

4

Small-scale

0.479

High

862874

RFC4
Replication factor C subunit 4

1

8

Small-scale

0.479

High

862875

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

6

Small-scale

0.479

High

862876

NXF1
Nuclear RNA export factor 1

1

1

Small-scale

0.479

High

862878

RNPS1
RNA-binding protein with serine-rich domain 1

1

8

Small-scale

0.479

High

862879

RETN
Resistin

1

1

Small-scale

0.479

High

862880

BHE41
Class E basic helix-loop-helix protein 41

1

5

Small-scale

0.479

High

862881

DDX47
Probable ATP-dependent RNA helicase DDX47

1

14

Small-scale

0.479

High

862882

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

8

Small-scale

0.479

High

862883

STAG1
Cohesin subunit SA-1

1

1

Small-scale

0.479

High

862884

NOP56
Nucleolar protein 56

1

5

Small-scale

0.479

High

862888

FL2D
Pre-mRNA-splicing regulator WTAP

1

1

Small-scale

0.479

High

862889

BRD4
Bromodomain-containing protein 4

1

12

Small-scale

0.479

High

862890

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

3

Small-scale

0.479

High

862891

MTA2
Metastasis-associated protein MTA2

1

9

Small-scale

0.479

High

862893

SRBP1
Sterol regulatory element-binding protein 1

1

20

Small-scale

0.479

High

862894

RFC2
Replication factor C subunit 2

1

9

Small-scale

0.479

High

862895

BUB3
Mitotic checkpoint protein BUB3

1

13

Small-scale

0.479

High

111389

J3QK52
NOC2 like nucleolar associated transcriptional repressor

1

0

Small-scale

0.458

High

862793

RL27
Large ribosomal subunit protein eL27

1

0

Small-scale

0.458

High

862820

NPA1P
Nucleolar pre-ribosomal-associated protein 1

1

0

Small-scale

0.458

High

862821

NOL10
Nucleolar protein 10

1

0

Small-scale

0.458

High

862836

RRP12
RRP12-like protein

1

0

Small-scale

0.458

High

862838

RS9
Small ribosomal subunit protein uS4

1

0

Small-scale

0.458

High

862841

INT7
Integrator complex subunit 7

1

0

Small-scale

0.458

High

862859

INT13
Integrator complex subunit 13

1

0

Small-scale

0.458

High

862862

NOL6
Nucleolar protein 6

1

0

Small-scale

0.458

High

862867

NCOA5
Nuclear receptor coactivator 5

1

0

Small-scale

0.458

High

862873

STEA4
Metalloreductase STEAP4

1

0

Small-scale

0.458

High

862886

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

0

Small-scale

0.458

High

56933

PRD16
Histone-lysine N-methyltransferase PRDM16

1

9

Small-scale

0.445

High

82751

B9EKJ1
Spna2 protein

1

9

Small-scale

0.437

High

192618

SRSF5
Serine/arginine-rich splicing factor 5

1

12

Small-scale

0.437

High

378811

GRAB
Granzyme B(G,H)

1

4

Small-scale

0.437

High

862805

SRSF3
Serine/arginine-rich splicing factor 3

1

17

Small-scale

0.437

High

862823

MYL6
Myosin light polypeptide 6

1

4

Small-scale

0.437

High

862847

NUP93
Nuclear pore complex protein Nup93

1

2

Small-scale

0.437

High

862871

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

Small-scale

0.437

High

862885

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

14

Small-scale

0.437

High

862887

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

Small-scale

0.437

High

862348

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

0

Small-scale

0.249

Low

862842

MOGS
Mannosyl-oligosaccharide glucosidase

1

0

Small-scale

0.249

Low

862846

NU107
Nuclear pore complex protein Nup107

1

0

Small-scale

0.249

Low

862872

P5CR2
Pyrroline-5-carboxylate reductase 2

1

0

Small-scale

0.249

Low

862896

NU160
Nuclear pore complex protein Nup160

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024