Protein: SMAD4
Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (SMAD family member 4) (SMAD 4) (Smad4)

Gene: SMAD4
Organism: Mus musculus
Interactions: 41
UniProt ID: P97471

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

956549

SMAD3
Mothers against decapentaplegic homolog 3

8

18

Small-scale

0.958

High

956545

SMAD2
Mothers against decapentaplegic homolog 2

6

18

Small-scale

0.935

High

936603

SMAD1
Mothers against decapentaplegic homolog 1

2

19

Small-scale

0.737

High

956542

SKI
Ski oncogene

1

16

Small-scale

0.665

High

956495

SMAD5
Mothers against decapentaplegic homolog 5

1

19

Small-scale

0.618

High

956534

SMAD4
Mothers against decapentaplegic homolog 4

1

18

Small-scale

0.618

High

956537

GATA4
Transcription factor GATA-4

1

8

Small-scale

0.573

High

223180

TLX3
T-cell leukemia homeobox protein 3

1

10

High-throughput

0.541

High

885725

FOXP1
Forkhead box protein P1

1

9

High-throughput

0.541

High

653456

LEF1
Lymphoid enhancer-binding factor 1

1

20

Small-scale

0.515

High

956541

FSHB
Follitropin subunit beta

1

2

Small-scale

0.515

High

139675

PAR3
Proteinase-activated receptor 3

1

3

Small-scale

0.501

High

844412

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

19

Small-scale

0.501

High

956535

GATA5
Transcription factor GATA-5

1

8

Small-scale

0.501

High

956543

GATA6
Transcription factor GATA-6

1

8

Small-scale

0.501

High

956547

ERBIN
Erbin

1

10

Small-scale

0.501

High

817035

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

Small-scale

0.480

High

956551

HOP
Homeodomain-only protein

1

0

Small-scale

0.479

High

56938

PRD16
Histone-lysine N-methyltransferase PRDM16

1

13

Small-scale

0.479

High

140253

HDAC1
Histone deacetylase 1

1

12

Small-scale

0.479

High

250969

PKNX1
Homeobox protein PKNOX1

1

11

Small-scale

0.479

High

435994

CO3A1

1

16

Small-scale

0.479

High

454952

CADH1
Cadherin-1

1

4

Small-scale

0.479

High

503173

CO1A1
Collagen alpha-1(I) chain

1

16

Small-scale

0.479

High

784123

PBX1
Pre-B-cell leukemia transcription factor 1

1

9

Small-scale

0.479

High

956536

SNAI1
Zinc finger protein SNAI1

1

6

Small-scale

0.479

High

956538

SF3B2
Splicing factor 3B subunit 2

1

5

Small-scale

0.479

High

956539

FBW1A
F-box/WD repeat-containing protein 1A

1

5

Small-scale

0.479

High

956540

SIN3A
Paired amphipathic helix protein Sin3a

1

1

Small-scale

0.479

High

956544

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

7

Small-scale

0.479

High

956546

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

3

Small-scale

0.479

High

956548

Q8BTS0
Probable ATP-dependent RNA helicase DDX5

1

10

Small-scale

0.479

High

956552

PEX6
Peroxisomal ATPase PEX6

1

5

Small-scale

0.479

High

956553

ZMYM2
Zinc finger MYM-type protein 2

1

5

Small-scale

0.479

High

956554

4ET
Eukaryotic translation initiation factor 4E transporter

1

4

Small-scale

0.479

High

472974

KGP1
cGMP-dependent protein kinase 1

1

14

Small-scale

0.445

High

956555

GTF2I
General transcription factor II-I

1

3

Small-scale

0.445

High

291323

CO5A1

1

16

Small-scale

0.437

High

371803

CFAD
Complement factor D

1

2

High-throughput

0.437

High

956550

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024