Protein: EHMT2
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Protein G9a)

Gene: EHMT2
Organism: Mus musculus
Interactions: 69
UniProt ID: Q9Z148

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0001222 - transcription corepressor binding
GO:0002039 - p53 binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1265660

EED
Polycomb protein EED

2

16

Small-scale

0.754

High

1125434

EHMT1
Histone-lysine N-methyltransferase EHMT1

2

15

Small-scale

0.737

High

949433

TNIK
Traf2 and NCK-interacting protein kinase

1

14

High-throughput

0.691

High

936656

EZH1
Histone-lysine N-methyltransferase EZH1

1

18

Small-scale

0.665

High

1142301

EZH2
Histone-lysine N-methyltransferase EZH2

1

17

Small-scale

0.665

High

952777

H33
Histone H3.3

1

20

Small-scale

0.647

High

1112138

MPP8
M-phase phosphoprotein 8

1

16

Small-scale

0.618

High

1141320

CSK21
Casein kinase II subunit alpha

1

6

Small-scale

0.618

High

1141954

RBBP4
Histone-binding protein RBBP4

1

7

Small-scale

0.618

High

1257482

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

9

Small-scale

0.618

High

1322370

PALLD
Palladin

1

5

Small-scale

0.618

High

1378270

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

14

Small-scale

0.618

High

1193529

SUZ12
Polycomb protein Suz12

1

0

Small-scale

0.586

High

949963

CBX1
Chromobox protein homolog 1

2

20

Small-scale

0.584

High

1322180

Q9DCC5
Cbx3 protein

2

20

Small-scale

0.584

High

291740

DNM3A
DNA

1

8

Small-scale

0.578

High

291753

DNM3B
DNA

1

8

Small-scale

0.578

High

111414

J3QPN0
Zinc finger protein 518B

1

6

Small-scale

0.561

High

991038

NFE2
Transcription factor NF-E2 45 kDa subunit

1

1

Small-scale

0.536

High

1194729

NANOG
Homeobox protein NANOG

1

16

High-throughput

0.536

High

56973

PRD16
Histone-lysine N-methyltransferase PRDM16

1

4

Small-scale

0.501

High

1321845

DNM3L
DNA

1

8

Small-scale

0.501

High

444991

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

Small-scale

0.500

High

60503

A5D6Q2
Ncoa3 protein

1

4

High-throughput

0.481

High

69864

ZN462
Zinc finger protein 462

1

4

Small-scale

0.479

High

70614

Z518A
Zinc finger protein 518A

1

8

Small-scale

0.479

High

93313

ZN568
Zinc finger protein 568

1

1

Small-scale

0.479

High

93740

E9QA23
Zinc finger protein 644

1

9

Small-scale

0.479

High

250556

GFI1B
Zinc finger protein Gfi-1b

1

8

Small-scale

0.479

High

291346

WIZ
Protein Wiz

1

10

Small-scale

0.479

High

453079

HXA9
Homeobox protein Hox-A9

1

9

Small-scale

0.479

High

533924

DNMT1
DNA

1

13

Small-scale

0.479

High

644533

TWST1
Twist-related protein 1

1

6

High-throughput

0.479

High

886514

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

5

Small-scale

0.479

High

970689

MTF2
Metal-response element-binding transcription factor 2

1

4

Small-scale

0.479

High

1112368

MIER2
Mesoderm induction early response protein 2

1

13

Small-scale

0.479

High

1141185

PRDM1
PR domain zinc finger protein 1

1

3

Small-scale

0.479

High

1142055

NCOA2
Nuclear receptor coactivator 2

1

5

Small-scale

0.479

High

1142741

ERR2
Steroid hormone receptor ERR2

1

16

High-throughput

0.479

High

1143050

CBX5
Chromobox protein homolog 5

1

20

Small-scale

0.479

High

1144976

TFE3
Transcription factor E3

1

3

High-throughput

0.479

High

1160053

MBTD1
MBT domain-containing protein 1

1

5

Small-scale

0.479

High

1169599

LCOR
Ligand-dependent corepressor

1

2

Small-scale

0.479

High

1169805

KDM1A
Lysine-specific histone demethylase 1A

1

7

High-throughput

0.479

High

1186802

MCAF1
Activating transcription factor 7-interacting protein 1

1

13

Small-scale

0.479

High

1206863

HIRP3
HIRA-interacting protein 3

1

1

Small-scale

0.479

High

1207114

Q8BPK8
Agenet-like domain-containing protein

1

3

High-throughput

0.479

High

1207523

POGZ
Pogo transposable element with ZNF domain

1

6

Small-scale

0.479

High

1225199

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

14

Small-scale

0.479

High

1225256

LN28A
Protein lin-28 homolog A

1

1

Small-scale

0.479

High

1225273

MTA1
Metastasis-associated protein MTA1

1

13

Small-scale

0.479

High

1246780

ATF7
Cyclic AMP-dependent transcription factor ATF-7

1

4

Small-scale

0.479

High

1265062

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

6

Small-scale

0.479

High

1322051

CDYL2
Chromodomain Y-like protein 2

1

10

Small-scale

0.479

High

1376692

CDYL
Chromodomain Y-like protein

1

17

Small-scale

0.479

High

1378271

MBD3
Methyl-CpG-binding domain protein 3

1

2

Small-scale

0.479

High

1225247

I2BPL
Probable E3 ubiquitin-protein ligase IRF2BPL

1

0

Small-scale

0.458

High

1307801

RTF2
Replication termination factor 2

1

0

Small-scale

0.458

High

1337445

CWC15
Spliceosome-associated protein CWC15 homolog

1

0

Small-scale

0.458

High

985530

Q05BA5
Nuclear receptor coactivator

1

3

High-throughput

0.457

High

729611

FMR1
Fragile X messenger ribonucleoprotein 1

1

3

High-throughput

0.445

High

783232

CD27
CD27 antigen

1

5

Small-scale

0.437

High

626885

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

5

High-throughput

0.417

High

352906

IFNB
Interferon beta

1

0

Small-scale

0.249

Low

353100

IL2RA
Interleukin-2 receptor subunit alpha

1

0

Small-scale

0.249

Low

1194469

GLRX5
Glutaredoxin-related protein 5, mitochondrial

1

0

Small-scale

0.249

Low

1246771

SUMF1
Formylglycine-generating enzyme

1

0

Small-scale

0.249

Low

1321750

DENR
Density-regulated protein

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024