Protein: KLF3
Krueppel-like factor 3 (Basic krueppel-like factor) (CACCC-box-binding protein BKLF) (TEF-2)

Gene: KLF3
Organism: Homo sapiens
Interactions: 244
UniProt ID: P57682

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

167149

ZN536
Zinc finger protein 536

2

20

High-throughput

0.754

High

215880

ZBT14
Zinc finger and BTB domain-containing protein 14

2

20

High-throughput

0.754

High

231220

ZEB2
Zinc finger E-box-binding homeobox 2

2

20

High-throughput

0.754

High

260369

ZN217
Zinc finger protein 217

2

20

High-throughput

0.754

High

550352

ZEP1
Zinc finger protein 40

2

20

High-throughput

0.754

High

741004

ZEB1
Zinc finger E-box-binding homeobox 1

2

20

High-throughput

0.754

High

884131

MECOM
Histone-lysine N-methyltransferase MECOM

2

20

High-throughput

0.754

High

884146

PRDM2
PR domain zinc finger protein 2

2

20

High-throughput

0.754

High

884248

PRD16
Histone-lysine N-methyltransferase PRDM16

2

20

High-throughput

0.754

High

884151

FHL3
Four and a half LIM domains protein 3

7

15

Small-scale

0.754

High

881126

CTBP2
C-terminal-binding protein 2

6

14

Small-scale

0.729

High

884150

CTBP1
C-terminal-binding protein 1

4

14

High-throughput

0.699

High

884145

TRAF2
TNF receptor-associated factor 2

4

20

High-throughput

0.698

High

884224

EHMT2
Histone-lysine N-methyltransferase EHMT2

4

20

High-throughput

0.685

High

157886

KLF11
Krueppel-like factor 11

1

20

High-throughput

0.665

High

868399

ATX1
Ataxin-1

3

9

High-throughput

0.650

High

135101

NFIB
Nuclear factor 1 B-type

2

13

High-throughput

0.634

High

884143

NFIA
Nuclear factor 1 A-type

2

16

High-throughput

0.634

High

884183

LHX8
LIM/homeobox protein Lhx8

2

13

High-throughput

0.628

High

443161

NFIC
Nuclear factor 1 C-type

2

20

High-throughput

0.624

High

737286

LONM
Lon protease homolog, mitochondrial

1

3

High-throughput

0.618

High

855892

ZN131
Zinc finger protein 131

1

20

High-throughput

0.618

High

884147

RLF
Zinc finger protein Rlf

1

20

High-throughput

0.618

High

884162

ZFHX3
Zinc finger homeobox protein 3

1

20

High-throughput

0.618

High

884170

ZN423
Zinc finger protein 423

1

15

High-throughput

0.618

High

884212

ZN516
Zinc finger protein 516

1

20

High-throughput

0.618

High

884213

RREB1
Ras-responsive element-binding protein 1

1

19

High-throughput

0.618

High

884238

BC11A
B-cell lymphoma/leukemia 11A

1

20

High-throughput

0.618

High

884243

ZN644
Zinc finger protein 644

1

20

High-throughput

0.618

High

884269

ZN148
Zinc finger protein 148

1

20

High-throughput

0.618

High

884271

ZN281
Zinc finger protein 281

1

20

High-throughput

0.618

High

686550

OTX2
Homeobox protein OTX2

2

11

High-throughput

0.606

High

884267

LHX6
LIM/homeobox protein Lhx6

2

13

High-throughput

0.606

High

884178

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

2

1

High-throughput

0.601

High

232074

KDM1A
Lysine-specific histone demethylase 1A

2

9

High-throughput

0.600

High

278010

PIAS1
E3 SUMO-protein ligase PIAS1

2

2

High-throughput

0.586

High

152621

KMT2D
Histone-lysine N-methyltransferase 2D

2

20

High-throughput

0.584

High

164209

ZN609
Zinc finger protein 609

2

16

High-throughput

0.584

High

183094

KDM6A
Lysine-specific demethylase 6A

2

14

High-throughput

0.584

High

265622

E2F6
Transcription factor E2F6

2

13

High-throughput

0.584

High

266330

TAD2A
Transcriptional adapter 2-alpha

2

16

High-throughput

0.584

High

278251

PIAS2
E3 SUMO-protein ligase PIAS2

2

2

High-throughput

0.584

High

321742

WIZ
Protein Wiz

2

20

High-throughput

0.584

High

473493

ATX1L
Ataxin-1-like

2

9

High-throughput

0.584

High

525301

NR2C1
Nuclear receptor subfamily 2 group C member 1

2

20

High-throughput

0.584

High

727715

SOX5
Transcription factor SOX-5

2

20

High-throughput

0.584

High

823773

NR2C2
Nuclear receptor subfamily 2 group C member 2

2

20

High-throughput

0.584

High

884128

FOXK1
Forkhead box protein K1

2

16

High-throughput

0.584

High

884132

KMT2A
Histone-lysine N-methyltransferase 2A

2

20

High-throughput

0.584

High

884138

RING1
E3 ubiquitin-protein ligase RING1

2

20

High-throughput

0.584

High

884141

EP300
Histone acetyltransferase p300

2

20

High-throughput

0.584

High

884156

ARI5B
AT-rich interactive domain-containing protein 5B

2

20

High-throughput

0.584

High

884172

ARI4B
AT-rich interactive domain-containing protein 4B

2

20

High-throughput

0.584

High

884177

BRM1L
Breast cancer metastasis-suppressor 1-like protein

2

12

High-throughput

0.584

High

884179

TAF3
Transcription initiation factor TFIID subunit 3

2

20

High-throughput

0.584

High

884182

ARID2
AT-rich interactive domain-containing protein 2

2

20

High-throughput

0.584

High

884185

LIN54
Protein lin-54 homolog

2

4

High-throughput

0.584

High

884217

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

18

High-throughput

0.573

High

884241

CPVL
Probable serine carboxypeptidase CPVL

2

5

High-throughput

0.558

High

660446

GRN
Progranulin

2

3

High-throughput

0.549

High

884129

TFAM
Transcription factor A, mitochondrial

1

19

High-throughput

0.536

High

296798

NOL4
Nucleolar protein 4

2

5

High-throughput

0.533

High

884136

MBTD1
MBT domain-containing protein 1

2

13

High-throughput

0.533

High

884180

ZMYM4
Zinc finger MYM-type protein 4

2

20

High-throughput

0.533

High

57017

A2ABF9
Euchromatic histone lysine methyltransferase 2

1

20

High-throughput

0.515

High

281585

WFS1
Wolframin

1

4

High-throughput

0.515

High

349226

RASH
GTPase HRas

1

6

High-throughput

0.515

High

358738

CRYAA
Alpha-crystallin A chain

1

6

High-throughput

0.515

High

791431

HD
Huntingtin

1

9

High-throughput

0.515

High

803460

BAG6
Large proline-rich protein BAG6

1

20

High-throughput

0.515

High

884216

KLK6
Kallikrein-6

1

3

High-throughput

0.515

High

884244

SUV92
Histone-lysine N-methyltransferase SUV39H2

1

18

High-throughput

0.508

High

518624

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.500

High

838742

EMD
Emerin

1

9

High-throughput

0.500

High

884124

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

6

High-throughput

0.500

High

203901

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.493

High

884270

CSEN
Calsenilin

1

0

High-throughput

0.493

High

884135

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

4

High-throughput

0.489

High

884126

UBC9
SUMO-conjugating enzyme UBC9

1

3

High-throughput

0.481

High

65017

SOBP
Sine oculis-binding protein homolog

1

20

High-throughput

0.479

High

124188

TAF4
Transcription initiation factor TFIID subunit 4

1

15

High-throughput

0.479

High

146189

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

High-throughput

0.479

High

165654

SET1A
Histone-lysine N-methyltransferase SETD1A

1

20

High-throughput

0.479

High

168121

TBX3
T-box transcription factor TBX3

1

14

High-throughput

0.479

High

170311

TIF1A
Transcription intermediary factor 1-alpha

1

20

High-throughput

0.479

High

229347

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

20

High-throughput

0.479

High

261454

NCOR1
Nuclear receptor corepressor 1

1

20

High-throughput

0.479

High

267638

TADA3
Transcriptional adapter 3

1

5

High-throughput

0.479

High

267749

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

17

High-throughput

0.479

High

394431

A4
Amyloid-beta precursor protein

1

18

High-throughput

0.479

High

456529

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

4

High-throughput

0.479

High

521242

SKI
Ski oncogene

1

5

High-throughput

0.479

High

585642

TFE3
Transcription factor E3

1

13

High-throughput

0.479

High

594178

MSH3
DNA mismatch repair protein Msh3

1

1

High-throughput

0.479

High

600113

TAF1
Transcription initiation factor TFIID subunit 1

1

20

High-throughput

0.479

High

653535

CALR
Calreticulin

1

3

High-throughput

0.479

High

666473

ARI4A
AT-rich interactive domain-containing protein 4A

1

20

High-throughput

0.479

High

666518

KDM5A
Lysine-specific demethylase 5A

1

7

High-throughput

0.479

High

692118

ELF1
ETS-related transcription factor Elf-1

1

20

High-throughput

0.479

High

718668

PHB1
Prohibitin 1

1

6

High-throughput

0.479

High

846731

SMCA2
Probable global transcription activator SNF2L2

1

20

High-throughput

0.479

High

867846

HIRA
Protein HIRA

1

10

High-throughput

0.479

High

884121

DCAF7
DDB1- and CUL4-associated factor 7

1

9

High-throughput

0.479

High

884122

WDR5
WD repeat-containing protein 5

1

17

High-throughput

0.479

High

884130

FOXK2
Forkhead box protein K2

1

13

High-throughput

0.479

High

884133

TLE1
Transducin-like enhancer protein 1

1

19

High-throughput

0.479

High

884134

TLE3
Transducin-like enhancer protein 3

1

18

High-throughput

0.479

High

884137

GABPA
GA-binding protein alpha chain

1

20

High-throughput

0.479

High

884139

TLE5
TLE family member 5

1

13

High-throughput

0.479

High

884142

BPTF
Nucleosome-remodeling factor subunit BPTF

1

20

High-throughput

0.479

High

884144

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.479

High

884148

TBX2
T-box transcription factor TBX2

1

14

High-throughput

0.479

High

884152

TFDP1
Transcription factor Dp-1

1

3

High-throughput

0.479

High

884153

ZMYM3
Zinc finger MYM-type protein 3

1

20

High-throughput

0.479

High

884155

MEF2D
Myocyte-specific enhancer factor 2D

1

6

High-throughput

0.479

High

884157

RBBP5
Retinoblastoma-binding protein 5

1

14

High-throughput

0.479

High

884158

SSXT
Protein SSXT

1

15

High-throughput

0.479

High

884160

ELF2
ETS-related transcription factor Elf-2

1

20

High-throughput

0.479

High

884161

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

5

High-throughput

0.479

High

884163

TAF12
Transcription initiation factor TFIID subunit 12

1

3

High-throughput

0.479

High

884164

TAF9
Transcription initiation factor TFIID subunit 9

1

7

High-throughput

0.479

High

884168

RFX7
DNA-binding protein RFX7

1

10

High-throughput

0.479

High

884171

PCGF3
Polycomb group RING finger protein 3

1

20

High-throughput

0.479

High

884174

EPC2
Enhancer of polycomb homolog 2

1

10

High-throughput

0.479

High

884175

BCORL
BCL-6 corepressor-like protein 1

1

12

High-throughput

0.479

High

884181

TSH3
Teashirt homolog 3

1

17

High-throughput

0.479

High

884184

NIPBL
Nipped-B-like protein

1

19

High-throughput

0.479

High

884186

NFRKB
Nuclear factor related to kappa-B-binding protein

1

12

High-throughput

0.479

High

884187

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

13

High-throughput

0.479

High

884188

MCAF1
Activating transcription factor 7-interacting protein 1

1

19

High-throughput

0.479

High

884189

BCOR
BCL-6 corepressor

1

20

High-throughput

0.479

High

884190

UBN2
Ubinuclein-2

1

20

High-throughput

0.479

High

884191

POGZ
Pogo transposable element with ZNF domain

1

20

High-throughput

0.479

High

884192

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

20

High-throughput

0.479

High

884193

I2BP2
Interferon regulatory factor 2-binding protein 2

1

4

High-throughput

0.479

High

884194

PCGF5
Polycomb group RING finger protein 5

1

20

High-throughput

0.479

High

884195

PB1
Protein polybromo-1

1

20

High-throughput

0.479

High

884197

P66A
Transcriptional repressor p66-alpha

1

4

High-throughput

0.479

High

884198

I2BP1
Interferon regulatory factor 2-binding protein 1

1

4

High-throughput

0.479

High

884199

FOXP4
Forkhead box protein P4

1

20

High-throughput

0.479

High

884200

ARI3B
AT-rich interactive domain-containing protein 3B

1

20

High-throughput

0.479

High

884201

MGAP
MAX gene-associated protein

1

13

High-throughput

0.479

High

884202

YAF2
YY1-associated factor 2

1

4

High-throughput

0.479

High

884203

ZZZ3
ZZ-type zinc finger-containing protein 3

1

2

High-throughput

0.479

High

884204

RYBP
RING1 and YY1-binding protein

1

4

High-throughput

0.479

High

884206

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

884207

KDM2B
Lysine-specific demethylase 2B

1

12

High-throughput

0.479

High

884208

CHD6
Chromodomain-helicase-DNA-binding protein 6

1

20

High-throughput

0.479

High

884209

MORC4
MORC family CW-type zinc finger protein 4

1

2

High-throughput

0.479

High

884210

GATD1
GATA zinc finger domain-containing protein 1

1

5

High-throughput

0.479

High

884211

P66B
Transcriptional repressor p66-beta

1

4

High-throughput

0.479

High

884214

KAT2A
Histone acetyltransferase KAT2A

1

20

High-throughput

0.479

High

884215

KAT2B
Histone acetyltransferase KAT2B

1

20

High-throughput

0.479

High

884219

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

13

High-throughput

0.479

High

884220

PF21A
PHD finger protein 21A

1

20

High-throughput

0.479

High

884221

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

20

High-throughput

0.479

High

884222

MBD6
Methyl-CpG-binding domain protein 6

1

12

High-throughput

0.479

High

884223

SGF29
SAGA-associated factor 29

1

1

High-throughput

0.479

High

884225

EP400
E1A-binding protein p400

1

20

High-throughput

0.479

High

884226

PHF12
PHD finger protein 12

1

20

High-throughput

0.479

High

884227

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

884228

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

884229

ARI3A
AT-rich interactive domain-containing protein 3A

1

20

High-throughput

0.479

High

884230

PCGF1
Polycomb group RING finger protein 1

1

20

High-throughput

0.479

High

884231

MTA3
Metastasis-associated protein MTA3

1

20

High-throughput

0.479

High

884234

PCGF6
Polycomb group RING finger protein 6

1

20

High-throughput

0.479

High

884235

SP130
Histone deacetylase complex subunit SAP130

1

20

High-throughput

0.479

High

884237

ING2
Inhibitor of growth protein 2

1

20

High-throughput

0.479

High

884239

EPC1
Enhancer of polycomb homolog 1

1

10

High-throughput

0.479

High

884240

FOXP1
Forkhead box protein P1

1

20

High-throughput

0.479

High

884242

ZHX3
Zinc fingers and homeoboxes protein 3

1

20

High-throughput

0.479

High

884245

CSR2B
Cysteine-rich protein 2-binding protein

1

2

High-throughput

0.479

High

884246

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

20

High-throughput

0.479

High

884249

TAF9B
Transcription initiation factor TFIID subunit 9B

1

7

High-throughput

0.479

High

884251

SHCAF
SIN3-HDAC complex-associated factor

1

3

High-throughput

0.479

High

884252

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.479

High

884253

MBIP1
MAP3K12-binding inhibitory protein 1

1

1

High-throughput

0.479

High

884256

RCOR3
REST corepressor 3

1

20

High-throughput

0.479

High

884258

ZRAN1
Ubiquitin thioesterase ZRANB1

1

14

High-throughput

0.479

High

884259

TRPS1
Zinc finger transcription factor Trps1

1

20

High-throughput

0.479

High

884260

ING1
Inhibitor of growth protein 1

1

20

High-throughput

0.479

High

884261

GMEB2
Glucocorticoid modulatory element-binding protein 2

1

12

High-throughput

0.479

High

884262

RCOR1
REST corepressor 1

1

20

High-throughput

0.479

High

884263

ZHX1
Zinc fingers and homeoboxes protein 1

1

20

High-throughput

0.479

High

884264

ZN608
Zinc finger protein 608

1

8

High-throughput

0.479

High

884265

KMT2B
Histone-lysine N-methyltransferase 2B

1

20

High-throughput

0.479

High

884274

NCOR2
Nuclear receptor corepressor 2

1

20

High-throughput

0.479

High

884275

ZHX2
Zinc fingers and homeoboxes protein 2

1

20

High-throughput

0.479

High

218000

PEX1
Peroxisomal ATPase PEX1

1

3

High-throughput

0.470

High

231482

KIF1B
Kinesin-like protein KIF1B

1

5

High-throughput

0.470

High

388345

HSPB1
Heat shock protein beta-1

1

6

High-throughput

0.470

High

609233

FGFR3
Fibroblast growth factor receptor 3

1

5

High-throughput

0.470

High

884120

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

2

High-throughput

0.470

High

884196

Q86V38
Atrophin 1

1

10

High-throughput

0.470

High

884233

NUP58
Nucleoporin p58/p45

1

1

High-throughput

0.470

High

884123

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

0

High-throughput

0.460

High

615528

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.458

High

836698

DNLI3
DNA ligase 3

1

0

High-throughput

0.458

High

884149

GPS2
G protein pathway suppressor 2

1

0

High-throughput

0.458

High

884159

JHD2C
Probable JmjC domain-containing histone demethylation protein 2C

1

0

High-throughput

0.458

High

884173

LIN52
Protein lin-52 homolog

1

0

High-throughput

0.458

High

884205

IN80E
INO80 complex subunit E

1

0

High-throughput

0.458

High

884236

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

0

High-throughput

0.458

High

884268

SATB2
DNA-binding protein SATB2

1

0

High-throughput

0.458

High

418926

TPM3
Tropomyosin alpha-3 chain

1

13

High-throughput

0.457

High

884127

TPM4
Tropomyosin alpha-4 chain

1

11

High-throughput

0.457

High

884176

PREP
Presequence protease, mitochondrial

1

3

High-throughput

0.457

High

884255

GRHL1
Grainyhead-like protein 1 homolog

1

3

High-throughput

0.445

High

279106

ATP5H
ATP synthase subunit d, mitochondrial

1

2

High-throughput

0.437

High

297046

TOM70
Mitochondrial import receptor subunit TOM70

1

9

High-throughput

0.437

High

335081

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

1

High-throughput

0.437

High

364217

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.437

High

390151

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.437

High

393124

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

6

High-throughput

0.437

High

454018

COX6C
Cytochrome c oxidase subunit 6C

1

1

High-throughput

0.437

High

531771

PDIA4
Protein disulfide-isomerase A4

1

7

High-throughput

0.437

High

538175

ENPL
Endoplasmin

1

5

High-throughput

0.437

High

540730

CX6B1
Cytochrome c oxidase subunit 6B1

1

2

High-throughput

0.437

High

671768

PDIA3
Protein disulfide-isomerase A3

1

7

High-throughput

0.437

High

806454

RL28
Large ribosomal subunit protein eL28

1

6

High-throughput

0.437

High

847422

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.437

High

884154

GSE1
Genetic suppressor element 1

1

2

High-throughput

0.437

High

884166

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

1

High-throughput

0.437

High

884167

MIC60
MICOS complex subunit MIC60

1

3

High-throughput

0.437

High

884169

QSER1
Glutamine and serine-rich protein 1

1

20

High-throughput

0.437

High

884218

RL36L
Ribosomal protein eL42-like

1

10

High-throughput

0.437

High

884232

TMED9
Transmembrane emp24 domain-containing protein 9

1

5

High-throughput

0.437

High

884247

FBRS
Probable fibrosin-1

1

4

High-throughput

0.437

High

884250

FBSL
Fibrosin-1-like protein

1

4

High-throughput

0.437

High

884257

ZMYM2
Zinc finger MYM-type protein 2

1

20

High-throughput

0.437

High

884266

RL26L
Ribosomal protein uL24-like

1

11

High-throughput

0.437

High

884272

HYOU1
Hypoxia up-regulated protein 1

1

20

High-throughput

0.437

High

158172

GIPC1
PDZ domain-containing protein GIPC1

1

0

High-throughput

0.268

Low

884254

DDIT4
DNA damage-inducible transcript 4 protein

1

0

High-throughput

0.268

Low

884273

BACE2
Beta-secretase 2

1

0

High-throughput

0.268

Low

87464

MCRI1
Mapk-regulated corepressor-interacting protein 1

1

0

High-throughput

0.249

Low

156481

SCAM3
Secretory carrier-associated membrane protein 3

1

0

High-throughput

0.249

Low

208218

DNPH1
5-hydroxymethyl-dUMP N-hydrolase

1

0

High-throughput

0.249

Low

429309

SAP
Prosaposin

1

0

High-throughput

0.249

Low

505955

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

0

High-throughput

0.249

Low

849014

SSDH
Succinate-semialdehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

884125

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.249

Low

884140

QOR
Quinone oxidoreductase

1

0

High-throughput

0.249

Low

884165

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024