Protein: NPHP4
Nephrocystin-4 (Nephroretinin)

Gene: NPHP4
Organism: Mus musculus
Interactions: 207
UniProt ID: P59240

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005814 - centriole
GO:0005829 - cytosol
GO:0005911 - cell-cell junction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

886835

NPHP1
Nephrocystin-1

1

4

High-throughput

0.590

High

886790

FTM
Protein fantom

1

7

High-throughput

0.586

High

432416

HS90A
Heat shock protein HSP 90-alpha

1

4

High-throughput

0.536

High

565422

HSP72
Heat shock-related 70 kDa protein 2

1

5

High-throughput

0.536

High

886772

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.493

High

886844

Q9Z1R9
Protease, serine 1

1

3

High-throughput

0.489

High

57319

CNTRL
Centriolin

1

5

High-throughput

0.479

High

64268

A6PWA5
PRAME like 25

1

1

High-throughput

0.479

High

69798

B1ARV6
PRAME like 15

1

1

High-throughput

0.479

High

93547

DESP
Desmoplakin

1

4

High-throughput

0.479

High

359435

K1C10
Keratin, type I cytoskeletal 10

1

17

High-throughput

0.479

High

372932

GFAP
Glial fibrillary acidic protein

1

15

High-throughput

0.479

High

376394

K2C1
Keratin, type II cytoskeletal 1

1

13

High-throughput

0.479

High

399086

TBA1B
Tubulin alpha-1B chain

1

6

High-throughput

0.479

High

427715

ANXA2
Annexin A2

1

1

High-throughput

0.479

High

435919

ENPL
Endoplasmin

1

4

High-throughput

0.479

High

440288

NFM
Neurofilament medium polypeptide

1

15

High-throughput

0.479

High

476667

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

1

High-throughput

0.479

High

485978

ANXA1
Annexin A1

1

1

High-throughput

0.479

High

513665

HS90B
Heat shock protein HSP 90-beta

1

4

High-throughput

0.479

High

514318

K2C8
Keratin, type II cytoskeletal 8

1

11

High-throughput

0.479

High

537693

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.479

High

588709

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.479

High

589620

VIME
Vimentin

1

14

High-throughput

0.479

High

621296

CRYAB
Alpha-crystallin B chain

1

1

High-throughput

0.479

High

751907

GRP75
Stress-70 protein, mitochondrial

1

7

High-throughput

0.479

High

886698

ACTB
Actin, cytoplasmic 1

1

3

High-throughput

0.479

High

886699

ACTA
Actin, aortic smooth muscle

1

3

High-throughput

0.479

High

886701

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

1

High-throughput

0.479

High

886702

HSP7C
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.479

High

886704

ACTG
Actin, cytoplasmic 2

1

3

High-throughput

0.479

High

886706

TBA4A
Tubulin alpha-4A chain

1

7

High-throughput

0.479

High

886707

TBA1A
Tubulin alpha-1A chain

1

6

High-throughput

0.479

High

886708

TBB4B
Tubulin beta-4B chain

1

7

High-throughput

0.479

High

886712

PKP1
Plakophilin-1

1

1

High-throughput

0.479

High

886714

TBB5
Tubulin beta-5 chain

1

7

High-throughput

0.479

High

886718

DNAL1
Dynein axonemal light chain 1

1

1

High-throughput

0.479

High

886721

K22E
Keratin, type II cytoskeletal 2 epidermal

1

11

High-throughput

0.479

High

886735

SRC8
Src substrate cortactin

1

1

High-throughput

0.479

High

886737

CAB45
45 kDa calcium-binding protein

1

2

High-throughput

0.479

High

886740

DSG1A
Desmoglein-1-alpha

1

1

High-throughput

0.479

High

886741

K1C14
Keratin, type I cytoskeletal 14

1

14

High-throughput

0.479

High

886742

MYH10
Myosin-10

1

1

High-throughput

0.479

High

886745

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

3

High-throughput

0.479

High

886749

K1C42
Keratin, type I cytoskeletal 42

1

17

High-throughput

0.479

High

886757

FHOD1
FH1/FH2 domain-containing protein 1

1

1

High-throughput

0.479

High

886762

TBB2A
Tubulin beta-2A chain

1

7

High-throughput

0.479

High

886763

ACTN1
Alpha-actinin-1

1

1

High-throughput

0.479

High

886767

FLNB
Filamin-B

1

4

High-throughput

0.479

High

886774

FLNA
Filamin-A

1

4

High-throughput

0.479

High

886779

VP13C
Intermembrane lipid transfer protein VPS13C

1

1

High-throughput

0.479

High

886780

Q8BXZ6
Uncharacterized protein

1

1

High-throughput

0.479

High

886787

FEM1C
Protein fem-1 homolog C

1

2

High-throughput

0.479

High

886797

EPIPL
Epiplakin

1

2

High-throughput

0.479

High

886800

MYH9
Myosin-9

1

1

High-throughput

0.479

High

886802

FLNC
Filamin-C

1

4

High-throughput

0.479

High

886807

SMTN
Smoothelin

1

3

High-throughput

0.479

High

886808

TBB6
Tubulin beta-6 chain

1

7

High-throughput

0.479

High

886810

K2C5
Keratin, type II cytoskeletal 5

1

12

High-throughput

0.479

High

886818

K1C20
Keratin, type I cytoskeletal 20

1

17

High-throughput

0.479

High

886819

TSSK4
Testis-specific serine/threonine-protein kinase 4

1

1

High-throughput

0.479

High

886824

K2C7
Keratin, type II cytoskeletal 7

1

11

High-throughput

0.479

High

886825

TBB3
Tubulin beta-3 chain

1

7

High-throughput

0.479

High

886832

K1C17
Keratin, type I cytoskeletal 17

1

16

High-throughput

0.479

High

886833

PLEC
Plectin

1

4

High-throughput

0.479

High

886837

RPGR
X-linked retinitis pigmentosa GTPase regulator

1

2

Small-scale

0.479

High

886838

MYO1C
Unconventional myosin-Ic

1

1

High-throughput

0.479

High

59035

RGPA2
Ral GTPase-activating protein subunit alpha-2

1

0

High-throughput

0.458

High

59957

GL1D1
Glycosyltransferase 1 domain-containing protein 1

1

0

High-throughput

0.458

High

61638

SAC31
SAC3 domain-containing protein 1

1

0

High-throughput

0.458

High

140008

PKD1
Polycystin-1

1

0

High-throughput

0.458

High

193601

PITM1
Membrane-associated phosphatidylinositol transfer protein 1

1

0

High-throughput

0.458

High

291377

O88325
Alpha-N-acetylglucosaminidase

1

0

High-throughput

0.458

High

525124

GELS
Gelsolin

1

0

High-throughput

0.458

High

544702

CADH2
Cadherin-2

1

0

High-throughput

0.458

High

657162

ACOHC
Cytoplasmic aconitate hydratase

1

0

High-throughput

0.458

High

723830

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.458

High

727680

PRDX1
Peroxiredoxin-1

1

0

High-throughput

0.458

High

780941

ID3
DNA-binding protein inhibitor ID-3

1

0

High-throughput

0.458

High

837399

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

0

High-throughput

0.458

High

884374

PCBP3
Poly(rC)-binding protein 3

1

0

High-throughput

0.458

High

886697

MRTFB
Myocardin-related transcription factor B

1

0

High-throughput

0.458

High

886703

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

886709

F262
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

1

0

High-throughput

0.458

High

886711

DAB1
Disabled homolog 1

1

0

High-throughput

0.458

High

886715

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

0

High-throughput

0.458

High

886716

PLAK
Junction plakoglobin

1

0

High-throughput

0.458

High

886717

EPHA2
Ephrin type-A receptor 2

1

0

High-throughput

0.458

High

886720

ML12B
Myosin regulatory light chain 12B

1

0

High-throughput

0.458

High

886729

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

0

High-throughput

0.458

High

886732

AN13B
Ankyrin repeat domain-containing protein 13B

1

0

High-throughput

0.458

High

886736

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.458

High

886738

ARGI1
Arginase-1

1

0

High-throughput

0.458

High

886744

SRSF2
Serine/arginine-rich splicing factor 2

1

0

High-throughput

0.458

High

886754

SIK3
Serine/threonine-protein kinase SIK3

1

0

High-throughput

0.458

High

886755

SPA24
Spermatogenesis-associated protein 24

1

0

High-throughput

0.458

High

886758

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.458

High

886761

ERI1
3'-5' exoribonuclease 1

1

0

High-throughput

0.458

High

886770

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

0

High-throughput

0.458

High

886771

NUP93
Nuclear pore complex protein Nup93

1

0

High-throughput

0.458

High

886781

RBM4
RNA-binding protein 4

1

0

High-throughput

0.458

High

886785

FXL13
F-box and leucine-rich repeat protein 13

1

0

High-throughput

0.458

High

886786

CPLN1
Ciliogenesis and planar polarity effector 1

1

0

High-throughput

0.458

High

886799

EMAL3
Echinoderm microtubule-associated protein-like 3

1

0

High-throughput

0.458

High

886803

RINI
Ribonuclease inhibitor

1

0

High-throughput

0.458

High

886804

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

886809

KIF2C
Kinesin-like protein KIF2C

1

0

High-throughput

0.458

High

886811

MYO5A
Unconventional myosin-Va

1

0

High-throughput

0.458

High

886815

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.458

High

886820

SPB7
Serpin B7

1

0

High-throughput

0.458

High

886822

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.458

High

886826

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.458

High

886827

GSDMA
Gasdermin-A

1

0

High-throughput

0.458

High

886828

PYGL
Glycogen phosphorylase, liver form

1

0

High-throughput

0.458

High

886829

PAR6G
Partitioning defective 6 homolog gamma

1

0

High-throughput

0.458

High

886834

DREB
Drebrin

1

0

High-throughput

0.458

High

886836

AMFR
E3 ubiquitin-protein ligase AMFR

1

0

High-throughput

0.458

High

886840

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.458

High

886841

OSR1
Protein odd-skipped-related 1

1

0

High-throughput

0.458

High

886842

CDC7
Cell division cycle 7-related protein kinase

1

0

High-throughput

0.458

High

886846

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

0

High-throughput

0.458

High

57500

A2APS1
Nephronophthisis 1

1

4

High-throughput

0.445

High

886766

SPAT7
Spermatogenesis-associated protein 7 homolog

1

1

Small-scale

0.445

High

69797

B1ART2
Vacuolar protein sorting 13D

1

1

High-throughput

0.437

High

82752

B9EKJ1
Spna2 protein

1

4

High-throughput

0.437

High

93756

E9QAH1
Golgin B1

1

3

High-throughput

0.437

High

93895

E9QQ96
non-specific serine/threonine protein kinase

1

1

High-throughput

0.437

High

193544

CALU
Calumenin

1

2

High-throughput

0.437

High

444562

K1C13
Keratin, type I cytoskeletal 13

1

17

High-throughput

0.437

High

839461

K2C6A
Keratin, type II cytoskeletal 6A

1

12

High-throughput

0.437

High

886705

ACTC
Actin, alpha cardiac muscle 1

1

3

High-throughput

0.437

High

886713

KRT86
Keratin, type II cuticular Hb6

1

10

High-throughput

0.437

High

886722

YETS2
YEATS domain-containing protein 2

1

1

High-throughput

0.437

High

886725

K22O
Keratin, type II cytoskeletal 2 oral

1

14

High-throughput

0.437

High

886728

KRT35
Keratin, type I cuticular Ha5

1

16

High-throughput

0.437

High

886734

MYPC2
Myosin-binding protein C, fast-type

1

2

High-throughput

0.437

High

886739

K1C15
Keratin, type I cytoskeletal 15

1

17

High-throughput

0.437

High

886743

KT33B
Keratin, type I cuticular Ha3-II

1

16

High-throughput

0.437

High

886748

Q6IFT3
Keratin Kb40

1

12

High-throughput

0.437

High

886750

K2C1B
Keratin, type II cytoskeletal 1b

1

13

High-throughput

0.437

High

886752

K2C73
Keratin, type II cytoskeletal 73

1

14

High-throughput

0.437

High

886760

Q792Z1
trypsin

1

3

High-throughput

0.437

High

886765

NAV3
Neuron navigator 3

1

6

High-throughput

0.437

High

886773

RCN2
Reticulocalbin-2

1

2

High-throughput

0.437

High

886776

Q8BUJ0
Titin

1

2

High-throughput

0.437

High

886784

CALI
Calicin

1

1

High-throughput

0.437

High

886791

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

3

High-throughput

0.437

High

886792

EP400
E1A-binding protein p400

1

1

High-throughput

0.437

High

886795

ABC8B
ABC-type organic anion transporter ABCA8B

1

1

High-throughput

0.437

High

886796

ABC8A
ABC-type organic anion transporter ABCA8A

1

1

High-throughput

0.437

High

886801

K2C79
Keratin, type II cytoskeletal 79

1

13

High-throughput

0.437

High

886805

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.437

High

886812

KRT82
Keratin, type II cuticular Hb2

1

10

High-throughput

0.437

High

886813

Q9CPN9
Protease, serine 3B

1

3

High-throughput

0.437

High

886814

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

2

High-throughput

0.437

High

886816

ZDH13
Palmitoyltransferase ZDHHC13

1

1

High-throughput

0.437

High

886830

TRY5
Trypsin-5

1

3

High-throughput

0.437

High

886831

FAK2
Protein-tyrosine kinase 2-beta

1

2

Small-scale

0.437

High

886845

K1C16
Keratin, type I cytoskeletal 16

1

15

High-throughput

0.437

High

886696

NPHP4
Nephrocystin-4

1

0

High-throughput

0.426

High

886778

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

0

High-throughput

0.279

Low

57032

MED14
Mediator of RNA polymerase II transcription subunit 14

1

0

High-throughput

0.249

Low

81950

B7ZNL9
TatD DNase domain containing 2

1

0

High-throughput

0.249

Low

88397

D3Z3J7
RNA exonuclease 5

1

0

High-throughput

0.249

Low

88445

D3Z4Z0
Transcriptional adapter

1

0

High-throughput

0.249

Low

93237

E9PWB6
Mucin 5, subtypes A and C, tracheobronchial/gastric

1

0

High-throughput

0.249

Low

186316

O19442
Histocompatibility 2, M region locus 9

1

0

High-throughput

0.249

Low

192729

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.249

Low

291370

NID2
Nidogen-2

1

0

High-throughput

0.249

Low

594442

HXB9
Homeobox protein Hox-B9

1

0

High-throughput

0.249

Low

642901

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.249

Low

659545

SNAB
Beta-soluble NSF attachment protein

1

0

High-throughput

0.249

Low

886700

HPCL1
Hippocalcin-like protein 1

1

0

High-throughput

0.249

Low

886710

PRKDC
DNA-dependent protein kinase catalytic subunit

1

0

High-throughput

0.249

Low

886719

CDK12
Cyclin-dependent kinase 12

1

0

High-throughput

0.249

Low

886723

ESYT1
Extended synaptotagmin-1

1

0

High-throughput

0.249

Low

886724

PROM2
Prominin-2

1

0

High-throughput

0.249

Low

886726

GUC2C
Guanylyl cyclase C

1

0

High-throughput

0.249

Low

886727

Q3UX37
Pleckstrin homology domain containing, family G

1

0

High-throughput

0.249

Low

886730

TR150
Thyroid hormone receptor-associated protein 3

1

0

High-throughput

0.249

Low

886731

LIN54
Protein lin-54 homolog

1

0

High-throughput

0.249

Low

886733

NOL10
Nucleolar protein 10

1

0

High-throughput

0.249

Low

886746

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.249

Low

886747

EX3L4
Exocyst complex component 3-like protein 4

1

0

High-throughput

0.249

Low

886751

Q6IMH7
A disintegrin and metallopeptidase domain 6B

1

0

High-throughput

0.249

Low

886753

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.249

Low

886756

Q6P9L5
Nup205 protein

1

0

High-throughput

0.249

Low

886759

ATPMK
ATP synthase membrane subunit K, mitochondrial

1

0

High-throughput

0.249

Low

886764

ZSWM5
Zinc finger SWIM domain-containing protein 5

1

0

High-throughput

0.249

Low

886768

COQ4
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial

1

0

High-throughput

0.249

Low

886769

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.249

Low

886775

Q8BU90
Olfactomedin 5

1

0

High-throughput

0.249

Low

886777

Q8BUX1
BTB domain-containing protein

1

0

High-throughput

0.249

Low

886782

F161B
Protein FAM161B

1

0

High-throughput

0.249

Low

886783

TTC27
Tetratricopeptide repeat protein 27

1

0

High-throughput

0.249

Low

886788

Q8CEW7
Uncharacterized protein

1

0

High-throughput

0.249

Low

886789

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.249

Low

886793

SMDC1
SAYSvFN domain-containing protein 1

1

0

High-throughput

0.249

Low

886794

FRRS1
Ferric-chelate reductase 1

1

0

High-throughput

0.249

Low

886798

ANGL6
Angiopoietin-related protein 6

1

0

High-throughput

0.249

Low

886806

CSCL1
CSC1-like protein 1

1

0

High-throughput

0.249

Low

886817

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.249

Low

886821

Q9DAN0
IQ domain-containing protein M

1

0

High-throughput

0.249

Low

886823

CALY
Neuron-specific vesicular protein calcyon

1

0

High-throughput

0.249

Low

886839

CCR9
C-C chemokine receptor type 9

1

0

High-throughput

0.249

Low

886843

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024