Protein: SPAG6
Sperm-associated antigen 6 (Axoneme central apparatus protein) (Protein PF16 homolog)

Gene: SPAG6
Organism: Mus musculus
Interactions: 193
UniProt ID: Q9JLI7

Gene Ontology (top 5):
GO:0001669 - acrosomal vesicle
GO:0002177 - manchette
GO:0003351 - epithelial cilium movement involved in extracellular fluid movement
GO:0003356 - regulation of cilium beat frequency
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1160704

HERC4
Probable E3 ubiquitin-protein ligase HERC4

1

6

High-throughput

0.621

High

1186612

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

6

High-throughput

0.621

High

193528

CSN5
COP9 signalosome complex subunit 5

1

6

High-throughput

0.552

High

516956

DYLT2
Dynein light chain Tctex-type protein 2

1

0

High-throughput

0.529

High

1206925

ISK2
Serine protease inhibitor Kazal-type 2

1

0

High-throughput

0.529

High

1337533

SNAPN
SNARE-associated protein Snapin

1

0

High-throughput

0.529

High

1148451

PKP4
Plakophilin-4

1

0

High-throughput

0.519

High

1130104

SPG17
Sperm-associated antigen 17

1

0

Small-scale

0.484

High

88441

HFM1
Probable ATP-dependent DNA helicase HFM1

1

3

High-throughput

0.481

High

193105

NPC1
NPC intracellular cholesterol transporter 1

1

2

High-throughput

0.481

High

193225

STAG2
Cohesin subunit SA-2

1

1

High-throughput

0.481

High

640202

MOES
Moesin

1

3

High-throughput

0.481

High

760468

DYN1
Dynamin-1

1

1

High-throughput

0.481

High

814221

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

1

High-throughput

0.481

High

815159

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.481

High

819136

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

5

High-throughput

0.481

High

868088

STMN1
Stathmin

1

1

High-throughput

0.481

High

897023

ARP2
Actin-related protein 2

1

6

High-throughput

0.481

High

930503

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.481

High

946004

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.481

High

1112507

Q3UH16
Kinesin-like protein KIF1A

1

2

High-throughput

0.481

High

1142907

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.481

High

1145381

IFIT3
Interferon-induced protein with tetratricopeptide repeats 3

1

6

High-throughput

0.481

High

1154103

NIPBL
Nipped-B-like protein

1

6

High-throughput

0.481

High

1163213

RIGI
Antiviral innate immune response receptor RIG-I

1

4

High-throughput

0.481

High

1193588

DGKZ
Diacylglycerol kinase zeta

1

1

High-throughput

0.481

High

1206750

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

11

High-throughput

0.481

High

1207043

Q8BPC3
Uncharacterized protein

1

6

High-throughput

0.481

High

1207897

BBS4
Bardet-Biedl syndrome 4 protein homolog

1

6

High-throughput

0.481

High

1225092

FEZ1
Fasciculation and elongation protein zeta-1

1

1

High-throughput

0.481

High

1225264

SPG16
Sperm-associated antigen 16 protein

1

6

Small-scale

0.481

High

1247014

CADM1
Cell adhesion molecule 1

1

1

High-throughput

0.481

High

1257469

TTC8
Tetratricopeptide repeat protein 8

1

7

High-throughput

0.481

High

1257539

GPSM2
G-protein-signaling modulator 2

1

6

High-throughput

0.481

High

1257572

VPS4A
Vacuolar protein sorting-associated protein 4A

1

3

High-throughput

0.481

High

1337457

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

1

1

High-throughput

0.481

High

1337470

COPB
Coatomer subunit beta

1

2

High-throughput

0.481

High

1337527

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

5

High-throughput

0.481

High

1337528

CDC7
Cell division cycle 7-related protein kinase

1

7

High-throughput

0.481

High

1337530

IKBA
NF-kappa-B inhibitor alpha

1

6

High-throughput

0.481

High

1337535

SUCB1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

2

High-throughput

0.481

High

57092

MEIOC
Meiosis-specific coiled-coil domain-containing protein MEIOC

1

0

High-throughput

0.460

High

60175

GBP4
Guanylate-binding protein 4

1

0

High-throughput

0.460

High

70954

HSBPL
Heat shock factor-binding protein 1-like protein 1

1

0

High-throughput

0.460

High

88438

RBM24
RNA-binding protein 24

1

0

High-throughput

0.460

High

93296

IF140
Intraflagellar transport protein 140 homolog

1

0

High-throughput

0.460

High

437624

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.460

High

549314

GSTM2
Glutathione S-transferase Mu 2

1

0

High-throughput

0.460

High

589138

TYB4
Thymosin beta-4

1

0

High-throughput

0.460

High

783514

TKN1
Protachykinin-1

1

0

High-throughput

0.460

High

789695

LIFR
Leukemia inhibitory factor receptor

1

0

High-throughput

0.460

High

886900

IF5
Eukaryotic translation initiation factor 5

1

0

High-throughput

0.460

High

926378

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.460

High

1112730

NEPR1
Nuclear envelope phosphatase-regulatory subunit 1

1

0

High-throughput

0.460

High

1131450

PSME4
Proteasome activator complex subunit 4

1

0

High-throughput

0.460

High

1131536

MYBPP
MYCBP-associated protein

1

0

High-throughput

0.460

High

1141189

AKAP4
A-kinase anchor protein 4

1

0

High-throughput

0.460

High

1145393

DAZL
Deleted in azoospermia-like

1

0

High-throughput

0.460

High

1157929

SORCN
Sorcin

1

0

High-throughput

0.460

High

1194434

ARM12
Armadillo repeat-containing protein 12

1

0

High-throughput

0.460

High

1195003

CCD50
Coiled-coil domain-containing protein 50

1

0

High-throughput

0.460

High

1206486

CFA69
Cilia- and flagella-associated protein 69

1

0

High-throughput

0.460

High

1207280

KAT1
Kynurenine--oxoglutarate transaminase 1

1

0

High-throughput

0.460

High

1208067

SPEF2
Sperm flagellar protein 2

1

0

High-throughput

0.460

High

1208078

PGM2L
Glucose 1,6-bisphosphate synthase

1

0

High-throughput

0.460

High

1225229

DP13B
DCC-interacting protein 13-beta

1

0

High-throughput

0.460

High

1225242

BABA2
BRISC and BRCA1-A complex member 2

1

0

High-throughput

0.460

High

1257538

CE57L
Centrosomal protein CEP57L1

1

0

High-throughput

0.460

High

1257600

DRC2
Dynein regulatory complex subunit 2

1

0

High-throughput

0.460

High

1265311

FPPS
Farnesyl pyrophosphate synthase

1

0

High-throughput

0.460

High

1321797

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.460

High

1321854

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

0

High-throughput

0.460

High

1322050

VATE2
V-type proton ATPase subunit E 2

1

0

High-throughput

0.460

High

1322109

SNX5
Sorting nexin-5

1

0

High-throughput

0.460

High

1322127

Q9DAA5
Sperm acrosome associated 7B

1

0

High-throughput

0.460

High

1322194

RMD1
Regulator of microtubule dynamics protein 1

1

0

High-throughput

0.460

High

1337525

GUAD
Guanine deaminase

1

0

High-throughput

0.460

High

93745

E9QAE3
B-TFIID TATA-box binding protein associated factor 1

1

20

High-throughput

0.439

High

102300

G3UVU7
WD repeat domain 17

1

7

High-throughput

0.439

High

103586

ZBT11
Zinc finger and BTB domain-containing protein 11

1

5

High-throughput

0.439

High

193161

MDM4
Protein Mdm4

1

3

High-throughput

0.439

High

291842

ZFR
Zinc finger RNA-binding protein

1

4

High-throughput

0.439

High

485429

ZFP28
Zinc finger protein 28

1

5

High-throughput

0.439

High

661518

TBP
TATA-box-binding protein

1

2

High-throughput

0.439

High

878803

STMN2
Stathmin-2

1

1

High-throughput

0.439

High

926322

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.439

High

1012213

TIGD2
Tigger transposable element-derived protein 2

1

4

High-throughput

0.439

High

1012648

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

1

3

High-throughput

0.439

High

1112711

NOL8
Nucleolar protein 8

1

1

High-throughput

0.439

High

1113320

Q3UV11
Keratin 6B

1

1

High-throughput

0.439

High

1125414

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

4

High-throughput

0.439

High

1126607

CAGE1
Cancer-associated gene 1 protein homolog

1

3

High-throughput

0.439

High

1131516

LC7L3
Luc7-like protein 3

1

3

High-throughput

0.439

High

1141833

SLAP1
Src-like-adapter

1

2

High-throughput

0.439

High

1142556

TCPW
T-complex protein 1 subunit zeta-2

1

3

High-throughput

0.439

High

1142609

DAF1
Complement decay-accelerating factor, GPI-anchored

1

1

High-throughput

0.439

High

1144368

TP4A1
Protein tyrosine phosphatase type IVA 1

1

1

High-throughput

0.439

High

1194389

HOMEZ
Homeobox and leucine zipper protein Homez

1

3

High-throughput

0.439

High

1206847

SMG1
Serine/threonine-protein kinase SMG1

1

7

High-throughput

0.439

High

1206859

CDKL3
Cyclin-dependent kinase-like 3

1

4

High-throughput

0.439

High

1207273

NUP54
Nuclear pore complex protein Nup54

1

6

High-throughput

0.439

High

1207975

BHE22
Class E basic helix-loop-helix protein 22

1

1

High-throughput

0.439

High

1207989

BTBD9
BTB/POZ domain-containing protein 9

1

9

High-throughput

0.439

High

1208087

MIC60
MICOS complex subunit Mic60

1

2

High-throughput

0.439

High

1208434

TCRG1
Transcription elongation regulator 1

1

17

High-throughput

0.439

High

1246850

PSPC1
Paraspeckle component 1

1

2

High-throughput

0.439

High

1265253

PRP6
Pre-mRNA-processing factor 6

1

7

High-throughput

0.439

High

1265763

TRI59
Tripartite motif-containing protein 59

1

6

High-throughput

0.439

High

1307788

PLST
Plastin-3

1

2

High-throughput

0.439

High

1321720

PCYOX
Prenylcysteine oxidase 1

1

1

High-throughput

0.439

High

1321855

NOPC1
NOP protein chaperone 1

1

3

High-throughput

0.439

High

1321953

PEX13
Peroxisomal membrane protein PEX13

1

1

High-throughput

0.439

High

1321997

ANKE1
Ankyrin repeat and EF-hand domain-containing protein 1

1

1

High-throughput

0.439

High

1322038

Q9D496
Coiled-coil domain containing 121

1

2

High-throughput

0.439

High

1337524

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

1

1

High-throughput

0.439

High

1337526

CUL1
Cullin-1

1

16

High-throughput

0.439

High

1337532

AEBP2
Zinc finger protein AEBP2

1

9

High-throughput

0.439

High

1337534

BAZ1B
Tyrosine-protein kinase BAZ1B

1

20

High-throughput

0.439

High

57199

D19L4
Probable C-mannosyltransferase DPY19L4

1

0

High-throughput

0.251

Low

57485

FA209
Protein FAM209

1

0

High-throughput

0.251

Low

70556

B2RQ99
6820408C15Rik protein

1

0

High-throughput

0.251

Low

88303

RFX8
DNA-binding protein RFX8

1

0

High-throughput

0.251

Low

88428

CIP1
E3 ubiquitin-protein ligase CCNB1IP1

1

0

High-throughput

0.251

Low

93289

E9PXD1
Protease, serine 51

1

0

High-throughput

0.251

Low

111144

I6L970
Lipid droplet-regulating VLDL assembly factor AUP1

1

0

High-throughput

0.251

Low

192805

C1D
Nuclear nucleic acid-binding protein C1D

1

0

High-throughput

0.251

Low

222930

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

1

0

High-throughput

0.251

Low

223260

LDB2
LIM domain-binding protein 2

1

0

High-throughput

0.251

Low

587111

MGP
Matrix Gla protein

1

0

High-throughput

0.251

Low

680343

DPEP1
Dipeptidase 1

1

0

High-throughput

0.251

Low

706861

PRI2
DNA primase large subunit

1

0

High-throughput

0.251

Low

796686

SDC2
Syndecan-2

1

0

High-throughput

0.251

Low

841374

BTG3
Protein BTG3

1

0

High-throughput

0.251

Low

849081

GPC4
Glypican-4

1

0

High-throughput

0.251

Low

877598

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.251

Low

885215

RT06
Small ribosomal subunit protein bS6m

1

0

High-throughput

0.251

Low

886451

CSRN3
Cysteine/serine-rich nuclear protein 3

1

0

High-throughput

0.251

Low

902859

UFM1
Ubiquitin-fold modifier 1

1

0

High-throughput

0.251

Low

946721

DEFB2
Beta-defensin 2

1

0

High-throughput

0.251

Low

956914

GFRA1
GDNF family receptor alpha-1

1

0

High-throughput

0.251

Low

1103600

MSTO1
Protein misato homolog 1

1

0

High-throughput

0.251

Low

1112087

CH048
Uncharacterized protein C8orf48 homolog

1

0

High-throughput

0.251

Low

1112474

TNKS2
Poly [ADP-ribose] polymerase tankyrase-2

1

0

High-throughput

0.251

Low

1112484

RSH3A
Radial spoke head protein 3 homolog A

1

0

High-throughput

0.251

Low

1112749

CE034
Uncharacterized protein C5orf34 homolog

1

0

High-throughput

0.251

Low

1113340

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

0

High-throughput

0.251

Low

1114428

SNX25
Sorting nexin-25

1

0

High-throughput

0.251

Low

1142581

HCDH
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

1

0

High-throughput

0.251

Low

1142927

GPAT1
Glycerol-3-phosphate acyltransferase 1, mitochondrial

1

0

High-throughput

0.251

Low

1143087

RT31
Small ribosomal subunit protein mS31

1

0

High-throughput

0.251

Low

1145035

ASPG
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase

1

0

High-throughput

0.251

Low

1149761

SIDT1
SID1 transmembrane family member 1

1

0

High-throughput

0.251

Low

1157649

K1328
Protein hinderin

1

0

High-throughput

0.251

Low

1193580

INT2
Integrator complex subunit 2

1

0

High-throughput

0.251

Low

1194404

LYRIC
Protein LYRIC

1

0

High-throughput

0.251

Low

1194479

DDHD1
Phospholipase DDHD1

1

0

High-throughput

0.251

Low

1206452

MID51
Mitochondrial dynamics protein MID51

1

0

High-throughput

0.251

Low

1206458

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

High-throughput

0.251

Low

1206578

CGBP1
CGG triplet repeat-binding protein 1

1

0

High-throughput

0.251

Low

1207225

PHF23
PHD finger protein 23

1

0

High-throughput

0.251

Low

1207267

Q8BTS0
Probable ATP-dependent RNA helicase DDX5

1

0

High-throughput

0.251

Low

1207495

NMUR2
Neuromedin-U receptor 2

1

0

High-throughput

0.251

Low

1207946

U119B
Protein unc-119 homolog B

1

0

High-throughput

0.251

Low

1208115

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.251

Low

1208116

DCNL4
DCN1-like protein 4

1

0

High-throughput

0.251

Low

1208264

NUP88
Nuclear pore complex protein Nup88

1

0

High-throughput

0.251

Low

1208463

CS2IP
Casein kinase II subunit alpha'-interacting protein

1

0

High-throughput

0.251

Low

1225103

T11L2
T-complex protein 11-like protein 2

1

0

High-throughput

0.251

Low

1225146

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.251

Low

1225157

INT10
Integrator complex subunit 10

1

0

High-throughput

0.251

Low

1225177

BROX
BRO1 domain-containing protein BROX

1

0

High-throughput

0.251

Low

1225246

I2BPL
Probable E3 ubiquitin-protein ligase IRF2BPL

1

0

High-throughput

0.251

Low

1246860

CLMP
CXADR-like membrane protein

1

0

High-throughput

0.251

Low

1265325

REV1
DNA repair protein REV1

1

0

High-throughput

0.251

Low

1265726

TFIP8
Tumor necrosis factor alpha-induced protein 8

1

0

High-throughput

0.251

Low

1267829

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.251

Low

1307771

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

0

High-throughput

0.251

Low

1307854

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.251

Low

1321858

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

0

High-throughput

0.251

Low

1321894

PSF1
DNA replication complex GINS protein PSF1

1

0

High-throughput

0.251

Low

1321921

Q9D031
Ras suppressor protein 1

1

0

High-throughput

0.251

Low

1321947

RT30
Large ribosomal subunit protein mL65

1

0

High-throughput

0.251

Low

1321965

MESH1
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1

1

0

High-throughput

0.251

Low

1321999

COA3
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial

1

0

High-throughput

0.251

Low

1322092

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

1

0

High-throughput

0.251

Low

1322111

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

0

High-throughput

0.251

Low

1322124

F217A
Protein FAM217A

1

0

High-throughput

0.251

Low

1337489

SPP2A
Signal peptide peptidase-like 2A

1

0

High-throughput

0.251

Low

1337522

ARPC3
Actin-related protein 2/3 complex subunit 3

1

0

High-throughput

0.251

Low

1337523

NUFP1
FMR1-interacting protein NUFIP1

1

0

High-throughput

0.251

Low

1337529

CPXM1
Probable carboxypeptidase X1

1

0

High-throughput

0.251

Low

1337531

RED
Protein Red

1

0

High-throughput

0.251

Low

1337536

UBL3
Ubiquitin-like protein 3

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024