Protein: THOC1
THO complex subunit 1 (Tho1) (Nuclear matrix protein p84) (p84N5) (hTREX84)

Gene: THOC1
Organism: Homo sapiens
Interactions: 180
UniProt ID: Q96FV9

Gene Ontology (top 5):
GO:0000346 - transcription export complex
GO:0000347 - THO complex
GO:0000445 - THO complex part of transcription export complex
GO:0003677 - DNA binding
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1045271

THOC5
THO complex subunit 5 homolog

9

1

Small-scale

0.973

High

1246348

THOC2
THO complex subunit 2

8

3

Small-scale

0.966

High

1151838

THOC7
THO complex subunit 7 homolog

5

1

Small-scale

0.925

High

1046131

DX39B
Spliceosome RNA helicase DDX39B

10

3

Small-scale

0.754

High

1201126

THOC4
THO complex subunit 4

5

2

Small-scale

0.716

High

1202878

THOC6
THO complex subunit 6 homolog

5

3

Small-scale

0.716

High

1291496

THOC3
THO complex subunit 3

4

2

High-throughput

0.699

High

948900

SARNP
SAP domain-containing ribonucleoprotein

3

1

High-throughput

0.675

High

1285996

MOAP1
Modulator of apoptosis 1

4

0

High-throughput

0.668

High

1290361

RBM33
RNA-binding protein 33

3

0

High-throughput

0.638

High

117199

DX39A
ATP-dependent RNA helicase DDX39A

2

3

High-throughput

0.628

High

1291495

THOC1
THO complex subunit 1

1

0

High-throughput

0.622

High

1120428

NCBP3
Nuclear cap-binding protein subunit 3

3

0

High-throughput

0.616

High

856776

RM12
Large ribosomal subunit protein bL12m

2

0

High-throughput

0.602

High

1035976

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.586

High

1291538

CHTOP
Chromatin target of PRMT1 protein

2

0

Small-scale

0.585

High

256562

ZC11A
Zinc finger CCCH domain-containing protein 11A

2

0

High-throughput

0.585

High

268820

SF3B1
Splicing factor 3B subunit 1

2

0

Small-scale

0.585

High

1238416

CS047
Uncharacterized protein C19orf47

2

0

High-throughput

0.585

High

130093

EXOC5
Exocyst complex component 5

2

0

High-throughput

0.580

High

180567

MAGB4
Melanoma-associated antigen B4

2

0

High-throughput

0.580

High

266407

TAD2A
Transcriptional adapter 2-alpha

2

0

High-throughput

0.580

High

536985

TRI27
Zinc finger protein RFP

2

0

High-throughput

0.580

High

641520

PAX6
Paired box protein Pax-6

2

0

High-throughput

0.580

High

942544

CTG1B
Cancer/testis antigen 1

2

0

High-throughput

0.580

High

981686

REL
Proto-oncogene c-Rel

2

0

High-throughput

0.580

High

1161648

GASP3
G protein-coupled receptor associated sorting protein 3

2

0

High-throughput

0.580

High

1291506

PP12C
Protein phosphatase 1 regulatory subunit 12C

2

0

High-throughput

0.580

High

1236676

USBP1
Harmonin-binding protein USHBP1

1

1

High-throughput

0.573

High

1291505

TRI54
Tripartite motif-containing protein 54

1

2

High-throughput

0.573

High

553423

RFA2
Replication protein A 32 kDa subunit

2

0

High-throughput

0.559

High

651940

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

High-throughput

0.559

High

721143

RFA3
Replication protein A 14 kDa subunit

2

0

High-throughput

0.559

High

1162370

ZC3HE
Zinc finger CCCH domain-containing protein 14

2

0

High-throughput

0.559

High

1039771

SNW1
SNW domain-containing protein 1

2

0

High-throughput

0.552

High

1291531

RABX5
Rab5 GDP/GTP exchange factor

1

0

High-throughput

0.549

High

1159747

RHGBA
Rho GTPase-activating protein 11A

2

0

High-throughput

0.547

High

808222

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

Small-scale

0.537

High

256320

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

1

High-throughput

0.536

High

508657

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.536

High

843842

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.536

High

877339

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

1

High-throughput

0.536

High

941813

RBM6
RNA-binding protein 6

1

1

High-throughput

0.536

High

989052

FMR1
Fragile X messenger ribonucleoprotein 1

1

1

High-throughput

0.536

High

994286

DHX9
ATP-dependent RNA helicase A

1

1

High-throughput

0.536

High

1132723

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

1

High-throughput

0.536

High

1291504

PDIP3
Polymerase delta-interacting protein 3

1

2

High-throughput

0.536

High

1291511

SFR19
Splicing factor, arginine/serine-rich 19

1

1

High-throughput

0.536

High

1291513

SP110
Sp110 nuclear body protein

1

1

High-throughput

0.536

High

1291515

DDX21
Nucleolar RNA helicase 2

1

1

High-throughput

0.536

High

1291520

BCLF1
Bcl-2-associated transcription factor 1

1

2

High-throughput

0.536

High

1291524

RBM27
RNA-binding protein 27

1

1

High-throughput

0.536

High

1291536

TR150
Thyroid hormone receptor-associated protein 3

1

2

High-throughput

0.536

High

1162263

Q6PJH3
A kinase

1

1

High-throughput

0.515

High

58242

SYTC2
Threonine--tRNA ligase 2, cytoplasmic

1

0

High-throughput

0.513

High

124043

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.513

High

216959

KIF1C
Kinesin-like protein KIF1C

1

0

High-throughput

0.513

High

230414

ZC3H1
Zinc finger C3H1 domain-containing protein

1

0

High-throughput

0.513

High

259373

DUS11
RNA/RNP complex-1-interacting phosphatase

1

0

High-throughput

0.513

High

328921

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.513

High

331064

PAK4
Serine/threonine-protein kinase PAK 4

1

0

High-throughput

0.513

High

414027

GELS
Gelsolin

1

0

High-throughput

0.513

High

440668

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.513

High

446741

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.513

High

448776

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

539100

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.513

High

739232

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

757712

IF4A3
Eukaryotic initiation factor 4A-III

1

0

High-throughput

0.513

High

801303

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

911930

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.513

High

957112

TSG6
Tumor necrosis factor-inducible gene 6 protein

1

0

High-throughput

0.513

High

996825

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1037868

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

0

High-throughput

0.513

High

1054505

RBM39
RNA-binding protein 39

1

0

High-throughput

0.513

High

1074203

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

1084568

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.513

High

1172921

CCD9B
Coiled-coil domain-containing protein 9B

1

0

High-throughput

0.513

High

1221429

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

0

High-throughput

0.513

High

1242565

RB15B
Putative RNA-binding protein 15B

1

0

High-throughput

0.513

High

1264544

ATG4A
Cysteine protease ATG4A

1

0

High-throughput

0.513

High

1291497

PWP2A
PWWP domain-containing protein 2A

1

0

High-throughput

0.513

High

1291498

UIF
UAP56-interacting factor

1

0

High-throughput

0.513

High

1291500

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.513

High

1291510

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.513

High

1291512

CAAP1
Caspase activity and apoptosis inhibitor 1

1

0

High-throughput

0.513

High

1291521

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

1291523

BCCIP
BRCA2 and CDKN1A-interacting protein

1

0

High-throughput

0.513

High

1291526

IKBL1
NF-kappa-B inhibitor-like protein 1

1

0

High-throughput

0.513

High

1291534

RTRAF
RNA transcription, translation and transport factor protein

1

0

High-throughput

0.513

High

1291537

RTCB
RNA-splicing ligase RtcB homolog

1

0

High-throughput

0.513

High

1024938

RED
Protein Red

1

1

High-throughput

0.508

High

1055448

DHX8
ATP-dependent RNA helicase DHX8

1

1

High-throughput

0.508

High

414355

RB
Retinoblastoma-associated protein

1

0

Small-scale

0.504

High

1291517

RBM22
Pre-mRNA-splicing factor RBM22

1

0

High-throughput

0.493

High

1034368

SF3B2
Splicing factor 3B subunit 2

1

0

High-throughput

0.486

High

1174480

F10C1
Protein FRA10AC1

1

0

High-throughput

0.486

High

1291502

MEP50
Methylosome protein WDR77

1

0

High-throughput

0.486

High

1291530

S30BP
SAP30-binding protein

1

0

High-throughput

0.486

High

1291501

AKAP9
A-kinase anchor protein 9

1

2

High-throughput

0.481

High

282713

RNF8
E3 ubiquitin-protein ligase RNF8

1

1

High-throughput

0.479

High

322992

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

347574

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

379717

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

531945

PDIA4
Protein disulfide-isomerase A4

1

1

High-throughput

0.479

High

569957

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

726981

FUS
RNA-binding protein FUS

1

2

High-throughput

0.479

High

749769

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

875710

MFAP1
Microfibrillar-associated protein 1

1

1

Small-scale

0.479

High

925102

TRA2B
Transformer-2 protein homolog beta

1

2

High-throughput

0.479

High

959597

VIGLN
Vigilin

1

1

High-throughput

0.479

High

992880

SRSF1
Serine/arginine-rich splicing factor 1

1

1

High-throughput

0.479

High

1028596

SRSF9
Serine/arginine-rich splicing factor 9

1

1

High-throughput

0.479

High

1135212

RBM26
RNA-binding protein 26

1

1

High-throughput

0.479

High

1171209

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

1191707

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

1

High-throughput

0.479

High

1201595

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.479

High

1271161

RBP56
TATA-binding protein-associated factor 2N

1

1

High-throughput

0.479

High

1291499

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.479

High

1291539

RBM8A
RNA-binding protein 8A

1

1

High-throughput

0.479

High

210197

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.460

High

300230

PRP6
Pre-mRNA-processing factor 6

1

0

High-throughput

0.460

High

1063752

EXOS7
Exosome complex component RRP42

1

0

High-throughput

0.460

High

1288146

ESS2
Splicing factor ESS-2 homolog

1

0

High-throughput

0.460

High

1291525

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.460

High

129818

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.458

High

163633

BTAF1
TATA-binding protein-associated factor 172

1

0

High-throughput

0.458

High

179772

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

233583

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

244777

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

255984

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

270440

KS6A5
Ribosomal protein S6 kinase alpha-5

1

0

High-throughput

0.458

High

374682

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

430299

PROF1
Profilin-1

1

0

Small-scale

0.458

High

558537

GCFC2
Intron Large complex component GCFC2

1

0

High-throughput

0.458

High

579481

DNLI1
DNA ligase 1

1

0

High-throughput

0.458

High

801930

RECQ1
ATP-dependent DNA helicase Q1

1

0

High-throughput

0.458

High

882968

RBM11
Splicing regulator RBM11

1

0

High-throughput

0.458

High

900057

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.458

High

917734

H4
Histone H4

1

0

High-throughput

0.458

High

968201

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.458

High

998150

NCBP1
Nuclear cap-binding protein subunit 1

1

0

Small-scale

0.458

High

1059594

MEF2D
Myocyte-specific enhancer factor 2D

1

0

High-throughput

0.458

High

1081359

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1191137

I2BP2
Interferon regulatory factor 2-binding protein 2

1

0

High-throughput

0.458

High

1221638

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1230916

CMTR1
Cap-specific mRNA

1

0

High-throughput

0.458

High

1269346

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1283824

FUBP1
Far upstream element-binding protein 1

1

0

High-throughput

0.458

High

1286443

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1291503

NADAP
Kanadaptin

1

0

High-throughput

0.458

High

1291507

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1291509

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1291514

ANLN
Anillin

1

0

High-throughput

0.458

High

1291518

AATF
Protein AATF

1

0

High-throughput

0.458

High

1291519

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1291522

LUZP4
Leucine zipper protein 4

1

0

Small-scale

0.458

High

1291529

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1291532

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.458

High

1291533

TRI33
E3 ubiquitin-protein ligase TRIM33

1

0

High-throughput

0.458

High

92364

E9PB61
Aly/REF export factor

1

2

High-throughput

0.445

High

108885

H0YHG0
DnaJ homolog subfamily C member 14

1

1

High-throughput

0.445

High

1291527

NXF1
Nuclear RNA export factor 1

1

1

Small-scale

0.445

High

772110

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.438

High

1146722

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

1291535

RT17
Small ribosomal subunit protein uS17m

1

1

High-throughput

0.437

High

1059342

CASP8
Caspase-8

1

0

High-throughput

0.426

High

1124587

ODFP2
Outer dense fiber protein 2

1

0

High-throughput

0.426

High

1130437

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

111058

I3L0E3
HCG1984214, isoform CRA_a

1

1

High-throughput

0.407

High

329886

AGR2
Anterior gradient protein 2 homolog

2

0

High-throughput

0.316

High

1291508

ZMY12
Zinc finger MYND domain-containing protein 12

2

0

High-throughput

0.316

High

195738

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

0

High-throughput

0.279

Low

1291528

B4GT7
Beta-1,4-galactosyltransferase 7

1

0

High-throughput

0.279

Low

825725

MTR1B
Melatonin receptor type 1B

1

0

High-throughput

0.265

Low

149163

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

1153667

ANO7
Anoctamin-7

1

0

Small-scale

0.249

Low

1291516

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.238

Low

200653

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.232

Low

1241571

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024