Protein: MFF
Mitochondrial fission factor

Gene: MFF
Organism: Homo sapiens
Interactions: 181
UniProt ID: Q9GZY8

Gene Ontology (top 5):
GO:0000266 - mitochondrial fission
GO:0001836 - release of cytochrome c from mitochondria
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005777 - peroxisome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

128636

DNM1L
Dynamin-1-like protein

4

2

Small-scale

0.683

High

1326893

MFF
Mitochondrial fission factor

3

0

Small-scale

0.630

High

676613

CTR1
High affinity cationic amino acid transporter 1

2

2

High-throughput

0.606

High

1079696

ADIPO
Adiponectin

2

1

High-throughput

0.606

High

1191114

SPT19
Spermatogenesis-associated protein 19, mitochondrial

2

0

High-throughput

0.602

High

70838

SMIM1
Small integral membrane protein 1

2

0

High-throughput

0.580

High

178764

STX7
Syntaxin-7

2

0

High-throughput

0.580

High

196866

CYB5B
Cytochrome b5 type B

2

0

High-throughput

0.580

High

364425

TFR1
Transferrin receptor protein 1

2

0

High-throughput

0.580

High

644426

PPLA
Cardiac phospholamban

2

0

High-throughput

0.580

High

1136883

TSPO2
Translocator protein 2

2

0

High-throughput

0.580

High

1202375

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.580

High

1281114

FATE1
Fetal and adult testis-expressed transcript protein

2

0

High-throughput

0.580

High

1296511

F210B
Protein FAM210B, mitochondrial

2

0

High-throughput

0.580

High

1326901

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

2

0

High-throughput

0.580

High

1326911

TM14C
Transmembrane protein 14C

2

0

High-throughput

0.580

High

1326916

T3JAM
TRAF3-interacting JNK-activating modulator

2

0

High-throughput

0.580

High

1326919

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.580

High

998437

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

2

1

High-throughput

0.574

High

1289610

CC126
Coiled-coil domain-containing protein 126

2

1

High-throughput

0.574

High

1281377

FBXW7
F-box/WD repeat-containing protein 7

2

0

Small-scale

0.559

High

1283934

S2546
Mitochondrial outer membrane protein SLC25A46

2

0

Small-scale

0.559

High

1326909

MARH5
E3 ubiquitin-protein ligase MARCHF5

2

0

Small-scale

0.559

High

1326923

SAM50
Sorting and assembly machinery component 50 homolog

2

0

Small-scale

0.559

High

169604

BET1
BET1 homolog

2

1

High-throughput

0.553

High

237759

TSN2
Tetraspanin-2

2

2

High-throughput

0.553

High

263351

SC22B
Vesicle-trafficking protein SEC22b

2

1

High-throughput

0.553

High

276339

UPK1B
Uroplakin-1b

2

2

High-throughput

0.553

High

1255419

GP152
Probable G-protein coupled receptor 152

2

1

High-throughput

0.553

High

372941

OPSB
Short-wave-sensitive opsin 1

2

1

High-throughput

0.553

High

673343

MIP
Lens fiber major intrinsic protein

2

1

High-throughput

0.553

High

1037716

AQP6
Aquaporin-6

2

1

High-throughput

0.553

High

1199570

TSN33
Tetraspanin-33

2

2

High-throughput

0.553

High

1206271

C1QL4
Complement C1q-like protein 4

2

1

High-throughput

0.553

High

1252600

S7A14
Solute carrier family 7 member 14

2

2

High-throughput

0.553

High

1266032

AQP3
Aquaporin-3

2

1

High-throughput

0.553

High

1294707

SC22A
Vesicle-trafficking protein SEC22a

2

1

High-throughput

0.553

High

1326912

LPAR3
Lysophosphatidic acid receptor 3

2

1

High-throughput

0.553

High

1326914

LAT2
Large neutral amino acids transporter small subunit 2

2

2

High-throughput

0.553

High

1326915

STX8
Syntaxin-8

2

1

High-throughput

0.553

High

370395

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

1024758

TRAF3
TNF receptor-associated factor 3

1

0

Small-scale

0.537

High

489457

BCL2
Apoptosis regulator Bcl-2

1

1

High-throughput

0.536

High

825739

MTR1B
Melatonin receptor type 1B

1

1

High-throughput

0.494

High

201105

AQP9
Aquaporin-9

1

3

High-throughput

0.489

High

927504

1433Z
14-3-3 protein zeta/delta

1

1

High-throughput

0.489

High

1316197

DUS16
Dual specificity protein phosphatase 16

1

1

High-throughput

0.489

High

476341

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

120627

RHOD
Rho-related GTP-binding protein RhoD

1

7

High-throughput

0.479

High

545602

RAC2
Ras-related C3 botulinum toxin substrate 2

1

6

High-throughput

0.479

High

647261

1433T
14-3-3 protein theta

1

1

Small-scale

0.479

High

894402

CDC42
Cell division control protein 42 homolog

1

6

High-throughput

0.479

High

1220650

MIRO2
Mitochondrial Rho GTPase 2

1

8

High-throughput

0.479

High

1326910

MTCH1
Mitochondrial carrier homolog 1

1

1

High-throughput

0.479

High

1326924

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.479

High

61072

A5PKU2
TUSC5 protein

1

1

High-throughput

0.470

High

1151229

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

1159717

Q6P4D7
TM6SF1 protein

1

1

High-throughput

0.470

High

672995

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

0

High-throughput

0.460

High

118440

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.458

High

122989

MEN1
Menin

1

0

High-throughput

0.458

High

127048

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

157652

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.458

High

204047

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.458

High

264625

MTX2
Metaxin-2

1

0

High-throughput

0.458

High

325380

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.458

High

573894

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

845229

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.458

High

881676

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

1036885

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1053173

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.458

High

1072819

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.458

High

1085501

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.458

High

1190084

MAVS
Mitochondrial antiviral-signaling protein

1

0

High-throughput

0.458

High

1201903

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.458

High

1268909

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1294346

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.458

High

1303154

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

1326899

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1326902

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.458

High

1326906

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1326921

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

1326922

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.458

High

838261

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

1220536

TARG1
Trafficking regulator of GLUT4 1

1

1

High-throughput

0.439

High

1318452

TM6S1
Transmembrane 6 superfamily member 1

1

1

High-throughput

0.439

High

436494

RHOC
Rho-related GTP-binding protein RhoC

1

6

High-throughput

0.437

High

852610

RND2
Rho-related GTP-binding protein RhoN

1

7

High-throughput

0.437

High

892582

RAC3
Ras-related C3 botulinum toxin substrate 3

1

6

High-throughput

0.437

High

900875

RHOA
Transforming protein RhoA

1

7

High-throughput

0.437

High

925596

RAC1
Ras-related C3 botulinum toxin substrate 1

1

6

High-throughput

0.437

High

951313

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.437

High

1076745

RHOH
Rho-related GTP-binding protein RhoH

1

7

High-throughput

0.437

High

1326900

DUS22
Dual specificity protein phosphatase 22

1

1

High-throughput

0.437

High

58328

TM218
Transmembrane protein 218

2

0

High-throughput

0.316

High

151629

GOSR2
Golgi SNAP receptor complex member 2

2

0

High-throughput

0.316

High

153382

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

2

0

High-throughput

0.316

High

207490

LAT
Linker for activation of T-cells family member 1

2

0

High-throughput

0.316

High

261718

VAMP4
Vesicle-associated membrane protein 4

2

0

High-throughput

0.316

High

264465

MSPD3
Motile sperm domain-containing protein 3

2

0

High-throughput

0.316

High

274880

RHBL1
Rhomboid-related protein 1

2

0

High-throughput

0.316

High

305621

ZFPL1
Zinc finger protein-like 1

2

0

High-throughput

0.316

High

311113

MPZL1
Myelin protein zero-like protein 1

2

0

High-throughput

0.316

High

313604

CNIH1
Protein cornichon homolog 1

2

0

High-throughput

0.316

High

396415

APOD
Apolipoprotein D

2

0

High-throughput

0.316

High

434853

CXB1
Gap junction beta-1 protein

2

0

High-throughput

0.316

High

516138

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.316

High

623670

IBP5
Insulin-like growth factor-binding protein 5

2

0

High-throughput

0.316

High

666830

CO4A5

2

0

High-throughput

0.316

High

677622

NEUT
Neurotensin/neuromedin N [Cleaved into: Large neuromedin N

2

0

High-throughput

0.316

High

723101

OPRM
Mu-type opioid receptor

2

0

High-throughput

0.316

High

888303

MYPR
Myelin proteolipid protein

2

0

High-throughput

0.316

High

943621

S35B1
Solute carrier family 35 member B1

2

0

High-throughput

0.316

High

1074001

SC23A
Protein transport protein Sec23A

2

0

High-throughput

0.316

High

1083256

VACHT
Vesicular acetylcholine transporter

2

0

High-throughput

0.316

High

1109950

SHSL1
Protein shisa-like-1

2

0

High-throughput

0.316

High

1117650

CTXN3
Cortexin-3

2

0

High-throughput

0.316

High

1121588

UNC50
Protein unc-50 homolog

2

0

High-throughput

0.316

High

1124501

SGMR2
Sigma intracellular receptor 2

2

0

High-throughput

0.316

High

1124708

TM128
Transmembrane protein 128

2

0

High-throughput

0.316

High

1125122

TTMP
TPA-induced transmembrane protein

2

0

High-throughput

0.316

High

1128710

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1130918

TM201
Transmembrane protein 201

2

0

High-throughput

0.316

High

1139368

ULBP6
UL16-binding protein 6

2

0

High-throughput

0.316

High

1148565

TMM42
Transmembrane protein 42

2

0

High-throughput

0.316

High

1159621

NPAL3
NIPA-like protein 3

2

0

High-throughput

0.316

High

1161202

TMM88
Transmembrane protein 88

2

0

High-throughput

0.316

High

1202963

ANR46
Ankyrin repeat domain-containing protein 46

2

0

High-throughput

0.316

High

1221198

NRM
Nurim

2

0

High-throughput

0.316

High

1229959

CEND
Cell cycle exit and neuronal differentiation protein 1

2

0

High-throughput

0.316

High

1233947

EMC5
ER membrane protein complex subunit 5

2

0

High-throughput

0.316

High

1234925

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.316

High

1235414

TR1L1
Translocating chain-associated membrane protein 1-like 1

2

0

High-throughput

0.316

High

1235502

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.316

High

1235915

CLD19
Claudin-19

2

0

High-throughput

0.316

High

1238012

NRAC
Nutritionally-regulated adipose and cardiac enriched protein homolog

2

0

High-throughput

0.316

High

1239672

T229B
Transmembrane protein 229B

2

0

High-throughput

0.316

High

1244986

FDSCP
Follicular dendritic cell secreted peptide

2

0

High-throughput

0.316

High

1251280

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

0

High-throughput

0.316

High

1252929

TM254
Transmembrane protein 254

2

0

High-throughput

0.316

High

1266287

FAM3C
Protein FAM3C

2

0

High-throughput

0.316

High

1288904

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

0

High-throughput

0.316

High

1295721

S41A2
Solute carrier family 41 member 2

2

0

High-throughput

0.316

High

1300141

TM237
Transmembrane protein 237

2

0

High-throughput

0.316

High

1303506

VATO
V-type proton ATPase 21 kDa proteolipid subunit c''

2

0

High-throughput

0.316

High

1309343

CYBC1
Cytochrome b-245 chaperone 1

2

0

High-throughput

0.316

High

1309566

APOL2
Apolipoprotein L2

2

0

High-throughput

0.316

High

1316109

SC11C
Signal peptidase complex catalytic subunit SEC11C

2

0

High-throughput

0.316

High

1326894

FXYD6
FXYD domain-containing ion transport regulator 6

2

0

High-throughput

0.316

High

1326895

UN93B
Protein unc-93 homolog B1

2

0

High-throughput

0.316

High

1326897

TMM60
Transmembrane protein 60

2

0

High-throughput

0.316

High

1326898

PLK3
Serine/threonine-protein kinase PLK3

2

0

High-throughput

0.316

High

1326903

GKN1
Gastrokine-1

2

0

High-throughput

0.316

High

1326904

SAC1
Phosphatidylinositol-3-phosphatase SAC1

2

0

High-throughput

0.316

High

1326905

TM140
Transmembrane protein 140

2

0

High-throughput

0.316

High

1326907

AIG1
Androgen-induced gene 1 protein

2

0

High-throughput

0.316

High

1326917

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.316

High

1326920

PLLP
Plasmolipin

2

0

High-throughput

0.316

High

1326925

TX264
Testis-expressed protein 264

2

0

High-throughput

0.316

High

1317612

ACTBM
Putative beta-actin-like protein 3

2

0

High-throughput

0.288

High

63609

ASB14
Ankyrin repeat and SOCS box protein 14

1

0

High-throughput

0.279

Low

207271

TNF14
Tumor necrosis factor ligand superfamily member 14

1

0

High-throughput

0.279

Low

324018

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

1287374

OPTN
Optineurin

1

0

High-throughput

0.269

Low

483871

DWORF
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

1

0

High-throughput

0.268

Low

1301959

SERC2
Serine incorporator 2

1

0

High-throughput

0.251

Low

1326896

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.251

Low

131079

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.249

Low

134489

PODXL
Podocalyxin

1

0

Small-scale

0.249

Low

553660

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

652193

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

721392

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1171629

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1237783

ARL10
ADP-ribosylation factor-like protein 10

1

0

High-throughput

0.249

Low

1296901

SNX27
Sorting nexin-27

1

0

High-throughput

0.249

Low

1326908

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low

1326913

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

217945

PRKY
Putative serine/threonine-protein kinase PRKY

1

0

High-throughput

0.232

Low

240180

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low

1326918

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024