Protein: Q86WV8
TSC complex subunit 1 (Tuberous sclerosis 1)

Gene: Q86WV8, TSC1
Organism: Homo sapiens
Interactions: 126
UniProt ID: Q86WV8

Gene Ontology (top 5):
GO:0008285 - negative regulation of cell population proliferation
GO:0032007 - negative regulation of TOR signaling
GO:0033596 - TSC1-TSC2 complex
GO:0051726 - regulation of cell cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1203617

MYLIP
E3 ubiquitin-protein ligase MYLIP

2

7

High-throughput

0.558

High

1203629

SPAG8
Sperm-associated antigen 8

2

1

High-throughput

0.558

High

157948

KLF11
Krueppel-like factor 11

1

2

High-throughput

0.515

High

724249

MSX2
Homeobox protein MSX-2

1

0

High-throughput

0.493

High

1083801

BAK
Bcl-2 homologous antagonist/killer

1

0

High-throughput

0.493

High

60605

VP37C
Vacuolar protein sorting-associated protein 37C

1

2

High-throughput

0.470

High

67979

VGLL3
Transcription cofactor vestigial-like protein 3

1

1

High-throughput

0.470

High

103785

G5E9A7
DM1 locus, WD repeat containing

1

2

High-throughput

0.470

High

111182

I6L9F6
NEFL protein

1

3

High-throughput

0.470

High

132926

SDCB1
Syntenin-1

1

3

High-throughput

0.470

High

196632

ZBT24
Zinc finger and BTB domain-containing protein 24

1

2

High-throughput

0.470

High

207340

FRS3
Fibroblast growth factor receptor substrate 3

1

2

High-throughput

0.470

High

208050

HAIR
Lysine-specific demethylase hairless

1

1

High-throughput

0.470

High

231600

KIF1B
Kinesin-like protein KIF1B

1

3

High-throughput

0.470

High

270808

FOXH1
Forkhead box protein H1

1

3

High-throughput

0.470

High

308111

VENTX
Homeobox protein VENTX

1

3

High-throughput

0.470

High

324482

BAG3
BAG family molecular chaperone regulator 3

1

1

High-throughput

0.470

High

327087

GPAN1
G patch domain and ankyrin repeat-containing protein 1

1

3

High-throughput

0.470

High

327901

TBX6
T-box transcription factor TBX6

1

1

High-throughput

0.470

High

330428

HAND1
Heart- and neural crest derivatives-expressed protein 1

1

1

High-throughput

0.470

High

446905

HXC4
Homeobox protein Hox-C4

1

2

High-throughput

0.470

High

638333

RBTN2
Rhombotin-2

1

3

High-throughput

0.470

High

670361

AQP1
Aquaporin-1

1

1

High-throughput

0.470

High

678944

HXC8
Homeobox protein Hox-C8

1

2

High-throughput

0.470

High

703404

CSTF2
Cleavage stimulation factor subunit 2

1

1

High-throughput

0.470

High

818882

RXRG
Retinoic acid receptor RXR-gamma

1

3

High-throughput

0.470

High

849783

SUOX
Sulfite oxidase, mitochondrial

1

1

High-throughput

0.470

High

868587

ATX1
Ataxin-1

1

1

High-throughput

0.470

High

941924

PITX1
Pituitary homeobox 1

1

1

High-throughput

0.470

High

944053

PO6F2
POU domain, class 6, transcription factor 2

1

1

High-throughput

0.470

High

978207

ARI5A
AT-rich interactive domain-containing protein 5A

1

1

High-throughput

0.470

High

993485

TLE5
TLE family member 5

1

1

High-throughput

0.470

High

1022140

NFX1
Transcriptional repressor NF-X1

1

3

High-throughput

0.470

High

1044786

RIN1
Ras and Rab interactor 1

1

3

High-throughput

0.470

High

1048545

VEZF1
Vascular endothelial zinc finger 1

1

5

High-throughput

0.470

High

1061349

NR1D2
Nuclear receptor subfamily 1 group D member 2

1

3

High-throughput

0.470

High

1079935

RB11B
Ras-related protein Rab-11B

1

3

High-throughput

0.470

High

1080602

ZIC1
Zinc finger protein ZIC 1

1

3

High-throughput

0.470

High

1092962

LONF2
LON peptidase N-terminal domain and RING finger protein 2

1

1

High-throughput

0.470

High

1110170

T10IP
Testis-specific protein 10-interacting protein

1

1

High-throughput

0.470

High

1135812

DCAF8
DDB1- and CUL4-associated factor 8

1

1

High-throughput

0.470

High

1144440

TSH3
Teashirt homolog 3

1

1

High-throughput

0.470

High

1148475

LHX8
LIM/homeobox protein Lhx8

1

1

High-throughput

0.470

High

1157415

PPR18
Phostensin

1

1

High-throughput

0.470

High

1158727

CA094
Uncharacterized protein C1orf94

1

1

High-throughput

0.470

High

1161927

FOXR1
Forkhead box protein R1

1

1

High-throughput

0.470

High

1167649

ASCL4
Achaete-scute homolog 4

1

1

High-throughput

0.470

High

1169138

ZFP2
Zinc finger protein ZFP2

1

1

High-throughput

0.470

High

1169299

RUFY4
RUN and FYVE domain-containing protein 4

1

1

High-throughput

0.470

High

1169867

PKHG7
Pleckstrin homology domain-containing family G member 7

1

2

High-throughput

0.470

High

1184434

ZN765
Zinc finger protein 765

1

1

High-throughput

0.470

High

1189169

SAMD7
Sterile alpha motif domain-containing protein 7

1

4

High-throughput

0.470

High

1189235

POGZ
Pogo transposable element with ZNF domain

1

2

High-throughput

0.470

High

1191281

SAXO4
Stabilizer of axonemal microtubules 4

1

1

High-throughput

0.470

High

1191432

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.470

High

1192053

AP2D
Transcription factor AP-2-delta

1

1

High-throughput

0.470

High

1198351

PATL1
Protein PAT1 homolog 1

1

2

High-throughput

0.470

High

1201356

IGFN1
Immunoglobulin-like and fibronectin type III domain-containing protein 1

1

1

High-throughput

0.470

High

1203606

ZN444
Zinc finger protein 444

1

1

High-throughput

0.470

High

1203607

ZN366
Zinc finger protein 366

1

1

High-throughput

0.470

High

1203608

GMCL2
Germ cell-less protein-like 2

1

2

High-throughput

0.470

High

1203609

VP37A
Vacuolar protein sorting-associated protein 37A

1

2

High-throughput

0.470

High

1203610

ZN417
Zinc finger protein 417

1

4

High-throughput

0.470

High

1203612

LNX1
E3 ubiquitin-protein ligase LNX

1

3

High-throughput

0.470

High

1203613

MYOZ3
Myozenin-3

1

1

High-throughput

0.470

High

1203614

F222B
Protein FAM222B

1

1

High-throughput

0.470

High

1203618

SHC3
SHC-transforming protein 3

1

1

High-throughput

0.470

High

1203619

RBPMS
RNA-binding protein with multiple splicing

1

1

High-throughput

0.470

High

1203621

LENG1
Leukocyte receptor cluster member 1

1

1

High-throughput

0.470

High

1203624

CC120
Coiled-coil domain-containing protein 120

1

1

High-throughput

0.470

High

1203627

SAM11
Sterile alpha motif domain-containing protein 11

1

4

High-throughput

0.470

High

1203628

ZN587
Zinc finger protein 587

1

3

High-throughput

0.470

High

1203630

F110A
Protein FAM110A

1

1

High-throughput

0.470

High

1203632

GLIS2
Zinc finger protein GLIS2

1

4

High-throughput

0.470

High

1203633

ENKD1
Enkurin domain-containing protein 1

1

1

High-throughput

0.470

High

1203634

SMG9
Nonsense-mediated mRNA decay factor SMG9

1

1

High-throughput

0.470

High

1203636

LHX5
LIM/homeobox protein Lhx5

1

1

High-throughput

0.470

High

1203637

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

1

5

High-throughput

0.470

High

1203638

TF7L2
Transcription factor 7-like 2

1

2

High-throughput

0.470

High

1203639

DMRT3
Doublesex- and mab-3-related transcription factor 3

1

1

High-throughput

0.470

High

1203640

PAR11
Protein mono-ADP-ribosyltransferase PARP11

1

1

High-throughput

0.470

High

1203641

CCL28
C-C motif chemokine 28

1

1

High-throughput

0.470

High

1203645

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

1

High-throughput

0.470

High

1203646

MAGC2
Melanoma-associated antigen C2

1

2

High-throughput

0.470

High

1203648

KLH20
Kelch-like protein 20

1

1

High-throughput

0.470

High

1203651

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

1

High-throughput

0.470

High

58404

A2RU56
LOC401296 protein

1

0

High-throughput

0.268

Low

130078

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.268

Low

151321

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.268

Low

281729

WFS1
Wolframin

1

0

High-throughput

0.268

Low

318499

CDS2
Phosphatidate cytidylyltransferase 2

1

0

High-throughput

0.268

Low

388561

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.268

Low

602858

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

High-throughput

0.268

Low

642823

ASPX
Acrosomal protein SP-10

1

0

High-throughput

0.268

Low

768441

CAPG
Macrophage-capping protein

1

0

High-throughput

0.268

Low

803624

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.268

Low

814008

RGR
RPE-retinal G protein-coupled receptor

1

0

High-throughput

0.268

Low

893399

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.268

Low

1055900

ZN345
Zinc finger protein 345

1

0

High-throughput

0.268

Low

1089472

FA98C
Protein FAM98C

1

0

High-throughput

0.268

Low

1129203

CD158
Coiled-coil domain-containing protein 158

1

0

High-throughput

0.268

Low

1151613

OTU7B
OTU domain-containing protein 7B

1

0

High-throughput

0.268

Low

1174049

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

1

0

High-throughput

0.268

Low

1174907

TMUB2
Transmembrane and ubiquitin-like domain-containing protein 2

1

0

High-throughput

0.268

Low

1202896

SPA24
Spermatogenesis-associated protein 24

1

0

High-throughput

0.268

Low

1203430

TRI69
E3 ubiquitin-protein ligase TRIM69

1

0

High-throughput

0.268

Low

1203602

CRLF3
Cytokine receptor-like factor 3

1

0

High-throughput

0.268

Low

1203603

HID1
Protein HID1

1

0

High-throughput

0.268

Low

1203604

SLN12
Ribonuclease SLFN12

1

0

High-throughput

0.268

Low

1203605

TMM61
Transmembrane protein 61

1

0

High-throughput

0.268

Low

1203611

CX038
Uncharacterized protein CXorf38

1

0

High-throughput

0.268

Low

1203615

RN138
E3 ubiquitin-protein ligase RNF138

1

0

High-throughput

0.268

Low

1203616

ATLA1
Atlastin-1

1

0

High-throughput

0.268

Low

1203620

COQA1
Collagen alpha-1(XXVI) chain

1

0

High-throughput

0.268

Low

1203622

RN183
E3 ubiquitin-protein ligase RNF183

1

0

High-throughput

0.268

Low

1203623

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.268

Low

1203625

CH048
Uncharacterized protein C8orf48

1

0

High-throughput

0.268

Low

1203626

ZN488
Zinc finger protein 488

1

0

High-throughput

0.268

Low

1203631

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.268

Low

1203635

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

0

High-throughput

0.268

Low

1203642

RFOX1
RNA binding protein fox-1 homolog 1

1

0

High-throughput

0.268

Low

1203643

GPT2L
G patch domain-containing protein 2-like

1

0

High-throughput

0.268

Low

1203644

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

1

0

High-throughput

0.268

Low

1203647

CHIP
E3 ubiquitin-protein ligase CHIP

1

0

High-throughput

0.268

Low

1203649

RNF11
RING finger protein 11

1

0

High-throughput

0.268

Low

1203650

MOFA1
MORF4 family-associated protein 1

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024