Protein: TMM59
Transmembrane protein 59 (Liver membrane-bound protein)

Gene: TMM59, TMEM59
Organism: Homo sapiens
Interactions: 184
UniProt ID: Q9BXS4

Gene Ontology (top 5):
GO:0000137 - Golgi cis cisterna
GO:0000138 - Golgi trans cisterna
GO:0000139 - Golgi membrane
GO:0004175 - endopeptidase activity
GO:0005764 - lysosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1166644

I20RB
Interleukin-20 receptor subunit beta

3

1

High-throughput

0.667

High

1146807

A16L1
Autophagy-related protein 16-1

3

0

Small-scale

0.636

High

1315670

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

2

1

High-throughput

0.611

High

1315669

CC50A
Cell cycle control protein 50A

2

0

High-throughput

0.585

High

1315657

SG196
Protein O-mannose kinase

2

1

High-throughput

0.574

High

146397

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

1

High-throughput

0.536

High

197137

SIA8C
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3

1

2

High-throughput

0.536

High

199605

B4GT5
Beta-1,4-galactosyltransferase 5

1

4

High-throughput

0.536

High

225309

H6ST1
Heparan-sulfate 6-O-sulfotransferase 1

1

1

High-throughput

0.536

High

234634

MA1A2
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

1

1

High-throughput

0.536

High

236329

B4GT3
Beta-1,4-galactosyltransferase 3

1

4

High-throughput

0.536

High

295766

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

2

High-throughput

0.536

High

508179

FGFR1
Fibroblast growth factor receptor 1

1

2

High-throughput

0.536

High

546671

B4GT1
Beta-1,4-galactosyltransferase 1

1

4

High-throughput

0.536

High

567248

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.536

High

608107

FGFR4
Fibroblast growth factor receptor 4

1

2

High-throughput

0.536

High

621818

PRTN3
Myeloblastin

1

2

High-throughput

0.536

High

661122

CD1B
T-cell surface glycoprotein CD1b

1

4

High-throughput

0.536

High

708162

MA1A1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

1

1

High-throughput

0.536

High

734424

CXG1
Gap junction gamma-1 protein

1

1

High-throughput

0.536

High

1040086

MTR1L
Melatonin-related receptor

1

1

High-throughput

0.536

High

1067605

P2RY6
P2Y purinoceptor 6

1

2

High-throughput

0.536

High

1129038

COL12
Collectin-12

1

1

High-throughput

0.536

High

1190281

LRP10
Low-density lipoprotein receptor-related protein 10

1

2

High-throughput

0.536

High

1204035

CHSS1
Chondroitin sulfate synthase 1

1

2

High-throughput

0.536

High

1224340

AGRG5
Adhesion G-protein coupled receptor G5

1

1

High-throughput

0.536

High

1235964

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

1

1

High-throughput

0.536

High

1255982

RN128
E3 ubiquitin-protein ligase RNF128

1

2

High-throughput

0.536

High

1265340

SIA8B
Alpha-2,8-sialyltransferase 8B

1

2

High-throughput

0.536

High

1282595

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

2

High-throughput

0.536

High

1297953

H6ST2
Heparan-sulfate 6-O-sulfotransferase 2

1

1

High-throughput

0.536

High

1315654

CHST8
Carbohydrate sulfotransferase 8

1

2

High-throughput

0.536

High

1315662

CHSTB
Carbohydrate sulfotransferase 11

1

2

High-throughput

0.536

High

1315663

B3GA2
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2

1

2

High-throughput

0.536

High

1315665

CHSTC
Carbohydrate sulfotransferase 12

1

2

High-throughput

0.536

High

1315673

GGA3
ADP-ribosylation factor-binding protein GGA3

1

1

High-throughput

0.536

High

1315676

B4GT7
Beta-1,4-galactosyltransferase 7

1

4

High-throughput

0.536

High

1315677

B4GT6
Beta-1,4-galactosyltransferase 6

1

4

High-throughput

0.536

High

1315687

A4GCT
Alpha-1,4-N-acetylglucosaminyltransferase

1

1

High-throughput

0.536

High

1315694

LRP12
Low-density lipoprotein receptor-related protein 12

1

2

High-throughput

0.536

High

1315695

PCDA8
Protocadherin alpha-8

1

1

High-throughput

0.536

High

1263896

CLC4D
C-type lectin domain family 4 member D

1

2

High-throughput

0.515

High

1315666

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.515

High

1315686

CLC4E
C-type lectin domain family 4 member E

1

2

High-throughput

0.515

High

129422

GOLI4
Golgi integral membrane protein 4

1

0

High-throughput

0.513

High

131954

UPK2
Uroplakin-2

1

0

High-throughput

0.513

High

152101

TOR1B
Torsin-1B

1

0

High-throughput

0.513

High

154411

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

0

High-throughput

0.513

High

206522

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.513

High

238911

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.513

High

253879

FKTN
Ribitol-5-phosphate transferase FKTN

1

0

High-throughput

0.513

High

261713

VAMP4
Vesicle-associated membrane protein 4

1

0

High-throughput

0.513

High

300362

AGRL1
Adhesion G protein-coupled receptor L1

1

0

High-throughput

0.513

High

300684

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.513

High

309616

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.513

High

361518

APOE
Apolipoprotein E

1

0

High-throughput

0.513

High

433464

YES
Tyrosine-protein kinase Yes

1

0

High-throughput

0.513

High

474774

CFC1
Cryptic protein

1

0

High-throughput

0.513

High

488364

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.513

High

585615

FUT1
Galactoside alpha-(1,2)-fucosyltransferase 1

1

0

High-throughput

0.513

High

643238

MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

0

High-throughput

0.513

High

738408

BMR1A
Bone morphogenetic protein receptor type-1A

1

0

High-throughput

0.513

High

783269

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

0

High-throughput

0.513

High

830103

MA2A2
Alpha-mannosidase 2x

1

0

High-throughput

0.513

High

839411

S26A2
Sulfate transporter

1

0

High-throughput

0.513

High

846629

MMP15
Matrix metalloproteinase-15

1

0

High-throughput

0.513

High

895727

CXCR4
C-X-C chemokine receptor type 4

1

0

High-throughput

0.513

High

957925

EFNB1
Ephrin-B1

1

0

High-throughput

0.513

High

980122

ATP7A
Copper-transporting ATPase 1

1

0

High-throughput

0.513

High

998434

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

0

High-throughput

0.513

High

1013947

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.513

High

1016022

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

0

High-throughput

0.513

High

1016102

SRBP2
Sterol regulatory element-binding protein 2

1

0

High-throughput

0.513

High

1023325

TRI32
E3 ubiquitin-protein ligase TRIM32

1

0

High-throughput

0.513

High

1032025

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

0

High-throughput

0.513

High

1034727

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

0

High-throughput

0.513

High

1065995

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

1081869

EXT1
Exostosin-1

1

0

High-throughput

0.513

High

1086556

AT2B3
Plasma membrane calcium-transporting ATPase 3

1

0

High-throughput

0.513

High

1086571

CEGT
Ceramide glucosyltransferase

1

0

High-throughput

0.513

High

1147998

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

0

High-throughput

0.513

High

1165049

KCNT2
Potassium channel subfamily T member 2

1

0

High-throughput

0.513

High

1170020

QSOX2
Sulfhydryl oxidase 2

1

0

High-throughput

0.513

High

1201485

LAP4B
Lysosomal-associated transmembrane protein 4B

1

0

High-throughput

0.513

High

1239858

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.513

High

1240569

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

1

0

High-throughput

0.513

High

1253828

SPPL3
Signal peptide peptidase-like 3

1

0

High-throughput

0.513

High

1260048

CHPT1
Cholinephosphotransferase 1

1

0

High-throughput

0.513

High

1306362

ABCA3
Phospholipid-transporting ATPase ABCA3

1

0

High-throughput

0.513

High

1310425

PGAP4
Post-GPI attachment to proteins factor 4

1

0

High-throughput

0.513

High

1312349

TMM43
Transmembrane protein 43

1

0

High-throughput

0.513

High

1315658

FKRP
Ribitol 5-phosphate transferase FKRP

1

0

High-throughput

0.513

High

1315661

ABCB6
ATP-binding cassette sub-family B member 6

1

0

High-throughput

0.513

High

1315674

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.513

High

1315681

TM59L
Transmembrane protein 59-like

1

0

High-throughput

0.513

High

1315684

DSE
Dermatan-sulfate epimerase

1

0

High-throughput

0.513

High

1315685

VANG2
Vang-like protein 2

1

0

High-throughput

0.513

High

1315688

STX8
Syntaxin-8

1

0

High-throughput

0.513

High

1315690

UST
Uronyl 2-sulfotransferase

1

0

High-throughput

0.513

High

1315691

S27A6
Long-chain fatty acid transport protein 6

1

0

High-throughput

0.513

High

1315692

NSG2
Neuronal vesicle trafficking-associated protein 2

1

0

High-throughput

0.513

High

1315693

ZDHC9
Palmitoyltransferase ZDHHC9

1

0

High-throughput

0.513

High

1315696

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

0

High-throughput

0.513

High

1315697

ENPP4
Bis(5'-adenosyl)-triphosphatase ENPP4

1

0

High-throughput

0.513

High

648873

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.493

High

121626

CORT
Cortistatin [Cleaved into: Cortistatin-29; Cortistatin-17]

1

1

High-throughput

0.489

High

514469

PSPC
Surfactant protein C

1

1

High-throughput

0.489

High

1083599

SGCA
Alpha-sarcoglycan

1

1

High-throughput

0.489

High

1088469

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

1

High-throughput

0.489

High

1108804

CEA21
Carcinoembryonic antigen-related cell adhesion molecule 21

1

1

High-throughput

0.489

High

1203316

IFNE
Interferon epsilon

1

1

High-throughput

0.489

High

1223999

NRSN1
Neurensin-1

1

1

High-throughput

0.489

High

1261705

LMBR1
Limb region 1 protein homolog

1

1

High-throughput

0.489

High

1312902

ABHEA
Protein ABHD14A

1

1

High-throughput

0.489

High

1315660

UD17
UDP-glucuronosyltransferase 1A7

1

1

High-throughput

0.489

High

1315667

CBLN4
Cerebellin-4

1

1

High-throughput

0.489

High

1315680

GGA1
ADP-ribosylation factor-binding protein GGA1

1

1

High-throughput

0.489

High

1315682

DKKL1
Dickkopf-like protein 1

1

1

High-throughput

0.489

High

205931

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

385469

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

436489

RHOC
Rho-related GTP-binding protein RhoC

1

3

High-throughput

0.479

High

474536

GPHRB
Golgi pH regulator B

1

1

High-throughput

0.479

High

564669

RHOQ
Rho-related GTP-binding protein RhoQ

1

5

High-throughput

0.479

High

713867

RYK
Tyrosine-protein kinase RYK

1

4

Small-scale

0.479

High

892571

RAC3
Ras-related C3 botulinum toxin substrate 3

1

4

High-throughput

0.479

High

915939

RHOB
Rho-related GTP-binding protein RhoB

1

4

High-throughput

0.479

High

951291

RHOG
Rho-related GTP-binding protein RhoG

1

3

High-throughput

0.479

High

1076738

RHOH
Rho-related GTP-binding protein RhoH

1

5

High-throughput

0.479

High

1165929

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1183537

RHOU
Rho-related GTP-binding protein RhoU

1

5

High-throughput

0.479

High

1198160

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.479

High

1240757

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.479

High

1269214

RND1
Rho-related GTP-binding protein Rho6

1

4

High-throughput

0.479

High

1287483

AP2M1
AP-2 complex subunit mu

1

1

Small-scale

0.479

High

1315650

AP1M1
AP-1 complex subunit mu-1

1

1

Small-scale

0.479

High

1315656

RHOJ
Rho-related GTP-binding protein RhoJ

1

5

High-throughput

0.479

High

1315675

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.479

High

1315679

ERRFI
ERBB receptor feedback inhibitor 1

1

0

Small-scale

0.460

High

526048

IFM1
Interferon-induced transmembrane protein 1

1

0

High-throughput

0.458

High

545027

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

1036867

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1087604

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

1222695

TM192
Transmembrane protein 192

1

0

High-throughput

0.458

High

1252198

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.458

High

1315652

KPCD2
Serine/threonine-protein kinase D2

1

0

High-throughput

0.458

High

1315653

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

1315655

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.458

High

81840

GPHRA
Golgi pH regulator A

1

1

High-throughput

0.445

High

354986

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

2

High-throughput

0.445

High

1204830

GOLI
E3 ubiquitin-protein ligase RNF130

1

2

High-throughput

0.437

High

326285

TSN12
Tetraspanin-12

1

0

Small-scale

0.426

High

1044119

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.282

High

58461

F234B
Protein FAM234B

1

0

High-throughput

0.279

Low

213277

SNG3
Synaptogyrin-3

1

0

High-throughput

0.279

Low

214787

PM34
Peroxisomal membrane protein PMP34

1

0

High-throughput

0.279

Low

322028

ZMYM6
Zinc finger MYM-type protein 6

1

0

High-throughput

0.279

Low

362407

CRP

1

0

High-throughput

0.279

Low

592797

MCH
Pro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid

1

0

High-throughput

0.279

Low

726541

TIMP3
Metalloproteinase inhibitor 3

1

0

High-throughput

0.279

Low

764687

CUX1
Homeobox protein cut-like 1

1

0

High-throughput

0.279

Low

821510

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

0

High-throughput

0.279

Low

839345

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

High-throughput

0.279

Low

1054741

EP3A
Epididymal secretory protein E3-alpha

1

0

High-throughput

0.279

Low

1134700

DIK1A
Divergent protein kinase domain 1A

1

0

High-throughput

0.279

Low

1145413

LPCT4
Lysophospholipid acyltransferase LPCAT4

1

0

High-throughput

0.279

Low

1147563

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

0

High-throughput

0.279

Low

1185353

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

0

High-throughput

0.279

Low

1192852

TMED4
Transmembrane emp24 domain-containing protein 4

1

0

High-throughput

0.279

Low

1202417

FJX1
Four-jointed box protein 1

1

0

High-throughput

0.279

Low

1216877

EPHX4
Epoxide hydrolase 4

1

0

High-throughput

0.279

Low

1239203

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.279

Low

1315651

EMIL2
EMILIN-2

1

0

High-throughput

0.279

Low

1315659

CAHM2
Calcium homeostasis modulator protein 2

1

0

High-throughput

0.279

Low

1315664

ENTP7
Ectonucleoside triphosphate diphosphohydrolase 7

1

0

High-throughput

0.279

Low

1315672

IL20
Interleukin-20

1

0

High-throughput

0.279

Low

1315683

POMT2
Protein O-mannosyl-transferase 2

1

0

High-throughput

0.279

Low

1315689

CP131
Centrosomal protein of 131 kDa

1

0

High-throughput

0.279

Low

1315678

PARP2
Poly [ADP-ribose] polymerase 2

1

0

Small-scale

0.261

Low

1032805

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

1

0

High-throughput

0.249

Low

1061599

CUL7
Cullin-7

1

0

High-throughput

0.249

Low

1269525

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

1311685

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low

1315668

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

1

0

High-throughput

0.249

Low

1315671

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024