Protein: HSPB2
Heat shock protein beta-2 (HspB2) (DMPK-binding protein) (MKBP) (Heat shock protein family B member 2)

Gene: HSPB2
Organism: Homo sapiens
Interactions: 148
UniProt ID: Q16082

Gene Ontology (top 5):
GO:0005212 - structural constituent of eye lens
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006986 - response to unfolded protein

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

359021

CRYAB
Alpha-crystallin B chain

5

16

Small-scale

0.929

High

1080914

HSPB8
Heat shock protein beta-8

2

16

Small-scale

0.817

High

1080859

HSPB2
Heat shock protein beta-2

2

16

Small-scale

0.809

High

358767

CRYAA
Alpha-crystallin A chain

1

15

Small-scale

0.713

High

388468

HSPB1
Heat shock protein beta-1

1

16

High-throughput

0.691

High

324422

BAG3
BAG family molecular chaperone regulator 3

3

9

High-throughput

0.665

High

997636

DMPK
Myotonin-protein kinase

2

6

Small-scale

0.633

High

1022259

HSPB3
Heat shock protein beta-3

1

18

Small-scale

0.618

High

272938

RFPL3
Ret finger protein-like 3

2

2

High-throughput

0.606

High

638507

RBTN1
Rhombotin-1

2

5

High-throughput

0.606

High

1048537

VEZF1
Vascular endothelial zinc finger 1

2

3

High-throughput

0.606

High

1080865

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

7

High-throughput

0.606

High

1080871

POGZ
Pogo transposable element with ZNF domain

2

3

High-throughput

0.606

High

1080879

LMO3
LIM domain only protein 3

2

5

High-throughput

0.606

High

1080893

BEX2
Protein BEX2

2

1

High-throughput

0.606

High

1080902

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

2

2

High-throughput

0.606

High

1080906

A1CF
APOBEC1 complementation factor

2

3

High-throughput

0.606

High

1080911

WWOX
WW domain-containing oxidoreductase

2

2

High-throughput

0.606

High

930236

UBC9
SUMO-conjugating enzyme UBC9

2

6

Small-scale

0.584

High

211861

TLX3
T-cell leukemia homeobox protein 3

2

0

High-throughput

0.580

High

567845

HXB9
Homeobox protein Hox-B9

2

0

High-throughput

0.580

High

1080887

CEP19
Centrosomal protein of 19 kDa

2

0

High-throughput

0.580

High

1048077

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

3

Small-scale

0.561

High

1080872

MISP
Mitotic interactor and substrate of PLK1

2

1

High-throughput

0.553

High

898129

MAX
Protein max

1

4

High-throughput

0.536

High

1080870

MCAF1
Activating transcription factor 7-interacting protein 1

1

3

High-throughput

0.536

High

1080888

BTBD9
BTB/POZ domain-containing protein 9

1

3

High-throughput

0.536

High

1080894

PCGF6
Polycomb group RING finger protein 6

1

4

High-throughput

0.536

High

1080897

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

3

High-throughput

0.536

High

1080904

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

2

High-throughput

0.536

High

1080916

TRI33
E3 ubiquitin-protein ligase TRIM33

1

9

High-throughput

0.536

High

394778

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.515

High

949112

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.513

High

1080875

MGAP
MAX gene-associated protein

1

0

High-throughput

0.513

High

1080884

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

0

High-throughput

0.513

High

1080901

CSR2B
Cysteine-rich protein 2-binding protein

1

0

High-throughput

0.513

High

1080907

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.513

High

174295

TELT
Telethonin

1

2

High-throughput

0.508

High

254093

WDR1
WD repeat-containing protein 1

1

3

High-throughput

0.508

High

355218

MYG
Myoglobin

1

2

High-throughput

0.508

High

375951

ALDOA
Fructose-bisphosphate aldolase A

1

2

High-throughput

0.508

High

382004

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

3

High-throughput

0.508

High

417082

KCRM
Creatine kinase M-type

1

2

High-throughput

0.508

High

417299

ENOA
Alpha-enolase

1

2

High-throughput

0.508

High

449270

LEG1
Galectin-1

1

4

High-throughput

0.508

High

505405

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

2

High-throughput

0.508

High

528375

MYH6
Myosin-6

1

9

High-throughput

0.508

High

534025

ENOB
Beta-enolase

1

2

High-throughput

0.508

High

659286

DUS1
Dual specificity protein phosphatase 1

1

6

High-throughput

0.508

High

737553

PGM1
Phosphoglucomutase-1

1

1

High-throughput

0.508

High

777454

MDHC
Malate dehydrogenase, cytoplasmic

1

2

High-throughput

0.508

High

782910

GARS
Glycine--tRNA ligase

1

1

High-throughput

0.508

High

875974

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

1

High-throughput

0.508

High

878320

NH2L1
NHP2-like protein 1

1

1

High-throughput

0.508

High

891794

ACTB
Actin, cytoplasmic 1

1

5

High-throughput

0.508

High

901876

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

1

High-throughput

0.508

High

923036

RL11
Large ribosomal subunit protein uL5

1

2

High-throughput

0.508

High

929876

ACTG
Actin, cytoplasmic 2

1

5

High-throughput

0.508

High

932183

ACTC
Actin, alpha cardiac muscle 1

1

5

High-throughput

0.508

High

932719

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.508

High

932984

ACTS
Actin, alpha skeletal muscle

1

5

High-throughput

0.508

High

1050648

FHL2
Four and a half LIM domains protein 2

1

6

High-throughput

0.508

High

1051291

DCTN1
Dynactin subunit 1

1

10

High-throughput

0.508

High

1051868

IF4A2
Eukaryotic initiation factor 4A-II

1

3

High-throughput

0.508

High

1052881

FLNC
Filamin-C

1

15

High-throughput

0.508

High

1060194

MYPC3
Myosin-binding protein C, cardiac-type

1

8

High-throughput

0.508

High

1078293

MLF2
Myeloid leukemia factor 2

1

3

High-throughput

0.508

High

1080877

PPM1K
Protein phosphatase Mn(2+)-dependent 1K

1

1

High-throughput

0.508

High

1080878

CMYA5
Cardiomyopathy-associated protein 5

1

6

High-throughput

0.508

High

1080881

TITIN
Titin

1

10

High-throughput

0.508

High

1080883

RL36L
Ribosomal protein eL42-like

1

2

High-throughput

0.508

High

1080891

PKP2
Plakophilin-2

1

6

High-throughput

0.508

High

1080898

TXNIP
Thioredoxin-interacting protein

1

4

High-throughput

0.508

High

1080899

ZN335
Zinc finger protein 335

1

4

High-throughput

0.508

High

1080903

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

2

High-throughput

0.508

High

1080909

BEX4
Protein BEX4

1

1

High-throughput

0.508

High

742318

SYUA
Alpha-synuclein

1

4

Small-scale

0.501

High

1080874

MAPK5
MAP kinase-activated protein kinase 5

1

8

Small-scale

0.501

High

1080885

C102A
Coiled-coil domain-containing protein 102A

1

10

High-throughput

0.489

High

1080915

YETS2
YEATS domain-containing protein 2

1

1

High-throughput

0.489

High

126694

DCTN6
Dynactin subunit 6

1

0

High-throughput

0.486

High

213828

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.486

High

813042

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.486

High

911397

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.486

High

1037471

ASAH1
Acid ceramidase

1

0

High-throughput

0.486

High

1080864

THMS2
Protein THEMIS2

1

0

High-throughput

0.486

High

1080869

TATD1
Deoxyribonuclease TATDN1

1

0

High-throughput

0.486

High

1080908

PARVA
Alpha-parvin

1

0

High-throughput

0.486

High

1080910

DDIT4
DNA damage-inducible transcript 4 protein

1

0

High-throughput

0.486

High

1080912

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

0

High-throughput

0.486

High

426907

CRGC
Gamma-crystallin C

1

13

Small-scale

0.481

High

584297

TNNI3
Troponin I, cardiac muscle

1

2

High-throughput

0.481

High

736115

VATE1
V-type proton ATPase subunit E 1

1

1

High-throughput

0.481

High

949686

RL36A
Large ribosomal subunit protein eL42

1

2

High-throughput

0.481

High

1080895

UBL5
Ubiquitin-like protein 5

1

3

Small-scale

0.481

High

200179

TGFI1
Transforming growth factor beta-1-induced transcript 1 protein

1

7

Small-scale

0.479

High

487477

ANDR
Androgen receptor

1

5

Small-scale

0.479

High

519854

GRAA
Granzyme A

1

1

Small-scale

0.479

High

529174

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

Small-scale

0.479

High

961134

HSF1
Heat shock factor protein 1

1

1

Small-scale

0.479

High

1020681

TRAF2
TNF receptor-associated factor 2

1

2

Small-scale

0.479

High

1080913

DAXX
Death domain-associated protein 6

1

1

Small-scale

0.479

High

1080917

TRAF6
TNF receptor-associated factor 6

1

4

Small-scale

0.479

High

152375

ABCD4
Lysosomal cobalamin transporter ABCD4

1

1

High-throughput

0.464

High

396473

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

1

High-throughput

0.464

High

636938

ATPA
ATP synthase subunit alpha, mitochondrial

1

2

High-throughput

0.464

High

790251

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

1

High-throughput

0.464

High

869997

MYOM2
Myomesin-2

1

8

High-throughput

0.464

High

1080880

AGA11
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 11

1

8

High-throughput

0.464

High

1080882

RYR2
Ryanodine receptor 2

1

1

High-throughput

0.464

High

1080900

NT5D2
5'-nucleotidase domain-containing protein 2

1

2

High-throughput

0.464

High

416991

IF4E
Eukaryotic translation initiation factor 4E

1

0

Small-scale

0.458

High

58739

A2VCT2
2-oxoglutarate dehydrogenase complex component E1

1

3

High-throughput

0.457

High

111346

J3KQN4
Large ribosomal subunit protein eL42

1

2

High-throughput

0.457

High

429319

SAP
Prosaposin

1

2

High-throughput

0.457

High

531164

EF2
Elongation factor 2

1

1

High-throughput

0.457

High

1080862

Q53Y06
V-type proton ATPase subunit E 1

1

1

High-throughput

0.457

High

1080873

Q8IW09
ZNF335 protein

1

4

High-throughput

0.457

High

677980

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

1

High-throughput

0.439

High

898016

YPEL3
Protein yippee-like 3

1

2

High-throughput

0.439

High

1080861

KGUA
Guanylate kinase

1

0

High-throughput

0.438

High

61510

A5YM51
Myosin-7

1

9

High-throughput

0.417

High

90121

D6RFM5
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

1

High-throughput

0.417

High

1080863

Q5BJH1
Prosaposin

1

2

High-throughput

0.417

High

1080867

Q6FGX2
Troponin I, cardiac muscle

1

2

High-throughput

0.417

High

474602

PRR35
Proline-rich protein 35

2

0

High-throughput

0.316

High

1080866

BICRL
BRD4-interacting chromatin-remodeling complex-associated protein-like

2

0

High-throughput

0.316

High

1080889

SNX18
Sorting nexin-18

2

0

High-throughput

0.316

High

1080896

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.316

High

1080876

ZZZ3
ZZ-type zinc finger-containing protein 3

1

0

High-throughput

0.279

Low

1080886

COA7
Cytochrome c oxidase assembly factor 7

1

0

High-throughput

0.279

Low

238940

ABCC9
ATP-binding cassette sub-family C member 9

1

0

High-throughput

0.265

Low

335675

COX1
Cytochrome c oxidase subunit 1

1

0

High-throughput

0.265

Low

335821

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.265

Low

335989

COX3
Cytochrome c oxidase subunit 3

1

0

High-throughput

0.265

Low

344497

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.265

Low

362472

C1QA
Complement C1q subcomponent subunit A

1

0

High-throughput

0.265

Low

427086

CATD
Cathepsin D

1

0

High-throughput

0.265

Low

431231

CATB
Cathepsin B

1

0

High-throughput

0.265

Low

533470

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.265

Low

601632

PGS1
Biglycan

1

0

High-throughput

0.265

Low

881392

NDUA6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6

1

0

High-throughput

0.265

Low

1080860

CP1B1
Cytochrome P450 1B1

1

0

High-throughput

0.265

Low

1080890

SDF2
Stromal cell-derived factor 2

1

0

High-throughput

0.265

Low

1080892

THUM2
THUMP domain-containing protein 2

1

0

High-throughput

0.265

Low

1080905

MYOZ2
Myozenin-2

1

0

High-throughput

0.265

Low

1080868

Q6LEU2
Sodium/potassium-transporting ATPase subunit beta

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024