Protein: PTN7
Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Hematopoietic protein-tyrosine phosphatase) (HEPTP) (Protein-tyrosine phosphatase LC-PTP)

Gene: PTN7, PTPN7
Organism: Homo sapiens
Interactions: 66
UniProt ID: P35236

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0004725 - protein tyrosine phosphatase activity
GO:0004726 - non-membrane spanning protein tyrosine phosphatase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

658812

MK01
Mitogen-activated protein kinase 1

7

20

Small-scale

0.755

High

647484

MK03
Mitogen-activated protein kinase 3

5

20

Small-scale

0.726

High

719341

MK14
Mitogen-activated protein kinase 14

5

20

Small-scale

0.711

High

338025

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.698

High

719339

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.698

High

435558

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.625

High

601826

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.625

High

665157

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.625

High

719335

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.625

High

719338

PTK7
Inactive tyrosine-protein kinase 7

1

20

High-throughput

0.625

High

719351

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.625

High

719324

PTN7
Tyrosine-protein phosphatase non-receptor type 7

1

19

High-throughput

0.618

High

719328

DHYS
Deoxyhypusine synthase

2

2

High-throughput

0.611

High

719359

GMCL1
Germ cell-less protein-like 1

3

2

High-throughput

0.597

High

719344

CCD57
Coiled-coil domain-containing protein 57

1

2

High-throughput

0.573

High

231066

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

2

High-throughput

0.536

High

330878

PAK4
Serine/threonine-protein kinase PAK 4

1

5

High-throughput

0.536

High

713913

HS71L
Heat shock 70 kDa protein 1-like

1

3

High-throughput

0.536

High

719325

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.536

High

719358

HS105
Heat shock protein 105 kDa

1

8

High-throughput

0.536

High

264855

MPPB
Mitochondrial-processing peptidase subunit beta

2

3

High-throughput

0.533

High

719337

MPPA
Mitochondrial-processing peptidase subunit alpha

2

3

High-throughput

0.533

High

719327

MAOX
NADP-dependent malic enzyme

1

0

High-throughput

0.513

High

394217

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

568563

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

2

Small-scale

0.501

High

580208

CADH2
Cadherin-2

1

20

High-throughput

0.501

High

719331

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

2

Small-scale

0.501

High

216460

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

1

High-throughput

0.479

High

236407

RNBP6
Ran-binding protein 6

1

11

High-throughput

0.479

High

672013

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

10

High-throughput

0.479

High

719326

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

3

High-throughput

0.479

High

719330

DCAF7
DDB1- and CUL4-associated factor 7

1

3

High-throughput

0.479

High

719332

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

2

High-throughput

0.479

High

719333

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

2

High-throughput

0.479

High

719340

MK11
Mitogen-activated protein kinase 11

1

20

High-throughput

0.479

High

719342

RBBP7
Histone-binding protein RBBP7

1

3

High-throughput

0.479

High

719343

MAPK3
MAP kinase-activated protein kinase 3

1

5

High-throughput

0.479

High

719345

PPCEL
Prolyl endopeptidase-like

1

3

High-throughput

0.479

High

719347

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

1

High-throughput

0.479

High

719349

DCA10
DDB1- and CUL4-associated factor 10

1

2

High-throughput

0.479

High

719350

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

2

High-throughput

0.479

High

719353

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

4

High-throughput

0.479

High

719354

AROS
Active regulator of SIRT1

1

1

High-throughput

0.479

High

719357

IPO4
Importin-4

1

12

High-throughput

0.479

High

719361

MACD1
ADP-ribose glycohydrolase MACROD1

1

1

High-throughput

0.479

High

719362

MEP50
Methylosome protein WDR77

1

1

High-throughput

0.479

High

719364

SAV1
Protein salvador homolog 1

1

3

High-throughput

0.479

High

719366

ARMX3
Armadillo repeat-containing X-linked protein 3

1

1

High-throughput

0.479

High

719346

Q53SE7
Germ cell-less homolog 1

1

2

High-throughput

0.470

High

58750

FUCM
Fucose mutarotase

1

0

High-throughput

0.458

High

295949

MTA2
Metastasis-associated protein MTA2

1

0

High-throughput

0.458

High

327641

ECD
Protein ecdysoneless homolog

1

0

High-throughput

0.458

High

557360

BGAL
Beta-galactosidase

1

0

High-throughput

0.458

High

631097

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

719329

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.458

High

719352

ACD11
Acyl-CoA dehydrogenase family member 11

1

0

High-throughput

0.458

High

719355

PTOV1
Prostate tumor-overexpressed gene 1 protein

1

0

High-throughput

0.458

High

719360

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

719363

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

719334

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

8

Small-scale

0.457

High

719348

PREP
Presequence protease, mitochondrial

1

3

High-throughput

0.437

High

719356

MISSL
MAPK-interacting and spindle-stabilizing protein-like

1

3

High-throughput

0.437

High

719365

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

5

High-throughput

0.437

High

719367

PNMA2
Paraneoplastic antigen Ma2

1

2

High-throughput

0.437

High

719336

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024