Protein: PSPC
Surfactant protein C (SP-C) (Pulmonary surfactant-associated protein C) (Pulmonary surfactant-associated proteolipid SPL(Val)) (SP5)

Gene: PSPC, SFTPC
Organism: Homo sapiens
Interactions: 227
UniProt ID: P11686

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005789 - endoplasmic reticulum membrane
GO:0007585 - respiratory gaseous exchange by respiratory system
GO:0042599 - lamellar body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

514332

PSPC
Surfactant protein C

5

0

High-throughput

0.884

High

514373

CXCL9
C-X-C motif chemokine 9

4

0

High-throughput

0.668

High

514336

PVR
Poliovirus receptor

3

1

High-throughput

0.665

High

514454

SC22A
Vesicle-trafficking protein SEC22a

3

0

High-throughput

0.646

High

177805

TMPS2
Transmembrane protease serine 2

2

5

High-throughput

0.606

High

409494

HEPS
Serine protease hepsin

2

4

High-throughput

0.606

High

514351

INGR2
Interferon gamma receptor 2

2

1

High-throughput

0.606

High

514361

MFAP3
Microfibril-associated glycoprotein 3

2

0

High-throughput

0.602

High

514491

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

2

0

High-throughput

0.602

High

501610

BIP
Endoplasmic reticulum chaperone BiP

2

0

Small-scale

0.585

High

514397

MKS3
Meckelin

2

0

Small-scale

0.585

High

514337

MUC1
Mucin-1

2

0

High-throughput

0.580

High

514427

GOLM1
Golgi membrane protein 1

2

0

High-throughput

0.580

High

514441

MO2R1
Cell surface glycoprotein CD200 receptor 1

2

0

High-throughput

0.580

High

514468

T106C
Transmembrane protein 106C

2

0

High-throughput

0.580

High

311041

MPZL1
Myelin protein zero-like protein 1

2

2

High-throughput

0.574

High

315956

CBX6
Chromobox protein homolog 6

2

2

High-throughput

0.574

High

514419

PHC2
Polyhomeotic-like protein 2

2

2

High-throughput

0.574

High

514481

CBX8
Chromobox protein homolog 8

2

2

High-throughput

0.574

High

394016

A4
Amyloid-beta precursor protein

1

1

Small-scale

0.562

High

315923

NPTXR
Neuronal pentraxin receptor

2

2

High-throughput

0.558

High

514393

CC50B
Cell cycle control protein 50B

2

1

High-throughput

0.553

High

514506

SIGL9
Sialic acid-binding Ig-like lectin 9

2

2

High-throughput

0.553

High

216656

CREB3
Cyclic AMP-responsive element-binding protein 3

1

0

High-throughput

0.549

High

126507

QSOX1
Sulfhydryl oxidase 1

1

1

High-throughput

0.536

High

182252

TPSN
Tapasin

1

1

High-throughput

0.536

High

259493

LRRN2
Leucine-rich repeat neuronal protein 2

1

2

High-throughput

0.536

High

260216

ENTP6
Ectonucleoside triphosphate diphosphohydrolase 6

1

1

High-throughput

0.536

High

276917

ATRN
Attractin

1

1

High-throughput

0.536

High

299552

LRIG2
Leucine-rich repeats and immunoglobulin-like domains protein 2

1

1

High-throughput

0.536

High

337844

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.536

High

341306

FA10
Coagulation factor X

1

5

High-throughput

0.536

High

341484

UROK
Urokinase-type plasminogen activator

1

3

High-throughput

0.536

High

441411

MET
Hepatocyte growth factor receptor

1

5

High-throughput

0.536

High

514334

HLAE
HLA class I histocompatibility antigen, alpha chain E

1

4

High-throughput

0.536

High

514345

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

4

High-throughput

0.536

High

514363

NOMO3
BOS complex subunit NOMO3

1

1

High-throughput

0.536

High

514374

MFGM
Lactadherin

1

4

High-throughput

0.536

High

514376

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

2

High-throughput

0.536

High

514379

DNJC3
DnaJ homolog subfamily C member 3

1

2

High-throughput

0.536

High

514381

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

4

High-throughput

0.536

High

514382

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

4

High-throughput

0.536

High

514383

STIM1
Stromal interaction molecule 1

1

1

High-throughput

0.536

High

514385

DAG1
Dystroglycan 1

1

1

High-throughput

0.536

High

514387

NOMO1
BOS complex subunit NOMO1

1

1

High-throughput

0.536

High

514389

PRSS8
Prostasin

1

3

High-throughput

0.536

High

514392

HFE
Hereditary hemochromatosis protein

1

5

High-throughput

0.536

High

514396

LRC24
Leucine-rich repeat-containing protein 24

1

3

High-throughput

0.536

High

514399

AGRF1
Adhesion G-protein coupled receptor F1

1

3

High-throughput

0.536

High

514400

METRL
Meteorin-like protein

1

1

High-throughput

0.536

High

514449

HMR1
Major histocompatibility complex class I-related gene protein

1

5

High-throughput

0.536

High

514453

P121A
Nuclear envelope pore membrane protein POM 121

1

1

High-throughput

0.536

High

514455

CLP1L
Lipid scramblase CLPTM1L

1

1

High-throughput

0.536

High

514464

CSTN3
Calsyntenin-3

1

1

High-throughput

0.536

High

514470

CNTP3
Contactin-associated protein-like 3

1

4

High-throughput

0.536

High

514473

SEM4C
Semaphorin-4C

1

3

High-throughput

0.536

High

514487

TOR4A
Torsin-4A

1

1

High-throughput

0.536

High

514493

STIM2
Stromal interaction molecule 2

1

1

High-throughput

0.536

High

514501

METRN
Meteorin

1

1

High-throughput

0.536

High

514505

DJC16
DnaJ homolog subfamily C member 16

1

2

High-throughput

0.536

High

514509

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

1

High-throughput

0.536

High

514510

ST14
Suppressor of tumorigenicity 14 protein

1

4

High-throughput

0.536

High

111312

J3KQ12
Seipin

1

1

High-throughput

0.515

High

233048

FZD6
Frizzled-6

1

0

High-throughput

0.513

High

265749

CRLF1
Cytokine receptor-like factor 1

1

0

High-throughput

0.513

High

274911

RENR
Renin receptor

1

0

High-throughput

0.513

High

454679

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

507814

FGFR1
Fibroblast growth factor receptor 1

1

0

High-throughput

0.513

High

514335

PERF
Perforin-1

1

0

High-throughput

0.513

High

514339

AMD
Peptidyl-glycine alpha-amidating monooxygenase

1

0

High-throughput

0.513

High

514341

PGH1
Prostaglandin G/H synthase 1

1

0

High-throughput

0.513

High

514352

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

0

High-throughput

0.513

High

514357

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

0

High-throughput

0.513

High

514358

MMP15
Matrix metalloproteinase-15

1

0

High-throughput

0.513

High

514380

MSLN
Mesothelin

1

0

High-throughput

0.513

High

514386

MBTP1
Membrane-bound transcription factor site-1 protease

1

0

High-throughput

0.513

High

514388

PON2
Serum paraoxonase/arylesterase 2

1

0

High-throughput

0.513

High

514390

MA2A1
Alpha-mannosidase 2

1

0

High-throughput

0.513

High

514391

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

0

High-throughput

0.513

High

514403

MYORG
Myogenesis-regulating glycosidase

1

0

High-throughput

0.513

High

514409

SE6L2
Seizure 6-like protein 2

1

0

High-throughput

0.513

High

514413

C1QL4
Complement C1q-like protein 4

1

0

High-throughput

0.513

High

514414

CILP2
Cartilage intermediate layer protein 2

1

0

High-throughput

0.513

High

514416

GLBL2
Beta-galactosidase-1-like protein 2

1

0

High-throughput

0.513

High

514423

ABD12
Lysophosphatidylserine lipase ABHD12

1

0

High-throughput

0.513

High

514426

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.513

High

514440

RDH11
Retinol dehydrogenase 11

1

0

High-throughput

0.513

High

514456

NAR5
Ecto-ADP-ribosyltransferase 5

1

0

High-throughput

0.513

High

514460

LMF1
Lipase maturation factor 1

1

0

High-throughput

0.513

High

514461

HPLN3
Hyaluronan and proteoglycan link protein 3

1

0

High-throughput

0.513

High

514463

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.513

High

514467

TMM43
Transmembrane protein 43

1

0

High-throughput

0.513

High

514480

MER34
Endogenous retroviral envelope protein HEMO

1

0

High-throughput

0.513

High

514486

P4HTM
Transmembrane prolyl 4-hydroxylase

1

0

High-throughput

0.513

High

514494

FPRP
Prostaglandin F2 receptor negative regulator

1

0

High-throughput

0.513

High

514499

LCAP
Leucyl-cystinyl aminopeptidase

1

0

High-throughput

0.513

High

514354

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

3

Small-scale

0.512

High

58788

T131L
Transmembrane protein 131-like

1

1

High-throughput

0.489

High

152070

TOR1B
Torsin-1B

1

1

High-throughput

0.489

High

152241

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

4

High-throughput

0.489

High

165151

PLXB2
Plexin-B2

1

8

High-throughput

0.489

High

234738

MPZL2
Myelin protein zero-like protein 2

1

1

High-throughput

0.489

High

299621

SUN1
SUN domain-containing protein 1

1

1

High-throughput

0.489

High

330446

CLPT1
Putative lipid scramblase CLPTM1

1

1

High-throughput

0.489

High

355011

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

7

High-throughput

0.489

High

382574

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

6

High-throughput

0.489

High

419143

ITAV
Integrin alpha-V

1

5

High-throughput

0.489

High

435515

IGF1R
Insulin-like growth factor 1 receptor

1

1

High-throughput

0.489

High

443025

ITA5
Integrin alpha-5

1

5

High-throughput

0.489

High

514338

ITA2
Integrin alpha-2

1

5

High-throughput

0.489

High

514340

EPHA1
Ephrin type-A receptor 1

1

1

High-throughput

0.489

High

514342

ITA6
Integrin alpha-6

1

5

High-throughput

0.489

High

514343

ITA3
Integrin alpha-3

1

5

High-throughput

0.489

High

514350

SCNNA
Amiloride-sensitive sodium channel subunit alpha

1

1

High-throughput

0.489

High

514359

PLXA3
Plexin-A3

1

8

High-throughput

0.489

High

514364

ASIC1
Acid-sensing ion channel 1

1

1

High-throughput

0.489

High

514365

CNTP1
Contactin-associated protein 1

1

4

High-throughput

0.489

High

514366

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

7

High-throughput

0.489

High

514368

IDD
Integral membrane protein DGCR2/IDD

1

1

High-throughput

0.489

High

514370

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

2

High-throughput

0.489

High

514371

RON
Macrophage-stimulating protein receptor

1

8

High-throughput

0.489

High

514372

APLP2
Amyloid beta precursor like protein 2

1

1

High-throughput

0.489

High

514384

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

5

High-throughput

0.489

High

514401

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

1

High-throughput

0.489

High

514405

CNNM4
Metal transporter CNNM4

1

2

High-throughput

0.489

High

514411

MEGF8
Multiple epidermal growth factor-like domains protein 8

1

1

High-throughput

0.489

High

514412

GALT5
Polypeptide N-acetylgalactosaminyltransferase 5

1

2

High-throughput

0.489

High

514417

AGRA3
Adhesion G protein-coupled receptor A3

1

3

High-throughput

0.489

High

514429

TTC13
Tetratricopeptide repeat protein 13

1

1

High-throughput

0.489

High

514432

GALT6
Polypeptide N-acetylgalactosaminyltransferase 6

1

2

High-throughput

0.489

High

514433

PHC3
Polyhomeotic-like protein 3

1

2

High-throughput

0.489

High

514434

CNNM3
Metal transporter CNNM3

1

2

High-throughput

0.489

High

514437

CADM4
Cell adhesion molecule 4

1

1

High-throughput

0.489

High

514445

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

1

High-throughput

0.489

High

514446

TM131
Transmembrane protein 131

1

2

High-throughput

0.489

High

514459

DCBD2
Discoidin, CUB and LCCL domain-containing protein 2

1

4

High-throughput

0.489

High

514466

LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3

1

4

High-throughput

0.489

High

514469

TMM59
Transmembrane protein 59

1

1

High-throughput

0.489

High

514474

ADA19
Disintegrin and metalloproteinase domain-containing protein 19

1

4

High-throughput

0.489

High

514477

SEM6B
Semaphorin-6B

1

3

High-throughput

0.489

High

514479

CNNM2
Metal transporter CNNM2

1

2

High-throughput

0.489

High

514484

SEM4G
Semaphorin-4G

1

4

High-throughput

0.489

High

514485

CC50A
Cell cycle control protein 50A

1

1

High-throughput

0.489

High

514489

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.489

High

514492

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

3

High-throughput

0.489

High

514495

CHPF2
Chondroitin sulfate glucuronyltransferase

1

1

High-throughput

0.489

High

514497

SUN2
SUN domain-containing protein 2

1

1

High-throughput

0.489

High

514498

CEIP2
Inactive cell surface hyaluronidase CEMIP2

1

1

High-throughput

0.489

High

514500

PLXA1
Plexin-A1

1

7

High-throughput

0.489

High

514502

TM59L
Transmembrane protein 59-like

1

1

High-throughput

0.489

High

514503

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

1

4

High-throughput

0.489

High

514504

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

1

High-throughput

0.489

High

514508

PLXD1
Plexin-D1

1

8

High-throughput

0.489

High

514511

AGRG1
Adhesion G-protein coupled receptor G1

1

2

High-throughput

0.489

High

514451

BSCL2
Seipin

1

1

High-throughput

0.481

High

514496

DNJB9
DnaJ homolog subfamily B member 9

1

2

Small-scale

0.479

High

514360

TERA
Transitional endoplasmic reticulum ATPase

1

0

Small-scale

0.458

High

125121

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

Small-scale

0.457

High

514475

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

3

Small-scale

0.457

High

354629

HLAH
Putative HLA class I histocompatibility antigen, alpha chain H

1

4

High-throughput

0.445

High

382281

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

4

High-throughput

0.445

High

514418

DJC10
DnaJ homolog subfamily C member 10

1

2

Small-scale

0.437

High

514435

TOIP2
Torsin-1A-interacting protein 2

1

0

High-throughput

0.426

High

69542

B0QXZ6
Chromobox 6

1

2

High-throughput

0.407

High

514458

CNT3B
Contactin-associated protein-like 3B

1

4

High-throughput

0.407

High

514482

SEM4B
Semaphorin-4B

1

4

High-throughput

0.407

High

514465

TMM79
Transmembrane protein 79

6

0

High-throughput

0.387

High

514443

GPX8
Probable glutathione peroxidase 8

3

0

High-throughput

0.346

High

514422

SYNE4
Nesprin-4

2

0

High-throughput

0.343

High

514347

BMI1
Polycomb complex protein BMI-1

2

0

High-throughput

0.328

High

514444

SCRB1
Scavenger receptor class B member 1

2

0

High-throughput

0.328

High

514452

SREC2
Scavenger receptor class F member 2

2

0

High-throughput

0.328

High

131301

CLD5
Claudin-5

2

0

High-throughput

0.316

High

514333

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.316

High

514344

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

2

0

High-throughput

0.316

High

514346

ICAM3
Intercellular adhesion molecule 3

2

0

High-throughput

0.316

High

514355

CXA8
Gap junction alpha-8 protein

2

0

High-throughput

0.316

High

514378

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.316

High

514398

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

514410

CPLX4
Complexin-4

2

0

High-throughput

0.316

High

514415

TM139
Transmembrane protein 139

2

0

High-throughput

0.316

High

514421

LSME2
Leucine-rich single-pass membrane protein 2

2

0

High-throughput

0.316

High

514439

FNDC9
Fibronectin type III domain-containing protein 9

2

0

High-throughput

0.316

High

514442

GP152
Probable G-protein coupled receptor 152

2

0

High-throughput

0.316

High

514472

SMIM3
Small integral membrane protein 3

1

0

High-throughput

0.303

High

514362

SC61G
Protein transport protein Sec61 subunit gamma

1

0

High-throughput

0.299

High

230114

MGRN1
E3 ubiquitin-protein ligase MGRN1

1

0

High-throughput

0.279

Low

236284

B4GT3
Beta-1,4-galactosyltransferase 3

1

0

High-throughput

0.279

Low

295709

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

0

High-throughput

0.279

Low

514348

IDUA
Alpha-L-iduronidase

1

0

High-throughput

0.279

Low

514349

TGFR1
TGF-beta receptor type-1

1

0

High-throughput

0.279

Low

514353

ECE1
Endothelin-converting enzyme 1

1

0

High-throughput

0.279

Low

514356

CD151
CD151 antigen

1

0

High-throughput

0.279

Low

514367

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.279

Low

514369

B4GN1
Beta-1,4 N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.279

Low

514375

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

0

High-throughput

0.279

Low

514377

HYAL2
Hyaluronidase-2

1

0

High-throughput

0.279

Low

514394

SHSL1
Protein shisa-like-1

1

0

High-throughput

0.279

Low

514395

FUT11
Alpha-(1,3)-fucosyltransferase 11

1

0

High-throughput

0.279

Low

514402

SE1L3
Protein sel-1 homolog 3

1

0

High-throughput

0.279

Low

514404

TECT3
Tectonic-3

1

0

High-throughput

0.279

Low

514406

S39A4
Zinc transporter ZIP4

1

0

High-throughput

0.279

Low

514407

I27RA
Interleukin-27 receptor subunit alpha

1

0

High-throughput

0.279

Low

514408

SUSD1
Sushi domain-containing protein 1

1

0

High-throughput

0.279

Low

514420

K2013
Uncharacterized protein KIAA2013

1

0

High-throughput

0.279

Low

514424

LARG2
Xylosyl- and glucuronyltransferase LARGE2

1

0

High-throughput

0.279

Low

514425

KCD17
BTB/POZ domain-containing protein KCTD17

1

0

High-throughput

0.279

Low

514428

TM87A
Transmembrane protein 87A

1

0

High-throughput

0.279

Low

514430

UXS1
UDP-glucuronic acid decarboxylase 1

1

0

High-throughput

0.279

Low

514431

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.279

Low

514436

NLGN2
Neuroligin-2

1

0

High-throughput

0.279

Low

514438

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.279

Low

514447

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.279

Low

514448

EXT2
Exostosin-2

1

0

High-throughput

0.279

Low

514450

TTC17
Tetratricopeptide repeat protein 17

1

0

High-throughput

0.279

Low

514457

H6ST2
Heparan-sulfate 6-O-sulfotransferase 2

1

0

High-throughput

0.279

Low

514462

TM9S2
Transmembrane 9 superfamily member 2

1

0

High-throughput

0.279

Low

514471

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.279

Low

514476

F234A
Protein FAM234A

1

0

High-throughput

0.279

Low

514483

CHSTC
Carbohydrate sulfotransferase 12

1

0

High-throughput

0.279

Low

514488

CA2D2
Voltage-dependent calcium channel subunit alpha-2/delta-2

1

0

High-throughput

0.279

Low

514490

CELR1
Cadherin EGF LAG seven-pass G-type receptor 1

1

0

High-throughput

0.279

Low

514507

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

0

High-throughput

0.279

Low

241855

PQBP1
Polyglutamine-binding protein 1

1

0

Small-scale

0.261

Low

359604

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

514478

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024