Protein: LYOX
Protein-lysine 6-oxidase (EC 1.4.3.13) (Lysyl oxidase) [Cleaved into: Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form]

Gene: LYOX, LOX
Organism: Homo sapiens
Interactions: 62
UniProt ID: P28300

Gene Ontology (top 5):
GO:0001649 - osteoblast differentiation
GO:0001932 - regulation of protein phosphorylation
GO:0004720 - protein-lysine 6-oxidase activity
GO:0005507 - copper ion binding
GO:0005518 - collagen binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

548780

ELN
Elastin

3

5

Small-scale

0.670

High

362851

FINC
Fibronectin

3

6

Small-scale

0.661

High

657693

LOXL2
Lysyl oxidase homolog 2

1

2

Small-scale

0.647

High

327954

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

2

9

Small-scale

0.646

High

657662

FBN1
Fibrillin-1 [Cleaved into: Asprosin]

2

6

Small-scale

0.624

High

373729

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

1

Small-scale

0.595

High

483615

CSH1
Chorionic somatomammotropin hormone 1

1

5

Small-scale

0.586

High

483627

CSH2
Chorionic somatomammotropin hormone 2

1

5

Small-scale

0.586

High

657689

FBLN5
Fibulin-5

2

9

Small-scale

0.576

High

351134

EGF
Pro-epidermal growth factor

1

3

Small-scale

0.536

High

362455

C1QA
Complement C1q subcomponent subunit A

1

2

High-throughput

0.536

High

657663

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.536

High

341361

PLMN
Plasminogen

1

0

Small-scale

0.513

High

657670

DERM
Dermatopontin

1

0

Small-scale

0.513

High

351690

PRL
Prolactin

1

5

Small-scale

0.501

High

351720

SOMA
Somatotropin

1

5

Small-scale

0.501

High

439228

MMP2
72 kDa type IV collagenase

1

5

Small-scale

0.501

High

517925

CO6A1

1

1

Small-scale

0.501

High

602803

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

3

Small-scale

0.501

High

657674

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

8

Small-scale

0.501

High

657677

H2B2E
Histone H2B type 2-E

1

2

Small-scale

0.501

High

501725

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.489

High

657675

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

1

High-throughput

0.489

High

657685

ANTR1
Anthrax toxin receptor 1

1

0

Small-scale

0.480

High

483749

HS71A
Heat shock 70 kDa protein 1A

1

4

Small-scale

0.479

High

595973

EFNA1
Ephrin-A1

1

4

High-throughput

0.479

High

657666

EFNA4
Ephrin-A4

1

4

High-throughput

0.479

High

657668

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

4

Small-scale

0.479

High

282405

STC2
Stanniocalcin-2

1

0

Small-scale

0.458

High

397093

PAI1
Plasminogen activator inhibitor 1

1

0

Small-scale

0.458

High

657669

H11
Histone H1.1

1

2

Small-scale

0.457

High

358482

CO1A1
Collagen alpha-1(I) chain

1

2

Small-scale

0.457

High

358633

CO3A1

1

2

Small-scale

0.457

High

436014

CO1A2
Collagen alpha-2(I) chain

1

2

Small-scale

0.457

High

657679

ATL4
ADAMTS-like protein 4

1

4

Small-scale

0.457

High

345999

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.445

High

657691

PA2G4
Proliferation-associated protein 2G4

1

0

Small-scale

0.438

High

205075

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

308427

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.437

High

610241

CBL
E3 ubiquitin-protein ligase CBL

1

1

Small-scale

0.437

High

657665

EFNA3
Ephrin-A3

1

4

High-throughput

0.437

High

657667

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

657684

SH3K1
SH3 domain-containing kinase-binding protein 1

1

1

Small-scale

0.437

High

657694

CD2AP
CD2-associated protein

1

1

Small-scale

0.437

High

657681

P66B
Transcriptional repressor p66-beta

1

2

Small-scale

0.417

High

657682

AP2C
Transcription factor AP-2 gamma

1

2

High-throughput

0.417

High

657676

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

0

Small-scale

0.305

High

59115

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.279

Low

118841

GTPB1
GTP-binding protein 1

1

0

High-throughput

0.279

Low

649036

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

0

High-throughput

0.279

Low

657672

PDE7A
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A

1

0

High-throughput

0.279

Low

657678

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

1

0

High-throughput

0.279

Low

657683

N42L2
NEDD4-binding protein 2-like 2

1

0

High-throughput

0.279

Low

657686

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

0

High-throughput

0.279

Low

657687

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.279

Low

657690

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.279

Low

657680

DHDDS
Dehydrodolichyl diphosphate synthase complex subunit DHDDS

1

0

Small-scale

0.265

Low

657664

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.261

Low

657671

SOS2
Son of sevenless homolog 2

1

0

Small-scale

0.238

Low

657673

MDC1
Mediator of DNA damage checkpoint protein 1

1

0

Small-scale

0.238

Low

657688

UXT
Protein UXT

1

0

Small-scale

0.238

Low

657692

MEMO1
Protein MEMO1

1

0

Small-scale

0.238

Low


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Last updated: 15 Jul 2024