Protein: KGD4
Alpha-ketoglutarate dehydrogenase component 4 (Alpha-ketoglutarate dehydrogenase subunit 4)

Gene: KGD4
Organism: Homo sapiens
Interactions: 100
UniProt ID: P82909

Gene Ontology (top 5):
GO:0004591 - oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006099 - tricarboxylic acid cycle
GO:0006103 - 2-oxoglutarate metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

452738

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

5

0

High-throughput

0.684

High

947830

HSC20
Iron-sulfur cluster co-chaperone protein HscB

2

0

High-throughput

0.585

High

262786

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

947810

GRSF1
G-rich sequence factor 1

2

0

High-throughput

0.559

High

947818

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

505960

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

1

High-throughput

0.536

High

739071

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.536

High

947805

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

2

High-throughput

0.536

High

947870

OGDHL
2-oxoglutarate dehydrogenase-like, mitochondrial

1

2

High-throughput

0.536

High

729212

HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial

1

0

High-throughput

0.513

High

947833

TCAIM
T-cell activation inhibitor, mitochondrial

1

0

High-throughput

0.513

High

264887

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

270018

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

440461

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

2

High-throughput

0.479

High

803088

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.479

High

947809

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

947814

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

3

High-throughput

0.479

High

947822

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

1

High-throughput

0.479

High

947827

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

3

High-throughput

0.479

High

947835

MCU
Calcium uniporter protein, mitochondrial

1

1

High-throughput

0.479

High

947838

FAKD4
FAST kinase domain-containing protein 4

1

3

High-throughput

0.479

High

947840

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.479

High

947845

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

947856

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

947864

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

1

High-throughput

0.479

High

947866

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

3

High-throughput

0.479

High

947869

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

59159

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

63335

MET15
12S rRNA N4-methylcytidine

1

0

High-throughput

0.458

High

173012

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

276816

SCO1
Protein SCO1 homolog, mitochondrial

1

0

High-throughput

0.458

High

327409

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

336865

OTC
Ornithine transcarbamylase, mitochondrial

1

0

High-throughput

0.458

High

486507

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

499685

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

737304

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

777535

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

789743

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

799202

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

827336

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

947804

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

947806

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

947807

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

947811

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

947812

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

947813

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.458

High

947815

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

947816

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

947819

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

947821

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

947825

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

947826

DHX30
ATP-dependent RNA helicase DHX30

1

0

High-throughput

0.458

High

947839

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

947841

FMT
Methionyl-tRNA formyltransferase, mitochondrial

1

0

High-throughput

0.458

High

947842

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

947843

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

947844

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.458

High

947846

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.458

High

947847

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

947848

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.458

High

947849

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

947850

TR61B
tRNA

1

0

High-throughput

0.458

High

947851

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

947852

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

947853

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

947854

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.458

High

947855

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

947857

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.458

High

947859

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

947862

NGRN
Neugrin

1

0

High-throughput

0.458

High

947863

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

947865

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

947867

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

947871

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

947873

DJC15
DnaJ homolog subfamily C member 15

1

0

High-throughput

0.458

High

947837

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

1

High-throughput

0.437

High

947831

GT252
Procollagen galactosyltransferase 2

2

0

High-throughput

0.328

High

164601

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

0

High-throughput

0.279

Low

676861

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.279

Low

864941

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.279

Low

947829

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

0

High-throughput

0.279

Low

947832

THEM5
Acyl-coenzyme A thioesterase THEM5

1

0

High-throughput

0.279

Low

947868

HDAC6
Histone deacetylase 6

1

0

High-throughput

0.279

Low

338275

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.249

Low

434825

CXB1
Gap junction beta-1 protein

1

0

Small-scale

0.249

Low

813379

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.249

Low

815226

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.249

Low

947803

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.249

Low

947808

QOR
Quinone oxidoreductase

1

0

High-throughput

0.249

Low

947817

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low

947823

CH082
UPF0598 protein C8orf82

1

0

High-throughput

0.249

Low

947824

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

947828

SLN11
Schlafen family member 11

1

0

High-throughput

0.249

Low

947836

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.249

Low

947858

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.249

Low

947860

TM165
Putative divalent cation/proton antiporter TMEM165

1

0

High-throughput

0.249

Low

947872

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.249

Low

947820

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.232

Low

947834

POC5
Centrosomal protein POC5

1

0

High-throughput

0.232

Low

947861

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024