Protein: ACOT1
Acyl-coenzyme A thioesterase 1 (Acyl-CoA thioesterase 1) (EC 3.1.2.-) (CTE-I) (CTE-Ib) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase) (Palmitoyl-coenzyme A thioesterase) (EC 3.1.2.2)

Gene: ACOT1
Organism: Homo sapiens
Interactions: 108
UniProt ID: Q86TX2

Gene Ontology (top 5):
GO:0000038 - very long-chain fatty acid metabolic process
GO:0001676 - long-chain fatty acid metabolic process
GO:0005829 - cytosol
GO:0006631 - fatty acid metabolic process
GO:0006637 - acyl-CoA metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

833085

ACOT2
Acyl-coenzyme A thioesterase 2, mitochondrial

2

0

High-throughput

0.770

High

1198854

HSC20
Iron-sulfur cluster co-chaperone protein HscB

2

0

High-throughput

0.585

High

325256

AIFM1
Apoptosis-inducing factor 1, mitochondrial

2

1

High-throughput

0.584

High

525550

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

2

0

High-throughput

0.559

High

262877

CISY
Citrate synthase, mitochondrial

2

1

High-throughput

0.533

High

1017947

GRSF1
G-rich sequence factor 1

2

1

High-throughput

0.533

High

451921

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

1

High-throughput

0.489

High

374465

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

499884

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.479

High

737394

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.479

High

777626

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

827462

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.479

High

900643

RHOA
Transforming protein RhoA

1

2

High-throughput

0.479

High

951121

RHOG
Rho-related GTP-binding protein RhoG

1

2

High-throughput

0.479

High

958958

TFAM
Transcription factor A, mitochondrial

1

1

High-throughput

0.479

High

990155

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.479

High

994501

QOR
Quinone oxidoreductase

1

1

High-throughput

0.479

High

1183923

DHX30
ATP-dependent RNA helicase DHX30

1

1

High-throughput

0.479

High

1198856

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

3

High-throughput

0.479

High

1198859

CHCH1
Small ribosomal subunit protein mS37

1

1

High-throughput

0.479

High

1198862

FMT
Methionyl-tRNA formyltransferase, mitochondrial

1

1

High-throughput

0.479

High

1198864

MTEF3
Transcription termination factor 3, mitochondrial

1

2

High-throughput

0.479

High

1198874

TACO1
Translational activator of cytochrome c oxidase 1

1

1

High-throughput

0.479

High

1198882

IF3M
Translation initiation factor IF-3, mitochondrial

1

1

High-throughput

0.479

High

1198887

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

1

High-throughput

0.479

High

1198889

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

1

1

High-throughput

0.470

High

227928

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

932233

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

1036698

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1198865

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

0

High-throughput

0.458

High

1198898

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

59219

VWA8
von Willebrand factor A domain-containing protein 8

1

1

High-throughput

0.437

High

63387

MET15
12S rRNA N4-methylcytidine

1

1

High-throughput

0.437

High

173058

RT12
Small ribosomal subunit protein uS12m

1

1

High-throughput

0.437

High

264952

MPPB
Mitochondrial-processing peptidase subunit beta

1

3

High-throughput

0.437

High

270068

RF1M
Peptide chain release factor 1, mitochondrial

1

5

High-throughput

0.437

High

276848

SCO1
Protein SCO1 homolog, mitochondrial

1

1

High-throughput

0.437

High

327485

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

1

High-throughput

0.437

High

336882

OTC
Ornithine transcarbamylase, mitochondrial

1

1

High-throughput

0.437

High

385093

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.437

High

440602

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.437

High

486565

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

1

High-throughput

0.437

High

609389

FGFR3
Fibroblast growth factor receptor 3

1

9

High-throughput

0.437

High

789869

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.437

High

799276

EFTS
Elongation factor Ts, mitochondrial

1

1

High-throughput

0.437

High

803154

IF2M
Translation initiation factor IF-2, mitochondrial

1

3

High-throughput

0.437

High

981315

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

High-throughput

0.437

High

1014416

MPPA
Mitochondrial-processing peptidase subunit alpha

1

3

High-throughput

0.437

High

1020478

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

High-throughput

0.437

High

1045793

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.437

High

1051001

ICT1
Large ribosomal subunit protein mL62

1

1

High-throughput

0.437

High

1062242

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

7

High-throughput

0.437

High

1068005

PDK1
[Pyruvate dehydrogenase

1

1

High-throughput

0.437

High

1074613

SURF1
Surfeit locus protein 1

1

1

High-throughput

0.437

High

1128173

SYAM
Alanine--tRNA ligase, mitochondrial

1

1

High-throughput

0.437

High

1152884

MRM1
rRNA methyltransferase 1, mitochondrial

1

1

High-throughput

0.437

High

1157937

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

3

High-throughput

0.437

High

1158820

CH082
UPF0598 protein C8orf82

1

1

High-throughput

0.437

High

1170623

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1183166

COX15
Heme A synthase COX15

1

1

High-throughput

0.437

High

1185304

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

7

High-throughput

0.437

High

1198855

MCU
Calcium uniporter protein, mitochondrial

1

3

High-throughput

0.437

High

1198857

FAKD4
FAST kinase domain-containing protein 4

1

7

High-throughput

0.437

High

1198858

MCUR1
Mitochondrial calcium uniporter regulator 1

1

3

High-throughput

0.437

High

1198860

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

3

High-throughput

0.437

High

1198863

RRFM
Ribosome-recycling factor, mitochondrial

1

1

High-throughput

0.437

High

1198867

RCC1L
RCC1-like G exchanging factor-like protein

1

1

High-throughput

0.437

High

1198869

IMP1L
Mitochondrial inner membrane protease subunit 1

1

2

High-throughput

0.437

High

1198870

TEFM
Transcription elongation factor, mitochondrial

1

1

High-throughput

0.437

High

1198871

EFGM
Elongation factor G, mitochondrial

1

3

High-throughput

0.437

High

1198872

IMP2L
Mitochondrial inner membrane protease subunit 2

1

2

High-throughput

0.437

High

1198875

CQ080
Mitochondrial nucleoid-associated protein 1

1

1

High-throughput

0.437

High

1198876

TMM70
Transmembrane protein 70, mitochondrial

1

1

High-throughput

0.437

High

1198877

TR61B
tRNA

1

1

High-throughput

0.437

High

1198878

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

1

High-throughput

0.437

High

1198879

RT26
Small ribosomal subunit protein mS26

1

1

High-throughput

0.437

High

1198880

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

1

High-throughput

0.437

High

1198881

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

3

High-throughput

0.437

High

1198884

MTRFR
Mitochondrial translation release factor in rescue

1

5

High-throughput

0.437

High

1198885

MTG2
Mitochondrial ribosome-associated GTPase 2

1

1

High-throughput

0.437

High

1198886

MET17
Ribosome assembly protein METTL17, mitochondrial

1

1

High-throughput

0.437

High

1198888

SFXN1
Sideroflexin-1

1

1

High-throughput

0.437

High

1198891

NGRN
Neugrin

1

1

High-throughput

0.437

High

1198892

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.437

High

1198893

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

3

High-throughput

0.437

High

1198894

AKIP
Small ribosomal subunit protein mS38

1

1

High-throughput

0.437

High

1198895

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

7

High-throughput

0.437

High

1198896

MRES1
Mitochondrial transcription rescue factor 1

1

1

High-throughput

0.437

High

1198897

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

5

High-throughput

0.437

High

1198902

RM11
Large ribosomal subunit protein uL11m

1

1

High-throughput

0.437

High

403663

AP2A
Transcription factor AP-2-alpha

3

0

High-throughput

0.345

High

882937

RBM11
Splicing regulator RBM11

1

0

High-throughput

0.282

High

1198868

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.282

High

517341

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.279

Low

1081667

KCA10
Potassium voltage-gated channel subfamily A member 10

1

0

High-throughput

0.279

Low

1198873

S35A5
UDP-sugar transporter protein SLC35A5

1

0

High-throughput

0.279

Low

1198899

ZF69B
Zinc finger protein 69 homolog B

1

0

High-throughput

0.279

Low

1198900

TM11E
Transmembrane protease serine 11E

1

0

High-throughput

0.279

Low

1198901

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

0

High-throughput

0.279

Low

1198890

HHATL
Protein-cysteine N-palmitoyltransferase HHAT-like protein

1

0

High-throughput

0.269

Low

553077

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

651582

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

720819

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

751705

GRP75
Stress-70 protein, mitochondrial

1

0

High-throughput

0.249

Low

1086640

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1198861

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

High-throughput

0.249

Low

1198866

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.249

Low

1198883

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024