Protein: HSPB8
Heat shock protein beta-8 (HspB8) (Alpha-crystallin C chain) (E2-induced gene 1 protein) (Heat shock protein family B member 8) (Protein kinase H11) (Small stress protein-like protein HSP22)

Gene: HSPB8
Organism: Homo sapiens
Interactions: 164
UniProt ID: Q9UJY1

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0034620 - cellular response to unfolded protein

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1354468

HSPB7
Heat shock protein beta-7

5

18

Small-scale

0.941

High

388788

HSPB1
Heat shock protein beta-1

3

16

Small-scale

0.839

High

1356175

HSPB8
Heat shock protein beta-8

2

19

Small-scale

0.825

High

1080914

HSPB2
Heat shock protein beta-2

2

16

Small-scale

0.817

High

324673

BAG3
BAG family molecular chaperone regulator 3

13

9

Small-scale

0.762

High

147854

HSPB6
Heat shock protein beta-6

1

15

Small-scale

0.713

High

359087

CRYAB
Alpha-crystallin B chain

1

16

Small-scale

0.713

High

1102967

QRIC1
Transcriptional regulator QRICH1

4

8

High-throughput

0.704

High

59348

VWA8
von Willebrand factor A domain-containing protein 8

3

1

High-throughput

0.675

High

847923

BRCA2
Breast cancer type 2 susceptibility protein

3

1

High-throughput

0.675

High

1309702

NUD12
NAD-capped RNA hydrolase NUDT12

3

6

High-throughput

0.675

High

1078370

MLF2
Myeloid leukemia factor 2

3

3

High-throughput

0.669

High

1264767

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

3

4

High-throughput

0.667

High

1022271

HSPB3
Heat shock protein beta-3

1

18

Small-scale

0.656

High

610190

RFX1
MHC class II regulatory factor RFX1

2

2

High-throughput

0.628

High

984462

EF1A2
Elongation factor 1-alpha 2

2

1

High-throughput

0.628

High

1092971

LONF2
LON peptidase N-terminal domain and RING finger protein 2

2

7

High-throughput

0.628

High

1170161

FA83H
Protein FAM83H

2

3

High-throughput

0.628

High

1173782

ACD11
Acyl-CoA dehydrogenase family member 11

2

2

High-throughput

0.628

High

1253163

WDR20
WD repeat-containing protein 20

2

4

High-throughput

0.628

High

1254017

ALMS1
Centrosome-associated protein ALMS1

2

6

High-throughput

0.628

High

1317589

SETD2
Histone-lysine N-methyltransferase SETD2

2

3

High-throughput

0.628

High

146700

SOCS7
Suppressor of cytokine signaling 7

2

2

High-throughput

0.606

High

276612

TPC6A
Trafficking protein particle complex subunit 6A

2

2

High-throughput

0.606

High

1061746

Q149M6
Exophilin 5

3

1

High-throughput

0.585

High

825349

RPIA
Ribose-5-phosphate isomerase

2

0

High-throughput

0.580

High

1184803

ATOSB
Atos homolog protein B

2

0

High-throughput

0.580

High

1356179

DUS12
Dual specificity protein phosphatase 12

1

6

High-throughput

0.573

High

1243583

EXPH5
Exophilin-5

3

1

High-throughput

0.558

High

1217920

MISP
Mitotic interactor and substrate of PLK1

2

1

High-throughput

0.553

High

147830

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

3

High-throughput

0.536

High

150399

ZN195
Zinc finger protein 195

1

2

High-throughput

0.536

High

152812

RGPD8
RANBP2-like and GRIP domain-containing protein 8

1

2

High-throughput

0.536

High

152915

APAF
Apoptotic protease-activating factor 1

1

4

High-throughput

0.536

High

164031

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

4

High-throughput

0.536

High

164154

ARHGA
Rho guanine nucleotide exchange factor 10

1

4

High-throughput

0.536

High

165099

SC16A
Protein transport protein Sec16A

1

2

High-throughput

0.536

High

175936

P73
Tumor protein p73

1

5

High-throughput

0.536

High

257113

DJC13
DnaJ homolog subfamily C member 13

1

2

High-throughput

0.536

High

259314

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

1

High-throughput

0.536

High

283058

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

4

High-throughput

0.536

High

299744

SUN1
SUN domain-containing protein 1

1

1

High-throughput

0.536

High

417544

PYGL
Glycogen phosphorylase, liver form

1

2

High-throughput

0.536

High

419076

TPM3
Tropomyosin alpha-3 chain

1

5

High-throughput

0.536

High

434446

TPM2
Tropomyosin beta chain

1

6

High-throughput

0.536

High

451328

TPM1
Tropomyosin alpha-1 chain

1

5

High-throughput

0.536

High

502931

MYH3
Myosin-3

1

9

High-throughput

0.536

High

506216

PYGB
Glycogen phosphorylase, brain form

1

2

High-throughput

0.536

High

506277

PYGM
Glycogen phosphorylase, muscle form

1

2

High-throughput

0.536

High

522580

MYH1
Myosin-1

1

9

High-throughput

0.536

High

528397

MYH6
Myosin-6

1

9

High-throughput

0.536

High

528430

MYH8
Myosin-8

1

9

High-throughput

0.536

High

534039

ENOB
Beta-enolase

1

2

High-throughput

0.536

High

616885

JAK1
Tyrosine-protein kinase JAK1

1

8

High-throughput

0.536

High

658451

DPOD1
DNA polymerase delta catalytic subunit

1

2

High-throughput

0.536

High

686772

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.536

High

725711

ACTN2
Alpha-actinin-2

1

8

High-throughput

0.536

High

728967

AHR
Aryl hydrocarbon receptor

1

4

High-throughput

0.536

High

781241

ETV3
ETS translocation variant 3

1

4

High-throughput

0.536

High

807875

MAP1B
Microtubule-associated protein 1B

1

7

High-throughput

0.536

High

839217

EMD
Emerin

1

1

High-throughput

0.536

High

840426

ERF
ETS domain-containing transcription factor ERF

1

4

High-throughput

0.536

High

850229

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.536

High

855756

KIF11
Kinesin-like protein KIF11

1

1

High-throughput

0.536

High

885626

MLF1
Myeloid leukemia factor 1

1

3

High-throughput

0.536

High

964279

FOXK2
Forkhead box protein K2

1

3

High-throughput

0.536

High

977981

ZNF92
Zinc finger protein 92

1

1

High-throughput

0.536

High

992325

DPOE1
DNA polymerase epsilon catalytic subunit A

1

2

High-throughput

0.536

High

1024846

DUS4
Dual specificity protein phosphatase 4

1

6

High-throughput

0.536

High

1035151

MYO9B
Unconventional myosin-IXb

1

12

High-throughput

0.536

High

1038333

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

5

High-throughput

0.536

High

1038942

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

2

High-throughput

0.536

High

1040066

IQGA2
Ras GTPase-activating-like protein IQGAP2

1

4

High-throughput

0.536

High

1044815

RIN1
Ras and Rab interactor 1

1

2

High-throughput

0.536

High

1109730

RGL3
Ral guanine nucleotide dissociation stimulator-like 3

1

2

High-throughput

0.536

High

1114256

TBB8
Tubulin beta-8 chain

1

2

High-throughput

0.536

High

1122384

WDR81
WD repeat-containing protein 81

1

3

High-throughput

0.536

High

1123340

PKHG4
Puratrophin-1

1

4

High-throughput

0.536

High

1129918

DCA10
DDB1- and CUL4-associated factor 10

1

4

High-throughput

0.536

High

1144808

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

7

High-throughput

0.536

High

1161755

KLD10
Kelch domain-containing protein 10

1

2

High-throughput

0.536

High

1163900

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.536

High

1173889

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

1

3

High-throughput

0.536

High

1175237

TBA1A
Tubulin alpha-1A chain

1

4

High-throughput

0.536

High

1230062

RPTOR
Regulatory-associated protein of mTOR

1

4

High-throughput

0.536

High

1232221

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

2

High-throughput

0.536

High

1261225

CTF18
Chromosome transmission fidelity protein 18 homolog

1

3

High-throughput

0.536

High

1262763

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

8

High-throughput

0.536

High

1264819

TITIN
Titin

1

10

High-throughput

0.536

High

1283222

MYL11
Myosin regulatory light chain 11

1

4

High-throughput

0.536

High

1285487

NACC2
Nucleus accumbens-associated protein 2

1

9

High-throughput

0.536

High

1293198

TONSL
Tonsoku-like protein

1

2

High-throughput

0.536

High

1296437

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

6

High-throughput

0.536

High

1301491

GCP6
Gamma-tubulin complex component 6

1

1

High-throughput

0.536

High

1301584

TRIB1
Tribbles homolog 1

1

7

High-throughput

0.536

High

1305513

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

2

High-throughput

0.536

High

1306176

NPAS1
Neuronal PAS domain-containing protein 1

1

4

High-throughput

0.536

High

1307402

PKP2
Plakophilin-2

1

6

High-throughput

0.536

High

1315201

OSB10
Oxysterol-binding protein-related protein 10

1

3

High-throughput

0.536

High

1330818

SAV1
Protein salvador homolog 1

1

9

High-throughput

0.536

High

1332486

ESRP2
Epithelial splicing regulatory protein 2

1

7

High-throughput

0.536

High

1335311

IF122
Intraflagellar transport protein 122 homolog

1

5

High-throughput

0.536

High

1335867

ZBT20
Zinc finger and BTB domain-containing protein 20

1

4

High-throughput

0.536

High

1336494

SYF1
Pre-mRNA-splicing factor SYF1

1

3

High-throughput

0.536

High

1343263

TF7L2
Transcription factor 7-like 2

1

3

High-throughput

0.536

High

1344049

PDLI7
PDZ and LIM domain protein 7

1

5

High-throughput

0.536

High

1345903

ZCHC3
Zinc finger CCHC domain-containing protein 3

1

1

High-throughput

0.536

High

1356177

MYH2
Myosin-2

1

9

High-throughput

0.536

High

1356178

AKP8L
A-kinase anchor protein 8-like

1

2

High-throughput

0.536

High

1356180

TBD2B
TBC1 domain family member 2B

1

3

High-throughput

0.536

High

1356181

CD11A
Cyclin-dependent kinase 11A

1

1

High-throughput

0.536

High

1356185

IRAK3
Interleukin-1 receptor-associated kinase 3

1

1

High-throughput

0.536

High

1356186

MYH4
Myosin-4

1

9

High-throughput

0.536

High

1356187

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

1

High-throughput

0.536

High

300979

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.513

High

409481

MYL1
Myosin light chain 1/3, skeletal muscle isoform

1

0

High-throughput

0.513

High

1046809

TF2H2
General transcription factor IIH subunit 2

1

0

High-throughput

0.513

High

1068433

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.513

High

1077818

NAB2
NGFI-A-binding protein 2

1

0

High-throughput

0.513

High

1161345

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

1

0

High-throughput

0.513

High

1205293

DAAF5
Dynein axonemal assembly factor 5

1

0

High-throughput

0.513

High

1245347

KNL1
Kinetochore scaffold 1

1

0

High-throughput

0.513

High

1291387

CPNE2
Copine-2

1

0

High-throughput

0.513

High

1318422

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1349144

TF2L1
Transcription factor CP2-like protein 1

1

0

High-throughput

0.513

High

1356144

APC5
Anaphase-promoting complex subunit 5

1

0

High-throughput

0.513

High

1356176

AKA11
A-kinase anchor protein 11

1

0

High-throughput

0.513

High

742596

SYUA
Alpha-synuclein

1

4

Small-scale

0.501

High

561709

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

4

High-throughput

0.489

High

1150570

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

1

High-throughput

0.489

High

1191894

FRMD5
FERM domain-containing protein 5

1

4

High-throughput

0.489

High

1193240

ZER1
Protein zer-1 homolog

1

1

High-throughput

0.489

High

1231207

KLH34
Kelch-like protein 34

1

3

High-throughput

0.489

High

1284665

VP33A
Vacuolar protein sorting-associated protein 33A

1

1

High-throughput

0.489

High

1301613

IF140
Intraflagellar transport protein 140 homolog

1

3

High-throughput

0.489

High

163440

XPO1
Exportin-1

1

5

High-throughput

0.479

High

309140

KI20A
Kinesin-like protein KIF20A

1

5

High-throughput

0.479

High

348187

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.479

High

370669

ESR1
Estrogen receptor

1

5

Small-scale

0.479

High

669056

PML
Protein PML

1

7

High-throughput

0.479

High

877941

FOXA1
Hepatocyte nuclear factor 3-alpha

1

2

High-throughput

0.479

High

923274

RL11
Large ribosomal subunit protein uL5

1

2

Small-scale

0.479

High

1044251

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

5

High-throughput

0.479

High

1120594

Q53FC7
Heat shock 70kDa protein 6

1

4

High-throughput

0.479

High

1292281

AURKB
Aurora kinase B

1

6

High-throughput

0.479

High

1309718

E2AK1
Eukaryotic translation initiation factor 2-alpha kinase 1

1

7

Small-scale

0.479

High

1335695

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

2

Small-scale

0.479

High

1356182

NOD1
Nucleotide-binding oligomerization domain-containing protein 1

1

2

Small-scale

0.479

High

1356184

ASB4
Ankyrin repeat and SOCS box protein 4

1

8

High-throughput

0.479

High

258240

DNJB6
DnaJ homolog subfamily B member 6

1

0

Small-scale

0.458

High

529884

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.445

High

789191

HELZ
Probable helicase with zinc finger domain

1

0

High-throughput

0.426

High

177129

MOT6
Monocarboxylate transporter 6

2

0

High-throughput

0.316

High

1122055

CTSRT
Cation channel sperm-associated targeting subunit tau

2

0

High-throughput

0.316

High

365333

STAT
Statherin

1

0

High-throughput

0.279

Low

1056559

BLTP2
Bridge-like lipid transfer protein family member 2

1

0

High-throughput

0.279

Low

1162137

RHDF2
Inactive rhomboid protein 2

1

0

High-throughput

0.279

Low

1220497

DJC10
DnaJ homolog subfamily C member 10

1

0

High-throughput

0.279

Low

1224022

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

1329135

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

0

High-throughput

0.279

Low

1346152

ABCF3
ATP-binding cassette sub-family F member 3

1

0

High-throughput

0.279

Low

1356183

DLGP4
Disks large-associated protein 4

1

0

High-throughput

0.279

Low

1134047

AT7L2
Ataxin-7-like protein 2

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024