Protein: IGF2
Insulin-like growth factor II (IGF-II) (Somatomedin-A) (T3M-11-derived growth factor) [Cleaved into: Insulin-like growth factor II; Insulin-like growth factor II Ala-25 Del; Preptin]

Gene: IGF2
Organism: Homo sapiens
Interactions: 38
UniProt ID: P01344

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001649 - osteoblast differentiation
GO:0001701 - in utero embryonic development
GO:0001892 - embryonic placenta development
GO:0005158 - insulin receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

352346

IBP3
Insulin-like growth factor-binding protein 3

5

10

Small-scale

0.919

High

352343

IBP1
Insulin-like growth factor-binding protein 1

4

13

Small-scale

0.902

High

352342

IGF1R
Insulin-like growth factor 1 receptor

3

4

High-throughput

0.852

High

352348

IBP4
Insulin-like growth factor-binding protein 4

3

10

Small-scale

0.849

High

352349

IBP6
Insulin-like growth factor-binding protein 6

2

10

Small-scale

0.799

High

352350

IBP5
Insulin-like growth factor-binding protein 5

2

10

Small-scale

0.799

High

352340

INSR
Insulin receptor

2

4

High-throughput

0.789

High

352344

MPRI
Cation-independent mannose-6-phosphate receptor

3

0

Small-scale

0.724

High

352347

IBP2
Insulin-like growth factor-binding protein 2

1

10

High-throughput

0.691

High

352345

IDE
Insulin-degrading enzyme

1

2

Small-scale

0.647

High

352352

CCN3
CCN family member 3

1

2

Small-scale

0.647

High

352354

IBP7
Insulin-like growth factor-binding protein 7

1

3

Small-scale

0.647

High

267208

CLN5
Bis(monoacylglycero)phosphate synthase CLN5

2

1

High-throughput

0.553

High

352360

GP152
Probable G-protein coupled receptor 152

2

1

High-throughput

0.553

High

60266

POTEF
POTE ankyrin domain family member F

1

0

High-throughput

0.513

High

216132

CALU
Calumenin

1

0

High-throughput

0.513

High

352363

ANM6
Protein arginine N-methyltransferase 6

1

0

High-throughput

0.513

High

352369

SUFU
Suppressor of fused homolog

1

0

High-throughput

0.513

High

352338

TRFE
Serotransferrin

1

1

Small-scale

0.501

High

352341

PGS2
Decorin

1

2

Small-scale

0.501

High

352355

RN123
E3 ubiquitin-protein ligase RNF123

1

3

High-throughput

0.489

High

352358

UBR1
E3 ubiquitin-protein ligase UBR1

1

3

High-throughput

0.489

High

352359

UBR2
E3 ubiquitin-protein ligase UBR2

1

3

High-throughput

0.489

High

352364

UBAC1
Ubiquitin-associated domain-containing protein 1

1

1

High-throughput

0.489

High

352339

VTNC
Vitronectin

1

0

Small-scale

0.480

High

352370

FAF1
FAS-associated factor 1

1

2

High-throughput

0.464

High

352356

PCSK4
Proprotein convertase subtilisin/kexin type 4

1

1

Small-scale

0.457

High

352357

CREL2
Protein disulfide isomerase CRELD2

1

1

High-throughput

0.457

High

352351

BAG6
Large proline-rich protein BAG6

1

1

High-throughput

0.439

High

352362

TRI63
E3 ubiquitin-protein ligase TRIM63

1

3

High-throughput

0.439

High

352365

TRI55
Tripartite motif-containing protein 55

1

3

High-throughput

0.439

High

352361

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.299

High

195670

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

0

High-throughput

0.279

Low

320593

GGPPS
Geranylgeranyl pyrophosphate synthase

1

0

High-throughput

0.279

Low

352353

ATX3
Ataxin-3

1

0

High-throughput

0.279

Low

352367

NRK2
Nicotinamide riboside kinase 2

1

0

High-throughput

0.265

Low

352366

TRI31
E3 ubiquitin-protein ligase TRIM31

1

0

High-throughput

0.249

Low

352368

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024