Protein: TRIB2
Tribbles homolog 2 (TRB-2)

Gene: TRIB2
Organism: Homo sapiens
Interactions: 49
UniProt ID: Q92519

Gene Ontology (top 5):
GO:0004860 - protein kinase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005856 - cytoskeleton
GO:0006469 - negative regulation of protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

60382

POTEF
POTE ankyrin domain family member F

2

8

High-throughput

0.811

High

1266262

TRIB1
Tribbles homolog 1

2

17

High-throughput

0.811

High

1231631

STK40
Serine/threonine-protein kinase 40

3

19

High-throughput

0.779

High

1246129

COP1
E3 ubiquitin-protein ligase COP1

5

9

Small-scale

0.718

High

801277

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.691

High

1049497

SAFB2
Scaffold attachment factor B2

1

7

High-throughput

0.691

High

1230002

RPTOR
Regulatory-associated protein of mTOR

1

10

High-throughput

0.691

High

1266261

RBM14
RNA-binding protein 14

1

6

High-throughput

0.691

High

1266271

RALY
RNA-binding protein Raly

1

4

High-throughput

0.691

High

1185066

DET1
DET1 homolog

3

2

High-throughput

0.675

High

1266272

FBW1A
F-box/WD repeat-containing protein 1A

3

7

Small-scale

0.674

High

1266269

UBQL4
Ubiquilin-4

1

7

High-throughput

0.656

High

1130387

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

High-throughput

0.647

High

499973

CH60
60 kDa heat shock protein, mitochondrial

2

8

High-throughput

0.628

High

851857

UB2E1
Ubiquitin-conjugating enzyme E2 E1

2

4

High-throughput

0.628

High

1133632

SKT
Sickle tail protein homolog

2

1

High-throughput

0.628

High

1266263

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

2

2

High-throughput

0.628

High

1266268

SLAF7
SLAM family member 7

1

1

High-throughput

0.625

High

1266267

SMUF1
E3 ubiquitin-protein ligase SMURF1

2

14

Small-scale

0.624

High

161421

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

5

Small-scale

0.618

High

616723

KS6B1
Ribosomal protein S6 kinase beta-1

1

15

Small-scale

0.618

High

1266265

PARVG
Gamma-parvin

2

5

High-throughput

0.606

High

966268

TFAP4
Transcription factor AP-4

2

0

High-throughput

0.602

High

171875

GSTA4
Glutathione S-transferase A4

2

3

High-throughput

0.574

High

1116793

KCD21
BTB/POZ domain-containing protein KCTD21

2

2

High-throughput

0.574

High

260951

H2AY
Core histone macro-H2A.1

1

3

High-throughput

0.536

High

564979

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.536

High

946275

BASP1
Brain acid soluble protein 1

1

4

High-throughput

0.536

High

1242088

LS14A
Protein LSM14 homolog A

1

1

High-throughput

0.536

High

1266264

DHRS6
Dehydrogenase/reductase SDR family member 6

1

1

High-throughput

0.536

High

1266270

BCLF1
Bcl-2-associated transcription factor 1

1

3

High-throughput

0.536

High

1266273

TR150
Thyroid hormone receptor-associated protein 3

1

4

High-throughput

0.536

High

644109

EF1G
Elongation factor 1-gamma

1

5

High-throughput

0.515

High

1191500

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

4

High-throughput

0.515

High

509072

TOP2A
DNA topoisomerase 2-alpha

1

0

High-throughput

0.513

High

1266274

CHTOP
Chromatin target of PRMT1 protein

1

0

High-throughput

0.513

High

1266260

ANM6
Protein arginine N-methyltransferase 6

1

4

High-throughput

0.508

High

395350

A4
Amyloid-beta precursor protein

1

10

High-throughput

0.501

High

831529

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

Small-scale

0.501

High

1088578

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.489

High

455709

PARP1
Poly [ADP-ribose] polymerase 1

1

7

Small-scale

0.479

High

502380

BIP
Endoplasmic reticulum chaperone BiP

1

8

Small-scale

0.479

High

585023

RO52
E3 ubiquitin-protein ligase TRIM21

1

1

Small-scale

0.479

High

1041119

CUL1
Cullin-1

1

7

Small-scale

0.479

High

1072144

PCBP2
Poly(rC)-binding protein 2

1

5

Small-scale

0.479

High

1266266

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

Small-scale

0.458

High

1024059

ACACA
Acetyl-CoA carboxylase 1

1

8

Small-scale

0.457

High

1235091

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.279

Low

1125553

CAR16
Caspase recruitment domain-containing protein 16

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024