Protein: ORAI1
Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A)

Gene: ORAI1
Organism: Homo sapiens
Interactions: 45
UniProt ID: Q96D31

Gene Ontology (top 5):
GO:0002115 - store-operated calcium entry
GO:0002250 - adaptive immune response
GO:0005262 - calcium channel activity
GO:0005516 - calmodulin binding
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1287778

ORAI1
Calcium release-activated calcium channel protein 1

5

2

Small-scale

0.914

High

1287781

ORAI3
Protein orai-3

2

2

Small-scale

0.768

High

1040212

STIM1
Stromal interaction molecule 1

10

6

Small-scale

0.755

High

798445

LPAR6
Lysophosphatidic acid receptor 6

3

1

High-throughput

0.667

High

1255252

HAVR2
Hepatitis A virus cellular receptor 2

1

0

High-throughput

0.656

High

1287782

EFC4B
EF-hand calcium-binding domain-containing protein 4B

1

2

Small-scale

0.569

High

1037186

TRPC3
Short transient receptor potential channel 3

1

3

Small-scale

0.561

High

370173

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

980118

ATP7A
Copper-transporting ATPase 1

1

1

High-throughput

0.536

High

1202619

S22AG
Solute carrier family 22 member 16

1

1

High-throughput

0.536

High

1287783

S22A4
Solute carrier family 22 member 4

1

1

High-throughput

0.536

High

1287790

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

1

High-throughput

0.536

High

60390

POTEF
POTE ankyrin domain family member F

1

0

High-throughput

0.513

High

234847

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.513

High

801627

S15A1
Solute carrier family 15 member 1

1

0

High-throughput

0.513

High

813970

GPR12
G-protein coupled receptor 12

1

0

High-throughput

0.513

High

814295

GLR
Glucagon receptor

1

0

High-throughput

0.513

High

895705

CXCR4
C-X-C chemokine receptor type 4

1

0

High-throughput

0.513

High

1139418

ECM29
Proteasome adapter and scaffold protein ECM29

1

0

High-throughput

0.513

High

1147992

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

0

High-throughput

0.513

High

1232000

S35F6
Solute carrier family 35 member F6

1

0

High-throughput

0.513

High

1260042

CHPT1
Cholinephosphotransferase 1

1

0

High-throughput

0.513

High

1287554

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.513

High

1287786

GHITM
Growth hormone-inducible transmembrane protein

1

0

High-throughput

0.513

High

257855

AT2C2
Calcium-transporting ATPase type 2C member 2

1

0

Small-scale

0.512

High

1287791

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

1

High-throughput

0.489

High

823182

TRPC1
Short transient receptor potential channel 1

1

3

Small-scale

0.479

High

1189576

UBE3B
Ubiquitin-protein ligase E3B

1

1

High-throughput

0.470

High

1287789

UBQL1
Ubiquilin-1

1

0

Small-scale

0.458

High

1135427

WLS
Protein wntless homolog

1

0

Small-scale

0.438

High

1287131

FAF2
FAS-associated factor 2

2

0

High-throughput

0.318

High

882194

DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

1

0

High-throughput

0.279

Low

933305

TBA1B
Tubulin alpha-1B chain

1

0

High-throughput

0.279

Low

1037352

TBB3
Tubulin beta-3 chain

1

0

High-throughput

0.279

Low

1167858

HACD2
Very-long-chain

1

0

High-throughput

0.279

Low

1264033

CBPA5
Carboxypeptidase A5

1

0

High-throughput

0.279

Low

1284727

TTC28
Tetratricopeptide repeat protein 28

1

0

High-throughput

0.279

Low

1287780

CP2S1
Cytochrome P450 2S1

1

0

High-throughput

0.279

Low

1287784

SHRPN
Sharpin

1

0

High-throughput

0.279

Low

1287785

5NT3A
Cytosolic 5'-nucleotidase 3A

1

0

High-throughput

0.279

Low

1287788

INT7
Integrator complex subunit 7

1

0

High-throughput

0.279

Low

1237237

EFHB
EF-hand domain-containing family member B

1

0

Small-scale

0.249

Low

1287779

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

0

Small-scale

0.249

Low

1287787

BPIA1
BPI fold-containing family A member 1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024