Protein: LCFC1
Sperm-egg fusion protein LLCFC1 (LLLL and CFNLAS motif-containing protein 1) (MSSP-binding protein CTM-1) (Sperm-oocyte fusion required protein 1)

Gene: LCFC1, LLCFC1
Organism: Homo sapiens
Interactions: 120
UniProt ID: Q96L11

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0007342 - fusion of sperm to egg plasma membrane involved in single fertilization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

129819

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

3

High-throughput

0.536

High

135826

MA2B1
Lysosomal alpha-mannosidase

1

2

High-throughput

0.536

High

172698

LAMA5
Laminin subunit alpha-5

1

3

High-throughput

0.536

High

423093

PROS
Vitamin K-dependent protein S

1

7

High-throughput

0.536

High

508153

FGFR1
Fibroblast growth factor receptor 1

1

1

High-throughput

0.536

High

550475

ARSB
Arylsulfatase B

1

4

High-throughput

0.536

High

709273

GALNS
N-acetylgalactosamine-6-sulfatase

1

4

High-throughput

0.536

High

1017598

FSTL1
Follistatin-related protein 1

1

1

High-throughput

0.536

High

1053527

GAS6
Growth arrest-specific protein 6

1

4

High-throughput

0.536

High

1087526

LAMA3
Laminin subunit alpha-3

1

2

High-throughput

0.536

High

1165662

ARSK
Arylsulfatase K

1

4

High-throughput

0.536

High

1204030

CHSS1
Chondroitin sulfate synthase 1

1

2

High-throughput

0.536

High

1219517

SULF2
Extracellular sulfatase Sulf-2

1

4

High-throughput

0.536

High

1231525

VWDE
von Willebrand factor D and EGF domain-containing protein

1

2

High-throughput

0.536

High

1296619

CNTP3
Contactin-associated protein-like 3

1

4

High-throughput

0.536

High

1296633

EGFL7
Epidermal growth factor-like protein 7

1

7

High-throughput

0.536

High

245832

CATL2
Cathepsin L2

1

0

High-throughput

0.513

High

528126

BMP1
Bone morphogenetic protein 1

1

0

High-throughput

0.513

High

726534

TIMP3
Metalloproteinase inhibitor 3

1

0

High-throughput

0.513

High

738929

PEDF
Pigment epithelium-derived factor

1

0

High-throughput

0.513

High

782095

WNT5A
Protein Wnt-5a

1

0

High-throughput

0.513

High

849064

GPC3
Glypican-3

1

0

High-throughput

0.513

High

872565

EPHB4
Ephrin type-B receptor 4

1

0

High-throughput

0.513

High

874459

PLTP
Phospholipid transfer protein

1

0

High-throughput

0.513

High

902281

NPC2
NPC intracellular cholesterol transporter 2

1

0

High-throughput

0.513

High

984723

COEA1
Collagen alpha-1(XIV) chain

1

0

High-throughput

0.513

High

1048424

NID2
Nidogen-2

1

0

High-throughput

0.513

High

1268530

PXDN
Peroxidasin homolog

1

0

High-throughput

0.513

High

1296615

APOL2
Apolipoprotein L2

1

0

High-throughput

0.513

High

1296618

EMIL2
EMILIN-2

1

0

High-throughput

0.513

High

1296632

GAK1A
Golgi-associated kinase 1A

1

0

High-throughput

0.513

High

1296637

HYOU1
Hypoxia up-regulated protein 1

1

0

High-throughput

0.513

High

152099

TOR1B
Torsin-1B

1

3

High-throughput

0.489

High

165238

PLXB2
Plexin-B2

1

2

High-throughput

0.489

High

206920

CHSTA
Carbohydrate sulfotransferase 10

1

1

High-throughput

0.489

High

217200

EXTL3
Exostosin-like 3

1

1

High-throughput

0.489

High

253495

PLXA2
Plexin-A2

1

1

High-throughput

0.489

High

312867

GDF11
Growth/differentiation factor 11

1

1

High-throughput

0.489

High

530724

ITA4
Integrin alpha-4

1

3

High-throughput

0.489

High

566897

ITA2
Integrin alpha-2

1

4

High-throughput

0.489

High

830100

MA2A2
Alpha-mannosidase 2x

1

2

High-throughput

0.489

High

864320

ITA8
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]

1

3

High-throughput

0.489

High

869974

CA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1

1

1

High-throughput

0.489

High

885348

INHBE
Inhibin beta E chain

1

1

High-throughput

0.489

High

942478

CNTP1
Contactin-associated protein 1

1

4

High-throughput

0.489

High

1037357

TBB3
Tubulin beta-3 chain

1

1

High-throughput

0.489

High

1044844

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

3

High-throughput

0.489

High

1055004

FAT1
Protocadherin Fat 1

1

3

High-throughput

0.489

High

1081868

EXT1
Exostosin-1

1

1

High-throughput

0.489

High

1086408

MA2A1
Alpha-mannosidase 2

1

2

High-throughput

0.489

High

1114192

TBB8
Tubulin beta-8 chain

1

1

High-throughput

0.489

High

1167032

FAT4
Protocadherin Fat 4

1

3

High-throughput

0.489

High

1175106

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.489

High

1190430

PLGT3
Protein O-glucosyltransferase 3

1

1

High-throughput

0.489

High

1219552

SULF1
Extracellular sulfatase Sulf-1

1

4

High-throughput

0.489

High

1223959

CHSS2
Chondroitin sulfate synthase 2

1

2

High-throughput

0.489

High

1240004

PGLT1
Protein O-glucosyltransferase 1

1

1

High-throughput

0.489

High

1267994

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

1

High-throughput

0.489

High

1295687

PCD16
Protocadherin-16

1

3

High-throughput

0.489

High

1296614

TBA1C
Tubulin alpha-1C chain

1

1

High-throughput

0.489

High

1296616

LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3

1

1

High-throughput

0.489

High

1296621

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

1

High-throughput

0.489

High

1296622

TOR3A
Torsin-3A

1

3

High-throughput

0.489

High

1296623

CHSTC
Carbohydrate sulfotransferase 12

1

1

High-throughput

0.489

High

1296625

CA2D2
Voltage-dependent calcium channel subunit alpha-2/delta-2

1

1

High-throughput

0.489

High

1296626

CELR3
Cadherin EGF LAG seven-pass G-type receptor 3

1

3

High-throughput

0.489

High

1296628

TEN3
Teneurin-3

1

2

High-throughput

0.489

High

1296629

CHPF2
Chondroitin sulfate glucuronyltransferase

1

2

High-throughput

0.489

High

1296630

DNJB9
DnaJ homolog subfamily B member 9

1

1

High-throughput

0.489

High

1296631

CATF
Cathepsin F

1

1

High-throughput

0.489

High

1231540

TOR2X
Prosalusin

1

3

High-throughput

0.479

High

1128308

TOR2A
Torsin-2A

1

3

High-throughput

0.407

High

485277

TZAP
Telomere zinc finger-associated protein

1

0

High-throughput

0.282

High

529577

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.282

High

60396

POTEF
POTE ankyrin domain family member F

1

0

High-throughput

0.279

Low

279335

DNJB5
DnaJ homolog subfamily B member 5

1

0

High-throughput

0.279

Low

282424

STC2
Stanniocalcin-2

1

0

High-throughput

0.279

Low

397477

ADT2
ADP/ATP translocase 2

1

0

High-throughput

0.279

Low

562484

CBPE
Carboxypeptidase E

1

0

High-throughput

0.279

Low

567453

ASM
Sphingomyelin phosphodiesterase

1

0

High-throughput

0.279

Low

607771

ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

1

0

High-throughput

0.279

Low

723779

IDUA
Alpha-L-iduronidase

1

0

High-throughput

0.279

Low

792213

ECE1
Endothelin-converting enzyme 1

1

0

High-throughput

0.279

Low

871951

AT12A
Potassium-transporting ATPase alpha chain 2

1

0

High-throughput

0.279

Low

872955

ANAG
Alpha-N-acetylglucosaminidase

1

0

High-throughput

0.279

Low

919480

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.279

Low

962694

B4GN1
Beta-1,4 N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.279

Low

998433

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

0

High-throughput

0.279

Low

1019234

HYAL2
Hyaluronidase-2

1

0

High-throughput

0.279

Low

1055242

ERG1
Squalene monooxygenase

1

0

High-throughput

0.279

Low

1057188

MELK
Maternal embryonic leucine zipper kinase

1

0

High-throughput

0.279

Low

1058621

MBTP1
Membrane-bound transcription factor site-1 protease

1

0

High-throughput

0.279

Low

1069043

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.279

Low

1099380

T132A
Transmembrane protein 132A

1

0

High-throughput

0.279

Low

1117593

PLCH1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1

1

0

High-throughput

0.279

Low

1126669

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.279

Low

1129476

EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase

1

0

High-throughput

0.279

Low

1147587

SE1L3
Protein sel-1 homolog 3

1

0

High-throughput

0.279

Low

1165072

MOXD1
DBH-like monooxygenase protein 1

1

0

High-throughput

0.279

Low

1174920

TMUB2
Transmembrane and ubiquitin-like domain-containing protein 2

1

0

High-throughput

0.279

Low

1204311

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.279

Low

1205460

ERO1B
ERO1-like protein beta

1

0

High-throughput

0.279

Low

1231766

NLGN1
Neuroligin-1

1

0

High-throughput

0.279

Low

1232720

LARG2
Xylosyl- and glucuronyltransferase LARGE2

1

0

High-throughput

0.279

Low

1264265

BRI3B
BRI3-binding protein

1

0

High-throughput

0.279

Low

1266826

TM131
Transmembrane protein 131

1

0

High-throughput

0.279

Low

1286044

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

1291350

S47A1
Multidrug and toxin extrusion protein 1

1

0

High-throughput

0.279

Low

1296502

LMLN
Leishmanolysin-like peptidase

1

0

High-throughput

0.279

Low

1296611

HPLN3
Hyaluronan and proteoglycan link protein 3

1

0

High-throughput

0.279

Low

1296612

S29A1
Equilibrative nucleoside transporter 1

1

0

High-throughput

0.279

Low

1296613

SEM3C
Semaphorin-3C

1

0

High-throughput

0.279

Low

1296617

ABHEA
Protein ABHD14A

1

0

High-throughput

0.279

Low

1296620

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.279

Low

1296624

KLH11
Kelch-like protein 11

1

0

High-throughput

0.279

Low

1296627

EMC3
ER membrane protein complex subunit 3

1

0

High-throughput

0.279

Low

1296634

CEIP2
Inactive cell surface hyaluronidase CEMIP2

1

0

High-throughput

0.279

Low

1296635

METRN
Meteorin

1

0

High-throughput

0.279

Low

1296636

CCPG1
Cell cycle progression protein 1

1

0

High-throughput

0.279

Low

1296638

FLVC1
Heme transporter FLVCR1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024