Protein: HDAC7
Histone deacetylase 7 (HD7) (EC 3.5.1.98) (Histone deacetylase 7A) (HD7a) (Protein deacetylase HDAC7) (EC 3.5.1.-)

Gene: HDAC7
Organism: Homo sapiens
Interactions: 138
UniProt ID: Q8WUI4

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001570 - vasculogenesis
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1260208

NCOR2
Nuclear receptor corepressor 2

3

20

Small-scale

0.847

High

177340

HDAC3
Histone deacetylase 3

2

17

Small-scale

0.825

High

261554

NCOR1
Nuclear receptor corepressor 1

2

20

Small-scale

0.825

High

1260169

HDAC7
Histone deacetylase 7

2

18

Small-scale

0.768

High

1260171

HDAC2
Histone deacetylase 2

2

20

Small-scale

0.768

High

647138

1433T
14-3-3 protein theta

7

20

Small-scale

0.747

High

982322

1433F
14-3-3 protein eta

7

20

Small-scale

0.746

High

904911

1433G
14-3-3 protein gamma

6

20

High-throughput

0.734

High

1025478

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

5

20

High-throughput

0.720

High

683574

1433B
14-3-3 protein beta/alpha

5

20

Small-scale

0.716

High

927340

1433Z
14-3-3 protein zeta/delta

5

20

Small-scale

0.716

High

717231

CTNB1
Catenin beta-1

5

20

Small-scale

0.702

High

909856

1433E
14-3-3 protein epsilon

4

12

Small-scale

0.686

High

968793

MEF2A
Myocyte-specific enhancer factor 2A

4

20

Small-scale

0.680

High

981659

REL
Proto-oncogene c-Rel

3

20

High-throughput

0.675

High

322019

ZMYM6
Zinc finger MYM-type protein 6

3

8

High-throughput

0.667

High

834498

HINT1
Adenosine 5'-monophosphoramidase HINT1

3

1

High-throughput

0.667

High

1129889

DCA10
DDB1- and CUL4-associated factor 10

3

18

High-throughput

0.667

High

1260176

MOCOS
Molybdenum cofactor sulfurase

3

1

High-throughput

0.667

High

1260189

ADNP
Activity-dependent neuroprotector homeobox protein

3

1

High-throughput

0.667

High

1260203

TTF2
Transcription termination factor 2

3

20

High-throughput

0.667

High

684233

1433S
14-3-3 protein sigma

3

20

Small-scale

0.662

High

338747

EGFR
Epidermal growth factor receptor

3

15

High-throughput

0.656

High

880792

HDAC4
Histone deacetylase 4

1

18

Small-scale

0.647

High

1038570

HDAC1
Histone deacetylase 1

1

18

Small-scale

0.647

High

1260204

HDAC5
Histone deacetylase 5

1

18

Small-scale

0.647

High

1000258

RIPP1
Protein ripply1

3

0

High-throughput

0.646

High

987223

MEF2C
Myocyte-specific enhancer factor 2C

3

20

Small-scale

0.641

High

1159761

WDR73
WD repeat-containing protein 73

3

0

High-throughput

0.638

High

1260188

ZY11B
Protein zyg-11 homolog B

3

0

High-throughput

0.638

High

900733

RHOA
Transforming protein RhoA

2

8

High-throughput

0.628

High

1085616

HIF1A
Hypoxia-inducible factor 1-alpha

2

11

Small-scale

0.620

High

925469

RAC1
Ras-related C3 botulinum toxin substrate 1

2

8

High-throughput

0.615

High

135654

NDKM
Nucleoside diphosphate kinase, mitochondrial

2

4

High-throughput

0.606

High

545523

RAC2
Ras-related C3 botulinum toxin substrate 2

2

8

High-throughput

0.606

High

892506

RAC3
Ras-related C3 botulinum toxin substrate 3

2

8

High-throughput

0.606

High

894252

CDC42
Cell division control protein 42 homolog

2

8

High-throughput

0.606

High

978219

ARI5A
AT-rich interactive domain-containing protein 5A

2

20

High-throughput

0.606

High

1260170

ACO11
Acyl-coenzyme A thioesterase 11

2

2

High-throughput

0.606

High

1260177

PP16A
Protein phosphatase 1 regulatory subunit 16A

2

7

High-throughput

0.606

High

1260184

KLF16
Krueppel-like factor 16

2

20

High-throughput

0.606

High

1260194

BRWD1
Bromodomain and WD repeat-containing protein 1

2

20

High-throughput

0.606

High

1260186

KPCD2
Serine/threonine-protein kinase D2

1

16

Small-scale

0.596

High

1260181

NRIP2
Nuclear receptor-interacting protein 2

2

0

High-throughput

0.589

High

1088330

UGPA
UTP--glucose-1-phosphate uridylyltransferase

2

0

High-throughput

0.585

High

668851

PML
Protein PML

2

20

Small-scale

0.584

High

877811

FOXA1
Hepatocyte nuclear factor 3-alpha

2

14

Small-scale

0.584

High

210840

LDB2
LIM domain-binding protein 2

2

0

High-throughput

0.580

High

313674

TIAF1
Putative TGFB1-induced anti-apoptotic factor 1

2

0

High-throughput

0.580

High

1184455

CENPQ
Centromere protein Q

2

0

High-throughput

0.580

High

1260175

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.580

High

1260182

MIEN1
Migration and invasion enhancer 1

2

0

High-throughput

0.580

High

211623

ACTN4
Alpha-actinin-4

1

8

Small-scale

0.573

High

1059329

CASP8
Caspase-8

1

6

Small-scale

0.569

High

647931

MARK3
MAP/microtubule affinity-regulating kinase 3

1

9

Small-scale

0.561

High

781402

BCL6
B-cell lymphoma 6 protein

1

8

Small-scale

0.561

High

930313

UBC9
SUMO-conjugating enzyme UBC9

1

8

Small-scale

0.561

High

930935

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

16

Small-scale

0.561

High

1047422

RUNX2
Runt-related transcription factor 2

1

16

Small-scale

0.561

High

1183081

MARK2
Serine/threonine-protein kinase MARK2

1

11

Small-scale

0.561

High

62374

GG6L9
Golgin subfamily A member 6-like protein 9

2

17

High-throughput

0.553

High

179111

MOT4
Monocarboxylate transporter 4

2

5

High-throughput

0.553

High

301307

MTCL2
Microtubule cross-linking factor 2

2

20

High-throughput

0.553

High

305860

UBL3
Ubiquitin-like protein 3

2

1

High-throughput

0.553

High

905440

RRAS2
Ras-related protein R-Ras2

2

10

High-throughput

0.553

High

1260197

GBG12

2

1

High-throughput

0.553

High

1260172

KAT5
Histone acetyltransferase KAT5

1

5

Small-scale

0.552

High

245622

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

20

High-throughput

0.536

High

1260185

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

20

High-throughput

0.536

High

1260187

FOXP3
Forkhead box protein P3

1

20

Small-scale

0.534

High

626714

EDNRA
Endothelin-1 receptor

1

1

Small-scale

0.523

High

61106

A5PKX9
INADL protein

1

10

High-throughput

0.515

High

81917

B7ZLY0
PHC2 protein

1

12

High-throughput

0.515

High

1151147

Q6FHY5
MEOX2 protein

1

7

High-throughput

0.515

High

1118391

ZNG1F
Zinc-regulated GTPase metalloprotein activator 1F

1

0

High-throughput

0.513

High

132965

SDCB1
Syntenin-1

1

7

Small-scale

0.501

High

476103

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

16

High-throughput

0.501

High

788218

CASP3
Caspase-3

1

6

Small-scale

0.501

High

876958

CASP7
Caspase-7

1

6

Small-scale

0.501

High

876993

CASP9
Caspase-9

1

6

Small-scale

0.501

High

877106

CASP6
Caspase-6

1

6

Small-scale

0.501

High

984001

ZBT16
Zinc finger and BTB domain-containing protein 16

1

10

Small-scale

0.501

High

1058908

GNMT
Glycine N-methyltransferase

1

0

High-throughput

0.486

High

838161

MEOX2
Homeobox protein MOX-2

1

7

High-throughput

0.481

High

1220862

PHC2
Polyhomeotic-like protein 2

1

12

High-throughput

0.481

High

1246412

INADL
InaD-like protein

1

10

High-throughput

0.481

High

161415

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

9

Small-scale

0.479

High

196484

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

2

High-throughput

0.479

High

204200

KLF4
Krueppel-like factor 4

1

20

Small-scale

0.479

High

228169

PRKN
E3 ubiquitin-protein ligase parkin

1

17

High-throughput

0.479

High

230898

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

7

High-throughput

0.479

High

237278

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

1

High-throughput

0.479

High

253386

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

10

High-throughput

0.479

High

264367

GGYF1
GRB10-interacting GYF protein 1

1

8

High-throughput

0.479

High

370083

ESR1
Estrogen receptor

1

20

Small-scale

0.479

High

455692

PARP1
Poly [ADP-ribose] polymerase 1

1

18

High-throughput

0.479

High

487612

ANDR
Androgen receptor

1

20

Small-scale

0.479

High

644295

TTP
mRNA decay activator protein ZFP36

1

5

Small-scale

0.479

High

906544

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

13

Small-scale

0.479

High

998913

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.479

High

1028010

ERCC8
DNA excision repair protein ERCC-8

1

20

Small-scale

0.479

High

1033686

IKZF1
DNA-binding protein Ikaros

1

20

Small-scale

0.479

High

1058256

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

9

Small-scale

0.479

High

1060580

ZN638
Zinc finger protein 638

1

6

High-throughput

0.479

High

1068482

KPCD1
Serine/threonine-protein kinase D1

1

17

Small-scale

0.479

High

1125892

BCORL
BCL-6 corepressor-like protein 1

1

10

Small-scale

0.479

High

1136531

SPD2A
SH3 and PX domain-containing protein 2A

1

7

High-throughput

0.479

High

1170976

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.479

High

1217967

KSR1
Kinase suppressor of Ras 1

1

7

High-throughput

0.479

High

1221595

SMC5
Structural maintenance of chromosomes protein 5

1

15

High-throughput

0.479

High

1230488

CCAR2
Cell cycle and apoptosis regulator protein 2

1

5

Small-scale

0.479

High

1256241

DEN1A
DENN domain-containing protein 1A

1

8

High-throughput

0.479

High

1260173

FBXW7
F-box/WD repeat-containing protein 7

1

15

Small-scale

0.479

High

1260178

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

11

High-throughput

0.479

High

1260179

TESK2
Dual specificity testis-specific protein kinase 2

1

2

High-throughput

0.479

High

1260183

RTKN
Rhotekin

1

1

High-throughput

0.479

High

1260190

IKZF4
Zinc finger protein Eos

1

20

Small-scale

0.479

High

1260192

KI13B
Kinesin-like protein KIF13B

1

11

High-throughput

0.479

High

1260193

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

5

High-throughput

0.479

High

1260198

KDM5B
Lysine-specific demethylase 5B

1

18

Small-scale

0.479

High

1260199

LIMA1
LIM domain and actin-binding protein 1

1

8

High-throughput

0.479

High

1260200

IKZF3
Zinc finger protein Aiolos

1

20

Small-scale

0.479

High

1260201

ZBT21
Zinc finger and BTB domain-containing protein 21

1

6

High-throughput

0.479

High

1260202

PPM1H
Protein phosphatase 1H

1

3

High-throughput

0.479

High

1260205

CBY1
Protein chibby homolog 1

1

2

High-throughput

0.479

High

1260206

NR2E1
Nuclear receptor subfamily 2 group E member 1

1

20

Small-scale

0.479

High

898045

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.460

High

854114

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

1

0

High-throughput

0.458

High

166590

DCLK1
Serine/threonine-protein kinase DCLK1

1

13

High-throughput

0.437

High

1260195

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

3

High-throughput

0.437

High

1260196

CING
Cingulin

1

16

High-throughput

0.437

High

1260207

KCTD3
BTB/POZ domain-containing protein KCTD3

1

3

High-throughput

0.437

High

1260174

FWCH2
FLYWCH family member 2

3

0

High-throughput

0.347

High

1109964

CC036
Uncharacterized protein C3orf36

2

0

High-throughput

0.316

High

1169371

KRBA2
KRAB-A domain-containing protein 2

2

0

High-throughput

0.316

High

1260180

ANKMT
Adenine nucleotide translocase lysine N-methyltransferase

2

0

High-throughput

0.316

High

1260191

ESM1
Endothelial cell-specific molecule 1

2

0

High-throughput

0.316

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024